ATE478863T1 - Heterotetracyclische verbindungen als tpo- mimetica - Google Patents
Heterotetracyclische verbindungen als tpo- mimeticaInfo
- Publication number
- ATE478863T1 ATE478863T1 AT06787581T AT06787581T ATE478863T1 AT E478863 T1 ATE478863 T1 AT E478863T1 AT 06787581 T AT06787581 T AT 06787581T AT 06787581 T AT06787581 T AT 06787581T AT E478863 T1 ATE478863 T1 AT E478863T1
- Authority
- AT
- Austria
- Prior art keywords
- compounds
- tpomimetica
- heterotetracyclic
- heterotetracyclic compounds
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/94—[b, c]- or [b, d]-condensed containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/052—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J7/00—Chemical treatment or coating of shaped articles made of macromolecular substances
- C08J7/04—Coating
- C08J7/042—Coating with two or more layers, where at least one layer of a composition contains a polymer binder
- C08J7/0423—Coating with two or more layers, where at least one layer of a composition contains a polymer binder with at least one layer of inorganic material and at least one layer of a composition containing a polymer binder
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
- C08J2369/00—Characterised by the use of polycarbonates; Derivatives of polycarbonates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Polymers & Plastics (AREA)
- Hematology (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US69948105P | 2005-07-14 | 2005-07-14 | |
PCT/US2006/027691 WO2007009120A2 (en) | 2005-07-14 | 2006-07-14 | Heterotetracyclic compounds as tpo mimetics |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE478863T1 true ATE478863T1 (de) | 2010-09-15 |
Family
ID=37638014
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06787581T ATE478863T1 (de) | 2005-07-14 | 2006-07-14 | Heterotetracyclische verbindungen als tpo- mimetica |
Country Status (16)
Country | Link |
---|---|
US (1) | US8153671B2 (de) |
EP (1) | EP1910338B1 (de) |
JP (1) | JP5132554B2 (de) |
KR (1) | KR20080028929A (de) |
CN (1) | CN101213190A (de) |
AT (1) | ATE478863T1 (de) |
AU (1) | AU2006267077A1 (de) |
BR (1) | BRPI0613460A2 (de) |
CA (1) | CA2612442A1 (de) |
DE (1) | DE602006016449D1 (de) |
ES (1) | ES2351455T3 (de) |
MX (1) | MX2008000462A (de) |
PL (1) | PL1910338T3 (de) |
PT (1) | PT1910338E (de) |
RU (1) | RU2008105071A (de) |
WO (1) | WO2007009120A2 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2240481A1 (de) | 2008-01-11 | 2010-10-20 | Albany Molecular Research, Inc. | (1-azinon)-substituierte pyridoindole als mch-antagonisten |
PE20100362A1 (es) | 2008-10-30 | 2010-05-27 | Irm Llc | Derivados de purina que expanden las celulas madre hematopoyeticas |
US20190127365A1 (en) | 2017-11-01 | 2019-05-02 | Merck Sharp & Dohme Corp. | Inhibitors of hepatitis c virus replication |
ME02418B (de) | 2009-03-27 | 2016-09-20 | Merck Sharp & Dohme | Inhibitoren der replikation des hepatitis-c-virus |
WO2011003012A1 (en) | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azapolycycle mch-1 antagonists, methods of making, and use thereof |
US8629158B2 (en) | 2009-07-01 | 2014-01-14 | Albany Molecular Research, Inc. | Azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine MCH-1 antagonists, methods of making, and use thereof |
WO2011003005A1 (en) * | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azepino[b]indole and pyrido-pyrrolo-azepine mch-1 antagonists, methods of making, and use thereof |
WO2011003021A1 (en) * | 2009-07-01 | 2011-01-06 | Albany Molecular Research, Inc. | Azinone-substituted azabicycloalkane-indole and azabicycloalkane-pyrrolo-pyridine mch-1 antagonists, methods of making, and use thereof |
EP2305688A1 (de) | 2009-09-28 | 2011-04-06 | Université de la Méditerranée - Aix-Marseille II | Neuartige Aminosäurederivate, deren Herstellungsverfahren und deren therapeutische Verwendungen als MET-Inhibitoren |
WO2012050848A1 (en) | 2010-09-29 | 2012-04-19 | Schering Corporation | Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases |
WO2012088124A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Tetrahydro-azacarboline mch-1 antagonists, methods of making, and uses thereof |
WO2012088038A2 (en) | 2010-12-21 | 2012-06-28 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof |
WO2012102937A2 (en) | 2011-01-25 | 2012-08-02 | Irm Llc | Compounds that expand hematopoietic stem cells |
WO2012122716A1 (en) | 2011-03-17 | 2012-09-20 | Merck Sharp & Dohme Corp. | Tetracyclic xanthene derivatives and methods of use thereof for treatment of viral diseases |
US9834755B2 (en) | 2011-12-08 | 2017-12-05 | Fred Hutchinson Cancer Research Center | Compositions and methods for enhanced generation of hematopoietic stem/progenitor cells |
SG11201404241SA (en) | 2012-01-27 | 2014-08-28 | Univ Montreal | Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells |
WO2014110687A1 (en) | 2013-01-16 | 2014-07-24 | Merck Sharp & Dohme Corp. | Thiazolyl-substitued tetracyclic compounds and methods of use thereof for treatment of viral diseases |
EP3134409B1 (de) | 2014-04-22 | 2020-02-12 | Université de Montréal | Verbindungen und verwendung davon in der expansion von hämatopoietischen stammzellen und/oder hämatopoietischen vorläuferzellen |
CN106724598B (zh) * | 2017-02-28 | 2017-11-24 | 宁波圆明工业设计有限公司 | 一种含有滤料的水杯 |
IT201700100116A1 (it) * | 2017-09-07 | 2019-03-07 | Univ Pisa | Composti a struttura benzo[a]carbazolica e loro usi |
WO2024119067A1 (en) | 2022-12-02 | 2024-06-06 | Neumora Therapeutics, Inc. | Methods of treating neurological disorders |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6256471A (ja) | 1985-09-05 | 1987-03-12 | Teikoku Hormone Mfg Co Ltd | 含窒素四環式化合物 |
JPS62147462A (ja) | 1985-12-20 | 1987-07-01 | Canon Inc | 電子写真感光体 |
JPS63148267A (ja) | 1986-12-12 | 1988-06-21 | Canon Inc | 電子写真感光体 |
SE8902274D0 (sv) | 1989-06-22 | 1989-06-22 | Univ Cincinnati | Indenoidole compounds ii |
SE8902273D0 (sv) * | 1989-06-22 | 1989-06-22 | Univ Cincinnati | Indenoindole compounds i |
JPH06228554A (ja) | 1993-02-04 | 1994-08-16 | Toyo Ink Mfg Co Ltd | 有機エレクトロルミネッセンス素子 |
TW430660B (en) | 1996-05-30 | 2001-04-21 | Mochida Pharm Co Ltd | Novel benzindole derivatives for neuron cell protection, processes for production, and the pharmaceutical compounds containing them |
JPH11322756A (ja) | 1998-03-17 | 1999-11-24 | Nippon Soda Co Ltd | ベンゾチオピラノインドール化合物および農園芸用殺菌剤 |
EP1135393A2 (de) | 1998-12-04 | 2001-09-26 | American Home Products Corporation | Substituierte benzofuranindole und indenoindole als kalium kanalaktivatoren |
US6288099B1 (en) * | 1998-12-04 | 2001-09-11 | American Home Products Corporation | Substituted benzofuranoindoles and indenoindoles as novel potassium channel openers |
ATE261963T1 (de) | 1999-01-11 | 2004-04-15 | Agouron Pharma | Tricyclische inhibitoren von poly(adp-ribose) polymerasen |
AU2079901A (en) | 1999-12-06 | 2001-06-12 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
US20060084682A1 (en) | 2002-12-13 | 2006-04-20 | Heerding Dirk A | Thrombopoietin mimetics |
JP5031570B2 (ja) * | 2004-09-20 | 2012-09-19 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | 性ステロイドホルモン受容体モジュレーターとして有用な新規な四環式ヘテロ原子含有誘導体 |
-
2006
- 2006-07-14 MX MX2008000462A patent/MX2008000462A/es not_active Application Discontinuation
- 2006-07-14 PL PL06787581T patent/PL1910338T3/pl unknown
- 2006-07-14 RU RU2008105071/04A patent/RU2008105071A/ru not_active Application Discontinuation
- 2006-07-14 ES ES06787581T patent/ES2351455T3/es active Active
- 2006-07-14 BR BRPI0613460-2A patent/BRPI0613460A2/pt not_active IP Right Cessation
- 2006-07-14 DE DE602006016449T patent/DE602006016449D1/de active Active
- 2006-07-14 JP JP2008521705A patent/JP5132554B2/ja not_active Expired - Fee Related
- 2006-07-14 KR KR1020087000926A patent/KR20080028929A/ko not_active Application Discontinuation
- 2006-07-14 PT PT06787581T patent/PT1910338E/pt unknown
- 2006-07-14 US US11/995,683 patent/US8153671B2/en not_active Expired - Fee Related
- 2006-07-14 CA CA002612442A patent/CA2612442A1/en not_active Abandoned
- 2006-07-14 CN CNA2006800243384A patent/CN101213190A/zh active Pending
- 2006-07-14 EP EP06787581A patent/EP1910338B1/de not_active Not-in-force
- 2006-07-14 AU AU2006267077A patent/AU2006267077A1/en not_active Abandoned
- 2006-07-14 WO PCT/US2006/027691 patent/WO2007009120A2/en active Application Filing
- 2006-07-14 AT AT06787581T patent/ATE478863T1/de active
Also Published As
Publication number | Publication date |
---|---|
JP5132554B2 (ja) | 2013-01-30 |
BRPI0613460A2 (pt) | 2011-01-11 |
EP1910338A2 (de) | 2008-04-16 |
US8153671B2 (en) | 2012-04-10 |
WO2007009120A3 (en) | 2007-05-03 |
MX2008000462A (es) | 2008-03-10 |
US20090075996A1 (en) | 2009-03-19 |
RU2008105071A (ru) | 2009-08-20 |
KR20080028929A (ko) | 2008-04-02 |
AU2006267077A1 (en) | 2007-01-18 |
JP2009501728A (ja) | 2009-01-22 |
PL1910338T3 (pl) | 2011-02-28 |
CN101213190A (zh) | 2008-07-02 |
WO2007009120A2 (en) | 2007-01-18 |
CA2612442A1 (en) | 2007-01-18 |
PT1910338E (pt) | 2010-12-02 |
EP1910338B1 (de) | 2010-08-25 |
ES2351455T3 (es) | 2011-02-04 |
DE602006016449D1 (de) | 2010-10-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE478863T1 (de) | Heterotetracyclische verbindungen als tpo- mimetica | |
MX2008002166A (es) | Compuestos y composiciones como mimeticos de trombopoietina (tpo). | |
ATE482209T1 (de) | Verbindungen und zusammensetzungen als modulatoren der gpr119-aktivität | |
EA200901032A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
EA200900828A1 (ru) | Соединения и композиции в качестве ингибиторов активности каннабиноидного рецептора 1 | |
TN2012000081A1 (en) | Compounds and compositions as protein kinase inhibitors | |
TN2010000122A1 (en) | Compounds and compositions as modulators of gpr119 activity | |
MX2007009356A (es) | Compuestos y composiciones como moduladores de ppar. | |
BRPI0517015A (pt) | compostos e composições como inibidores de atividade de receptor 1 de canabinóide | |
MX2009000285A (es) | Piperidinas sustituidas que incrementan la actividad de p53 y usos de las mismas. | |
EA200970447A1 (ru) | Соединения и композиции в качестве ингибиторов протеинкиназы | |
PT1984357E (pt) | Compostos de 2,4-pirimidinadiamina para tratamento ou prevenção de doenças autoimunes | |
ATE469895T1 (de) | Cgrp-rezeptorantagonisten | |
MX2009011951A (es) | Compuestos y composiciones como inhibidores de cinasa c-kit y pdgfr. | |
ATE445624T1 (de) | Verbindungen und zusammensetzungen als ppar- modulatoren | |
EA200900023A1 (ru) | Применение замещенных 2-аминотетралинов для изготовления лекарственного средства для предупреждения, облегчения и/или лечения разных видов боли | |
MX2009007944A (es) | Compuestos y composiciones de purina como inhibidores de quinasa para el tratamiento de enfermedades relacionadas con plasmodium. | |
TW200800968A (en) | Sulfoximine-substituted pyrimidines, processes for production thereof and use thereof as drugs | |
EA201001329A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
EA201100138A1 (ru) | 4-феноксиметилпиперидины в качестве модуляторов активности gpr119 | |
MX2009006170A (es) | Compuestos y composiciones como inhibidores de cinasa. | |
ATE544761T1 (de) | Pyrimidinderivate und zusammensetzungen als c-kit-und pdgfr-kinasehemmer | |
EA201001332A1 (ru) | Соединения и композиции в качестве модуляторов активности gpr119 | |
MX2009003981A (es) | Agentes moduladores del receptor de calcio. | |
BRPI0605926A2 (pt) | ciclopentanos substituìdos ou ciclopentanonas como agentes terapêuticos |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1910338 Country of ref document: EP |