ATE53606T1 - Mit einem herpes-simplex-virus-gen inseriertes rekombinantes plasmid. - Google Patents
Mit einem herpes-simplex-virus-gen inseriertes rekombinantes plasmid.Info
- Publication number
- ATE53606T1 ATE53606T1 AT86112005T AT86112005T ATE53606T1 AT E53606 T1 ATE53606 T1 AT E53606T1 AT 86112005 T AT86112005 T AT 86112005T AT 86112005 T AT86112005 T AT 86112005T AT E53606 T1 ATE53606 T1 AT E53606T1
- Authority
- AT
- Austria
- Prior art keywords
- herpes simplex
- simplex virus
- terminal
- recombinant plasmid
- region
- Prior art date
Links
- 239000013612 plasmid Substances 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000700584 Simplexvirus Species 0.000 title abstract 2
- 108700039691 Genetic Promoter Regions Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 208000009889 Herpes Simplex Diseases 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 101150029683 gB gene Proteins 0.000 abstract 1
- 239000013600 plasmid vector Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
- C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/911—Microorganisms using fungi
- Y10S435/94—Saccharomyces
- Y10S435/942—Saccharomyces cerevisiae
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP60192916A JPH0668B2 (ja) | 1985-08-30 | 1985-08-30 | 単純ヘルペスウイルス遺伝子が組込まれた組換えプラスミド |
EP86112005A EP0216195B1 (de) | 1985-08-30 | 1986-08-29 | Mit einem Herpes-simplex-Virus-Gen inseriertes rekombinantes Plasmid |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE53606T1 true ATE53606T1 (de) | 1990-06-15 |
Family
ID=16299111
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT86112005T ATE53606T1 (de) | 1985-08-30 | 1986-08-29 | Mit einem herpes-simplex-virus-gen inseriertes rekombinantes plasmid. |
Country Status (7)
Country | Link |
---|---|
US (1) | US5059538A (de) |
EP (1) | EP0216195B1 (de) |
JP (1) | JPH0668B2 (de) |
KR (1) | KR940005582B1 (de) |
AT (1) | ATE53606T1 (de) |
CA (1) | CA1295564C (de) |
DE (1) | DE3671916D1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0297924A3 (de) * | 1987-07-01 | 1990-07-11 | City Of Hope | Rekombinant vaccinia Virus zur Expression von HSV 1 gB |
DK0541692T3 (da) * | 1990-08-02 | 1999-11-01 | Chiron Corp | Herpes simplex virus VP-16-vacciner |
US6395470B2 (en) * | 1997-10-31 | 2002-05-28 | Cenetron Diagnostics, Llc | Method for monitoring nucleic acid assays using synthetic internal controls with reversed nucleotide sequences |
WO2011130749A2 (en) * | 2010-04-16 | 2011-10-20 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Identification of mutations in herpes simplex virus envelope glycoproteins that enable or enhance vector retargeting to novel non-hsv receptors |
WO2015066042A1 (en) | 2013-10-28 | 2015-05-07 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Oncolytic hsv vector |
CN116904404A (zh) | 2016-01-27 | 2023-10-20 | 昂克诺斯公司 | 溶瘤病毒载体及其用途 |
WO2018006005A1 (en) | 2016-06-30 | 2018-01-04 | Oncorus, Inc. | Pseudotyped oncolytic viral delivery of therapeutic polypeptides |
JP7249323B2 (ja) | 2017-07-26 | 2023-03-30 | オンコラス, インコーポレイテッド | 腫瘍溶解性ウイルスベクター及びその使用 |
EP3731850A4 (de) | 2017-12-29 | 2021-12-01 | Oncorus, Inc. | Onkolytische virale verabreichung von therapeutischen polypeptiden |
KR101998793B1 (ko) * | 2018-09-04 | 2019-07-10 | 의료법인 성광의료재단 | 재조합 단순 헤르페스 바이러스의 제조를 위한 벡터 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT77014B (en) * | 1982-07-20 | 1986-01-24 | Molecular Genetics Inc | Production of herpes simplex viral proteins |
DE3228501A1 (de) * | 1982-07-30 | 1984-02-02 | Behringwerke Ag, 3550 Marburg | Verfahren zur herstellung eines herpes-antigens, dazu geeignetes mittel sowie verfahren zu seiner herstellung und die verwendung dieses antigens |
US4661454A (en) * | 1983-02-28 | 1987-04-28 | Collaborative Research, Inc. | GAL1 yeast promoter linked to non galactokinase gene |
US4642333A (en) * | 1983-09-16 | 1987-02-10 | Stanley Person | Immunologically reactive non-glycosylated amino acid chains of glycoprotein B of herpes virus types 1 and 2 |
FR2556008B1 (fr) * | 1983-12-06 | 1987-06-26 | Centre Nat Rech Scient | Vecteurs plasmidiques de clonage et d'expression d'une proteine dans un micro-organisme, comportant au moins le promoteur d'expression de la b-glucosidase dans les levures; micro-organismes les contenant; procede de fermentation et enzymes obtenues |
JPS60197629A (ja) * | 1984-03-16 | 1985-10-07 | Chemo Sero Therapeut Res Inst | HBs抗原の精製方法 |
JPS615786A (ja) * | 1984-06-19 | 1986-01-11 | Chemo Sero Therapeut Res Inst | 単純ヘルペスウイルス遺伝子を組込んだ組換えdna、形質転換動物細胞および単純ヘルペスウイルス蛋白質の製法 |
EP0170169B1 (de) * | 1984-07-20 | 1991-03-20 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Rekombinante DNS, enthaltend ein Herpes-Simplex-Virus-Gen oder ein Fragment davon, Hefe transformiert mit dieser rekombinanten DNS und Verfahren zur Herstellung von Herpes-Simplex-Virus-Proteinen |
-
1985
- 1985-08-30 JP JP60192916A patent/JPH0668B2/ja not_active Expired - Fee Related
-
1986
- 1986-08-15 US US06/896,923 patent/US5059538A/en not_active Expired - Lifetime
- 1986-08-26 CA CA000516821A patent/CA1295564C/en not_active Expired - Fee Related
- 1986-08-29 AT AT86112005T patent/ATE53606T1/de not_active IP Right Cessation
- 1986-08-29 EP EP86112005A patent/EP0216195B1/de not_active Expired - Lifetime
- 1986-08-29 DE DE8686112005T patent/DE3671916D1/de not_active Expired - Lifetime
- 1986-08-29 KR KR1019860007220A patent/KR940005582B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0216195B1 (de) | 1990-06-13 |
KR870002268A (ko) | 1987-03-30 |
JPH0668B2 (ja) | 1994-01-05 |
EP0216195A1 (de) | 1987-04-01 |
JPS6251993A (ja) | 1987-03-06 |
KR940005582B1 (ko) | 1994-06-21 |
DE3671916D1 (de) | 1990-07-19 |
CA1295564C (en) | 1992-02-11 |
US5059538A (en) | 1991-10-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |