ATE535602T1 - Modifiziertes insulin mit reduzierter immunogenität - Google Patents

Modifiziertes insulin mit reduzierter immunogenität

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Publication number
ATE535602T1
ATE535602T1 AT02736480T AT02736480T ATE535602T1 AT E535602 T1 ATE535602 T1 AT E535602T1 AT 02736480 T AT02736480 T AT 02736480T AT 02736480 T AT02736480 T AT 02736480T AT E535602 T1 ATE535602 T1 AT E535602T1
Authority
AT
Austria
Prior art keywords
reduced immunogenicity
modified insulin
insulin
modified
immunogenicity
Prior art date
Application number
AT02736480T
Other languages
English (en)
Inventor
Pradip Mukerji
Yung-Sheng Huang
Tapas Das
Jennifer Thurmond
Suzette Pereira
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Priority claimed from PCT/US2002/001924 external-priority patent/WO2002081668A2/en
Application granted granted Critical
Publication of ATE535602T1 publication Critical patent/ATE535602T1/de

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    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0083—Miscellaneous (1.14.99)
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    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
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    • C12P7/6409—Fatty acids
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    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
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    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
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  • Veterinary Medicine (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Genetics & Genomics (AREA)
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  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
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  • Nutrition Science (AREA)
AT02736480T 2001-01-25 2002-01-24 Modifiziertes insulin mit reduzierter immunogenität ATE535602T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/769,863 US6635451B2 (en) 2001-01-25 2001-01-25 Desaturase genes and uses thereof
US10/054,534 US7067285B2 (en) 2001-01-25 2002-01-22 Desaturase genes and uses thereof
PCT/US2002/001924 WO2002081668A2 (en) 2001-01-25 2002-01-24 Desaturase genes and uses thereof

Publications (1)

Publication Number Publication Date
ATE535602T1 true ATE535602T1 (de) 2011-12-15

Family

ID=27735000

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02736480T ATE535602T1 (de) 2001-01-25 2002-01-24 Modifiziertes insulin mit reduzierter immunogenität

Country Status (8)

Country Link
US (6) US6635451B2 (de)
EP (2) EP2333052B1 (de)
JP (3) JP4347397B2 (de)
AR (1) AR035534A1 (de)
AT (1) ATE535602T1 (de)
CA (2) CA2698579C (de)
ES (1) ES2377198T3 (de)
PT (1) PT1392823E (de)

Families Citing this family (34)

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US6635451B2 (en) * 2001-01-25 2003-10-21 Abbott Laboratories Desaturase genes and uses thereof
US20050089879A1 (en) * 2001-07-31 2005-04-28 Ivo Feussner Method for producing arachidonic acid in transgenic organisms
DE10219203A1 (de) * 2002-04-29 2003-11-13 Basf Plant Science Gmbh Verfahren zur Herstellung mehrfach ungesättigter Fettsäuren in Pflanzen
EP1619960A4 (de) * 2003-03-07 2009-03-18 Advanced Bionutrition Corp Futtermittelformulierung für land- und wasserbewohner
DE602004021001D1 (de) 2003-08-21 2009-06-18 Monsanto Technology Llc Fettsäuredesaturasen aus primula
WO2005102310A1 (en) 2004-04-16 2005-11-03 Monsanto Technology Llc Expression of fatty acid desaturases in corn
AU2011232757B2 (en) * 2004-04-22 2013-10-03 Commonwealth Scientific And Industrial Research Organisation Synthesis of long-chain polyunsaturated fatty acids by recombinant cells
CN102559364B (zh) 2004-04-22 2016-08-17 联邦科学技术研究组织 用重组细胞合成长链多不饱和脂肪酸
EP2363492A3 (de) 2004-04-22 2012-03-14 Commonwealth Scientific and Industrial Research Organisation Synthese von langkettigen polyungesättigten Fettsäuren durch rekombinante Zellen
US7364883B2 (en) * 2004-05-07 2008-04-29 Yeastern Biotech Co., Ltd. Process for producing poly-unsaturated fatty acids by oleaginous yeasts
BRPI0511236A (pt) * 2004-06-04 2007-11-27 Fluxome Sciences As método para a produção de ácidos graxos poliinsaturados com quatro ou mais ligações duplas, saccharomyces cerevisiae geneticamente modificado que tem capacidade de produzir ácidos graxos poliinsaturados com quatro ou mais ligações duplas quando desenvolvido em um substrato que não de ácido graxo, composição, uso da composição e uso de um saccharomyces cervisiae geneticamente modificado
US8685679B2 (en) * 2004-11-04 2014-04-01 E I Du Pont De Nemours And Company Acyltransferase regulation to increase the percent of polyunsaturated fatty acids in total lipids and oils of oleaginous organisms
US7588931B2 (en) * 2004-11-04 2009-09-15 E. I. Du Pont De Nemours And Company High arachidonic acid producing strains of Yarrowia lipolytica
EP1863916B1 (de) * 2005-03-16 2011-08-24 Metabolix, Inc. Chemisch induzierbare Expression von Biosynthesewegen
JP5033122B2 (ja) 2005-05-23 2012-09-26 アルカディア バイオサイエンシズ，インコーポレイテッド 増量ガンマ−リノレン酸を含むベニバナ
PL2447356T3 (pl) 2005-06-07 2016-10-31 Mikroorganizmy eukariotyczne do wytwarzania lipidów i przeciwutleniaczy
EP1991047B1 (de) 2006-03-01 2012-09-26 Pioneer Hi-Bred International Inc. Zusammensetzung in zusammenhang mit dem quantitative trait locus 6 (qtl6) in mais und anwendungsverfahren dafür
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