ATE533756T1 - N-formyl-hydroxylamin-verbindungen - Google Patents

N-formyl-hydroxylamin-verbindungen

Info

Publication number
ATE533756T1
ATE533756T1 AT06770806T AT06770806T ATE533756T1 AT E533756 T1 ATE533756 T1 AT E533756T1 AT 06770806 T AT06770806 T AT 06770806T AT 06770806 T AT06770806 T AT 06770806T AT E533756 T1 ATE533756 T1 AT E533756T1
Authority
AT
Austria
Prior art keywords
hydroxylamin
formyl
compounds
hydroxylamin compounds
formyl hydroxylamin
Prior art date
Application number
AT06770806T
Other languages
English (en)
Inventor
Kathryn Rene Bracken
Simon Bushell
Karl Dean
Charles Francavilla
Rakesh K Jain
Kwangho Lee
Mohindra Seepersaud
Lei Shu
Arathia Sundaram
Zhengyu Yuan
Original Assignee
Novartis Ag
Vicuron Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=37023394&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE533756(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag, Vicuron Pharm Inc filed Critical Novartis Ag
Application granted granted Critical
Publication of ATE533756T1 publication Critical patent/ATE533756T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT06770806T 2005-05-23 2006-05-22 N-formyl-hydroxylamin-verbindungen ATE533756T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US68365505P 2005-05-23 2005-05-23
PCT/US2006/019688 WO2006127576A2 (en) 2005-05-23 2006-05-22 N - formyl hydroxylamine compounds as pdf inhibitors

Publications (1)

Publication Number Publication Date
ATE533756T1 true ATE533756T1 (de) 2011-12-15

Family

ID=37023394

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06770806T ATE533756T1 (de) 2005-05-23 2006-05-22 N-formyl-hydroxylamin-verbindungen

Country Status (17)

Country Link
US (2) US7615635B2 (de)
EP (1) EP1896452B1 (de)
JP (1) JP2008545692A (de)
KR (1) KR20080015411A (de)
CN (1) CN101193882B (de)
AR (1) AR056360A1 (de)
AT (1) ATE533756T1 (de)
AU (1) AU2006251612B2 (de)
BR (1) BRPI0611369A2 (de)
CA (1) CA2608634A1 (de)
GT (1) GT200600196A (de)
MY (1) MY142411A (de)
PE (1) PE20061421A1 (de)
PT (1) PT1896452E (de)
RU (1) RU2412939C2 (de)
TW (1) TW200706534A (de)
WO (1) WO2006127576A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE360014T1 (de) 2001-06-15 2007-05-15 Vicuron Pharm Inc Bicyclische pyrrolidinverbindungen
SG133452A1 (en) * 2005-12-30 2007-07-30 Novartis Ag Peptide deformylase inhibitors for treatment of mycobacterial and other parasitic diseases
TW201716375A (zh) 2007-06-12 2017-05-16 Achaogen Inc 抗菌劑
US7994174B2 (en) * 2007-09-19 2011-08-09 Vertex Pharmaceuticals Incorporated Pyridyl sulfonamides as modulators of ion channels
UA108596C2 (xx) 2007-11-09 2015-05-25 Інгібітори пептиддеформілази
CN102452998B (zh) * 2010-10-20 2014-12-10 天津药物研究院 N-甲酰羟胺类化合物及其制备方法和用途
CN103159660B (zh) * 2011-12-08 2016-07-06 天津市国际生物医药联合研究院 (2r)-1-(2-甲基-3-(甲氧基(甲基)氨基)-丙酰基)吡咯烷-2-羧酸及其应用
EP2847168A1 (de) 2012-05-10 2015-03-18 Achaogen, Inc. Antibakterielle wirkstoffe
JP2016504348A (ja) * 2012-12-26 2016-02-12 ワンブリー リミテッド 置換オキサゾリジノンのアルデヒド誘導体
US10738028B2 (en) 2016-05-11 2020-08-11 Rudong Ruien Pharmaceutical Technology Co. Ltd Spiro three-membered ring, spiro five-membered ring peptide deformylase inhibitor and use thereof in antibacteria and anti-tumor

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2320476A1 (en) 1998-02-07 1999-08-12 British Biotech Pharmaceuticals Limited Antibacterial agents
GB9802549D0 (en) * 1998-02-07 1998-04-01 British Biotech Pharm Antibacterial agents
US6852752B2 (en) * 1999-12-17 2005-02-08 Vicuron Pharmaceuticals Inc. Urea compounds, compositions and methods of use and preparation
US6797820B2 (en) * 1999-12-17 2004-09-28 Vicuron Pharmaceuticals Inc. Succinate compounds, compositions and methods of use and preparation
ATE360014T1 (de) * 2001-06-15 2007-05-15 Vicuron Pharm Inc Bicyclische pyrrolidinverbindungen
AR036053A1 (es) * 2001-06-15 2004-08-04 Versicor Inc Compuestos de n-formil-hidroxilamina, un proceso para su preparacion y composiciones farmaceuticas
KR20050057429A (ko) * 2002-09-19 2005-06-16 노파르티스 아게 중간체의 제조 방법
AU2004216178B2 (en) * 2003-02-21 2008-07-03 Novartis Ag Chemical process for the preparation of intermediates to obtain N-formyl hydroxylamine compounds
TW200427458A (en) * 2003-04-02 2004-12-16 Novartis Ag Crystalline N-formyl hydroxylamine compounds
JP2009513485A (ja) * 2003-06-26 2009-04-02 ノバルティス アクチエンゲゼルシャフト ある種の抗菌性ｎ−ホルミルヒドロキシルアミン化合物の製造に有用な中間体の製造法

Also Published As

Publication number Publication date
JP2008545692A (ja) 2008-12-18
TW200706534A (en) 2007-02-16
US20100063278A1 (en) 2010-03-11
KR20080015411A (ko) 2008-02-19
WO2006127576A2 (en) 2006-11-30
US7615635B2 (en) 2009-11-10
GT200600196A (es) 2007-01-15
CN101193882B (zh) 2011-09-07
PE20061421A1 (es) 2007-01-22
AU2006251612B2 (en) 2010-05-20
RU2412939C2 (ru) 2011-02-27
WO2006127576A3 (en) 2007-01-25
BRPI0611369A2 (pt) 2010-08-31
AR056360A1 (es) 2007-10-03
AU2006251612A1 (en) 2006-11-30
US20080161558A1 (en) 2008-07-03
PT1896452E (pt) 2012-02-15
EP1896452B1 (de) 2011-11-16
RU2007147433A (ru) 2009-06-27
CN101193882A (zh) 2008-06-04
EP1896452A2 (de) 2008-03-12
MY142411A (en) 2010-11-30
US8044199B2 (en) 2011-10-25
CA2608634A1 (en) 2006-11-30

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