ATE525469T1 - Nachweis kleiner nukleinsäuren - Google Patents
Nachweis kleiner nukleinsäurenInfo
- Publication number
- ATE525469T1 ATE525469T1 AT03813850T AT03813850T ATE525469T1 AT E525469 T1 ATE525469 T1 AT E525469T1 AT 03813850 T AT03813850 T AT 03813850T AT 03813850 T AT03813850 T AT 03813850T AT E525469 T1 ATE525469 T1 AT E525469T1
- Authority
- AT
- Austria
- Prior art keywords
- detection
- present
- nucleic acids
- methods
- mirnas
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
- C12Q1/6818—Hybridisation assays characterised by the detection means involving interaction of two or more labels, e.g. resonant energy transfer
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43451802P | 2002-12-18 | 2002-12-18 | |
PCT/US2003/041549 WO2004057017A2 (en) | 2002-12-18 | 2003-12-18 | Detection of small nucleic acids |
US10/740,256 US7851150B2 (en) | 2002-12-18 | 2003-12-18 | Detection of small nucleic acids |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE525469T1 true ATE525469T1 (de) | 2011-10-15 |
Family
ID=32685318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03813850T ATE525469T1 (de) | 2002-12-18 | 2003-12-18 | Nachweis kleiner nukleinsäuren |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP2361991A1 (de) |
JP (1) | JP4230457B2 (de) |
AT (1) | ATE525469T1 (de) |
AU (1) | AU2003297541A1 (de) |
CA (1) | CA2510381C (de) |
HK (1) | HK1083111A1 (de) |
MX (1) | MXPA05006633A (de) |
NO (1) | NO20053465L (de) |
WO (1) | WO2004057017A2 (de) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040219565A1 (en) | 2002-10-21 | 2004-11-04 | Sakari Kauppinen | Oligonucleotides useful for detecting and analyzing nucleic acids of interest |
AU2003291433B2 (en) | 2002-11-13 | 2008-05-22 | Thomas Jefferson University | Compositions and methods for cancer diagnosis and therapy |
US8206904B2 (en) | 2002-12-18 | 2012-06-26 | Third Wave Technologies, Inc. | Detection of nucleic acids |
US7683036B2 (en) | 2003-07-31 | 2010-03-23 | Regulus Therapeutics Inc. | Oligomeric compounds and compositions for use in modulation of small non-coding RNAs |
CA2539654A1 (en) * | 2003-10-14 | 2005-05-06 | Novartis Ag | Oligonucleotide microarray |
JP5192229B2 (ja) * | 2004-04-07 | 2013-05-08 | エクシコン・アクティーゼルスカブ | microRNAおよび低分子干渉RNAの定量化のための新規方法 |
US8192937B2 (en) | 2004-04-07 | 2012-06-05 | Exiqon A/S | Methods for quantification of microRNAs and small interfering RNAs |
WO2006033020A2 (en) * | 2004-04-26 | 2006-03-30 | Rosetta Genomics Ltd. | Methods and apparatus for the detection and validation of micrornas |
EP1784501B1 (de) | 2004-05-14 | 2015-11-18 | Rosetta Genomics Ltd | Micro-rnas und deren verwendung |
US7795419B2 (en) | 2004-05-26 | 2010-09-14 | Rosetta Genomics Ltd. | Viral and viral associated miRNAs and uses thereof |
AU2005250432B2 (en) | 2004-05-28 | 2011-09-15 | Asuragen, Inc. | Methods and compositions involving microRNA |
US7575863B2 (en) | 2004-05-28 | 2009-08-18 | Applied Biosystems, Llc | Methods, compositions, and kits comprising linker probes for quantifying polynucleotides |
US20060057595A1 (en) * | 2004-09-16 | 2006-03-16 | Applera Corporation | Compositions, methods, and kits for identifying and quantitating small RNA molecules |
ES2534304T3 (es) | 2004-11-12 | 2015-04-21 | Asuragen, Inc. | Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN |
WO2006078042A1 (ja) * | 2005-01-20 | 2006-07-27 | Kurume University | 小分子rnaの検出方法および小分子rna検出用試薬 |
JP2006292367A (ja) * | 2005-04-05 | 2006-10-26 | Mitsubishi Rayon Co Ltd | miRNA検出用マイクロアレイ |
WO2006135765A1 (en) * | 2005-06-09 | 2006-12-21 | Epoch Biosciences, Inc. | Improved primer-based amplification methods |
ATE491045T1 (de) | 2005-06-23 | 2010-12-15 | Keygene Nv | Strategien mit hohem durchsatz zur identifizierung und zum nachweis von polymorphismen |
US10316364B2 (en) | 2005-09-29 | 2019-06-11 | Keygene N.V. | Method for identifying the source of an amplicon |
JP5237099B2 (ja) | 2005-09-29 | 2013-07-17 | キージーン ナムローゼ フェンノートシャップ | 変異させた集団のハイスループットスクリーニング |
WO2007073165A1 (en) | 2005-12-22 | 2007-06-28 | Keygene N.V. | Method for high-throughput aflp-based polymorphism detection |
JP4989493B2 (ja) * | 2006-01-20 | 2012-08-01 | オリンパス株式会社 | 分子内プローブによる核酸配列の検出方法 |
ES2545264T3 (es) | 2006-04-04 | 2015-09-09 | Keygene N.V. | Detección de alto rendimiento de marcadores moleculares basada en fragmentos de restricción |
CN101541975B (zh) * | 2006-06-01 | 2013-04-03 | 第三次浪潮技术公司 | 核酸的检测 |
US8445238B2 (en) | 2006-10-04 | 2013-05-21 | Third Wave Technologies, Inc. | Snap-back primers and detectable hairpin structures |
US8361714B2 (en) | 2007-09-14 | 2013-01-29 | Asuragen, Inc. | Micrornas differentially expressed in cervical cancer and uses thereof |
EP2285960B1 (de) | 2008-05-08 | 2015-07-08 | Asuragen, INC. | Zusammensetzungen und verfahren in zusammenhang mit der mirna-184modulation von neovaskularisation oder angiogenese |
JP5322066B2 (ja) | 2008-07-03 | 2013-10-23 | 国立大学法人神戸大学 | 関節リウマチ関連マイクロrna |
US9644241B2 (en) | 2011-09-13 | 2017-05-09 | Interpace Diagnostics, Llc | Methods and compositions involving miR-135B for distinguishing pancreatic cancer from benign pancreatic disease |
GB2520763A (en) | 2013-12-02 | 2015-06-03 | Vanadis Diagnostics Ab | Nucleic acid probe and method of detecting genomic fragments |
JP6688318B2 (ja) * | 2015-05-01 | 2020-04-28 | ジェン−プローブ・インコーポレーテッド | 多重侵入切断アッセイ |
BR112018001686A2 (pt) | 2015-09-18 | 2018-09-18 | Vanadis Diagnostics | conjunto de sonda para analisar uma amostra de dna e método para usar o mesmo |
EP3668998A1 (de) | 2017-10-06 | 2020-06-24 | Cartana AB | Rna-template-ligation |
JP2024000312A (ja) * | 2022-06-20 | 2024-01-05 | Toppanホールディングス株式会社 | 蛍光物質及び消光物質で標識された一本鎖オリゴヌクレオチド |
WO2023248568A1 (ja) * | 2022-06-20 | 2023-12-28 | Toppanホールディングス株式会社 | 蛍光を検出するための方法 |
Family Cites Families (55)
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US5288609A (en) | 1984-04-27 | 1994-02-22 | Enzo Diagnostics, Inc. | Capture sandwich hybridization method and composition |
US5011769A (en) | 1985-12-05 | 1991-04-30 | Meiogenics U.S. Limited Partnership | Methods for detecting nucleic acid sequences |
US5124246A (en) | 1987-10-15 | 1992-06-23 | Chiron Corporation | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
US5359100A (en) | 1987-10-15 | 1994-10-25 | Chiron Corporation | Bifunctional blocked phosphoramidites useful in making nucleic acid mutimers |
US5403711A (en) | 1987-11-30 | 1995-04-04 | University Of Iowa Research Foundation | Nucleic acid hybridization and amplification method for detection of specific sequences in which a complementary labeled nucleic acid probe is cleaved |
CA1340807C (en) | 1988-02-24 | 1999-11-02 | Lawrence T. Malek | Nucleic acid amplification process |
US5925525A (en) | 1989-06-07 | 1999-07-20 | Affymetrix, Inc. | Method of identifying nucleotide differences |
US5849481A (en) | 1990-07-27 | 1998-12-15 | Chiron Corporation | Nucleic acid hybridization assays employing large comb-type branched polynucleotides |
US5432272A (en) | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
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US7150982B2 (en) | 1991-09-09 | 2006-12-19 | Third Wave Technologies, Inc. | RNA detection assays |
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US6017696A (en) | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
US5541311A (en) | 1992-12-07 | 1996-07-30 | Third Wave Technologies, Inc. | Nucleic acid encoding synthesis-deficient thermostable DNA polymerase |
US5614402A (en) | 1992-12-07 | 1997-03-25 | Third Wave Technologies, Inc. | 5' nucleases derived from thermostable DNA polymerase |
US6096880A (en) * | 1993-04-15 | 2000-08-01 | University Of Rochester | Circular DNA vectors for synthesis of RNA and DNA |
US5858659A (en) | 1995-11-29 | 1999-01-12 | Affymetrix, Inc. | Polymorphism detection |
US6045996A (en) | 1993-10-26 | 2000-04-04 | Affymetrix, Inc. | Hybridization assays on oligonucleotide arrays |
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US5851770A (en) | 1994-04-25 | 1998-12-22 | Variagenics, Inc. | Detection of mismatches by resolvase cleavage using a magnetic bead support |
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EP1260593A3 (de) | 1994-12-23 | 2003-12-03 | Dade Behring Inc. | Nachweis von Nukleinsäuren durch Nuklease-katalysierte Produktbildung |
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JP2004521606A (ja) | 2000-05-24 | 2004-07-22 | サード・ウェーブ・テクノロジーズ・インク | Rnaの検出法 |
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GB0212995D0 (en) | 2002-06-06 | 2002-07-17 | Unilever Plc | Ligand and complex for catalytically bleaching a substrate |
JPWO2010084839A1 (ja) | 2009-01-26 | 2012-07-19 | 日本電気株式会社 | 尤度推定装置、コンテンツ配信システム、尤度推定方法および尤度推定プログラム |
-
2003
- 2003-12-18 AT AT03813850T patent/ATE525469T1/de not_active IP Right Cessation
- 2003-12-18 MX MXPA05006633A patent/MXPA05006633A/es active IP Right Grant
- 2003-12-18 EP EP10179311A patent/EP2361991A1/de not_active Withdrawn
- 2003-12-18 JP JP2004561463A patent/JP4230457B2/ja not_active Expired - Lifetime
- 2003-12-18 CA CA2510381A patent/CA2510381C/en not_active Expired - Lifetime
- 2003-12-18 EP EP03813850A patent/EP1573009B1/de not_active Expired - Lifetime
- 2003-12-18 AU AU2003297541A patent/AU2003297541A1/en not_active Abandoned
- 2003-12-18 WO PCT/US2003/041549 patent/WO2004057017A2/en active Application Filing
-
2005
- 2005-07-15 NO NO20053465A patent/NO20053465L/no not_active Application Discontinuation
-
2006
- 2006-03-09 HK HK06103073.8A patent/HK1083111A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2510381A1 (en) | 2004-07-08 |
NO20053465L (no) | 2005-09-13 |
WO2004057017A2 (en) | 2004-07-08 |
CA2510381C (en) | 2014-07-08 |
JP4230457B2 (ja) | 2009-02-25 |
HK1083111A1 (en) | 2006-06-23 |
NO20053465D0 (no) | 2005-07-15 |
EP1573009A2 (de) | 2005-09-14 |
JP2006510372A (ja) | 2006-03-30 |
MXPA05006633A (es) | 2006-05-25 |
EP2361991A1 (de) | 2011-08-31 |
EP1573009B1 (de) | 2011-09-21 |
WO2004057017A3 (en) | 2005-03-10 |
EP1573009A4 (de) | 2006-07-12 |
AU2003297541A1 (en) | 2004-07-14 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |