ATE525093T1 - Modelle für die bewertung von impfstoffen - Google Patents

Modelle für die bewertung von impfstoffen

Info

Publication number
ATE525093T1
ATE525093T1 AT07872536T AT07872536T ATE525093T1 AT E525093 T1 ATE525093 T1 AT E525093T1 AT 07872536 T AT07872536 T AT 07872536T AT 07872536 T AT07872536 T AT 07872536T AT E525093 T1 ATE525093 T1 AT E525093T1
Authority
AT
Austria
Prior art keywords
models
vaccine evaluation
vaccine
evaluation
population
Prior art date
Application number
AT07872536T
Other languages
English (en)
Inventor
John Tew
Shikh Mohey El
Inderpal Singh
Eric Mishkin
Donald Drake
Haifeng Song
William Warren
Original Assignee
Sanofi Pasteur Vaxdesign Corp
Univ Virginia Commonwealth
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Vaxdesign Corp, Univ Virginia Commonwealth filed Critical Sanofi Pasteur Vaxdesign Corp
Application granted granted Critical
Publication of ATE525093T1 publication Critical patent/ATE525093T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0337—Animal models for infectious diseases
AT07872536T 2006-06-27 2007-06-27 Modelle für die bewertung von impfstoffen ATE525093T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81663706P 2006-06-27 2006-06-27
PCT/US2007/014826 WO2008094178A2 (en) 2006-06-27 2007-06-27 Models for vaccine assessment

Publications (1)

Publication Number Publication Date
ATE525093T1 true ATE525093T1 (de) 2011-10-15

Family

ID=39674632

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07872536T ATE525093T1 (de) 2006-06-27 2007-06-27 Modelle für die bewertung von impfstoffen

Country Status (6)

Country Link
US (2) US7709257B2 (de)
EP (3) EP2043695B8 (de)
AT (1) ATE525093T1 (de)
AU (1) AU2007345747A1 (de)
CA (1) CA2655344C (de)
WO (1) WO2008094178A2 (de)

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US7709256B2 (en) * 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
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EP2761008A1 (de) 2011-09-26 2014-08-06 Kymab Limited Chimäre surrogatleichtketten (slc) mit humanem vpreb
US9253965B2 (en) 2012-03-28 2016-02-09 Kymab Limited Animal models and therapeutic molecules
EP2822578A4 (de) * 2012-03-07 2015-10-07 Childrens Medical Center Gewebekonstrukte und verwendungen davon
US10251377B2 (en) 2012-03-28 2019-04-09 Kymab Limited Transgenic non-human vertebrate for the expression of class-switched, fully human, antibodies
GB2502127A (en) 2012-05-17 2013-11-20 Kymab Ltd Multivalent antibodies and in vivo methods for their production
US9788534B2 (en) 2013-03-18 2017-10-17 Kymab Limited Animal models and therapeutic molecules
US9783618B2 (en) 2013-05-01 2017-10-10 Kymab Limited Manipulation of immunoglobulin gene diversity and multi-antibody therapeutics
US11707056B2 (en) 2013-05-02 2023-07-25 Kymab Limited Animals, repertoires and methods
US9783593B2 (en) 2013-05-02 2017-10-10 Kymab Limited Antibodies, variable domains and chains tailored for human use
SG11201602236SA (en) 2013-10-01 2016-04-28 Kymab Ltd Animal models and therapeutic molecules

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US7771999B2 (en) * 2004-04-28 2010-08-10 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US7709256B2 (en) * 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US7785806B2 (en) * 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
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AU2006331504A1 (en) * 2005-12-21 2007-07-05 Vaxdesign Corporation In vitro germinal centers
ATE495238T1 (de) * 2005-12-21 2011-01-15 Vaxdesign Corp Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen
EP2043695B8 (de) 2006-06-27 2012-02-29 Sanofi Pasteur VaxDesign Corporation Modelle für die bewertung von impfstoffen
AU2008275296A1 (en) * 2007-07-06 2009-01-15 Sanofi Pasteur Vaxdesign Corporation Rapid generation of T cell-independent antibody responses to T cell-dependent antigens

Also Published As

Publication number Publication date
EP2043695B8 (de) 2012-02-29
US20080008653A1 (en) 2008-01-10
AU2007345747A1 (en) 2008-08-07
CA2655344A1 (en) 2008-08-07
WO2008094178A2 (en) 2008-08-07
EP2043695A2 (de) 2009-04-08
WO2008094178A9 (en) 2008-10-02
US7709257B2 (en) 2010-05-04
EP2409715A1 (de) 2012-01-25
EP2043695B1 (de) 2011-09-21
EP2409714A1 (de) 2012-01-25
US20100287630A1 (en) 2010-11-11
CA2655344C (en) 2016-09-13
WO2008094178A3 (en) 2009-02-12

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