ATE521707T1 - Derivate eines nf-kappab induzierenden enzyms, verfahren zur herstellung der derivate und deren verwendung - Google Patents
Derivate eines nf-kappab induzierenden enzyms, verfahren zur herstellung der derivate und deren verwendungInfo
- Publication number
- ATE521707T1 ATE521707T1 AT03746399T AT03746399T ATE521707T1 AT E521707 T1 ATE521707 T1 AT E521707T1 AT 03746399 T AT03746399 T AT 03746399T AT 03746399 T AT03746399 T AT 03746399T AT E521707 T1 ATE521707 T1 AT E521707T1
- Authority
- AT
- Austria
- Prior art keywords
- derivatives
- kappab
- producing
- inducing enzyme
- inducing
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
- C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/022—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from an adenovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pulmonology (AREA)
- Neurology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL14921702A IL149217A0 (en) | 2002-04-18 | 2002-04-18 | Derivatives of the il-2 receptor gamma chain, their preparation and use |
IL15218302A IL152183A0 (en) | 2002-10-08 | 2002-10-08 | Derivatives of the il-2 receptor gamma chain, their preparation and use |
PCT/IL2003/000317 WO2003087380A1 (en) | 2002-04-18 | 2003-04-15 | Derivatives of the nf-kappab inducing enzyme, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE521707T1 true ATE521707T1 (de) | 2011-09-15 |
Family
ID=29252551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT03746399T ATE521707T1 (de) | 2002-04-18 | 2003-04-15 | Derivate eines nf-kappab induzierenden enzyms, verfahren zur herstellung der derivate und deren verwendung |
Country Status (13)
Country | Link |
---|---|
US (3) | US8330026B2 (de) |
EP (2) | EP1499724B1 (de) |
JP (2) | JP4435575B2 (de) |
AR (2) | AR039645A1 (de) |
AT (1) | ATE521707T1 (de) |
AU (2) | AU2003222415B2 (de) |
CA (2) | CA2482387C (de) |
CY (1) | CY1111864T1 (de) |
DK (1) | DK1499729T5 (de) |
ES (1) | ES2415331T3 (de) |
PT (1) | PT1499729E (de) |
SI (1) | SI1499729T1 (de) |
WO (2) | WO2003087374A1 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL158287A0 (en) * | 2003-10-07 | 2004-05-12 | Yeda Res & Dev | Antibodies to nik, their preparation and use |
CA2547459C (en) * | 2003-11-30 | 2013-10-08 | Yeda Research And Development Co. Ltd | Modulators of nik-siva complex formation for treating immune disorders |
US8034773B2 (en) * | 2004-02-05 | 2011-10-11 | Arizona Biomedical Research Commission | Immunostimulatory compositions and uses thereof |
IL166006A0 (en) * | 2004-12-27 | 2006-01-15 | Yeda Res & Dev | Pharmaceutical compositions for treating diseases associated with nf-kb activity |
US8663309B2 (en) | 2007-09-26 | 2014-03-04 | Trivascular, Inc. | Asymmetric stent apparatus and method |
US8226701B2 (en) | 2007-09-26 | 2012-07-24 | Trivascular, Inc. | Stent and delivery system for deployment thereof |
US8066755B2 (en) | 2007-09-26 | 2011-11-29 | Trivascular, Inc. | System and method of pivoted stent deployment |
BRPI0817488A2 (pt) * | 2007-10-04 | 2017-05-16 | Trivascular Inc | enxerto vascular modular para perfil percutâneo baixo |
US8328861B2 (en) | 2007-11-16 | 2012-12-11 | Trivascular, Inc. | Delivery system and method for bifurcated graft |
US8083789B2 (en) | 2007-11-16 | 2011-12-27 | Trivascular, Inc. | Securement assembly and method for expandable endovascular device |
US8992595B2 (en) | 2012-04-04 | 2015-03-31 | Trivascular, Inc. | Durable stent graft with tapered struts and stable delivery methods and devices |
US9498363B2 (en) | 2012-04-06 | 2016-11-22 | Trivascular, Inc. | Delivery catheter for endovascular device |
JP6234446B2 (ja) * | 2012-06-08 | 2017-11-22 | アルカーメス,インコーポレイテッド | ムチンドメインポリペプチドに連結された活性タンパク質を含む融合ポリペプチド |
US20200009266A1 (en) * | 2017-02-15 | 2020-01-09 | Fred Hutchinson Cancer Research Center | In vivo gene therapy for immune deficiencies |
EP3609519A4 (de) * | 2017-04-11 | 2021-03-31 | University of Maryland, Baltimore | Zusammensetzungen und verfahren zur behandlung von entzündungen und krebs |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US510259A (en) * | 1893-12-05 | Pavement | ||
US5194596A (en) * | 1989-07-27 | 1993-03-16 | California Biotechnology Inc. | Production of vascular endothelial cell growth factor |
US5350836A (en) * | 1989-10-12 | 1994-09-27 | Ohio University | Growth hormone antagonists |
JP3255699B2 (ja) * | 1992-04-23 | 2002-02-12 | 味の素株式会社 | ヒトIL−2レセプターγ鎖分子 |
US7070972B1 (en) * | 1995-01-13 | 2006-07-04 | The United States Of America As Represented By The Department Of Health And Human Services | Janus family kinases and identification of immune modulators |
UA71889C2 (uk) | 1996-04-02 | 2005-01-17 | Йєда Рісерч Енд Дівелопмент Ко. Лтд. | Модулятори зв'язаного з рецептором tnf фактора (traf), їх одержання та застосування |
EP1500329B1 (de) | 1996-12-03 | 2012-03-21 | Amgen Fremont Inc. | Menschliche Antikörper, die ausdrücklich menschliches TNF Alpha binden |
US5843721A (en) | 1997-07-03 | 1998-12-01 | Tularik Inc. | Nucleic acids encoding human NIK protein |
AU781292B2 (en) | 1999-03-04 | 2005-05-12 | Praecis Pharmaceuticals Incorporated | Modulators of beta-amyloid peptide aggregation comprising D-amino acids |
-
2003
- 2003-04-15 CA CA2482387A patent/CA2482387C/en not_active Expired - Fee Related
- 2003-04-15 AU AU2003222415A patent/AU2003222415B2/en not_active Ceased
- 2003-04-15 WO PCT/IL2003/000316 patent/WO2003087374A1/en active Application Filing
- 2003-04-15 US US10/511,314 patent/US8330026B2/en not_active Expired - Fee Related
- 2003-04-15 JP JP2003584319A patent/JP4435575B2/ja not_active Expired - Fee Related
- 2003-04-15 EP EP03717504.9A patent/EP1499724B1/de not_active Expired - Lifetime
- 2003-04-15 PT PT03746399T patent/PT1499729E/pt unknown
- 2003-04-15 SI SI200332055T patent/SI1499729T1/sl unknown
- 2003-04-15 US US10/511,722 patent/US7416730B2/en not_active Expired - Fee Related
- 2003-04-15 AT AT03746399T patent/ATE521707T1/de active
- 2003-04-15 ES ES03717504T patent/ES2415331T3/es not_active Expired - Lifetime
- 2003-04-15 WO PCT/IL2003/000317 patent/WO2003087380A1/en active Application Filing
- 2003-04-15 EP EP03746399A patent/EP1499729B9/de not_active Expired - Lifetime
- 2003-04-15 AU AU2003226607A patent/AU2003226607C1/en not_active Ceased
- 2003-04-15 CA CA2482718A patent/CA2482718C/en not_active Expired - Fee Related
- 2003-04-15 DK DK03746399.9T patent/DK1499729T5/da active
- 2003-04-15 JP JP2003584315A patent/JP4435574B2/ja not_active Expired - Fee Related
- 2003-04-21 AR ARP030101363A patent/AR039645A1/es not_active Application Discontinuation
- 2003-04-21 AR ARP030101364A patent/AR039646A1/es not_active Application Discontinuation
-
2008
- 2008-07-01 US US12/166,110 patent/US8048847B2/en not_active Expired - Fee Related
-
2011
- 2011-09-27 CY CY20111100934T patent/CY1111864T1/el unknown
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