ATE520704T1 - Peptide für die behandlung von mit dem humanen papillomavirus (hpv) assoziiertem krebs und anderen epitheltumoren - Google Patents

Peptide für die behandlung von mit dem humanen papillomavirus (hpv) assoziiertem krebs und anderen epitheltumoren

Info

Publication number
ATE520704T1
ATE520704T1 AT02796490T AT02796490T ATE520704T1 AT E520704 T1 ATE520704 T1 AT E520704T1 AT 02796490 T AT02796490 T AT 02796490T AT 02796490 T AT02796490 T AT 02796490T AT E520704 T1 ATE520704 T1 AT E520704T1
Authority
AT
Austria
Prior art keywords
hpv
peptides
treatment
human papillomavirus
associated cancer
Prior art date
Application number
AT02796490T
Other languages
English (en)
Inventor
Rodriguez Silvio Ernesto Perea
Acosta Osvaldo Reyes
Vispo Nelson Francisco Santiago
Izaguirre Yaquelin Puchades
Rodriguez Ricardo Silva
Soria Alejandro Moro
Savio Alicia Santos
Lopez Luis Javier Gonzalez
Barrios Belkis Gonzalez
Original Assignee
Ct Ingenieria Genetica Biotech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Ingenieria Genetica Biotech filed Critical Ct Ingenieria Genetica Biotech
Application granted granted Critical
Publication of ATE520704T1 publication Critical patent/ATE520704T1/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/005Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/10Fusion polypeptide containing a localisation/targetting motif containing a tag for extracellular membrane crossing, e.g. TAT or VP22
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011Details
    • C12N2710/20011Papillomaviridae
    • C12N2710/20032Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
AT02796490T 2001-12-20 2002-12-04 Peptide für die behandlung von mit dem humanen papillomavirus (hpv) assoziiertem krebs und anderen epitheltumoren ATE520704T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CU20010309A CU23225A1 (es) 2001-12-20 2001-12-20 PéPTIDOS PARA EL TRATAMIENTO DEL CáNCER ASOCIADO AL VIRUS PAPILOMA HUMANO (VPH) Y DE OTROS TUMORES EPITELIALES
PCT/CU2002/000010 WO2003054002A1 (es) 2001-12-20 2002-12-04 Péptidos para el tratamiento del cáncer asociado al virus papiloma humano (vph) y de otros tumores epiteliales

Publications (1)

Publication Number Publication Date
ATE520704T1 true ATE520704T1 (de) 2011-09-15

Family

ID=40091679

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02796490T ATE520704T1 (de) 2001-12-20 2002-12-04 Peptide für die behandlung von mit dem humanen papillomavirus (hpv) assoziiertem krebs und anderen epitheltumoren

Country Status (34)

Country Link
US (2) US7374767B2 (de)
EP (2) EP1491553B1 (de)
JP (1) JP4056476B2 (de)
KR (1) KR100642437B1 (de)
CN (1) CN100368431C (de)
AR (1) AR037825A1 (de)
AT (1) ATE520704T1 (de)
AU (1) AU2002361922B2 (de)
BR (1) BRPI0215213C1 (de)
CA (1) CA2471110C (de)
CR (1) CR7361A (de)
CU (1) CU23225A1 (de)
DK (1) DK1491553T3 (de)
DO (1) DOP2002000548A (de)
ES (1) ES2371239T3 (de)
HK (1) HK1068901A1 (de)
HN (1) HN2002000377A (de)
HR (1) HRP20040663B1 (de)
IL (2) IL162633A0 (de)
IS (1) IS2906B (de)
MA (1) MA27868A1 (de)
MX (1) MXPA04005832A (de)
MY (1) MY133530A (de)
NO (1) NO333259B1 (de)
NZ (1) NZ534170A (de)
PE (1) PE20030861A1 (de)
PT (1) PT1491553E (de)
RU (1) RU2290410C2 (de)
SI (1) SI1491553T1 (de)
TN (1) TNSN04114A1 (de)
UA (1) UA81403C2 (de)
UY (1) UY27602A1 (de)
WO (1) WO2003054002A1 (de)
ZA (1) ZA200405514B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CU23225A1 (es) * 2001-12-20 2007-08-30 Ct Ingenieria Genetica Biotech PéPTIDOS PARA EL TRATAMIENTO DEL CáNCER ASOCIADO AL VIRUS PAPILOMA HUMANO (VPH) Y DE OTROS TUMORES EPITELIALES
CU23431B6 (es) * 2005-05-12 2009-10-16 Ct Ingenieria Genetica Biotech Método para la inhibición de la proliferación de células tumorales y el tratamiento del cáncer
GB2433740A (en) * 2005-12-23 2007-07-04 Rapid Biosensor Systems Ltd Detection of tuberculosis infection
CU23511B6 (es) * 2006-02-28 2010-04-13 Biorec B V Combinación farmacéutica para el tratamiento y/o quimiosensibilización de tumores refractarios a drogas anticancerígenas
GB2441131A (en) * 2006-08-24 2008-02-27 Univ Dundee Modulation of binding of CK2a to NDPK
CN100522992C (zh) * 2007-02-12 2009-08-05 中国科学院昆明动物研究所 一种环状小肽ba
US20110052725A1 (en) * 2007-03-27 2011-03-03 Takashi Shibata Therapeutic agent for infectious skin and mucosal disease
US20110305706A1 (en) 2009-02-23 2011-12-15 Scott Thomas Brady Compositions and Methods for Treating a Disease Mediated by Soluble Oligomeric Amyloid Beta
CN102625842A (zh) * 2009-03-13 2012-08-01 艾根股份有限公司 用于输送生物活性rna的组合物和方法
EP3397276A4 (de) 2015-12-30 2019-12-18 Kodiak Sciences Inc. Antikörper und konjugate davon
CU20200103A7 (es) * 2020-12-18 2022-07-08 Ct Ingenieria Genetica Biotecnologia Péptido sintético para la inducción de inmunidad antitumoral y antiviral
CU20210058A7 (es) 2021-07-09 2023-02-13 Ct Ingenieria Genetica Biotecnologia Péptidos lineales que inhiben la fosforilación mediada por ck2 y composiciones que los comprenden
CN118370805A (zh) * 2024-04-29 2024-07-23 广州美达康生物医药科技有限公司 一种抑菌妇科凝胶及其制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE902820A1 (en) * 1989-08-07 1991-02-27 Merck & Co Inc Peptide inhibitors of human papilloma virus protein binding¹to retinoblastoma gene proteins
JPH05310784A (ja) * 1991-09-04 1993-11-22 Merck & Co Inc ヒト乳頭腫ウイルスタンパク質と網膜芽細胞腫遺伝子タンパク質との結合のペプチド阻害剤
GB9313556D0 (en) 1993-07-01 1993-08-18 British Tech Group Synthetic peptides of human papillomavirus
US5625031A (en) 1994-02-08 1997-04-29 Bristol-Myers Squibb Company Peptide inhibitors of the p33cdk2 and p34cdc2 cell cycle regulatory kinases and human papillomavirus E7 oncoprotein
ATE235509T1 (de) * 1998-06-30 2003-04-15 Deutsches Krebsforsch Peptide zur inhibition von hpv e7 proteinen
US6641994B2 (en) * 1999-08-25 2003-11-04 Pharmacia & Upjohn Company Methods of identifying anti-viral agents
AU2001238347A1 (en) * 2000-02-28 2001-09-12 Hyseq, Inc. Novel nucleic acids and polypeptides
CU23225A1 (es) * 2001-12-20 2007-08-30 Ct Ingenieria Genetica Biotech PéPTIDOS PARA EL TRATAMIENTO DEL CáNCER ASOCIADO AL VIRUS PAPILOMA HUMANO (VPH) Y DE OTROS TUMORES EPITELIALES

Also Published As

Publication number Publication date
MXPA04005832A (es) 2004-09-13
RU2290410C2 (ru) 2006-12-27
CU23225A1 (es) 2007-08-30
PE20030861A1 (es) 2003-12-02
EP1491553A1 (de) 2004-12-29
ES2371239T3 (es) 2011-12-28
KR100642437B1 (ko) 2006-11-06
BR0215213A (pt) 2004-12-07
EP2383282A1 (de) 2011-11-02
UY27602A1 (es) 2003-04-30
BRPI0215213B1 (pt) 2018-09-11
HRP20040663B1 (hr) 2013-05-31
NZ534170A (en) 2006-08-31
DK1491553T3 (da) 2011-12-05
IL162633A (en) 2011-02-28
AU2002361922A1 (en) 2003-07-09
AU2002361922B2 (en) 2007-04-05
EP1491553B1 (de) 2011-08-17
IS2906B (is) 2014-11-15
IL162633A0 (de) 2005-11-20
IS7320A (is) 2004-06-16
NO333259B1 (no) 2013-04-22
CR7361A (es) 2005-02-18
BRPI0215213C1 (pt) 2021-05-25
CN1620464A (zh) 2005-05-25
RU2004122084A (ru) 2005-03-27
WO2003054002A1 (es) 2003-07-03
MA27868A1 (fr) 2006-05-02
US20060233742A1 (en) 2006-10-19
SI1491553T1 (sl) 2011-12-30
JP4056476B2 (ja) 2008-03-05
AR037825A1 (es) 2004-12-09
HK1068901A1 (en) 2005-05-06
CA2471110C (en) 2017-01-31
JP2005525090A (ja) 2005-08-25
MY133530A (en) 2007-11-30
HRP20040663A2 (en) 2005-08-31
DOP2002000548A (es) 2003-06-30
HN2002000377A (es) 2003-04-10
NO20043112L (no) 2004-07-20
US7947287B2 (en) 2011-05-24
ZA200405514B (en) 2005-03-30
US20090005294A1 (en) 2009-01-01
KR20050002811A (ko) 2005-01-10
CN100368431C (zh) 2008-02-13
UA81403C2 (en) 2008-01-10
CA2471110A1 (en) 2003-07-03
US7374767B2 (en) 2008-05-20
TNSN04114A1 (en) 2006-06-01
PT1491553E (pt) 2011-11-25

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