ATE518893T1 - Festphasenträger für die nukleinsäuresynthese - Google Patents

Festphasenträger für die nukleinsäuresynthese

Info

Publication number
ATE518893T1
ATE518893T1 AT09160705T AT09160705T ATE518893T1 AT E518893 T1 ATE518893 T1 AT E518893T1 AT 09160705 T AT09160705 T AT 09160705T AT 09160705 T AT09160705 T AT 09160705T AT E518893 T1 ATE518893 T1 AT E518893T1
Authority
AT
Austria
Prior art keywords
nucleic acid
phase support
acid synthesis
solid
solid phase
Prior art date
Application number
AT09160705T
Other languages
English (en)
Inventor
Kenjiro Mori
Eri Maeta
Original Assignee
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Application granted granted Critical
Publication of ATE518893T1 publication Critical patent/ATE518893T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/06—Hydrocarbons
    • C08F212/08—Styrene
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F12/02—Monomers containing only one unsaturated aliphatic radical
    • C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
    • C08F12/22—Oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
    • C08F212/22—Oxygen
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F12/00—Homopolymers and copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F12/02—Monomers containing only one unsaturated aliphatic radical
    • C08F12/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F12/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by hetero atoms or groups containing heteroatoms
    • C08F12/16—Halogens
    • C08F12/20—Fluorine
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F212/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an aromatic carbocyclic ring
    • C08F212/02—Monomers containing only one unsaturated aliphatic radical
    • C08F212/04—Monomers containing only one unsaturated aliphatic radical containing one ring
    • C08F212/14—Monomers containing only one unsaturated aliphatic radical containing one ring substituted by heteroatoms or groups containing heteroatoms
    • C08F212/16—Halogens
    • C08F212/20—Fluorine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/25—Web or sheet containing structurally defined element or component and including a second component containing structurally defined particles
    • Y10T428/254—Polymeric or resinous material

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Saccharide Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT09160705T 2008-05-26 2009-05-20 Festphasenträger für die nukleinsäuresynthese ATE518893T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008136468A JP2009280544A (ja) 2008-05-26 2008-05-26 核酸固相合成用担体

Publications (1)

Publication Number Publication Date
ATE518893T1 true ATE518893T1 (de) 2011-08-15

Family

ID=41017188

Family Applications (1)

Application Number Title Priority Date Filing Date
AT09160705T ATE518893T1 (de) 2008-05-26 2009-05-20 Festphasenträger für die nukleinsäuresynthese

Country Status (5)

Country Link
US (1) US20090291294A1 (de)
EP (1) EP2128179B1 (de)
JP (1) JP2009280544A (de)
CN (1) CN101591409B (de)
AT (1) ATE518893T1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5121572B2 (ja) * 2008-05-26 2013-01-16 日東電工株式会社 多孔質重合体粒子の製造方法
EP2666794A1 (de) * 2012-05-23 2013-11-27 Nitto Denko Corporation Festphasenträger für Oligonukleotidsynthese und Oligonukleotidsyntheseverfahren
JP6041685B2 (ja) * 2013-01-24 2016-12-14 日東電工株式会社 核酸合成用固相担体および核酸の合成方法
CN105175772A (zh) * 2015-10-22 2015-12-23 山西科瑞迪生物科技有限公司 多肽/核苷酸合成用固相载体材料易官能化活性树脂的制备方法
CN105175601A (zh) * 2015-10-22 2015-12-23 山西科瑞迪生物科技有限公司 多肽/核苷酸合成用固相载体材料可控孔径活性树脂的制备方法
CN110511973B (zh) * 2019-07-16 2021-05-07 杭州原合生物科技有限公司 一种用于核酸原位合成的固相载体及其制备方法
US20230034857A1 (en) * 2020-09-15 2023-02-02 Lg Chem, Ltd. Microcarrier for cell culture and method for preparing the same
CN115073628B (zh) * 2021-03-15 2023-09-26 中国石油天然气股份有限公司 多孔有机聚合物载体负载的茂金属催化剂体系及其制备方法与应用
CN114874376B (zh) * 2022-06-14 2023-07-11 河北迪纳兴科生物科技有限公司 多孔树脂珠及其制备方法和应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756082A (fr) * 1969-09-12 1971-03-11 I Elementoorganiche Kih Soedin Squelettes macroreticulaires de polystyrene pour resines echangeuses d'ions et leur procede de preparation (
US5047524A (en) 1988-12-21 1991-09-10 Applied Biosystems, Inc. Automated system for polynucleotide synthesis and purification
US5656707A (en) * 1995-06-16 1997-08-12 Regents Of The University Of Minnesota Highly cross-linked polymeric supports
US5668268A (en) * 1995-11-27 1997-09-16 Hybridon, Inc. Passivated polymer supports for nucleic acid synthesis
ES2277178T3 (es) * 2003-08-29 2007-07-01 Nitto Denko Corporation Lecho de resina porosa y metodo para su produccion.
JP4602011B2 (ja) * 2003-08-29 2010-12-22 日東電工株式会社 多孔質樹脂ビーズおよびその製造方法
JP4799831B2 (ja) * 2004-05-14 2011-10-26 日東電工株式会社 多孔質樹脂の製造方法
US7067702B2 (en) * 2004-05-25 2006-06-27 The Johns Hopkins University Process for preparing vinyl substituted beta-diketones
JP4842521B2 (ja) * 2004-06-04 2011-12-21 日東電工株式会社 ビニル系重合体の多孔質球状粒子の製造方法
KR101221186B1 (ko) * 2004-09-02 2013-01-10 닛토덴코 가부시키가이샤 올리고머 합성용 중합체성 비드
JP2006342245A (ja) * 2005-06-08 2006-12-21 Nitto Denko Corp 多孔質樹脂ビーズ
JP4970881B2 (ja) * 2006-09-21 2012-07-11 日東電工株式会社 固相合成用担体
JP5097506B2 (ja) * 2007-11-05 2012-12-12 日東電工株式会社 水酸基を有する多孔質樹脂粒子の製造方法
JP5443682B2 (ja) * 2007-11-05 2014-03-19 日東電工株式会社 ヒドロキシ基又は第１級アミノ基を有する多孔質樹脂粒子とその製造方法
JP5210597B2 (ja) * 2007-11-05 2013-06-12 日東電工株式会社 多孔質樹脂ビーズの製造方法

Also Published As

Publication number Publication date
US20090291294A1 (en) 2009-11-26
CN101591409A (zh) 2009-12-02
CN101591409B (zh) 2012-10-17
EP2128179A1 (de) 2009-12-02
EP2128179B1 (de) 2011-08-03
JP2009280544A (ja) 2009-12-03

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