ATE51522T1 - Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okulartherapeutische mittel. - Google Patents

Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okulartherapeutische mittel.

Info

Publication number
ATE51522T1
ATE51522T1 AT83305184T AT83305184T ATE51522T1 AT E51522 T1 ATE51522 T1 AT E51522T1 AT 83305184 T AT83305184 T AT 83305184T AT 83305184 T AT83305184 T AT 83305184T AT E51522 T1 ATE51522 T1 AT E51522T1
Authority
AT
Austria
Prior art keywords
irritting
formulation
therapeutic agent
aqueous compositions
ophthalmic aqueous
Prior art date
Application number
AT83305184T
Other languages
English (en)
Inventor
Wesley Wehsin Han
Robert Eugene Roehrs
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE51522T1 publication Critical patent/ATE51522T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
AT83305184T 1982-09-07 1983-09-06 Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okulartherapeutische mittel. ATE51522T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/415,758 US4559343A (en) 1982-09-07 1982-09-07 Nonirritating aqueous ophthalmic compositions comfort formulation for ocular therapeutic agents
EP83305184A EP0105635B1 (de) 1982-09-07 1983-09-06 Formulierung nicht irritierender ophthalmischer wässeriger Zusammensetzungen für okular-therapeutische Mittel

Publications (1)

Publication Number Publication Date
ATE51522T1 true ATE51522T1 (de) 1990-04-15

Family

ID=23647073

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83305184T ATE51522T1 (de) 1982-09-07 1983-09-06 Formulierung nicht irritierender ophthalmischer waesseriger zusammensetzungen fuer okulartherapeutische mittel.

Country Status (6)

Country Link
US (1) US4559343A (de)
EP (1) EP0105635B1 (de)
JP (1) JPS5973520A (de)
AT (1) ATE51522T1 (de)
CA (1) CA1217144A (de)
DE (1) DE3381396D1 (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567183A (en) * 1983-03-11 1986-01-28 Analgesic Associates Analgesic and anti-inflammatory compositions comprising xanthines and methods of using same
US4682284A (en) * 1984-12-06 1987-07-21 American Telephone & Telegraph Co., At&T Bell Lab. Queue administration method and apparatus
US4728509A (en) * 1985-08-19 1988-03-01 Takeda Chemical Industries, Ltd. Aqueous liquid preparation
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
US4753945A (en) * 1986-02-19 1988-06-28 Eye Research Institute Of Retina Foundation Stimulation of tear secretion with phosphodiesterase inhibitors
US5171566A (en) * 1986-05-16 1992-12-15 The Green Cross Corporation Flurbiprofen derivative ophthalmic preparation
US4778810A (en) * 1987-01-08 1988-10-18 Nastech Pharmaceutical Co., Inc. Nasal delivery of caffeine
JP2764261B2 (ja) * 1987-03-17 1998-06-11 リ−ドケミカル株式会社 外用消炎鎮痛剤
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
US5110493A (en) * 1987-09-11 1992-05-05 Syntex (U.S.A.) Inc. Ophthalmic NSAID formulations containing a quaternary ammonium preservative and a nonionic surfactant
US4996209A (en) * 1988-06-20 1991-02-26 Alcon Laboratories, Inc. Ophthalmic antiinflammatory compositions comprising S(+)-flurbiprofen
ES2012532A6 (es) * 1988-07-15 1990-04-01 Cusi Lab Un procedimiento para la preparacion de una solucion acuosa de b-metil-4-(2' -tienilcarbonil)fenilacetato de lisina para aplicacion topica oftalmica.
US4960799A (en) * 1988-09-13 1990-10-02 Ciba-Geigy Corporation Stabilized aqueous solutions of pharmaceutically acceptable salts of ortho-(2,6-dichlorophenyl)-aminophenylacetic acid for opthalmic use
US4939135A (en) * 1988-10-03 1990-07-03 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5124392A (en) * 1988-10-03 1992-06-23 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5271939A (en) * 1988-10-03 1993-12-21 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment to prevent and treat corneal scar formation produced by laser irradiation
US5360611A (en) * 1988-10-03 1994-11-01 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following ultraviolet laser irradiation
US5032575A (en) * 1988-10-12 1991-07-16 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5036046A (en) * 1988-10-12 1991-07-30 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds
US5013751A (en) * 1989-01-10 1991-05-07 Alcon Laboratories, Inc. (+) Suprofen esters and amides as opthalmic anti-inflammatory agents
US4988728A (en) * 1989-11-03 1991-01-29 Alcon Laboratories, Inc. Suprofen esters and amides as ophthalmic anti-inflammatory agents
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5444076A (en) * 1990-11-26 1995-08-22 Roemmers S.A.I.C.F. Pharmaceutical preparation for topical application
DE4037554A1 (de) * 1990-11-26 1992-05-27 Roemmers Sa Arzneimittel zur topischen anwendung
US5281353A (en) * 1991-04-24 1994-01-25 Allergan, Inc. Compositions and methods for disinfecting/cleaning of lenses and for destroying oxidative disinfectants
NZ242358A (en) * 1991-05-10 1994-03-25 Allergan Inc Use of thiol compounds to inhibit deposits on a contact lens
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
US5624893A (en) * 1993-10-14 1997-04-29 Alcon Laboratories, Inc. Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
AU684950B2 (en) * 1994-05-06 1998-01-08 Alcon Laboratories, Inc. Use of vitamin E tocopheryl derivatives in ophthalmic compositions
US6309630B1 (en) 1994-05-24 2001-10-30 Insite Vision Incorporated Non-steroidal anti-inflammatory ophthalmic suspensions
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
GB9613457D0 (en) * 1996-06-27 1996-08-28 Procter & Gamble Pharmaceutical compositions
US5814655A (en) * 1996-11-14 1998-09-29 Insite Vision Incorporated Non-steroidal ophthalmic mixtures
US6274592B1 (en) * 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
US6265444B1 (en) 1997-05-23 2001-07-24 Insite Vision Incorporated Ophthalmic composition
AR031135A1 (es) 2000-10-10 2003-09-10 Upjohn Co Composiciones de antibiotico topico para el tratamiento de infecciones oculares
US20030220376A1 (en) * 2001-08-10 2003-11-27 Pharmacia Corporation Methods for treating carbonic anhydrase mediated disorders
BR0307898A (pt) * 2002-02-22 2004-12-07 Pharmacia Corp Formulações de droga antibiótica oftálmica contendo um composto de ciclodextrina e cloreto de cetil piridìnio
US20030191187A1 (en) * 2002-04-01 2003-10-09 Lee Fang Yu Injectable pharmaceutical composition containing a non-steroidal anti-inflammatory drug and method for preparing the same
US20040034042A1 (en) * 2002-08-14 2004-02-19 Masao Tsuji Preservative composition
EP1740168A2 (de) * 2004-04-21 2007-01-10 Advanced Ocular Systems Limited Antiprostaglandine zur behandlung von augenpathologien
US20090092574A1 (en) 2006-12-29 2009-04-09 Scott Richard W Ophthalmic And Otic Compositions Of Facially Amphiphilic Polymers And Oligomers And Uses Thereof
EA201391043A1 (ru) 2011-02-17 2014-03-31 Сентисс Фарма Прайвет Лимитед Способ и композиция для замедления сорбции консервантов пластиками
EP3505154B1 (de) * 2017-12-26 2022-04-06 Industrial Technology Research Institute Zusammensetzung zur verbesserung der löslichkeit schwerlöslicher substanzen, ihre verwendung und diese enthaltende komplexe formulierung

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2994640A (en) * 1957-02-22 1961-08-01 Byk Gulden Lomberg Chem Fab Anti-inflammatory therapy with purine molecular compounds
US3439094A (en) * 1967-07-20 1969-04-15 Warner Lambert Pharmaceutical Analgesic compositions containing namol xenyrate,caffeine and acetyl-rho-aminophenol
DE1911279A1 (de) * 1969-03-05 1970-11-12 Eckert Dr Theodor Verfahren zur Erhoehung der Resorptionsfaehigkeit von Arzneistoffen
US3957994A (en) * 1974-12-19 1976-05-18 Nelson Research & Development Company Topical anti-inflammatory composition and method of use
US4141976A (en) * 1976-01-05 1979-02-27 The Regents Of The University Of Michigan Process for alleviating proliferative skin diseases
NL7707501A (nl) * 1976-08-12 1978-02-14 Knoll Ag Uitwendig toe te dienen geneesmiddelpreparaat.
JPS5697224A (en) * 1979-12-28 1981-08-05 Kaken Pharmaceut Co Ltd Antipyretic analgesic composition
JPS56154416A (en) * 1980-04-30 1981-11-30 Kaken Pharmaceut Co Ltd Antipyretic analgesic composition
JPS59501460A (ja) * 1982-07-22 1984-08-16 サンシヤイン，アブラハム カフェインを含んで成る改良された鎮痛及び抗炎症組成物並びにその使用方法
US4420483A (en) * 1982-07-22 1983-12-13 Richardson-Vicks, Inc. Analgesic and anti-inflammatory compositions comprising ibuprofen and methods of using same

Also Published As

Publication number Publication date
JPS5973520A (ja) 1984-04-25
DE3381396D1 (de) 1990-05-10
EP0105635B1 (de) 1990-04-04
EP0105635A2 (de) 1984-04-18
EP0105635A3 (en) 1986-06-11
CA1217144A (en) 1987-01-27
US4559343A (en) 1985-12-17
JPH0551568B2 (de) 1993-08-03

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Legal Events

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UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee