ATE513820T1 - Neue benzamidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung, die diese enthält - Google Patents

Neue benzamidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung, die diese enthält

Info

Publication number
ATE513820T1
ATE513820T1 AT07708686T AT07708686T ATE513820T1 AT E513820 T1 ATE513820 T1 AT E513820T1 AT 07708686 T AT07708686 T AT 07708686T AT 07708686 T AT07708686 T AT 07708686T AT E513820 T1 ATE513820 T1 AT E513820T1
Authority
AT
Austria
Prior art keywords
pharmaceutical composition
production
composition containing
containing same
benzamidine derivatives
Prior art date
Application number
AT07708686T
Other languages
English (en)
Inventor
Jei Man Ryu
Jin Lee
Young Jin
Ki Young Lee
Jae Hoon Park
Yun Ha Hwang
Sae Kwang Ku
Original Assignee
Dong Wha Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dong Wha Pharm Co Ltd filed Critical Dong Wha Pharm Co Ltd
Application granted granted Critical
Publication of ATE513820T1 publication Critical patent/ATE513820T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
AT07708686T 2006-01-31 2007-01-31 Neue benzamidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung, die diese enthält ATE513820T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20060009459 2006-01-31
PCT/KR2007/000533 WO2007089101A1 (en) 2006-01-31 2007-01-31 Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition comprising the same

Publications (1)

Publication Number Publication Date
ATE513820T1 true ATE513820T1 (de) 2011-07-15

Family

ID=38327631

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07708686T ATE513820T1 (de) 2006-01-31 2007-01-31 Neue benzamidinderivate, verfahren zu deren herstellung und pharmazeutische zusammensetzung, die diese enthält

Country Status (11)

Country Link
US (1) US7943646B2 (de)
EP (1) EP1979334B1 (de)
JP (1) JP5102781B2 (de)
KR (1) KR100875596B1 (de)
CN (1) CN101379049B (de)
AT (1) ATE513820T1 (de)
CA (1) CA2637336A1 (de)
ES (1) ES2369634T3 (de)
HK (1) HK1126194A1 (de)
MX (1) MX2008009939A (de)
WO (1) WO2007089101A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20060017929A (ko) * 2004-08-04 2006-02-28 동화약품공업주식회사 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물
JP5102781B2 (ja) 2006-01-31 2012-12-19 ドン ファ ファーマシューティカル カンパニー リミテッド 新規のベンズアミジン誘導体、その製造方法およびそれを含む薬学組成物
NZ582700A (en) * 2007-07-27 2011-04-29 Dong Wha Pharm Co Ltd Novel benzamidine derivatives, process for the preparation thereof and pharmaceutical composition for preventing or treating osteoporosis comprising the same
US7655925B2 (en) * 2007-08-31 2010-02-02 Cymer, Inc. Gas management system for a laser-produced-plasma EUV light source
KR20100014090A (ko) * 2008-08-01 2010-02-10 동화약품주식회사 벤즈아미딘 유도체 또는 이의 염, 및 비스포스포네이트를 포함하는 골다공증의 예방 또는 치료용 약학 조성물
WO2010087517A1 (ja) * 2009-01-30 2010-08-05 帝人ファーマ株式会社 骨代謝異常に起因する疾患の予防剤又は治療剤
CN102993109A (zh) * 2012-12-03 2013-03-27 浙江工业大学 一种脒化合物的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE9900584A (et) * 1997-06-19 2000-08-15 Dupont Pharmaceuticals Company Neutraalse P1 spetsiifilisusrühmaga faktori Xa inhibiitorid
DE19755268A1 (de) 1997-12-12 1999-06-17 Merck Patent Gmbh Benzamidinderivate
EP1375482A4 (de) * 2001-04-05 2005-01-19 Sankyo Co Benzamidinderivate
KR100454767B1 (ko) * 2001-07-19 2004-11-03 동화약품공업주식회사 4-[(4-티아졸릴)페녹시]알콕시-벤즈아미딘 유도체의골다공증 예방 및 치료제로서의 용도
US7351727B2 (en) * 2003-09-02 2008-04-01 Bristol-Myers Squibb Company Inhibitors of 15-lipoxygenase
ATE499938T1 (de) * 2004-07-05 2011-03-15 Dong Wha Pharm Co Ltd Pharmazeutische zusammensetzung zur behandlung von knochenfrakturen
KR20060017929A (ko) 2004-08-04 2006-02-28 동화약품공업주식회사 티아졸 유도체가 치환된 신규한 벤즈아미딘 유도체, 그의제조방법 및 이를 유효성분으로 하는 약학 조성물
JP5102781B2 (ja) 2006-01-31 2012-12-19 ドン ファ ファーマシューティカル カンパニー リミテッド 新規のベンズアミジン誘導体、その製造方法およびそれを含む薬学組成物

Also Published As

Publication number Publication date
CA2637336A1 (en) 2007-08-09
EP1979334A1 (de) 2008-10-15
EP1979334A4 (de) 2010-09-08
EP1979334B1 (de) 2011-06-22
JP5102781B2 (ja) 2012-12-19
HK1126194A1 (en) 2009-08-28
US20090054642A1 (en) 2009-02-26
ES2369634T3 (es) 2011-12-02
CN101379049B (zh) 2012-01-04
MX2008009939A (es) 2008-11-18
CN101379049A (zh) 2009-03-04
KR100875596B1 (ko) 2008-12-23
WO2007089101A1 (en) 2007-08-09
US7943646B2 (en) 2011-05-17
JP2009525321A (ja) 2009-07-09
KR20070079043A (ko) 2007-08-03

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