ATE512362T1 - Antikörper und peptidantigene zur produktion von antikörpern mit einer selektiven bindungsspezifität zu bioaktivem intaktem parathyroidhormon (pth) 1-84 - Google Patents

Antikörper und peptidantigene zur produktion von antikörpern mit einer selektiven bindungsspezifität zu bioaktivem intaktem parathyroidhormon (pth) 1-84

Info

Publication number
ATE512362T1
ATE512362T1 AT05852305T AT05852305T ATE512362T1 AT E512362 T1 ATE512362 T1 AT E512362T1 AT 05852305 T AT05852305 T AT 05852305T AT 05852305 T AT05852305 T AT 05852305T AT E512362 T1 ATE512362 T1 AT E512362T1
Authority
AT
Austria
Prior art keywords
antibodies
pth
peptide antigens
parathyroid hormone
production
Prior art date
Application number
AT05852305T
Other languages
English (en)
Inventor
Richard J Zahradnik
Jeffrey R Lavigne
Original Assignee
Richard J Zahradnik
Jeffrey R Lavigne
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richard J Zahradnik, Jeffrey R Lavigne filed Critical Richard J Zahradnik
Application granted granted Critical
Publication of ATE512362T1 publication Critical patent/ATE512362T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/635Parathyroid hormone, i.e. parathormone; Parathyroid hormone-related peptides
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/537Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05852305T 2004-11-29 2005-11-29 Antikörper und peptidantigene zur produktion von antikörpern mit einer selektiven bindungsspezifität zu bioaktivem intaktem parathyroidhormon (pth) 1-84 ATE512362T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/998,927 US7226749B2 (en) 2000-12-05 2004-11-29 Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (PTH) 1-84
PCT/US2005/042962 WO2006058300A2 (en) 2004-11-29 2005-11-29 Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (pth) 1-84

Publications (1)

Publication Number Publication Date
ATE512362T1 true ATE512362T1 (de) 2011-06-15

Family

ID=36498607

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05852305T ATE512362T1 (de) 2004-11-29 2005-11-29 Antikörper und peptidantigene zur produktion von antikörpern mit einer selektiven bindungsspezifität zu bioaktivem intaktem parathyroidhormon (pth) 1-84

Country Status (12)

Country Link
US (1) US7226749B2 (de)
EP (1) EP1817584B1 (de)
JP (1) JP5028269B2 (de)
KR (1) KR101143726B1 (de)
CN (1) CN101095053B (de)
AT (1) ATE512362T1 (de)
CA (1) CA2589471C (de)
DK (1) DK1817584T3 (de)
ES (1) ES2367131T3 (de)
PT (1) PT1817584E (de)
RU (1) RU2460737C2 (de)
WO (1) WO2006058300A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
US6838264B2 (en) * 2000-12-05 2005-01-04 Immutopics, Inc. Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (PTH) 1-84
CN101355959B (zh) * 2005-11-10 2013-02-27 密歇根理工大学管理委员会 黑熊甲状旁腺素和使用黑熊甲状旁腺素的方法
US8012694B2 (en) * 2006-09-14 2011-09-06 Immutopics, Inc. Assay for the detection of phosphorylated PTH
CA2782640A1 (en) 2009-12-07 2011-06-16 Michigan Technological University Black bear parathyroid hormone and methods of using black bear parathyroid hormone
EP2631247A1 (de) * 2012-02-22 2013-08-28 Immundiagnostik AG Mittel und Verfahren zum Messen des Parathyroid-Hormons bei unter oxidativem Stress leidenden Patienten

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4341755A (en) 1980-07-15 1982-07-27 Immuno Nuclear Corporation Parathyroid radioimmunoassay
DE4434551A1 (de) * 1994-09-28 1996-04-04 Forssmann Wolf Georg Prof Dr D Peptide aus der Sequenz des hPTH (1-37)
IL121659A (en) 1996-10-25 2000-07-16 Bayer Ag Method for determining CPSA in a blood sample
US6689566B1 (en) 1999-01-14 2004-02-10 Scantibodies Laboratory, Inc. Methods, kits, and antibodies for detecting parathyroid hormone
US7820393B2 (en) * 1999-01-14 2010-10-26 Scantibodies Laboratory, Inc. Methods, kits and antibodies for detecting parathyroid hormone
DE19961350A1 (de) * 1999-12-17 2001-06-21 Immundiagnostik Ag Verfahren zur Bestimmung der Parathormon-Aktivität in einer menschlichen Probe
EP1303536B1 (de) 2000-07-19 2010-03-17 Advanced Research And Technology Institute, Inc. Neuer fibroblastwachstumsfaktor (fgf23) und methoden zur verwendung
CN101275136A (zh) 2000-08-11 2008-10-01 麒麟医药株式会社 调节磷酸代谢,钙代谢,钙化和维生素d代谢的多肽及其编码dna
US6838264B2 (en) * 2000-12-05 2005-01-04 Immutopics, Inc. Antibodies and peptide antigens for producing antibodies having a selective binding specificity to bioactive intact parathyroid hormone (PTH) 1-84
DE10116552A1 (de) * 2001-04-03 2002-10-10 Abc Armbruster Biochemicals Verfahren zur Bestimmung der wirksamen Parathormon-Aktivität in einer Probe
US20030082179A1 (en) * 2001-07-03 2003-05-01 Hutchison James Scott Parathyroid hormone antibodies and related methods
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone

Also Published As

Publication number Publication date
EP1817584A4 (de) 2008-03-05
RU2460737C2 (ru) 2012-09-10
CA2589471C (en) 2013-10-29
EP1817584A2 (de) 2007-08-15
ES2367131T3 (es) 2011-10-28
CN101095053B (zh) 2013-01-16
KR101143726B1 (ko) 2012-05-09
KR20070102499A (ko) 2007-10-18
US20050095236A1 (en) 2005-05-05
RU2007124371A (ru) 2009-01-10
WO2006058300A3 (en) 2006-09-21
CN101095053A (zh) 2007-12-26
PT1817584E (pt) 2011-08-12
WO2006058300A2 (en) 2006-06-01
JP2008521824A (ja) 2008-06-26
US7226749B2 (en) 2007-06-05
DK1817584T3 (da) 2011-06-27
EP1817584B1 (de) 2011-06-08
JP5028269B2 (ja) 2012-09-19
CA2589471A1 (en) 2006-06-01

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