ATE469917T2 - Verfahren zur gewinnung von antikörpern - Google Patents
Verfahren zur gewinnung von antikörpern Download PDFInfo
- Publication number
- ATE469917T2 ATE469917T2 AT05803527T AT05803527T ATE469917T2 AT E469917 T2 ATE469917 T2 AT E469917T2 AT 05803527 T AT05803527 T AT 05803527T AT 05803527 T AT05803527 T AT 05803527T AT E469917 T2 ATE469917 T2 AT E469917T2
- Authority
- AT
- Austria
- Prior art keywords
- relates
- obtaining antibodies
- yield
- subjected
- manufacture
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 230000002934 lysing effect Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0425534.5A GB0425534D0 (en) | 2004-11-19 | 2004-11-19 | Process for obtaining antibodies |
| PCT/GB2005/004397 WO2006054063A1 (en) | 2004-11-19 | 2005-11-16 | Process for obtaining antibodies |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469917T2 true ATE469917T2 (de) | 2010-06-15 |
Family
ID=33548568
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05803527T ATE469917T2 (de) | 2004-11-19 | 2005-11-16 | Verfahren zur gewinnung von antikörpern |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US8969036B2 (de) |
| EP (1) | EP1814912B2 (de) |
| JP (1) | JP4843616B2 (de) |
| CN (1) | CN101065402B (de) |
| AT (1) | ATE469917T2 (de) |
| AU (1) | AU2005305681B2 (de) |
| CA (1) | CA2584226C (de) |
| DE (1) | DE602005021678D1 (de) |
| ES (1) | ES2346673T5 (de) |
| GB (1) | GB0425534D0 (de) |
| WO (1) | WO2006054063A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0425537D0 (en) * | 2004-11-19 | 2004-12-22 | Celltech R&D Ltd | Process for obtaining antibodies |
| HUE046992T2 (hu) | 2007-07-09 | 2020-04-28 | Genentech Inc | Diszulfidkötés redukciójának megelõzése polipeptidek rekombináns elõállítása során |
| CN101802192A (zh) | 2007-10-15 | 2010-08-11 | 中外制药株式会社 | 抗体的制备方法 |
| SMT201800549T1 (it) | 2009-09-24 | 2018-11-09 | Ucb Biopharma Sprl | Ceppo batterico per espressione di proteina ricombinante, avente attivita' di chaperone a conservazione di degp carente di proteasi, e geni tsp e ptr con knockout |
| GB201000591D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial hoist strain |
| GB201000587D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial hoist strain |
| GB201000590D0 (en) | 2010-01-14 | 2010-03-03 | Ucb Pharma Sa | Bacterial host strain |
| GB201001791D0 (en) * | 2010-02-03 | 2010-03-24 | Ucb Pharma Sa | Process for obtaining antibodies |
| GB201012599D0 (en) | 2010-07-27 | 2010-09-08 | Ucb Pharma Sa | Process for purifying proteins |
| MX348738B (es) | 2011-07-13 | 2017-06-27 | Ucb Pharma Sa | Cepa huesped bacteriana que expresa dsbc recombinante. |
| GB201208367D0 (en) | 2012-05-14 | 2012-06-27 | Ucb Pharma Sa | Biological product |
| CN102757496B (zh) * | 2012-06-07 | 2014-06-18 | 山东泉港药业有限公司 | 一种抗vegf抗体片段的纯化制备方法 |
| PT3237433T (pt) | 2014-12-22 | 2025-10-21 | Ucb Biopharma Sprl | Método de fabrico de proteína |
| DK3237432T3 (da) * | 2014-12-22 | 2023-11-20 | UCB Biopharma SRL | Proteinfremstilling |
| GB201506869D0 (en) * | 2015-04-22 | 2015-06-03 | Ucb Biopharma Sprl | Method |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5328989B2 (de) | 1974-05-27 | 1978-08-17 | ||
| WO1991001367A1 (en) * | 1989-07-20 | 1991-02-07 | Bioeng, Inc. | Supercritical fluid disruption of and extraction from microbial cells |
| JP3951062B2 (ja) | 1991-09-19 | 2007-08-01 | ジェネンテック・インコーポレーテッド | 少なくとも遊離のチオールとして存在するシステインを有する抗体フラグメントの大腸菌での発現、2官能性F(ab’)2抗体の産生のための使用 |
| GB9215540D0 (en) * | 1992-07-22 | 1992-09-02 | Celltech Ltd | Protein expression system |
| US6455287B1 (en) * | 1995-02-23 | 2002-09-24 | Wyeth | Mechanical disruption of bacterial cells for plasmid recovery |
| DE19513676A1 (de) * | 1995-04-11 | 1996-10-17 | Behringwerke Ag | Cytoplasmatische Expression von Antikörpern, Antikörperfragmenten und Antikörperfragmentfusionsmolekülen in E.coli |
| US6120985A (en) * | 1997-10-31 | 2000-09-19 | Bbi Bioseq, Inc. | Pressure-enhanced extraction and purification |
| GB0319601D0 (en) | 2003-08-20 | 2003-09-24 | Sandoz Ag | Production process |
-
2004
- 2004-11-19 GB GBGB0425534.5A patent/GB0425534D0/en not_active Ceased
-
2005
- 2005-11-16 DE DE602005021678T patent/DE602005021678D1/de not_active Expired - Lifetime
- 2005-11-16 CN CN2005800395236A patent/CN101065402B/zh not_active Expired - Lifetime
- 2005-11-16 EP EP05803527.0A patent/EP1814912B2/de not_active Expired - Lifetime
- 2005-11-16 US US11/791,107 patent/US8969036B2/en active Active
- 2005-11-16 AT AT05803527T patent/ATE469917T2/de active
- 2005-11-16 AU AU2005305681A patent/AU2005305681B2/en not_active Expired
- 2005-11-16 JP JP2007542089A patent/JP4843616B2/ja not_active Expired - Lifetime
- 2005-11-16 WO PCT/GB2005/004397 patent/WO2006054063A1/en not_active Ceased
- 2005-11-16 ES ES05803527.0T patent/ES2346673T5/es not_active Expired - Lifetime
- 2005-11-16 CA CA2584226A patent/CA2584226C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2346673T5 (es) | 2018-02-15 |
| ES2346673T3 (es) | 2010-10-19 |
| EP1814912B1 (de) | 2010-06-02 |
| JP2008520225A (ja) | 2008-06-19 |
| US8969036B2 (en) | 2015-03-03 |
| AU2005305681A1 (en) | 2006-05-26 |
| CA2584226C (en) | 2015-09-15 |
| US20080003644A1 (en) | 2008-01-03 |
| JP4843616B2 (ja) | 2011-12-21 |
| EP1814912A1 (de) | 2007-08-08 |
| WO2006054063A1 (en) | 2006-05-26 |
| DE602005021678D1 (de) | 2010-07-15 |
| GB0425534D0 (en) | 2004-12-22 |
| CA2584226A1 (en) | 2006-05-26 |
| CN101065402A (zh) | 2007-10-31 |
| CN101065402B (zh) | 2011-07-20 |
| EP1814912B2 (de) | 2017-10-25 |
| AU2005305681B2 (en) | 2011-04-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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