ATE511551T1 - Aus lebendigen tumorzellen ausgewählte aptamere und deren verwendung - Google Patents
Aus lebendigen tumorzellen ausgewählte aptamere und deren verwendungInfo
- Publication number
- ATE511551T1 ATE511551T1 AT05741923T AT05741923T ATE511551T1 AT E511551 T1 ATE511551 T1 AT E511551T1 AT 05741923 T AT05741923 T AT 05741923T AT 05741923 T AT05741923 T AT 05741923T AT E511551 T1 ATE511551 T1 AT E511551T1
- Authority
- AT
- Austria
- Prior art keywords
- tumor cells
- aptamers selected
- living tumor
- aptamers
- living
- Prior art date
Links
- 108091023037 Aptamer Proteins 0.000 title abstract 2
- 210000004881 tumor cell Anatomy 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 238000003745 diagnosis Methods 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6811—Selection methods for production or design of target specific oligonucleotides or binding molecules
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pathology (AREA)
- Hospice & Palliative Care (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0402774A FR2867784B1 (fr) | 2004-03-17 | 2004-03-17 | Aptameres selectionnes a partir de cellules vivantes tumorales et leurs applications |
| PCT/FR2005/000656 WO2005093097A1 (fr) | 2004-03-17 | 2005-03-17 | Aptameres selectionnes a partir de cellules vivantes tumorales et leurs applications. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE511551T1 true ATE511551T1 (de) | 2011-06-15 |
Family
ID=34896603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05741923T ATE511551T1 (de) | 2004-03-17 | 2005-03-17 | Aus lebendigen tumorzellen ausgewählte aptamere und deren verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080227735A1 (de) |
| EP (1) | EP1756305B1 (de) |
| JP (1) | JP4807591B2 (de) |
| AT (1) | ATE511551T1 (de) |
| CA (1) | CA2559871A1 (de) |
| FR (1) | FR2867784B1 (de) |
| WO (1) | WO2005093097A1 (de) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004092384A2 (en) | 2003-04-17 | 2004-10-28 | Affectis Pharmaceuticals Ag | Means and methods for diagnosing and treating affective disorders |
| EP2078751A1 (de) * | 2008-01-11 | 2009-07-15 | Commissariat A L'energie Atomique | Spezifische zur Unterdrückung der Zellmigration und -invasion durch Krebszellen erzeugte Aptamere, Verfahren zur Auswahl derartiger Aptamere und ihre Verwendung |
| CA2729602A1 (en) | 2008-07-08 | 2010-01-14 | Oncomed Pharmaceuticals, Inc. | Notch1 receptor binding agents and methods of use thereof |
| EP2159286A1 (de) * | 2008-09-01 | 2010-03-03 | Consiglio Nazionale Delle Ricerche | Verfahren zur Gewinnung von Oligonucleotid-Aptameren und Verwendungen damit |
| TWI535445B (zh) | 2010-01-12 | 2016-06-01 | 安可美德藥物股份有限公司 | Ｗｎｔ拮抗劑及治療和篩選方法 |
| AR080301A1 (es) | 2010-02-24 | 2012-03-28 | Immunogen Inc | Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos |
| MX338932B (es) | 2010-03-12 | 2016-05-06 | Immunogen Inc | Moleculas de union cd37 y sus inmunoconjugados. |
| ITRM20100537A1 (it) | 2010-10-12 | 2012-04-12 | Consiglio Nazionale Ricerche | Aptamero inibitore del recettore tirosina chinasi axl per uso in terapia |
| FR2967423B1 (fr) | 2010-11-12 | 2017-12-15 | Commissariat Energie Atomique | Ligand specifique de l'annexine 2 |
| FR2969174B1 (fr) * | 2010-12-16 | 2014-03-14 | Commissariat Energie Atomique | Ligand specifique de la proteine lar |
| CN102864150B (zh) * | 2011-06-03 | 2013-08-21 | 湖南大学 | 一种可识别hcv ns5a蛋白的核酸适体、核酸适体的衍生物及其筛选方法和应用 |
| CN102229933A (zh) * | 2011-06-03 | 2011-11-02 | 湖南大学 | 可识别hcv ns5a蛋白的核酸适体、核酸适体的衍生物及其筛选方法和应用 |
| CN102229932B (zh) * | 2011-06-03 | 2013-02-27 | 湖南大学 | 可识别hcv e1e2蛋白的核酸适体、核酸适体的衍生物及其筛选方法和应用 |
| CN102766693B (zh) * | 2012-07-25 | 2013-08-28 | 湖南大学 | 可用于检测人肝癌细胞株smmc-7721的核酸适体及其筛选方法和应用 |
| WO2014127484A1 (en) * | 2013-02-21 | 2014-08-28 | British Columbia Cancer Agency Branch | Spike-in control nucleic acids for sample tracking |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6280932B1 (en) * | 1990-06-11 | 2001-08-28 | Gilead Sciences, Inc. | High affinity nucleic acid ligands to lectins |
| US5580737A (en) * | 1990-06-11 | 1996-12-03 | Nexstar Pharmaceuticals, Inc. | High-affinity nucleic acid ligands that discriminate between theophylline and caffeine |
| JP2002510790A (ja) * | 1998-04-06 | 2002-04-09 | ブンセン ラッシュ ラボラトリーズ インコーポレーテッド | 指向的進化バイオセンサ |
| DE60042021D1 (de) * | 1999-07-29 | 2009-05-28 | Gilead Sciences Inc | Nukleinsäureliganden für den hepatozytischen wachstumsfaktor/dispersionsfaktor (hgf/sf) und seines c-met rezeptors |
| CA2450793A1 (en) * | 2001-06-20 | 2002-12-27 | Prochon Biotech Ltd. | Antibodies that block receptor protein tyrosine kinase activation, methods of screening for and uses thereof |
| ATE516366T1 (de) * | 2002-07-25 | 2011-07-15 | Archemix Corp | Regulierte aptamer-therapeutika |
-
2004
- 2004-03-17 FR FR0402774A patent/FR2867784B1/fr not_active Expired - Fee Related
-
2005
- 2005-03-17 CA CA002559871A patent/CA2559871A1/fr not_active Abandoned
- 2005-03-17 AT AT05741923T patent/ATE511551T1/de not_active IP Right Cessation
- 2005-03-17 EP EP05741923A patent/EP1756305B1/de not_active Expired - Lifetime
- 2005-03-17 JP JP2007503381A patent/JP4807591B2/ja not_active Expired - Fee Related
- 2005-03-17 WO PCT/FR2005/000656 patent/WO2005093097A1/fr not_active Ceased
- 2005-03-17 US US10/593,256 patent/US20080227735A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| FR2867784A1 (fr) | 2005-09-23 |
| CA2559871A1 (fr) | 2005-10-06 |
| EP1756305B1 (de) | 2011-06-01 |
| EP1756305A1 (de) | 2007-02-28 |
| US20080227735A1 (en) | 2008-09-18 |
| JP2007529213A (ja) | 2007-10-25 |
| JP4807591B2 (ja) | 2011-11-02 |
| WO2005093097A1 (fr) | 2005-10-06 |
| FR2867784B1 (fr) | 2006-06-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |