FR2967423B1 - Ligand specifique de l'annexine 2 - Google Patents

Ligand specifique de l'annexine 2

Info

Publication number
FR2967423B1
FR2967423B1 FR1004412A FR1004412A FR2967423B1 FR 2967423 B1 FR2967423 B1 FR 2967423B1 FR 1004412 A FR1004412 A FR 1004412A FR 1004412 A FR1004412 A FR 1004412A FR 2967423 B1 FR2967423 B1 FR 2967423B1
Authority
FR
France
Prior art keywords
annex
specific ligand
ligand
specific
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR1004412A
Other languages
English (en)
Other versions
FR2967423A1 (fr
Inventor
Frederic Duconge
Agnes Cibiel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Original Assignee
Commissariat a lEnergie Atomique CEA
Commissariat a lEnergie Atomique et aux Energies Alternatives CEA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Commissariat a lEnergie Atomique CEA, Commissariat a lEnergie Atomique et aux Energies Alternatives CEA filed Critical Commissariat a lEnergie Atomique CEA
Priority to FR1004412A priority Critical patent/FR2967423B1/fr
Priority to US13/884,528 priority patent/US8940886B2/en
Priority to DK11799129.9T priority patent/DK2638164T3/en
Priority to EP11799129.9A priority patent/EP2638164B1/fr
Priority to PCT/IB2011/055019 priority patent/WO2012063219A1/fr
Publication of FR2967423A1 publication Critical patent/FR2967423A1/fr
Application granted granted Critical
Publication of FR2967423B1 publication Critical patent/FR2967423B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/02Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with ribosyl as saccharide radical
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/10Type of nucleic acid
    • C12N2310/16Aptamers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/32Chemical structure of the sugar
    • C12N2310/3222'-R Modification
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/34Spatial arrangement of the modifications
    • C12N2310/344Position-specific modifications, e.g. on every purine, at the 3'-end
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00Structure or type of the nucleic acid
    • C12N2310/30Chemical structure
    • C12N2310/35Nature of the modification
    • C12N2310/351Conjugate
    • C12N2310/3517Marker; Tag
FR1004412A 2010-11-12 2010-11-12 Ligand specifique de l'annexine 2 Expired - Fee Related FR2967423B1 (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR1004412A FR2967423B1 (fr) 2010-11-12 2010-11-12 Ligand specifique de l'annexine 2
US13/884,528 US8940886B2 (en) 2010-11-12 2011-11-10 Specific ligand for annexin 2
DK11799129.9T DK2638164T3 (en) 2010-11-12 2011-11-10 SPECIFIC LIGAND FOR ANNEXIN 2
EP11799129.9A EP2638164B1 (fr) 2010-11-12 2011-11-10 Ligand specifique de l'annexine 2
PCT/IB2011/055019 WO2012063219A1 (fr) 2010-11-12 2011-11-10 Ligand specifique de l'annexine 2

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR1004412A FR2967423B1 (fr) 2010-11-12 2010-11-12 Ligand specifique de l'annexine 2

Publications (2)

Publication Number Publication Date
FR2967423A1 FR2967423A1 (fr) 2012-05-18
FR2967423B1 true FR2967423B1 (fr) 2017-12-15

Family

ID=44148878

Family Applications (1)

Application Number Title Priority Date Filing Date
FR1004412A Expired - Fee Related FR2967423B1 (fr) 2010-11-12 2010-11-12 Ligand specifique de l'annexine 2

Country Status (5)

Country Link
US (1) US8940886B2 (fr)
EP (1) EP2638164B1 (fr)
DK (1) DK2638164T3 (fr)
FR (1) FR2967423B1 (fr)
WO (1) WO2012063219A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3934764A4 (fr) * 2019-03-07 2023-01-25 University of Miami Aptamères d'arn et utilisations associées

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2867784B1 (fr) * 2004-03-17 2006-06-09 Commissariat Energie Atomique Aptameres selectionnes a partir de cellules vivantes tumorales et leurs applications

Also Published As

Publication number Publication date
DK2638164T3 (en) 2018-07-30
EP2638164A1 (fr) 2013-09-18
US8940886B2 (en) 2015-01-27
FR2967423A1 (fr) 2012-05-18
WO2012063219A1 (fr) 2012-05-18
EP2638164B1 (fr) 2018-04-25
US20130266515A1 (en) 2013-10-10

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