ATE507844T1 - Verfahren zur herstellung eines homogenen doxorubicin-transferrin kojugates - Google Patents
Verfahren zur herstellung eines homogenen doxorubicin-transferrin kojugatesInfo
- Publication number
- ATE507844T1 ATE507844T1 AT02736574T AT02736574T ATE507844T1 AT E507844 T1 ATE507844 T1 AT E507844T1 AT 02736574 T AT02736574 T AT 02736574T AT 02736574 T AT02736574 T AT 02736574T AT E507844 T1 ATE507844 T1 AT E507844T1
- Authority
- AT
- Austria
- Prior art keywords
- molecules
- drug
- homogeneous
- conjugate
- cojugate
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/644—Transferrin, e.g. a lactoferrin or ovotransferrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29068401P | 2001-05-15 | 2001-05-15 | |
US32953501P | 2001-10-17 | 2001-10-17 | |
PCT/US2002/011891 WO2002091991A2 (en) | 2001-05-15 | 2002-05-15 | Substantially homogeneous bio-affecting material having a pre-determined ratio of bioaffecting component to cell targeting component, the method for making such a material and the method of its use |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE507844T1 true ATE507844T1 (de) | 2011-05-15 |
Family
ID=26966358
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02736574T ATE507844T1 (de) | 2001-05-15 | 2002-05-15 | Verfahren zur herstellung eines homogenen doxorubicin-transferrin kojugates |
Country Status (10)
Country | Link |
---|---|
US (2) | US20040167061A1 (de) |
EP (1) | EP1414299B1 (de) |
JP (1) | JP2005514322A (de) |
CN (1) | CN1307200C (de) |
AT (1) | ATE507844T1 (de) |
CA (1) | CA2447391C (de) |
DE (1) | DE60239938D1 (de) |
HK (1) | HK1067492A1 (de) |
PL (1) | PL373511A1 (de) |
WO (1) | WO2002091991A2 (de) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN100372566C (zh) | 2001-05-15 | 2008-03-05 | 福克医药公司 | 治疗病毒感染的靶向给药组合物及方法 |
US7001991B2 (en) | 2001-05-15 | 2006-02-21 | Faulk Pharmaceuticals, Inc. | Targeted delivery of bioaffecting compounds for the treatment of cancer |
EP1395264A4 (de) * | 2001-05-16 | 2006-03-22 | Faulk Pharmaceuticals Inc | Gezielte freisetzung von arzneimitteln zur behandlung von parasitischen infektionen |
WO2003032899A2 (en) * | 2001-10-17 | 2003-04-24 | Faulk Pharmaceuticals, Inc | Methods and materials for targeting and affecting selected cells |
WO2011097149A2 (en) * | 2010-02-03 | 2011-08-11 | Oncbiomune, L.L.C. | Taxane-and taxoid-protein compositions |
JP5378469B2 (ja) * | 2011-08-11 | 2013-12-25 | 学校法人 日本歯科大学 | 医療用薬剤 |
KR20140048404A (ko) * | 2012-10-11 | 2014-04-24 | 포항공과대학교 산학협력단 | 저밀도 지단백질 유사 나노입자 및 이를 포함하는 간 표적 진단 및 치료용 조성물 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US28686A (en) * | 1860-06-12 | Improvement in steam-radiators | ||
GB2116979B (en) * | 1982-02-25 | 1985-05-15 | Ward Page Faulk | Conjugates of proteins with anti-tumour agents |
JPH0720886B2 (ja) * | 1983-08-10 | 1995-03-08 | ペ−ジ フオ−ク,ウオ−ド | タンパク質と抗腫瘍剤との複合体 |
GB8519457D0 (en) * | 1985-08-02 | 1985-09-11 | Faulk Ward Page | Tumour imaging agents |
US5264373A (en) * | 1987-02-17 | 1993-11-23 | Abbott Laboratories | Fluorescence polarization immunoassay for tetrahydrocannabinoids |
US5208323A (en) * | 1989-08-10 | 1993-05-04 | Universite Laval | Coupling of an anti-tumor to an antibody using glutaraldehyde preactivated anti-tumor agent |
US5393737A (en) * | 1992-08-20 | 1995-02-28 | Health Research, Inc. | Cytotoxic drug conjugates for treatment of neoplastic diseases |
WO1995003831A1 (en) * | 1993-08-02 | 1995-02-09 | Prizm Pharmaceuticals, Inc. | Monogenous preparations of cytotoxic conjugates |
AU2283595A (en) * | 1994-04-08 | 1995-10-30 | Receptagen Corporation | Receptor modulating agents and methods relating thereto |
DE19636889A1 (de) * | 1996-09-11 | 1998-03-12 | Felix Dr Kratz | Antineoplastisch wirkende Transferrin- und Albuminkonjugate zytostatischer Verbindungen aus der Gruppe der Anthrazykline, Alkylantien, Antimetabolite und Cisplatin-Analoga und diese enthaltende Arzneimittel |
US6020316A (en) * | 1997-09-25 | 2000-02-01 | Lanks; Karl W. | Glutaraldehyde modified chemotherapeutic agents and methods of use thereof |
JP2002095476A (ja) * | 2000-09-20 | 2002-04-02 | Eisai Co Ltd | トランスフェリン受容体を介した遺伝子導入法 |
AU2002254400B2 (en) * | 2001-03-23 | 2007-08-09 | Napro Biotherapeutics, Inc. | Molecular conjugates for use in treatment of cancer |
US7001991B2 (en) * | 2001-05-15 | 2006-02-21 | Faulk Pharmaceuticals, Inc. | Targeted delivery of bioaffecting compounds for the treatment of cancer |
EP1395264A4 (de) * | 2001-05-16 | 2006-03-22 | Faulk Pharmaceuticals Inc | Gezielte freisetzung von arzneimitteln zur behandlung von parasitischen infektionen |
WO2003032899A2 (en) * | 2001-10-17 | 2003-04-24 | Faulk Pharmaceuticals, Inc | Methods and materials for targeting and affecting selected cells |
-
2002
- 2002-05-15 JP JP2002588910A patent/JP2005514322A/ja active Pending
- 2002-05-15 EP EP02736574A patent/EP1414299B1/de not_active Expired - Lifetime
- 2002-05-15 AT AT02736574T patent/ATE507844T1/de not_active IP Right Cessation
- 2002-05-15 CA CA2447391A patent/CA2447391C/en not_active Expired - Fee Related
- 2002-05-15 US US10/477,999 patent/US20040167061A1/en not_active Abandoned
- 2002-05-15 DE DE60239938T patent/DE60239938D1/de not_active Expired - Lifetime
- 2002-05-15 PL PL02373511A patent/PL373511A1/xx not_active Application Discontinuation
- 2002-05-15 CN CNB028142403A patent/CN1307200C/zh not_active Expired - Fee Related
- 2002-05-15 WO PCT/US2002/011891 patent/WO2002091991A2/en active Application Filing
-
2004
- 2004-11-04 HK HK04108682.2A patent/HK1067492A1/xx not_active IP Right Cessation
-
2008
- 2008-11-13 US US12/270,110 patent/US20090068104A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
CA2447391C (en) | 2012-08-28 |
CA2447391A1 (en) | 2002-11-21 |
WO2002091991A3 (en) | 2004-02-19 |
CN1529551A (zh) | 2004-09-15 |
WO2002091991A2 (en) | 2002-11-21 |
US20090068104A1 (en) | 2009-03-12 |
CN1307200C (zh) | 2007-03-28 |
EP1414299A4 (de) | 2005-06-22 |
HK1067492A1 (en) | 2005-04-15 |
JP2005514322A (ja) | 2005-05-19 |
PL373511A1 (en) | 2005-09-05 |
EP1414299A2 (de) | 2004-05-06 |
DE60239938D1 (de) | 2011-06-16 |
US20040167061A1 (en) | 2004-08-26 |
EP1414299B1 (de) | 2011-05-04 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1120070T1 (el) | Μεθοδοi θεραπευτικης αγωγης με τη χρηση συζευγματων αντισωματος εναντι-erbb-μεϋτανσινοειδους | |
MX2021007296A (es) | Grupo de moléculas biológicamente activas. | |
DE602005018043D1 (de) | Liposomale formulierungen mit dihydrosphingomyelin und verfahren zu ihrer verwendung | |
ATE473759T1 (de) | Bifunktionelle moleküle sowie darauf basierende therapien. | |
CY1113984T1 (el) | Προϊοντα συζευξης μεϋτανσινοειδους dm1 με αντισωμα trastuzumab, συνδεδεμενα μεσω μη-διασπασιμου συνδετηρα και χρηση αυτων στη θεραπεια ογκων | |
UY27438A1 (es) | Composición farmaceútica que comprende un conjugado oligómero-farmaco insulina, método para tratar deficiencia de insulina en un sujeto, método para proveer una composición farmacéutica. | |
MY137552A (en) | Methods for treating rheumatic diseases using a soluble ctla4 molecule | |
CY1112362T1 (el) | Πολυμερη βασιζομενα σε κυκλοδεξτρινη για χορηγηση των θεραπευτικων μεσων που ειναι ομοιοπολικως δεσμευμενα σε αυτα | |
ATE472338T1 (de) | Anti-cd70 antikörper-arzneimittelkonjugate und ihre verwendung zur behandlung von krebs | |
BRPI0517843A (pt) | compostos de moléculas conjugadas com a atividade de absorção de células aumentada | |
ES2534303T3 (es) | Procedimientos y composiciones que implican miARN y moléculas inhibidoras de miARN | |
ATE334676T1 (de) | Photo-empfindlichkeit-erhöhende conjugate zur targeting von pathogene | |
ATE258946T1 (de) | Verfahren zur herstellung von polyamidketten von genauer länge und deren konjugate mit proteinen | |
NZ288883A (en) | Conjugates comprising coagulation factors | |
ATE521366T1 (de) | Anwendung von amatoxin-konjugaten und phallotoxin-konjugaten mit makromolekülen zur krebstherapie und therapie von entzündungen | |
NO975547L (no) | Vaksiner med modifiserte meningokokk/polysakkarid-konjugater | |
WO2004013307A3 (en) | Compounds for targeting hepatocytes | |
DE60042369D1 (de) | Chemisch programmierbare immunität | |
ATE304709T1 (de) | Substanzen mit verzweigten linkermolekülen | |
ATE194776T1 (de) | Verfahren zur herstellung von lipid-konjugaten | |
ATE442861T1 (de) | Gegen antikörper gerichtete photodynamische therapie | |
ATE507844T1 (de) | Verfahren zur herstellung eines homogenen doxorubicin-transferrin kojugates | |
DE602005015855D1 (de) | Verfahren zur herstellung von immunogenen konjugaten | |
AU2002360350A8 (en) | Peptides that home to tumor lymphatic vasculature and methods of using same | |
ATE292475T1 (de) | Abgabesystem für ein mittel gegen schuppen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |