ATE507239T1 - Erhöhte sekretion/retention von wachstumshormonfreisetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptid - Google Patents
Erhöhte sekretion/retention von wachstumshormonfreisetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptidInfo
- Publication number
- ATE507239T1 ATE507239T1 AT05705515T AT05705515T ATE507239T1 AT E507239 T1 ATE507239 T1 AT E507239T1 AT 05705515 T AT05705515 T AT 05705515T AT 05705515 T AT05705515 T AT 05705515T AT E507239 T1 ATE507239 T1 AT E507239T1
- Authority
- AT
- Austria
- Prior art keywords
- ghrh
- species
- retention
- muscle cells
- specific signaling
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/60—Growth-hormone releasing factors (GH-RF) (Somatoliberin)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53758204P | 2004-01-20 | 2004-01-20 | |
PCT/US2005/000892 WO2005073371A2 (en) | 2004-01-20 | 2005-01-13 | Enhanced secretion/retention of growth hormone releasing hormone (ghrh) from muscle cells by species-specific signal peptide |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE507239T1 true ATE507239T1 (de) | 2011-05-15 |
Family
ID=34825931
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05705515T ATE507239T1 (de) | 2004-01-20 | 2005-01-13 | Erhöhte sekretion/retention von wachstumshormonfreisetzendem hormon (ghrh) aus muskelzellen durch speziesspezifisches signalpeptid |
Country Status (6)
Country | Link |
---|---|
US (1) | US7517863B2 (de) |
EP (1) | EP1713828B1 (de) |
AT (1) | ATE507239T1 (de) |
CA (1) | CA2595619A1 (de) |
DE (1) | DE602005027661D1 (de) |
WO (1) | WO2005073371A2 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7846720B2 (en) * | 2005-01-26 | 2010-12-07 | Vgx Pharmaceuticals, Inc. | Optimized high yield synthetic plasmids |
US8962818B2 (en) * | 2008-03-06 | 2015-02-24 | Vgx Pharmaceuticals, Inc. | Compositions comprising GHRH and GnRH and methods of using the same |
US8993316B2 (en) | 2011-11-16 | 2015-03-31 | Brian P. Hanley | Methods and compositions for gene therapy and GHRH therapy |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4224316A (en) | 1979-03-30 | 1980-09-23 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4228156A (en) | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223021A (en) | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223020A (en) | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4228158A (en) | 1979-03-30 | 1980-10-14 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4226857A (en) | 1979-03-30 | 1980-10-07 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4223019A (en) | 1979-03-30 | 1980-09-16 | Beckman Instruments, Inc. | Synthetic peptides having pituitary growth hormone releasing activity |
US4410512A (en) | 1981-12-28 | 1983-10-18 | Beckman Instruments, Inc. | Combinations having synergistic pituitary growth hormone releasing activity |
ZA844380B (en) * | 1983-07-05 | 1985-01-30 | Salk Inst For Biological Studi | Dna encoding a grf precursor |
US5134120A (en) | 1984-08-03 | 1992-07-28 | Cornell Research Foundation, Inc. | Use of growth hormone to enhance porcine weight gain |
US5036045A (en) | 1985-09-12 | 1991-07-30 | The University Of Virginia Alumni Patents Foundation | Method for increasing growth hormone secretion |
US4833166A (en) | 1987-05-01 | 1989-05-23 | Grosvenor Clark E | Growth hormone releasing hormone complementary peptides |
US4839344A (en) | 1987-06-12 | 1989-06-13 | Eastman Kodak Company | Polypeptide compounds having growth hormone releasing activity |
USRE33699E (en) | 1987-07-09 | 1991-09-24 | International Minerals & Chemical Corp. | Growth hormone-releasing factor analogs |
FR2622455B1 (fr) | 1987-11-04 | 1991-07-12 | Agronomique Inst Nat Rech | Application du facteur de stimulation de la secretion de l'hormone de croissance humaine, de ses fragments actifs et des analogues correspondants, pour augmenter la production laitiere et le poids des nouveau-nes chez les mammiferes |
US5023322A (en) | 1988-08-31 | 1991-06-11 | Mta Kutatas-Es Szervezetelemzo Intezete | Analogs of growth hormone releasing factor (GRF) and a method for the preparation thereof |
US5084442A (en) | 1988-09-06 | 1992-01-28 | Hoffmann-La Roche Inc. | Cyclic growth hormone releasing factor analogs and method for the manufacture thereof |
US5134210A (en) | 1989-07-27 | 1992-07-28 | Edwards Bill R | Acrylic resin composition |
US5137872A (en) | 1989-09-18 | 1992-08-11 | Pitman-Moore, Inc. | Growth hormone-releasing factor analogs |
ZA914983B (en) | 1990-06-29 | 1992-03-25 | Hoffmann La Roche | His-grf-analogs |
US5486505A (en) | 1990-07-24 | 1996-01-23 | Polygen Holding Corporation | Polypeptide compounds having growth hormone releasing activity |
JPH05507939A (ja) | 1991-04-09 | 1993-11-11 | エフ・ホフマン―ラ ロシユ アーゲー | 成長ホルモン放出因子の類似体 |
US5663146A (en) | 1991-08-22 | 1997-09-02 | Administrators Of The Tulane Educational Fund | Polypeptide analogues having growth hormone releasing activity |
US5298422A (en) | 1991-11-06 | 1994-03-29 | Baylor College Of Medicine | Myogenic vector systems |
US5545130A (en) | 1992-04-08 | 1996-08-13 | Genetronics, Inc. | Flow through electroporation method |
US6132419A (en) | 1992-05-22 | 2000-10-17 | Genetronics, Inc. | Electroporetic gene and drug therapy |
US5507724A (en) | 1992-07-01 | 1996-04-16 | Genetronics, Inc. | Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells |
US5439440A (en) | 1993-04-01 | 1995-08-08 | Genetronics, Inc. | Electroporation system with voltage control feedback for clinical applications |
US5702359A (en) | 1995-06-06 | 1997-12-30 | Genetronics, Inc. | Needle electrodes for mediated delivery of drugs and genes |
US5792747A (en) | 1995-01-24 | 1998-08-11 | The Administrators Of The Tulane Educational Fund | Highly potent agonists of growth hormone releasing hormone |
AU5441096A (en) | 1995-04-14 | 1996-10-30 | The Administrators Of The Tulane Eductional Fund | Analogs of growth hormone-releasing factor |
WO1997007826A1 (en) | 1995-08-29 | 1997-03-06 | Cbr Laboratories, Inc. | In vivo electroporation of cells |
EP1260229A3 (de) * | 2001-05-18 | 2002-12-11 | Sumitomo Pharmaceuticals Company, Limited | Anti-Autoimmunpräparat das Inhibitoren der Aktivität von Wachstumshormon freisetzenden-Faktor enthält |
WO2002097099A1 (en) * | 2001-05-29 | 2002-12-05 | Valentis, Inc. | Regulated expression of ghrh |
WO2003038112A2 (en) * | 2001-10-26 | 2003-05-08 | Baylor College Of Medicine | A composition and method to alter lean body mass and bone properties in a subject |
US20040204358A1 (en) * | 2003-01-28 | 2004-10-14 | Advisys, Inc. | Reducing culling in herd animals growth hormone releasing hormone (GHRH) |
EP1711187B1 (de) * | 2003-12-31 | 2010-05-12 | VGX Pharmaceuticals, LLC | Reduzierung von arthritis und lahmheit bei personen unter supllement von wachstumshormon freisetzendem hormon (ghrh) |
-
2005
- 2005-01-13 CA CA002595619A patent/CA2595619A1/en not_active Abandoned
- 2005-01-13 WO PCT/US2005/000892 patent/WO2005073371A2/en active Application Filing
- 2005-01-13 DE DE602005027661T patent/DE602005027661D1/de active Active
- 2005-01-13 US US11/034,682 patent/US7517863B2/en active Active
- 2005-01-13 AT AT05705515T patent/ATE507239T1/de not_active IP Right Cessation
- 2005-01-13 EP EP05705515A patent/EP1713828B1/de active Active
Also Published As
Publication number | Publication date |
---|---|
US20050171046A1 (en) | 2005-08-04 |
DE602005027661D1 (de) | 2011-06-09 |
WO2005073371A2 (en) | 2005-08-11 |
US7517863B2 (en) | 2009-04-14 |
WO2005073371A3 (en) | 2005-10-27 |
CA2595619A1 (en) | 2005-08-11 |
EP1713828A2 (de) | 2006-10-25 |
EP1713828B1 (de) | 2011-04-27 |
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