ATE50583T1 - Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten. - Google Patents

Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.

Info

Publication number
ATE50583T1
ATE50583T1 AT84109811T AT84109811T ATE50583T1 AT E50583 T1 ATE50583 T1 AT E50583T1 AT 84109811 T AT84109811 T AT 84109811T AT 84109811 T AT84109811 T AT 84109811T AT E50583 T1 ATE50583 T1 AT E50583T1
Authority
AT
Austria
Prior art keywords
bil
manufacture
acid derivatives
pharmaceutical preparations
preparations containing
Prior art date
Application number
AT84109811T
Other languages
English (en)
Inventor
Virginio Castagnola
E Giuliano Frigerio
Roberto Pellicciari
Aldo Roda
Original Assignee
Gipharmex Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gipharmex Spa filed Critical Gipharmex Spa
Application granted granted Critical
Publication of ATE50583T1 publication Critical patent/ATE50583T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT84109811T 1983-08-18 1984-08-17 Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten. ATE50583T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8322572A IT1212835B (it) 1983-08-18 1983-08-18 Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
EP84109811A EP0135782B1 (de) 1983-08-18 1984-08-17 Gallensäure-Derivate, Verfahren zu ihrer Herstellung und pharmazeutische Präparate, die sie enthalten

Publications (1)

Publication Number Publication Date
ATE50583T1 true ATE50583T1 (de) 1990-03-15

Family

ID=11197972

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84109811T ATE50583T1 (de) 1983-08-18 1984-08-17 Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.

Country Status (7)

Country Link
US (1) US4981983A (de)
EP (1) EP0135782B1 (de)
JP (1) JPH0144197B2 (de)
AT (1) ATE50583T1 (de)
DE (1) DE3481419D1 (de)
ES (1) ES8506047A1 (de)
IT (1) IT1212835B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196377B (it) * 1984-12-21 1988-11-16 Lehner Ag Derivati di acidi biliari,procedimento per la loro preparazione e relative composizioni farmaceutiche
HU206367B (en) * 1988-04-30 1992-10-28 Sandoz Ag Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts
IT1255449B (it) * 1992-06-30 1995-10-31 Fabio Berlati Uso di nor- e omo-derivati di acidi biliari come promotori di assorbimento di farmaci.
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
US6767904B2 (en) 1998-03-06 2004-07-27 Bringham Young University Steroid derived antibiotics
US6350738B1 (en) 1998-03-06 2002-02-26 Brigham Young University Steroid derived antibiotics
AU2002308295B2 (en) 2001-03-12 2007-08-23 Intercept Pharmaceuticals, Inc. Steroids as agonists for FXR
EP1734970B1 (de) 2004-03-12 2014-12-31 Intercept Pharmaceuticals, Inc. Behandlung von fibrose mit fxr-liganden
US10987362B2 (en) 2004-03-12 2021-04-27 Intercept Pharmaceuticals, Inc. Treatment of fibrosis using FXR ligands
ITMI20050912A1 (it) 2005-05-19 2006-11-20 Erregierre Spa Processo di preparazione di acidi 3-a-ya(b)-diidrossi-6-a(b)-alchil-5b-colanici
AU2008209566C1 (en) * 2007-01-19 2013-02-14 Intercept Pharmaceuticals, Inc. 23-substituted bile acids as TGR5 modulators and methods of use thereof
EP1947108A1 (de) * 2007-01-19 2008-07-23 Intercept Pharmaceuticals, Inc. TGR5-Modulatoren und Anwendungsverfahren dafür
EA020310B1 (ru) 2008-07-30 2014-10-30 Интерсепт Фармасьютикалз, Инк. Модуляторы рецептора tgr5 и их применение
ES2663948T3 (es) 2008-11-19 2018-04-17 Intercept Pharmaceuticals, Inc. Moduladores de TGR5 y método de uso de los mismos
NZ734451A (en) 2012-06-19 2018-12-21 Intercept Pharmaceuticals Inc Preparation, uses and solid forms of obeticholic acid
US9982008B2 (en) 2012-06-19 2018-05-29 Intercept Pharmaceuticals, Inc. Preparation and uses of obeticholic acid
US20140206657A1 (en) * 2013-01-18 2014-07-24 City Of Hope Bile acid analog tgr5 agonists

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3997664A (en) * 1971-02-09 1976-12-14 Sandoz, Inc. Substituted carbinol derivatives
US4104285A (en) * 1977-04-22 1978-08-01 Hoffmann-La Roche Inc. Taurine and glycine derivatives
US4117121A (en) * 1977-04-22 1978-09-26 Hoffmann-La Roche Inc. Method of increasing bile flow and decreasing lipid levels
NL8003999A (nl) * 1980-07-11 1982-02-01 Akzo Nv Nieuwe 8 alfa-oestra-1,3,5(10)-trieen-derivaten en de bereiding daarvan.
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
DE3260539D1 (en) * 1981-05-29 1984-09-13 Glaxo Group Ltd 11-alpha-amino-androstanes
ATE8641T1 (de) * 1981-05-29 1984-08-15 Glaxo Group Limited 11-alpha-amino-androstane.
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
DE3366932D1 (en) * 1982-07-29 1986-11-20 Lehner Ag New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same
FR2610933B1 (fr) * 1987-02-18 1989-06-09 Roussel Uclaf Nouveaux 19-nor steroides substitues en position 7, leur preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant

Also Published As

Publication number Publication date
EP0135782A3 (en) 1985-12-11
EP0135782A2 (de) 1985-04-03
JPS6075495A (ja) 1985-04-27
JPH0144197B2 (en) 1989-09-26
IT1212835B (it) 1989-11-30
ES535267A0 (es) 1985-06-16
IT8322572A0 (it) 1983-08-18
US4981983A (en) 1991-01-01
EP0135782B1 (de) 1990-02-28
DE3481419D1 (de) 1990-04-05
ES8506047A1 (es) 1985-06-16

Similar Documents

Publication Publication Date Title
ATE50583T1 (de) Gallensaeure-derivate, verfahren zu ihrer herstellung und pharmazeutische praeparate, die sie enthalten.
NO940277L (no) Triglycerider og blandinger av slike
NL187352C (nl) Farmaceutisch preparaat, alsmede sulfonzuurester van een 2-oxoalkanol derivaat.
NZ189574A (en) Dehydrocyclicimino acid derivatives pharmaceutical compositions
DE3480903D1 (de) Pharmazeutische zusammensetzungen mit gehalt an insulin.
NL191332C (nl) Farmaceutisch preparaat met de ethylester van (all-Z)-5,8,11,14,17-eicosapentaeenzuur.
NL180381C (nl) Werkwijze ter bereiding van een 2-(4-isobutylfenyl)propionzure ester bevattend geneesmiddel en werkwijze ter bereiding van de geneeskrachtige verbindingen.
FI944599L (fi) Kortikoidi-17,21-dikarboksyylihappoesterit sekä kortikosteroidi-17-karboksyylihappoesteri-21-hiilihappoesterit, menetelmä niiden valmistamiseksi ja niitä sisältävät lääkeaineet
NL190806C (nl) Werkwijze ter bereiding van een farmaceutisch preparaat voor de behandeling van acne en werkwijze ter bereiding van een voor opname in een dergelijk preparaat geschikt retinezuurderivaat.
FI793358A7 (fi) Menetelmä vaikeasti sulavan kenodioksikoolihapon valmistamiseksi.
DE2966092D1 (en) Corticoid sulfopropionic acid esters and their salts, process for their preparation and pharmaceutical preparations containing these compounds
EP0328824A3 (en) Sulfonic acid esters useful as sensitizers for positive resists
DE3481512D1 (de) Aroylbenzofuran- und aroylbenzothiophenessigsaeuren und -propionsaeuren, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
AT359197B (de) Verfahren zur herstellung von pharmazeutischen praeparaten
ZA853715B (en) 3,17 beta-estriol diesters,processes for their production,and pharmaceutical preparations containing them
ES455611A1 (es) Metodo de preparar medicamentos basados en acido cenodeoxi- colico y similares.
ZA796048B (en) Phosphonic acid ester derivatives
PT88116A (pt) Process for preparing naphthalenepropionic acid derivatives useful as anti-inflammatory/antiallergic agents
ATE11528T1 (de) Salze der cholsaeuren, verfahren zu ihrer herstellung und therapeutische zusammensetzungen, die sie als aktiven bestandteil enthalten.
JPS559091A (en) Bile acid derivative
ATA437279A (de) Phenanthrenderivate, verfahren zu deren herstellung sowie die phenanthren- derivate enthaltenden pharmazeutischen zusammensetzungen
ATE5650T1 (de) Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung.
ATA697179A (de) Verfahren zur herstellung neuer tricyclischer orthokondensierter stickstoffhaeltiger verbindungen und ihrer pharmazeutischen verwendbaren salze
DE2963782D1 (en) Benzimidazolyl-2-carbamic acid esters, medicaments based thereon and process for their preparation
PT67378B (de) 1-aziridin-carbonsaure-derivate und verfahren zu ihrer herstellung

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee