ATE505224T1 - Vorrichtung mit kontrollierter abgabe und verfahren - Google Patents

Vorrichtung mit kontrollierter abgabe und verfahren

Info

Publication number
ATE505224T1
ATE505224T1 AT03815904T AT03815904T ATE505224T1 AT E505224 T1 ATE505224 T1 AT E505224T1 AT 03815904 T AT03815904 T AT 03815904T AT 03815904 T AT03815904 T AT 03815904T AT E505224 T1 ATE505224 T1 AT E505224T1
Authority
AT
Austria
Prior art keywords
reservoir
caps
reservoirs
contents
substrate
Prior art date
Application number
AT03815904T
Other languages
English (en)
Inventor
Scott Uhland
Benjamin Polito
John Maloney
Norman Sheppard
Stephen Herman
Barry Yomtov
Original Assignee
Microchips Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Microchips Inc filed Critical Microchips Inc
Application granted granted Critical
Publication of ATE505224T1 publication Critical patent/ATE505224T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0082Catheter tip comprising a tool
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/021Measuring pressure in heart or blood vessels
    • A61B5/0215Measuring pressure in heart or blood vessels by means inserted into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/1459Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using optical sensors, e.g. spectral photometrical oximeters invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/25Bioelectric electrodes therefor
    • A61B5/279Bioelectric electrodes therefor specially adapted for particular uses
    • A61B5/28Bioelectric electrodes therefor specially adapted for particular uses for electrocardiography [ECG]
    • A61B5/283Invasive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/48Other medical applications
    • A61B5/4836Diagnosis combined with treatment in closed-loop systems or methods
    • A61B5/4839Diagnosis combined with treatment in closed-loop systems or methods combined with drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/172Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic
    • A61M5/1723Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure
    • A61M2005/1726Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body electrical or electronic using feedback of body parameters, e.g. blood-sugar, pressure the body parameters being measured at, or proximate to, the infusion site
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/02General characteristics of the apparatus characterised by a particular materials
    • A61M2205/0244Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/12General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/123General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with incorporated reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00General characteristics of the apparatus
    • A61M2205/36General characteristics of the apparatus related to heating or cooling
    • A61M2205/3653General characteristics of the apparatus related to heating or cooling by Joule effect, i.e. electric resistance
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/0069Tip not integral with tube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142Pressure infusion, e.g. using pumps
    • A61M5/14244Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M5/14276Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Vascular Medicine (AREA)
  • Medical Informatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
AT03815904T 2002-08-16 2003-08-15 Vorrichtung mit kontrollierter abgabe und verfahren ATE505224T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40419602P 2002-08-16 2002-08-16
US46386503P 2003-04-18 2003-04-18
PCT/US2003/025774 WO2004071487A2 (en) 2002-08-16 2003-08-15 Controlled release device and method

Publications (1)

Publication Number Publication Date
ATE505224T1 true ATE505224T1 (de) 2011-04-15

Family

ID=32871667

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03815904T ATE505224T1 (de) 2002-08-16 2003-08-15 Vorrichtung mit kontrollierter abgabe und verfahren

Country Status (10)

Country Link
US (4) US7510551B2 (de)
EP (1) EP1528940B1 (de)
JP (2) JP4436258B2 (de)
KR (1) KR100725973B1 (de)
CN (1) CN100594892C (de)
AT (1) ATE505224T1 (de)
AU (1) AU2003303288B2 (de)
CA (1) CA2495327C (de)
DE (1) DE60336727D1 (de)
WO (1) WO2004071487A2 (de)

Families Citing this family (134)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7070590B1 (en) 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US6551838B2 (en) * 2000-03-02 2003-04-22 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
DE60139705D1 (de) * 2000-11-09 2009-10-08 Sicel Technologies Inc In-vivo detektion von biomolekülekonzentrationen mittels fluoreszenzmarker
US9107605B2 (en) * 2000-11-17 2015-08-18 Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. Device for in vivo delivery of bioactive agents and method of manufacture thereof
EP1372602B1 (de) 2001-01-09 2007-04-18 Microchips, Inc. Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
DE10234589A1 (de) * 2002-07-30 2004-02-12 Robert Bosch Gmbh Schichtsystem mit einer Siliziumschicht und einer Passivierschicht, Verfahren zur Erzeugung einer Passivierschicht auf einer Siliziumschicht und deren Verwendung
KR100725973B1 (ko) * 2002-08-16 2007-06-11 마이크로칩스 인코포레이티드 전열적 제거를 이용한 제어 방출 장치 및 방법
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
WO2004033036A2 (en) * 2002-10-04 2004-04-22 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
IL152629A (en) * 2002-11-04 2010-12-30 Innoventions Ltd Implantable medical device for controlled release of a substance
WO2005010240A2 (en) * 2003-07-17 2005-02-03 Microchips, Inc. Low temperature methods for hermetically sealing reservoir devices
WO2005016558A2 (en) * 2003-08-04 2005-02-24 Microchips, Inc. Methods for accelerated release of material from a reservoir device
US7169405B2 (en) * 2003-08-06 2007-01-30 Warsaw Orthopedic, Inc. Methods and devices for the treatment of intervertebral discs
US8095197B2 (en) * 2003-11-03 2012-01-10 Microchips, Inc. Medical device for sensing glucose
EP1765455A2 (de) * 2004-06-01 2007-03-28 Microchips, Inc. Vorrichtungen und verfahren zur messung und verstärkung des wirkstoff- oder analyttransports zu/von einem medizinischen implantat
US20070036835A1 (en) * 2004-07-19 2007-02-15 Microchips, Inc. Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents
US7537590B2 (en) * 2004-07-30 2009-05-26 Microchips, Inc. Multi-reservoir device for transdermal drug delivery and sensing
ATE424928T1 (de) * 2004-09-01 2009-03-15 Microchips Inc Behältervorrichtungen mit mehreren verschlüssen zur gesteuerten abgabe oder exponierung des behälterinhalts
US7350479B2 (en) * 2004-09-10 2008-04-01 United States Of America As Represented By The Secretary Of The Army System and method for controlling growth of aquatic plants utilizing bio-eroding means implanted in triploid grass carp
US7156049B2 (en) * 2004-09-10 2007-01-02 The United States Of America As Represented By The Secretary Of The Army Release mechanism to interact with biota, in particular fauna that may outgrow available habitat
GB2418144A (en) * 2004-09-17 2006-03-22 Psimedica Ltd Medical device for delivery of beneficial substance
WO2006050106A1 (en) * 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
EP1861333B1 (de) * 2004-11-04 2018-12-26 Microchips Biotech, Inc. Druck- und kaltschweissdichtverfahren und -vorrichtungen
US7413846B2 (en) 2004-11-15 2008-08-19 Microchips, Inc. Fabrication methods and structures for micro-reservoir devices
EP1843783B1 (de) * 2005-01-25 2012-05-30 MicroCHIPS, Inc. Steuerung der wirkstofffreisetzung mittels transienter modifizierung lokaler mikroumgebungen
WO2006098813A1 (en) * 2005-02-01 2006-09-21 Second Sight Medical Products, Inc. Micro-miniature implantable coated device
US8314024B2 (en) 2008-12-19 2012-11-20 Unity Semiconductor Corporation Device fabrication
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
EP1904146A1 (de) 2005-07-05 2008-04-02 Koninklijke Philips Electronics N.V. Vorrichtung zur kontrollierten freigabe einer vordefinierten menge einer substanz
CN101212994A (zh) 2005-07-05 2008-07-02 皇家飞利浦电子股份有限公司 用于控制释放预定量的物质的设备
US7387813B2 (en) * 2005-07-07 2008-06-17 Specialty Coating Systems, Inc. Methods of preparation of hollow microstructures and nanostructures
US20070228606A1 (en) * 2005-07-07 2007-10-04 Specialty Coating Systems, Inc. Nanoscale structures and methods of preparation
EP1937139A2 (de) * 2005-10-11 2008-07-02 Koninklijke Philips Electronics N.V. Einzeln aktivierte sensoren für implantierbare vorrichtungen
US8273071B2 (en) 2006-01-18 2012-09-25 The Invention Science Fund I, Llc Remote controller for substance delivery system
US8936590B2 (en) * 2005-11-09 2015-01-20 The Invention Science Fund I, Llc Acoustically controlled reaction device
US20070106271A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Remote control of substance delivery system
US8998886B2 (en) * 2005-12-13 2015-04-07 The Invention Science Fund I, Llc Remote control of osmotic pump device
US8992511B2 (en) * 2005-11-09 2015-03-31 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US8083710B2 (en) 2006-03-09 2011-12-27 The Invention Science Fund I, Llc Acoustically controlled substance delivery device
US9474712B2 (en) * 2005-11-09 2016-10-25 Gearbox, Llc In situ reaction device
US20070106277A1 (en) * 2005-11-09 2007-05-10 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Remote controller for substance delivery system
US9067047B2 (en) * 2005-11-09 2015-06-30 The Invention Science Fund I, Llc Injectable controlled release fluid delivery system
US20070148390A1 (en) * 2005-12-27 2007-06-28 Specialty Coating Systems, Inc. Fluorinated coatings
US20070191816A1 (en) * 2006-02-13 2007-08-16 Boston Scientific Scimed, Inc. Radio frequency induced drug elution
US20080140057A1 (en) * 2006-03-09 2008-06-12 Searete Llc, A Limited Liability Corporation Of State Of The Delaware Injectable controlled release fluid delivery system
US7771414B2 (en) * 2006-04-24 2010-08-10 Warsaw Orthopedic, Inc. Controlled release devices for therapeutic treatments of spinal discs
US8642060B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for osteal growth
US8642059B2 (en) * 2006-04-24 2014-02-04 Warsaw Orthopedic, Inc. Controlled release systems and methods for intervertebral discs
US7879027B2 (en) * 2006-04-24 2011-02-01 Warsaw Orthopedic, Inc. Controlled release devices for fusion of osteal structures
CN101438410A (zh) * 2006-05-05 2009-05-20 皇家飞利浦电子股份有限公司 用于可控地释放预定量物质的设备和方法
EP2037999B1 (de) 2006-07-07 2016-12-28 Proteus Digital Health, Inc. Intelligentes parenterales verabreichungssystem
EP2043728A2 (de) * 2006-07-11 2009-04-08 Microchips, Inc. Mehrkammerpumpenvorrichtung für dialyse, biosensing oder verabreichung von substanzen
US20080033260A1 (en) * 2006-08-03 2008-02-07 Microchips, Inc. Cardiac Biosensor Devices and Methods
WO2008029372A2 (en) * 2006-09-08 2008-03-13 Koninklijke Philips Electronics N.V. Device for the controlled release of a predefined quantity of a substance
US8138588B2 (en) * 2006-12-21 2012-03-20 Texas Instruments Incorporated Package stiffener and a packaged device using the same
US7998110B2 (en) * 2007-04-25 2011-08-16 Hong Kong Polytechnic University Medical device for delivering drug and/or performing physical therapy
EP2471457A1 (de) 2007-06-07 2012-07-04 Microchips, Inc. Elektrochemische Biosensoren und Anordnungen
US8366652B2 (en) 2007-08-17 2013-02-05 The Invention Science Fund I, Llc Systems, devices, and methods including infection-fighting and monitoring shunts
US8753304B2 (en) 2007-08-17 2014-06-17 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter
US8702640B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc System, devices, and methods including catheters configured to monitor and inhibit biofilm formation
US8706211B2 (en) 2007-08-17 2014-04-22 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having self-cleaning surfaces
US8734718B2 (en) 2007-08-17 2014-05-27 The Invention Science Fund I, Llc Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component
US9125979B2 (en) * 2007-10-25 2015-09-08 Proteus Digital Health, Inc. Fluid transfer port information system
US8419638B2 (en) * 2007-11-19 2013-04-16 Proteus Digital Health, Inc. Body-associated fluid transport structure evaluation devices
US7833266B2 (en) * 2007-11-28 2010-11-16 Boston Scientific Scimed, Inc. Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment
DE102008024447A1 (de) 2008-05-20 2009-11-26 Biotronik Crm Patent Ag Implantierbare Schockelektrodenleitung und implantierbare Defibrillationsanordnung
WO2009156919A1 (en) * 2008-06-25 2009-12-30 Koninklijke Philips Electronics N.V. Electronic pill comprising a plurality of medicine reservoirs
US7951193B2 (en) * 2008-07-23 2011-05-31 Boston Scientific Scimed, Inc. Drug-eluting stent
WO2010014690A2 (en) * 2008-07-31 2010-02-04 Boston Scientific Scimed, Inc. Medical devices for therapeutic agent delivery
US20110295088A1 (en) 2008-12-04 2011-12-01 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Systems, devices, and methods including implantable devices with anti-microbial properties
EP2384168B1 (de) 2008-12-04 2014-10-08 Searete LLC Aktiv kontrollierbare sterilisierende erregungsabgabe-implantate
US20110208023A1 (en) * 2008-12-04 2011-08-25 Goodall Eleanor V Systems, devices, and methods including implantable devices with anti-microbial properties
US8285387B2 (en) 2008-12-12 2012-10-09 Microchips, Inc. Wireless communication with a medical implant
US8126736B2 (en) 2009-01-23 2012-02-28 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
US8685093B2 (en) 2009-01-23 2014-04-01 Warsaw Orthopedic, Inc. Methods and systems for diagnosing, treating, or tracking spinal disorders
GR1007310B (el) 2009-03-09 2011-06-10 Αχιλλεας Τσουκαλης Εμφυτευσιμος βιοαισθητηρας με αυτοματη βαθμονομηση
EP2416834B1 (de) * 2009-04-07 2013-10-16 Medimetrics Personalized Drug Delivery B.V. Modulare einnehmbare arzneiabgabekapsel
TW201043224A (en) * 2009-06-06 2010-12-16 Univ Nat Taiwan Drug delivery chip and fabricating method thereof
US9283305B2 (en) 2009-07-09 2016-03-15 Medtronic Vascular, Inc. Hollow tubular drug eluting medical devices
JP2013501532A (ja) * 2009-08-08 2013-01-17 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 埋め込み可能なセンサデバイス及びそのようなセンサデバイスに連結可能な医薬送達デバイス
US20110070358A1 (en) 2009-09-20 2011-03-24 Medtronic Vascular, Inc. Method of forming hollow tubular drug eluting medical devices
EP2496936B1 (de) 2009-10-16 2018-02-21 Microchips Biotech, Inc. Mehrkanal-potentiostat für eine biosensoranordnung und verwendungsverfahren
US8696740B2 (en) 2010-01-05 2014-04-15 The Johns Hopkins University Implantable pressure-actuated drug delivery systems and methods of manufacture and use
SG182824A1 (en) 2010-02-01 2012-09-27 Proteus Biomedical Inc Two-wrist data gathering system
WO2011094606A2 (en) 2010-02-01 2011-08-04 Proteus Biomedical, Inc. Data gathering system
US9772261B2 (en) 2010-02-12 2017-09-26 Fluidion Sas Passive micro-vessel and sensor
US9389158B2 (en) 2010-02-12 2016-07-12 Dan Angelescu Passive micro-vessel and sensor
US9869613B2 (en) 2010-02-12 2018-01-16 Fluidion Sas Passive micro-vessel and sensor
BR112012020285B1 (pt) * 2010-02-12 2020-12-29 Dan Angelescu dispositivo, ferramenta, sistema e método para comunicar sua posição por emissão acústica
US10408040B2 (en) 2010-02-12 2019-09-10 Fluidion Sas Passive micro-vessel and sensor
WO2012019083A2 (en) 2010-08-06 2012-02-09 Microchips, Inc. Biosensor membrane composition, biosensor, and methods for making same
WO2012027137A1 (en) * 2010-08-24 2012-03-01 Microchips, Inc. Implantable biosensor device and methods of use thereof
US9289584B2 (en) 2010-09-13 2016-03-22 The University Of British Columbia Remotely controlled drug delivery systems
JP6117788B2 (ja) 2011-08-25 2017-04-19 マイクロチップス バイオテック,インコーポレイテッド 空間効率的な封じ込めデバイスおよびこれを作成する方法
US10427153B2 (en) 2011-08-25 2019-10-01 Microchips Biotech, Inc. Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid
EP2774207B1 (de) 2011-11-03 2019-07-03 Robert Bosch GmbH Lithiumionenbatterie mit einem lebensdauerverlängernden additiv
BR112014020186A8 (pt) 2012-02-22 2017-07-11 Duchesnay Inc Formulação de doxilamina e piridoxina e/ou seus metabólitos ou sais
SG193127A1 (en) * 2012-02-29 2013-09-30 Johnson & Johnson Vision Care Punctal plug with energized containment array
SG11201504886SA (en) 2012-12-21 2015-07-30 Microchips Biotech Inc Implantable medical device for minimally-invasive insertion
WO2014122221A1 (en) 2013-02-06 2014-08-14 Dan Angelescu Passive micro-vessel and sensor
EP2953542A4 (de) 2013-02-06 2016-10-05 California Inst Of Techn Miniaturisierte implantierbare elektrochemische sensoren
JP6387357B2 (ja) 2013-02-28 2018-09-05 マイクロチップス バイオテック,インコーポレイテッド 低侵襲挿入のための植え込み型医療デバイス
US9486340B2 (en) 2013-03-14 2016-11-08 Medtronic Vascular, Inc. Method for manufacturing a stent and stent manufactured thereby
AU2014274061C1 (en) * 2013-05-31 2019-06-13 Mannkind Corporation A fluid delivery device having an insertable prefilled cartridge
EP3024466B1 (de) 2013-07-22 2018-04-04 Duchesnay Inc. Zusammensetzung zur behandlung von übelkeit und erbrechen
EP3030286B1 (de) 2013-08-05 2019-10-09 Cam Med LLC Anschmiegbare patch pumpe
WO2015150429A2 (en) 2014-04-03 2015-10-08 Fluidion Passive micro-vessel and sensor
RU2677538C2 (ru) * 2014-04-25 2019-01-17 Джонсон Энд Джонсон Вижн Кэа, Инк. Способ и офтальмологическое устройство с системой высвобождения активного агента
US10350349B2 (en) 2014-05-20 2019-07-16 Cequr Sa Medicine delivery device with restricted access filling port
US10244951B2 (en) * 2014-06-10 2019-04-02 Acist Medical Systems, Inc. Physiological sensor delivery device and method
US9937124B2 (en) 2014-09-11 2018-04-10 International Business Machines Corporation Microchip substance delivery devices having low-power electromechanical release mechanisms
US9808608B2 (en) 2014-11-16 2017-11-07 International Business Machines Corporation Helical coil delivery device for active agent
US10820844B2 (en) 2015-07-23 2020-11-03 California Institute Of Technology Canary on a chip: embedded sensors with bio-chemical interfaces
US10881788B2 (en) 2015-10-30 2021-01-05 International Business Machines Corporation Delivery device including reactive material for programmable discrete delivery of a substance
US9672393B1 (en) * 2016-02-01 2017-06-06 Verily Life Sciences, LLC Phase controlled array for wirelessly powering implantable devices
US10286198B2 (en) 2016-04-08 2019-05-14 International Business Machines Corporation Microchip medical substance delivery devices
US11172879B2 (en) 2016-05-09 2021-11-16 King Abdullah University Of Science And Technology Wearable personalized medicinal platform
US10620151B2 (en) 2016-08-30 2020-04-14 Analog Devices Global Electrochemical sensor, and a method of forming an electrochemical sensor
US11268927B2 (en) 2016-08-30 2022-03-08 Analog Devices International Unlimited Company Electrochemical sensor, and a method of forming an electrochemical sensor
US12188893B2 (en) 2016-08-30 2025-01-07 Analog Devices International Unlimited Company Electrochemical sensor, and a method of forming an electrochemical sensor
US10784877B2 (en) 2016-12-21 2020-09-22 Johnson & Johnson Vision Care, Inc. Extended period timer circuits for ophthalmic devices
US10737090B2 (en) 2017-07-11 2020-08-11 Medtronic, Inc. External defibrillation electrode conductive electrolyte dispersal pad
US10508755B2 (en) * 2017-07-21 2019-12-17 International Business Machines Corporation Fluid delivery device with hydrophobic surface
WO2019138108A1 (en) 2018-01-15 2019-07-18 Fluidion Passive micro-vessel and sensor
US11022579B2 (en) 2018-02-05 2021-06-01 Analog Devices International Unlimited Company Retaining cap
GB201807489D0 (en) * 2018-05-08 2018-06-20 Sentinel Subsea Ltd Apparatus and method
US20210330901A1 (en) * 2018-09-23 2021-10-28 Douglas G. Metcalf Systems and Methods to Administer Pharmaceuticals
WO2020107127A1 (en) * 2018-11-30 2020-06-04 Ma Joseph J K Ocular systems, devices, and methods
CA3126275A1 (en) 2019-01-09 2020-07-16 Twenty Twenty Therapeutics Llc Programmable therapeutic agent delivery from eye mounted device
WO2020146362A1 (en) 2019-01-09 2020-07-16 Verily Life Sciences Llc Eye mounted device for therapeutic agent release
US11406299B2 (en) * 2019-02-22 2022-08-09 International Business Machines Corporation Biosensors with programmable sensing cavities
KR20220091506A (ko) 2019-11-01 2022-06-30 데어 엠비 아이엔씨. 2단계 마이크로칩 약물 전달 장치 및 방법
EP4275593A1 (de) * 2022-05-09 2023-11-15 Wellspect AB Medizinische wegwerfvorrichtungsanordnung mit sensor
CN117228133A (zh) * 2022-06-15 2023-12-15 珠海纳思达信息技术有限公司 包装件、包装组件和数据存储部的升级方法

Family Cites Families (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692027A (en) * 1971-04-23 1972-09-19 Everett H Ellinwood Jr Implanted medication dispensing device and method
DE2505186C3 (de) * 1974-02-15 1979-07-12 N.V. Philips' Gloeilampenfabrieken, Eindhoven (Niederlande) Programmierbarer Lesespeicher
US4003379A (en) * 1974-04-23 1977-01-18 Ellinwood Jr Everett H Apparatus and method for implanted self-powered medication dispensing
US4146029A (en) * 1974-04-23 1979-03-27 Ellinwood Jr Everett H Self-powered implanted programmable medication system and method
US4089734A (en) * 1974-09-16 1978-05-16 Raytheon Company Integrated circuit fusing technique
US3952741A (en) * 1975-01-09 1976-04-27 Bend Research Inc. Controlled release delivery system by an osmotic bursting mechanism
US4209894A (en) * 1978-04-27 1980-07-01 Texas Instruments Incorporated Fusible-link semiconductor memory
US4345981A (en) * 1978-11-24 1982-08-24 Diamond Shamrock Corporation Anodically polarized surface for biofouling and scale control
US4360019A (en) * 1979-02-28 1982-11-23 Andros Incorporated Implantable infusion device
GB8422876D0 (en) * 1984-09-11 1984-10-17 Secr Defence Silicon implant devices
US4585652A (en) * 1984-11-19 1986-04-29 Regents Of The University Of Minnesota Electrochemical controlled release drug delivery system
US5252294A (en) * 1988-06-01 1993-10-12 Messerschmitt-Bolkow-Blohm Gmbh Micromechanical structure
US5200051A (en) * 1988-11-14 1993-04-06 I-Stat Corporation Wholly microfabricated biosensors and process for the manufacture and use thereof
US5041107A (en) * 1989-10-06 1991-08-20 Cardiac Pacemakers, Inc. Electrically controllable, non-occluding, body implantable drug delivery system
US5167625A (en) * 1990-10-09 1992-12-01 Sarcos Group Multiple vesicle implantable drug delivery system
US5493177A (en) * 1990-12-03 1996-02-20 The Regents Of The University Of California Sealed micromachined vacuum and gas filled devices
US5254081A (en) * 1991-02-01 1993-10-19 Empi, Inc. Multiple site drug iontophoresis electronic device and method
US5391164A (en) * 1991-05-03 1995-02-21 Giampapa; Vincent C. Subcutaneous implantable multiple-agent delivery system
US5605662A (en) * 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5533995A (en) * 1991-11-13 1996-07-09 Elan Corporation, Plc Passive transdermal device with controlled drug delivery
US5756117A (en) * 1992-04-08 1998-05-26 International Medical Asscociates, Inc. Multidose transdermal drug delivery system
US5304293A (en) * 1992-05-11 1994-04-19 Teknekron Sensor Development Corporation Microsensors for gaseous and vaporous species
US5380272A (en) * 1993-01-28 1995-01-10 Scientific Innovations Ltd. Transcutaneous drug delivery applicator
US5368588A (en) * 1993-02-26 1994-11-29 Bettinger; David S. Parenteral fluid medication reservoir pump
US5366454A (en) * 1993-03-17 1994-11-22 La Corporation De L'ecole Polytechnique Implantable medication dispensing device
US5368704A (en) * 1993-08-06 1994-11-29 Teknekron Corporation Micro-electrochemical valves and method
US6180239B1 (en) * 1993-10-04 2001-01-30 President And Fellows Of Harvard College Microcontact printing on surfaces and derivative articles
JP3488465B2 (ja) 1993-10-28 2004-01-19 ヒューストン・アドバンスド・リサーチ・センター 結合反応を別々に検出する微細加工フロースルー多孔性装置
US6129685A (en) * 1994-02-09 2000-10-10 The University Of Iowa Research Foundation Stereotactic hypothalamic obesity probe
US5770076A (en) * 1994-03-07 1998-06-23 The Regents Of The University Of California Micromachined capsules having porous membranes and bulk supports
US5985328A (en) * 1994-03-07 1999-11-16 Regents Of The University Of California Micromachined porous membranes with bulk support
US5660680A (en) * 1994-03-07 1997-08-26 The Regents Of The University Of California Method for fabrication of high vertical aspect ratio thin film structures
US5971931A (en) * 1994-03-29 1999-10-26 Raff; Gilbert Lewis Biologic micromonitoring methods and systems
US5585069A (en) * 1994-11-10 1996-12-17 David Sarnoff Research Center, Inc. Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis
US5504026A (en) * 1995-04-14 1996-04-02 Analog Devices, Inc. Methods for planarization and encapsulation of micromechanical devices in semiconductor processes
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
US5992769A (en) * 1995-06-09 1999-11-30 The Regents Of The University Of Michigan Microchannel system for fluid delivery
SE9502258D0 (sv) * 1995-06-21 1995-06-21 Pharmacia Biotech Ab Method for the manufacture of a membrane-containing microstructure
US6518168B1 (en) * 1995-08-18 2003-02-11 President And Fellows Of Harvard College Self-assembled monolayer directed patterning of surfaces
US5662689A (en) * 1995-09-08 1997-09-02 Medtronic, Inc. Method and apparatus for alleviating cardioversion shock pain
WO1997029802A2 (en) * 1996-02-20 1997-08-21 Advanced Bionics Corporation Improved implantable microstimulator and systems employing the same
DE19610293C1 (de) * 1996-03-15 1997-07-31 Fraunhofer Ges Forschung Vorrichtung zur gekapselten Aufnahme eines Materials
US5951881A (en) * 1996-07-22 1999-09-14 President And Fellows Of Harvard College Fabrication of small-scale cylindrical articles
US5824204A (en) * 1996-06-27 1998-10-20 Ic Sensors, Inc. Micromachined capillary electrophoresis device
US7070590B1 (en) * 1996-07-02 2006-07-04 Massachusetts Institute Of Technology Microchip drug delivery devices
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
US6136212A (en) * 1996-08-12 2000-10-24 The Regents Of The University Of Michigan Polymer-based micromachining for microfluidic devices
IN184589B (de) * 1996-10-16 2000-09-09 Alza Corp
US6326204B1 (en) * 1997-01-17 2001-12-04 Maxygen, Inc. Evolution of whole cells and organisms by recursive sequence recombination
DE19716683C1 (de) 1997-04-21 1998-06-04 Fraunhofer Ges Forschung Vorrichtung zur getrennten, gekapselten Aufnahme einer Mehrzahl gleicher oder unterschiedlicher Stoffe
AU727083B2 (en) * 1997-04-25 2000-11-30 Caliper Life Sciences, Inc. Microfluidic devices incorporating improved channel geometries
IL121286A0 (en) * 1997-07-11 1998-01-04 Pets N People Ltd Apparatus and methods for dispensing pet care substances
US5949187A (en) * 1997-07-29 1999-09-07 Motorola, Inc. Organic electroluminescent device with plural microcavities
US5961492A (en) * 1997-08-27 1999-10-05 Science Incorporated Fluid delivery device with temperature controlled energy source
US5842787A (en) * 1997-10-09 1998-12-01 Caliper Technologies Corporation Microfluidic systems incorporating varied channel dimensions
US6081736A (en) * 1997-10-20 2000-06-27 Alfred E. Mann Foundation Implantable enzyme-based monitoring systems adapted for long term use
US6486588B2 (en) 1997-12-30 2002-11-26 Remon Medical Technologies Ltd Acoustic biosensor for monitoring physiological conditions in a body implantation site
US6140740A (en) * 1997-12-30 2000-10-31 Remon Medical Technologies, Ltd. Piezoelectric transducer
US6475170B1 (en) 1997-12-30 2002-11-05 Remon Medical Technologies Ltd Acoustic biosensor for monitoring physiological conditions in a body implantation site
US6237398B1 (en) * 1997-12-30 2001-05-29 Remon Medical Technologies, Ltd. System and method for monitoring pressure, flow and constriction parameters of plumbing and blood vessels
US6001090A (en) 1998-02-09 1999-12-14 Lenhart; Douglas Thermal pharmaceutical delivery system
US6027695A (en) * 1998-04-01 2000-02-22 Dupont Pharmaceuticals Company Apparatus for holding small volumes of liquids
US6757560B1 (en) * 1999-04-09 2004-06-29 Novosis Pharma Ag Transdermal delivery system (TDS) with electrode network
US6161047A (en) 1998-04-30 2000-12-12 Medtronic Inc. Apparatus and method for expanding a stimulation lead body in situ
US6319241B1 (en) * 1998-04-30 2001-11-20 Medtronic, Inc. Techniques for positioning therapy delivery elements within a spinal cord or a brain
US6062461A (en) * 1998-06-03 2000-05-16 Delphi Technologies, Inc. Process for bonding micromachined wafers using solder
US6058752A (en) * 1998-06-10 2000-05-09 Feder; George N. Pick-resistant lock system and method
US6941171B2 (en) * 1998-07-06 2005-09-06 Advanced Bionics Corporation Implantable stimulator methods for treatment of incontinence and pain
US6908770B1 (en) * 1998-07-16 2005-06-21 Board Of Regents, The University Of Texas System Fluid based analysis of multiple analytes by a sensor array
US6201980B1 (en) * 1998-10-05 2001-03-13 The Regents Of The University Of California Implantable medical sensor system
US6232150B1 (en) * 1998-12-03 2001-05-15 The Regents Of The University Of Michigan Process for making microstructures and microstructures made thereby
US6289237B1 (en) * 1998-12-22 2001-09-11 University Of Pittsburgh Of The Commonwealth System Of Higher Education Apparatus for energizing a remote station and related method
US6171850B1 (en) * 1999-03-08 2001-01-09 Caliper Technologies Corp. Integrated devices and systems for performing temperature controlled reactions and analyses
US6178349B1 (en) * 1999-04-15 2001-01-23 Medtronic, Inc. Drug delivery neural stimulation device for treatment of cardiovascular disorders
US6669663B1 (en) * 1999-04-30 2003-12-30 Medtronic, Inc. Closed loop medicament pump
US6923784B2 (en) * 1999-04-30 2005-08-02 Medtronic, Inc. Therapeutic treatment of disorders based on timing information
US6683615B1 (en) * 1999-06-09 2004-01-27 3Dlabs Inc., Ltd. Doubly-virtualized texture memory
US6587719B1 (en) * 1999-07-01 2003-07-01 Cyberonics, Inc. Treatment of obesity by bilateral vagus nerve stimulation
US6804558B2 (en) * 1999-07-07 2004-10-12 Medtronic, Inc. System and method of communicating between an implantable medical device and a remote computer system or health care provider
US6334859B1 (en) * 1999-07-26 2002-01-01 Zuli Holdings Ltd. Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments
DE60018582T2 (de) * 1999-08-18 2006-01-19 Microchips, Inc., Bedford Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien
JP2003513755A (ja) * 1999-11-17 2003-04-15 マイクロチップス・インコーポレーテッド キャリア流体内への分子の送達のための微細加工されたデバイス
JP2003516343A (ja) 1999-12-10 2003-05-13 マサチューセッツ インスティテュート オブ テクノロジー 分子を送達するマイクロチップ素子およびその製作方法
CN2414777Y (zh) * 1999-12-14 2001-01-17 陈刚 透皮渗药仪
US6384353B1 (en) * 2000-02-01 2002-05-07 Motorola, Inc. Micro-electromechanical system device
US6551838B2 (en) * 2000-03-02 2003-04-22 Microchips, Inc. Microfabricated devices for the storage and selective exposure of chemicals and devices
AU2001265128A1 (en) * 2000-05-30 2001-12-11 Massachusetts Institute Of Technology Methods and devices for sealing microchip reservoir devices
CN2460122Y (zh) * 2000-06-19 2001-11-21 翁春晓 一种超声电导透皮给药装置的治疗头
WO2002013785A2 (en) * 2000-08-14 2002-02-21 Pharmacia Corporation Drug delivery system with burst electrode
US6437640B1 (en) * 2000-09-12 2002-08-20 The Aerospace Corporation Addressable diode isolated thin film array
US6403403B1 (en) * 2000-09-12 2002-06-11 The Aerospace Corporation Diode isolated thin film fuel cell array addressing method
EP1339312B1 (de) * 2000-10-10 2006-01-04 Microchips, Inc. Mikrochip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten
US6773429B2 (en) * 2000-10-11 2004-08-10 Microchips, Inc. Microchip reservoir devices and facilitated corrosion of electrodes
EP1339451B1 (de) * 2000-10-26 2009-09-30 Medtronic, Inc. Vorrichtung zur minimierung der wirkungen eines herzinsults
WO2002045791A2 (en) * 2000-10-26 2002-06-13 Medtronic, Inc. Method and apparatus for electrically stimulating the nervous system to improve ventricular dysfunction, heart failure, and other cardiac comditions
WO2002034327A2 (en) * 2000-10-26 2002-05-02 Medtronic, Inc. Method and apparatus to minimize the effects of a cardiac insult
US6378292B1 (en) * 2000-11-10 2002-04-30 Honeywell International Inc. MEMS microthruster array
DE10061057A1 (de) * 2000-12-08 2002-06-13 Pharmed Holding Gmbh Chip-Systeme zur kontrollierten Emission chemosensorisch wirkender Stoffe
DE10063612C2 (de) 2000-12-20 2002-11-07 Fraunhofer Ges Forschung Mikrosystem zur Kontrolle der Wirkstoffabgabe aus einem Wirkstoffreservoir sowie Implantat mit Mikrosystem
EP1372602B1 (de) 2001-01-09 2007-04-18 Microchips, Inc. Flexible mikrochip-vorrichtungen zur ophthalmologischen und anderen applikation
WO2002056940A2 (en) * 2001-01-22 2002-07-25 Integrated Sensing Systems, Inc. Sensing catheter system and method of fabrication
DE10102817B4 (de) 2001-01-23 2006-01-12 Lts Lohmann Therapie-Systeme Ag Vorrichtung und Verfahren zur Hitzepulsgestützten transdermalen Applikation von Wirkstoffen
US6571125B2 (en) * 2001-02-12 2003-05-27 Medtronic, Inc. Drug delivery device
US7181287B2 (en) 2001-02-13 2007-02-20 Second Sight Medical Products, Inc. Implantable drug delivery device
US6858220B2 (en) * 2001-02-28 2005-02-22 Second Sight Medical Products, Inc. Implantable microfluidic delivery system using ultra-nanocrystalline diamond coating
US20020144548A1 (en) * 2001-04-06 2002-10-10 Cohn Michael B. High precision accelerometer
WO2002089767A1 (en) * 2001-05-03 2002-11-14 Massachusetts Eye And Ear Infirmary Implantable drug delivery device and use thereof
US6733485B1 (en) * 2001-05-25 2004-05-11 Advanced Bionics Corporation Microstimulator-based electrochemotherapy methods and systems
EP1395335A1 (de) * 2001-05-29 2004-03-10 Medtronic, Inc. Neuromodulation mit geschlossenem regelkreis zur verhinderung und behandlung von herzzuständen
WO2002096389A1 (en) 2001-05-30 2002-12-05 Microchips, Inc. Conformal coated microchip reservoir devices
AU2002326304A1 (en) 2001-05-31 2002-12-16 Massachusetts Institute Of Technology Microchip devices with improved reservoir opening
US6827250B2 (en) 2001-06-28 2004-12-07 Microchips, Inc. Methods for hermetically sealing microchip reservoir devices
CA2451580A1 (en) * 2001-06-29 2003-01-09 The Board Of Trustees Of The Leland Stanford Junior University Artificial synapse chip interface for electronic prosthetic retina
US6663615B1 (en) 2001-09-04 2003-12-16 The Ohio State University Dual stage microvalve and method of use
US7097775B2 (en) * 2001-10-26 2006-08-29 Second Sight Medical Products, Inc. Coated microfluidic delivery system
KR100725973B1 (ko) * 2002-08-16 2007-06-11 마이크로칩스 인코포레이티드 전열적 제거를 이용한 제어 방출 장치 및 방법
WO2004022033A1 (en) * 2002-09-04 2004-03-18 Microchips, Inc. Method and device for the controlled delivery of parathyroid hormone
AU2003284018A1 (en) * 2002-10-04 2004-05-04 Microchips, Inc. Medical device for neural stimulation and controlled drug delivery
WO2004033036A2 (en) * 2002-10-04 2004-04-22 Microchips, Inc. Medical device for controlled drug delivery and cardiac monitoring and/or stimulation
WO2004096176A2 (en) 2003-04-25 2004-11-11 Boston Scientific Scimed Inc. Solid drug formulation and device for storage and controlled delivery thereof
KR20140134338A (ko) * 2003-09-11 2014-11-21 테라노스, 인코포레이티드 피분석물의 모니터링 및 약물 전달을 위한 의료 기기

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CA2495327C (en) 2008-10-21
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