ATE495175T1 - Naphthyridinderivate als kaliumkanalmodulatoren - Google Patents

Naphthyridinderivate als kaliumkanalmodulatoren

Info

Publication number
ATE495175T1
ATE495175T1 AT08796974T AT08796974T ATE495175T1 AT E495175 T1 ATE495175 T1 AT E495175T1 AT 08796974 T AT08796974 T AT 08796974T AT 08796974 T AT08796974 T AT 08796974T AT E495175 T1 ATE495175 T1 AT E495175T1
Authority
AT
Austria
Prior art keywords
potassium channel
channel modulators
naphthyridine derivatives
compound
naphthyridine
Prior art date
Application number
AT08796974T
Other languages
English (en)
Inventor
Jean-Michel Vernier
Original Assignee
Valeant Pharmaceuticals International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeant Pharmaceuticals International Inc filed Critical Valeant Pharmaceuticals International Inc
Application granted granted Critical
Publication of ATE495175T1 publication Critical patent/ATE495175T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Liquid Crystal Substances (AREA)
  • Pyridine Compounds (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT08796974T 2007-08-01 2008-07-31 Naphthyridinderivate als kaliumkanalmodulatoren ATE495175T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96286207P 2007-08-01 2007-08-01
US12/181,126 US8563566B2 (en) 2007-08-01 2008-07-28 Naphthyridine derivatives as potassium channel modulators
PCT/US2008/071803 WO2009018466A1 (en) 2007-08-01 2008-07-31 Naphthyridine derivatives as potassium channel modulators

Publications (1)

Publication Number Publication Date
ATE495175T1 true ATE495175T1 (de) 2011-01-15

Family

ID=39865205

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08796974T ATE495175T1 (de) 2007-08-01 2008-07-31 Naphthyridinderivate als kaliumkanalmodulatoren

Country Status (15)

Country Link
US (1) US8563566B2 (de)
EP (2) EP2183250B1 (de)
JP (1) JP2010535244A (de)
KR (1) KR20100068373A (de)
CN (1) CN101778848A (de)
AT (1) ATE495175T1 (de)
AU (1) AU2008282118A1 (de)
BR (1) BRPI0814893A2 (de)
CA (1) CA2695196A1 (de)
DE (1) DE602008004555D1 (de)
MX (1) MX2010001189A (de)
PL (1) PL2183250T3 (de)
RU (1) RU2481347C2 (de)
TW (1) TW200922571A (de)
WO (1) WO2009018466A1 (de)

Families Citing this family (25)

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US8722929B2 (en) * 2006-10-10 2014-05-13 Valeant Pharmaceuticals International N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators
US8367684B2 (en) * 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
US8563566B2 (en) 2007-08-01 2013-10-22 Valeant Pharmaceuticals International Naphthyridine derivatives as potassium channel modulators
US7786146B2 (en) * 2007-08-13 2010-08-31 Valeant Pharmaceuticals International Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators
TWI504395B (zh) 2009-03-10 2015-10-21 Substituted 3-amino-2-mercaptoquinoline as a KCNQ2 / 3 modifier
TWI461197B (zh) 2009-03-12 2014-11-21 2-mercaptoquinoline-3-carboxamide as a KCNQ2 / 3 modifier
TW201038565A (en) * 2009-03-12 2010-11-01 Gruenenthal Gmbh Substituted 2-mercapto-3-aminopyridines as KCNQ2/3 modulators
TWI475020B (zh) 2009-03-12 2015-03-01 The substituted nicotine amide as a KCNQ2 / 3 modifier
US20120115900A1 (en) 2009-04-21 2012-05-10 Neurosearch A/S Substituted naphthyridine derivatives and their medical use
AR082732A1 (es) 2010-08-27 2012-12-26 Gruenenthal Gmbh 2-oxiquinolina-3-carboxamidas sustituidas como moduladores de kcnq2/3
WO2012025237A1 (en) 2010-08-27 2012-03-01 Grünenthal GmbH Substituted 2-amino-quinoline-3-carboxamides as kcnq2/3 modulators
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Also Published As

Publication number Publication date
DE602008004555D1 (de) 2011-02-24
EP2183250B1 (de) 2011-01-12
US20090170885A1 (en) 2009-07-02
US8563566B2 (en) 2013-10-22
PL2183250T3 (pl) 2011-06-30
EP2183250A1 (de) 2010-05-12
JP2010535244A (ja) 2010-11-18
EP2311836A1 (de) 2011-04-20
CA2695196A1 (en) 2009-02-05
CN101778848A (zh) 2010-07-14
MX2010001189A (es) 2010-08-10
TW200922571A (en) 2009-06-01
RU2481347C2 (ru) 2013-05-10
RU2010107284A (ru) 2011-09-10
KR20100068373A (ko) 2010-06-23
BRPI0814893A2 (pt) 2015-09-15
WO2009018466A1 (en) 2009-02-05
AU2008282118A1 (en) 2009-02-05

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