ATE491030T1 - Rekombinante expression von rubella e1 hüllenproteinvarianten als chaperon- fusionsproteine und seine verwendung zum nachweis von anti-rubella antikörper - Google Patents

Rekombinante expression von rubella e1 hüllenproteinvarianten als chaperon- fusionsproteine und seine verwendung zum nachweis von anti-rubella antikörper

Info

Publication number
ATE491030T1
ATE491030T1 AT06022216T AT06022216T ATE491030T1 AT E491030 T1 ATE491030 T1 AT E491030T1 AT 06022216 T AT06022216 T AT 06022216T AT 06022216 T AT06022216 T AT 06022216T AT E491030 T1 ATE491030 T1 AT E491030T1
Authority
AT
Austria
Prior art keywords
rubella
antibodies
detection
fusion proteins
recombinant expression
Prior art date
Application number
AT06022216T
Other languages
German (de)
English (en)
Inventor
Ralf Bollhagen
Alfred Engel
Elke Faatz
Peter Schaarschmidt
Christian Scholz
Barbara Upmeier
Toralf Zarnt
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE491030T1 publication Critical patent/ATE491030T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/35Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/36011Togaviridae
    • C12N2770/36211Rubivirus, e.g. rubella virus
    • C12N2770/36222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82Proteins from microorganisms
    • Y10S530/826Viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06022216T 2005-10-26 2006-10-24 Rekombinante expression von rubella e1 hüllenproteinvarianten als chaperon- fusionsproteine und seine verwendung zum nachweis von anti-rubella antikörper ATE491030T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05109993 2005-10-26

Publications (1)

Publication Number Publication Date
ATE491030T1 true ATE491030T1 (de) 2010-12-15

Family

ID=37965193

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06022216T ATE491030T1 (de) 2005-10-26 2006-10-24 Rekombinante expression von rubella e1 hüllenproteinvarianten als chaperon- fusionsproteine und seine verwendung zum nachweis von anti-rubella antikörper

Country Status (6)

Country Link
US (1) US7604935B2 (enExample)
JP (1) JP4116054B2 (enExample)
AT (1) ATE491030T1 (enExample)
CA (1) CA2562738C (enExample)
DE (1) DE602006018694D1 (enExample)
ES (1) ES2356383T3 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1971684B1 (en) * 2006-01-03 2011-10-05 Roche Diagnostics GmbH Chimaeric fusion protein with superior chaperone and folding activities
WO2009018500A1 (en) * 2007-07-31 2009-02-05 The Johns Hopkins University Polypeptide-nucleic acid conjugate for immunoprophylaxis or immunotherapy for neoplastic or infectious disorders
WO2009074318A2 (en) * 2007-12-13 2009-06-18 Roche Diagnostics Gmbh Novel rubella e1 envelope protein variants and their use in the detection of anti-rubella antibodies
AR086250A1 (es) * 2011-05-05 2013-11-27 Hoffmann La Roche Polipeptido de fusion presentador de una secuencia de aminoacidos y utilizacion del mismo

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2095818B (en) 1981-03-27 1985-10-02 Exxon Research Engineering Co Staged adsorption/resorption heat pump
EP0299673A1 (en) 1987-07-08 1989-01-18 London Biotechnology Limited Rubella E1 glycoprotein antigens
WO1998013496A1 (en) 1996-09-26 1998-04-02 Medical Research Council Chaperone fragments
DE19649390A1 (de) 1996-11-29 1998-06-04 Boehringer Mannheim Gmbh Antigenspezifischer IgG-Nachweis
KR100702373B1 (ko) 2001-06-22 2007-04-02 에프. 호프만-라 로슈 아게 레트로바이러스 표면 당단백질을 함유하는 가용성 복합체

Also Published As

Publication number Publication date
JP4116054B2 (ja) 2008-07-09
US7604935B2 (en) 2009-10-20
CA2562738C (en) 2011-07-12
JP2007117090A (ja) 2007-05-17
ES2356383T3 (es) 2011-04-07
CA2562738A1 (en) 2007-04-26
DE602006018694D1 (de) 2011-01-20
US20070154883A1 (en) 2007-07-05

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