ATE490764T1 - Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung - Google Patents

Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung

Info

Publication number
ATE490764T1
ATE490764T1 AT03798655T AT03798655T ATE490764T1 AT E490764 T1 ATE490764 T1 AT E490764T1 AT 03798655 T AT03798655 T AT 03798655T AT 03798655 T AT03798655 T AT 03798655T AT E490764 T1 ATE490764 T1 AT E490764T1
Authority
AT
Austria
Prior art keywords
core
opening
sustained release
release pharmaceutical
pharmaceutical forms
Prior art date
Application number
AT03798655T
Other languages
English (en)
Inventor
Harry Sowden
Gerard Mcnally
David Wynn
Oliver Anderson
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/031163 external-priority patent/WO2003026627A1/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Application granted granted Critical
Publication of ATE490764T1 publication Critical patent/ATE490764T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893—Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT03798655T 2002-09-28 2003-03-21 Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung ATE490764T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PCT/US2002/031163 WO2003026627A1 (en) 2001-09-28 2002-09-28 Composite dosage forms
PCT/US2002/031024 WO2003026625A1 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2002/031117 WO2003026629A2 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2002/031129 WO2003026630A1 (en) 2001-09-28 2002-09-28 Dosage forms having an inner core and outer shell with different shapes
PCT/US2002/031062 WO2003026626A2 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2003/008894 WO2004028508A1 (en) 2002-09-28 2003-03-21 Modified release dosage forms with two cores and an opening

Publications (1)

Publication Number Publication Date
ATE490764T1 true ATE490764T1 (de) 2010-12-15

Family

ID=32046115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03798655T ATE490764T1 (de) 2002-09-28 2003-03-21 Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung

Country Status (8)

Country Link
EP (6) EP1542661B1 (de)
KR (3) KR100995486B1 (de)
AT (1) ATE490764T1 (de)
CA (4) CA2499882C (de)
ES (1) ES2355233T3 (de)
NZ (1) NZ538842A (de)
RU (5) RU2005108577A (de)
WO (7) WO2004028510A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
CN102525993B (zh) 2003-04-24 2017-04-12 佳高泰克有限公司 具有限定内核几何形状的缓释片剂
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
NZ588372A (en) * 2005-09-09 2012-03-30 Novartis Ag Diphenyl ether or thioether derivatives for treatment of autoimmune diseases
DE602007008384D1 (de) * 2006-03-28 2010-09-23 Mcneil Ppc Inc Formbeschichtungen mit ungleichmässiger dosierung
CN101374497A (zh) * 2006-05-08 2009-02-25 麦克内尔-Ppc股份有限公司 渗透剂型
SG174026A1 (en) 2006-08-03 2011-09-29 Nitec Pharma Ag Delayed-release glucocorticoid treatment of rheumatoid disease
US20080075766A1 (en) * 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
US20110195121A1 (en) * 2008-06-19 2011-08-11 Seshni Sewlall chronotherapeutic pharmaceutical dosage form
JP5912126B2 (ja) * 2010-11-26 2016-04-27 ユニバーシティ・オブ・ジ・ウィトウォーターズランド・ヨハネスブルクUniversity Of The Witwatersrand, Johannesburg 医薬投与形態
WO2013009701A2 (en) 2011-07-08 2013-01-17 The University Of North Carolina At Chapel Hill Metal bisphosphonate nanoparticles for anti-cancer therapy and imaging and for treating bone disorders
CN105873569B (zh) 2013-11-06 2020-07-28 芝加哥大学 用于化疗剂、核酸和光敏剂的递送或共递送的纳米级载体
US11246877B2 (en) 2016-05-20 2022-02-15 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
WO2019028250A1 (en) 2017-08-02 2019-02-07 The University Of Chicago NOMOGENEOUS ORGANOMETALLIC ORGANOMETRIC ORGANOMETRIC LAYERS FOR X-RAY INDUCED PHOTODYNAMIC THERAPY, RADIOTHERAPY, RODIODYNAMIC THERAPY, CHEMOTHERAPY, IMMUNOTHERAPY, AND ANY COMBINATION THEREOF
WO2019129360A1 (en) * 2017-12-29 2019-07-04 Laxxon Medical Ag Drug delivery system
EP3810111A4 (de) * 2018-06-19 2022-03-23 National University of Singapore Formulierungen von 5-hydroxytryptophan (5-htp) zur besseren bioverfügbarkeit für verschiedene indikationen
CN111529548B (zh) * 2020-05-13 2022-07-26 上海美农生物科技股份有限公司 肠溶氧化锌颗粒
KR102651137B1 (ko) * 2021-01-08 2024-03-22 김주봉 성기능 개선을 위한 건강보조식품용 환의 제조방법
US12409163B2 (en) * 2021-07-30 2025-09-09 Evecxia Therapeutics, Inc. Method of enhancing 5-hydroxytryptophan (5-HTP) exposure
JP2024528125A (ja) * 2021-07-30 2024-07-26 エヴェクシア セラピューティクス, インク. 5-ヒドロキシトリプトファン胃内滞留性剤形
US11779567B2 (en) 2021-10-14 2023-10-10 Evecxia Therapeutics, Inc. Method for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE575792C (de) * 1930-11-18 1933-05-03 Karl Glaessner Dr Verfahren zur Herstellung von UEberzuegen oder Huellen fuer Heilmittel
US3185626A (en) 1963-03-06 1965-05-25 Sterling Drug Inc Tablet coating method
FR1603314A (en) * 1965-02-23 1971-04-05 Pharmaceutical tablets - having a core and a matrix material
US3760804A (en) * 1971-01-13 1973-09-25 Alza Corp Improved osmotic dispenser employing magnesium sulphate and magnesium chloride
BE794951A (fr) * 1972-02-03 1973-05-29 Parke Davis & Co Conditionnement soluble dans l'eau
GB1594102A (en) * 1977-09-26 1981-07-30 Sankyo Co Ingestible coating compositions
US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4683256A (en) 1980-11-06 1987-07-28 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4449983A (en) 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4576604A (en) 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4828841A (en) 1984-07-24 1989-05-09 Colorcon, Inc. Maltodextrin coating
US4643894A (en) 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
US4802924A (en) 1986-06-19 1989-02-07 Colorcon, Inc. Coatings based on polydextrose for aqueous film coating of pharmaceutical food and confectionary products
US4816262A (en) * 1986-08-28 1989-03-28 Universite De Montreal Controlled release tablet
US4820524A (en) 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
CA1330886C (en) * 1988-01-22 1994-07-26 Bend Research Inc. Osmotic system for delivery of dilute solutions
US4906478A (en) 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
NZ233403A (en) 1989-04-28 1992-09-25 Mcneil Ppc Inc Simulated capsule-like medicament
US5146730A (en) 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
US5275822A (en) 1989-10-19 1994-01-04 Valentine Enterprises, Inc. Defoaming composition
FR2657257B1 (fr) * 1990-01-19 1994-09-02 Rhone Poulenc Sante Procede de preparation de medicaments sous forme de perles.
US5460824A (en) 1990-06-27 1995-10-24 Warner-Lambert Company Method for the preparation of an encapsulated medicament
US5464631A (en) 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
US5538125A (en) 1990-11-05 1996-07-23 Mcneil-Ppc, Inc. Indexing and feeding systems for apparatus for gelatin coating tablets
US5228916A (en) 1990-11-05 1993-07-20 Mcneil-Ppc, Inc. Apparatus for creating a gelatin coating
US5436026A (en) 1990-11-05 1995-07-25 Mcneil-Ppc, Inc. Discharge and transfer system for apparatus for gelatin coating tablets
US5503673A (en) 1990-11-05 1996-04-02 Mcneil-Ppc, Inc Apparatus for dip coating product
WO1993012765A1 (en) * 1991-12-27 1993-07-08 Merck & Co., Inc. A controlled release drug dispersion delivery device
JP3703481B2 (ja) 1992-01-17 2005-10-05 バーウィンド・ファーマスーティカル・サーヴィスィーズ・インコーポレーテッド セルロース重合体およびラクトースに基づくフィルム被覆および被覆組成物
US5427614A (en) 1992-02-14 1995-06-27 Warner-Lambert Company Starch based formulations
US5256440A (en) 1992-06-22 1993-10-26 Merck & Co., Inc. Process for producing a tablet core aperture
US5317849A (en) 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
JPH07507564A (ja) * 1992-09-30 1995-08-24 ファイザー・インク. コア及び厚さが一定でないコーティングを含有する物品
US5415868A (en) 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
HU225964B1 (en) * 1994-07-12 2008-01-28 Berwind Pharma Service Moisture barrier film coating composition, method, and coated form
DE4431653C2 (de) * 1994-09-06 2000-01-20 Lohmann Therapie Syst Lts Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
CN1132566C (zh) 1994-12-16 2003-12-31 沃尼尔·朗伯公司 在胶囊中填充囊芯的方法和由该方法制得的固体剂型
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
IT1289160B1 (it) * 1997-01-08 1998-09-29 Jagotec Ag Compressa farmaceutica completamente rivestita per il rilascio controllato di principi attivi che presentano problemi di
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
US6103260A (en) 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US6110499A (en) * 1997-07-24 2000-08-29 Alza Corporation Phenytoin therapy
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US6337091B1 (en) * 1997-10-27 2002-01-08 Temple University - Of The Commonwealth System Of Higher Education Matrix for controlled delivery of highly soluble pharmaceutical agents
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
HK1046638B (zh) * 1998-06-03 2006-02-24 阿尔扎有限公司 提供药物长效治疗的方法和装置
US6602521B1 (en) * 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
US6599532B2 (en) * 2000-01-13 2003-07-29 Osmotica Corp. Osmotic device containing alprazolam and an antipsychotic agent
GB0002305D0 (en) 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
GB0027471D0 (en) * 2000-11-08 2000-12-27 Smithkline Beecham Plc Processes
FR2816840B1 (fr) * 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
DE10109763A1 (de) * 2001-02-28 2002-09-05 Gruenenthal Gmbh Pharmazeutische Salze

Also Published As

Publication number Publication date
WO2004028511A1 (en) 2004-04-08
RU2005108609A (ru) 2006-03-10
WO2004028508A1 (en) 2004-04-08
WO2004028514A1 (en) 2004-04-08
RU2005108608A (ru) 2005-10-27
EP1542662A1 (de) 2005-06-22
EP1545472B1 (de) 2010-12-08
KR20050072093A (ko) 2005-07-08
CA2499882C (en) 2010-11-09
EP1551374B1 (de) 2009-10-07
WO2004028512A1 (en) 2004-04-08
CA2499977A1 (en) 2004-04-08
CA2499979A1 (en) 2004-04-08
CA2499882A1 (en) 2004-04-08
KR20050071517A (ko) 2005-07-07
CA2499955A1 (en) 2004-04-08
EP1542661B1 (de) 2013-12-18
WO2004028504A1 (en) 2004-04-08
EP1542661A1 (de) 2005-06-22
RU2005108577A (ru) 2006-06-10
NZ538842A (en) 2008-03-28
KR100995486B1 (ko) 2010-11-22
KR20050084605A (ko) 2005-08-26
WO2004028513A1 (en) 2004-04-08
WO2004028510A1 (en) 2004-04-08
EP1545472A1 (de) 2005-06-29
ES2355233T3 (es) 2011-03-24
EP1551374A1 (de) 2005-07-13
CA2499979C (en) 2012-09-11
RU2005108611A (ru) 2005-09-20
RU2005108576A (ru) 2005-09-20
EP2255795A1 (de) 2010-12-01
EP1545452A1 (de) 2005-06-29
WO2004028504A8 (en) 2005-10-20

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