ATE490764T1 - Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung - Google Patents

Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung

Info

Publication number
ATE490764T1
ATE490764T1 AT03798655T AT03798655T ATE490764T1 AT E490764 T1 ATE490764 T1 AT E490764T1 AT 03798655 T AT03798655 T AT 03798655T AT 03798655 T AT03798655 T AT 03798655T AT E490764 T1 ATE490764 T1 AT E490764T1
Authority
AT
Austria
Prior art keywords
core
opening
sustained release
release pharmaceutical
pharmaceutical forms
Prior art date
Application number
AT03798655T
Other languages
English (en)
Inventor
Harry Sowden
Gerard Mcnally
David Wynn
Oliver Anderson
Original Assignee
Mcneil Ppc Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2002/031024 external-priority patent/WO2003026625A1/en
Application filed by Mcneil Ppc Inc filed Critical Mcneil Ppc Inc
Application granted granted Critical
Publication of ATE490764T1 publication Critical patent/ATE490764T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806Coating materials
    • A61K9/2833Organic macromolecular compounds
    • A61K9/284Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0002Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2072Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2095Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/28Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2893Tablet coating processes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT03798655T 2002-09-28 2003-03-21 Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung ATE490764T1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PCT/US2002/031024 WO2003026625A1 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2002/031163 WO2003026627A1 (en) 2001-09-28 2002-09-28 Composite dosage forms
PCT/US2002/031062 WO2003026626A2 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2002/031129 WO2003026630A1 (en) 2001-09-28 2002-09-28 Dosage forms having an inner core and outer shell with different shapes
PCT/US2002/031117 WO2003026629A2 (en) 2001-09-28 2002-09-28 Modified release dosage forms
PCT/US2003/008894 WO2004028508A1 (en) 2002-09-28 2003-03-21 Modified release dosage forms with two cores and an opening

Publications (1)

Publication Number Publication Date
ATE490764T1 true ATE490764T1 (de) 2010-12-15

Family

ID=32046115

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03798655T ATE490764T1 (de) 2002-09-28 2003-03-21 Darreichungsformen zur verzögerten freisetzung mit zwei kernen und einer öffnung

Country Status (8)

Country Link
EP (6) EP2255795A1 (de)
KR (3) KR20050084605A (de)
AT (1) ATE490764T1 (de)
CA (4) CA2499955A1 (de)
ES (1) ES2355233T3 (de)
NZ (1) NZ538842A (de)
RU (5) RU2005108608A (de)
WO (7) WO2004028512A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040253312A1 (en) * 2001-09-28 2004-12-16 Sowden Harry S. Immediate release dosage form comprising shell having openings therein
AU2004231362B2 (en) 2003-04-24 2009-11-12 Jagotec Ag Delayed release tablet with defined core geometry
US7879354B2 (en) 2004-01-13 2011-02-01 Mcneil-Ppc, Inc. Rapidly disintegrating gelatinous coated tablets
PT2295049E (pt) * 2005-09-09 2015-03-02 Novartis Ag Tratamento de doenças auto-imunes
US20070231389A1 (en) * 2006-03-28 2007-10-04 Bunick Frank J Non-homogenous dosage form coatings
CA2612989A1 (en) * 2006-05-08 2007-11-08 Mcneil-Ppc, Inc. Osmotic dosage form
ES2400446T5 (es) 2006-08-03 2017-03-13 Horizon Pharma Ag Tratamiento con glucocorticoides de liberación retardada de una enfermedad reumática
US20080075766A1 (en) * 2006-09-25 2008-03-27 Shun-Por Li Multi-core dosage form having transparent outer coating
EP2299986A1 (de) * 2008-06-19 2011-03-30 University Of The Witwatersrand, Johannesburg Chronotherapeutische pharmazeutische dosierform
WO2012070028A1 (en) * 2010-11-26 2012-05-31 University Of The Witwatersrand, Johannesburg A pharmaceutical dosage form
EP2729180B1 (de) 2011-07-08 2019-01-23 The University of North Carolina At Chapel Hill Metall-bisphosphonat-nanopartikel zur krebstherapie sowie bildgebung und zur behandlung von knochenerkrankungen
WO2015069926A1 (en) 2013-11-06 2015-05-14 The University Of Chicago Nanoscale carriers for the delivery or co-delivery of chemotherapeutics, nucleic acids and photosensitizers
US11246877B2 (en) 2016-05-20 2022-02-15 The University Of Chicago Nanoparticles for chemotherapy, targeted therapy, photodynamic therapy, immunotherapy, and any combination thereof
EP3638367A4 (de) 2017-08-02 2021-07-21 The University of Chicago Nanoskalige metallorganische schichten und metallorganische nanoplatten für die röntgenstrahlinduzierte photodynamische therapie, strahlentherapie, dynamische strahlentherapie, chemotherapie, immuntherapie und eine beliebige kombination davon
US11419824B2 (en) 2017-12-29 2022-08-23 Laxxon Medical Ag Drug delivery system
MX2020013654A (es) * 2018-06-19 2021-03-25 Nat Univ Singapore Formulaciones de 5-hidroxitriptofano (5-htp) para mejor biodisponibilidad para diversas indicaciones.
CN111529548B (zh) * 2020-05-13 2022-07-26 上海美农生物科技股份有限公司 肠溶氧化锌颗粒
KR102651137B1 (ko) * 2021-01-08 2024-03-22 김주봉 성기능 개선을 위한 건강보조식품용 환의 제조방법
AU2022320730A1 (en) * 2021-07-30 2024-03-14 Evecxia Therapeutics, Inc. 5-hydroxytryptophan gastroretentive dosage forms
US11779567B2 (en) 2021-10-14 2023-10-10 Evecxia Therapeutics, Inc. Method for optimizing 5-hydroxytryptamine function in the brain for therapeutic purposes

Family Cites Families (58)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE575792C (de) * 1930-11-18 1933-05-03 Karl Glaessner Dr Verfahren zur Herstellung von UEberzuegen oder Huellen fuer Heilmittel
US3185626A (en) 1963-03-06 1965-05-25 Sterling Drug Inc Tablet coating method
FR1603314A (en) * 1965-02-23 1971-04-05 Pharmaceutical tablets - having a core and a matrix material
US3760804A (en) * 1971-01-13 1973-09-25 Alza Corp Improved osmotic dispenser employing magnesium sulphate and magnesium chloride
BE794951A (fr) * 1972-02-03 1973-05-29 Parke Davis & Co Conditionnement soluble dans l'eau
GB1594102A (en) * 1977-09-26 1981-07-30 Sankyo Co Ingestible coating compositions
US4543370A (en) 1979-11-29 1985-09-24 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4683256A (en) 1980-11-06 1987-07-28 Colorcon, Inc. Dry edible film coating composition, method and coating form
US4449983A (en) 1982-03-22 1984-05-22 Alza Corporation Simultaneous delivery of two drugs from unit delivery device
US4576604A (en) 1983-03-04 1986-03-18 Alza Corporation Osmotic system with instant drug availability
US4643894A (en) 1984-07-24 1987-02-17 Colorcon, Inc. Maltodextrin coating
US4828841A (en) 1984-07-24 1989-05-09 Colorcon, Inc. Maltodextrin coating
US4802924A (en) 1986-06-19 1989-02-07 Colorcon, Inc. Coatings based on polydextrose for aqueous film coating of pharmaceutical food and confectionary products
US4816262A (en) * 1986-08-28 1989-03-28 Universite De Montreal Controlled release tablet
US4820524A (en) * 1987-02-20 1989-04-11 Mcneilab, Inc. Gelatin coated caplets and process for making same
CA1330886C (en) * 1988-01-22 1994-07-26 Bend Research Inc. Osmotic system for delivery of dilute solutions
US4906478A (en) 1988-12-12 1990-03-06 Valentine Enterprises, Inc. Simethicone/calcium silicate composition
US5032384A (en) * 1989-01-27 1991-07-16 Block Drug Company, Inc. Compositions and method for the treatment of disease
NZ233403A (en) 1989-04-28 1992-09-25 Mcneil Ppc Inc Simulated capsule-like medicament
US5146730A (en) 1989-09-20 1992-09-15 Banner Gelatin Products Corp. Film-enrobed unitary-core medicament and the like
US5275822A (en) 1989-10-19 1994-01-04 Valentine Enterprises, Inc. Defoaming composition
FR2657257B1 (fr) * 1990-01-19 1994-09-02 Rhone Poulenc Sante Procede de preparation de medicaments sous forme de perles.
US5464631A (en) 1990-06-27 1995-11-07 Warner-Lambert Company Encapsulated dosage forms
US5460824A (en) 1990-06-27 1995-10-24 Warner-Lambert Company Method for the preparation of an encapsulated medicament
US5228916A (en) 1990-11-05 1993-07-20 Mcneil-Ppc, Inc. Apparatus for creating a gelatin coating
US5538125A (en) 1990-11-05 1996-07-23 Mcneil-Ppc, Inc. Indexing and feeding systems for apparatus for gelatin coating tablets
US5503673A (en) 1990-11-05 1996-04-02 Mcneil-Ppc, Inc Apparatus for dip coating product
US5436026A (en) 1990-11-05 1995-07-25 Mcneil-Ppc, Inc. Discharge and transfer system for apparatus for gelatin coating tablets
HU219594B (hu) * 1991-12-27 2001-05-28 Merck And Co. Inc. Szabályozott diszperziós hatóanyag-leadó eszköz és eljárás előállítására
AU674840B2 (en) 1992-01-17 1997-01-16 Bpsi Holdings, Inc. Film coatings and film coating compositions based on cellulosic polymers and lactose
US5427614A (en) 1992-02-14 1995-06-27 Warner-Lambert Company Starch based formulations
US5256440A (en) 1992-06-22 1993-10-26 Merck & Co., Inc. Process for producing a tablet core aperture
US5317849A (en) 1992-08-07 1994-06-07 Sauter Manufacturing Corporation Encapsulation equipment and method
US5609884A (en) * 1992-08-31 1997-03-11 G. D. Searle & Co. Controlled release naproxen sodium plus naproxen combination tablet
IT1255522B (it) * 1992-09-24 1995-11-09 Ubaldo Conte Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita'
WO1994007470A1 (en) * 1992-09-30 1994-04-14 Pfizer Inc. Article containing a core and a coating having a non constant thickness
US5415868A (en) 1993-06-09 1995-05-16 L. Perrigo Company Caplets with gelatin cover and process for making same
JP3672314B2 (ja) * 1994-07-12 2005-07-20 バーウィンド・ファーマスーティカル・サーヴィスィーズ・インコーポレーテッド 防湿性フィルム被覆材組成物、方法および被覆成形物
DE4431653C2 (de) * 1994-09-06 2000-01-20 Lohmann Therapie Syst Lts Manteltablette zur kontrollierten Freisetzung von Wirkstoffen, ein Verfahren zu ihrer Herstellung und ihre Verwendung
US6245350B1 (en) 1994-12-16 2001-06-12 Warner-Lambert Company Process for encapsulation of caplets in a capsule and solid dosage forms obtainable by such process
DK0797424T3 (da) 1994-12-16 2000-10-23 Warner Lambert Co Fremgangsmåde til indkapsling af caplets i en kapsel og faste doseringsformer, der kan fremstilles ved denne fremgamgsmåde
IT1289160B1 (it) * 1997-01-08 1998-09-29 Jagotec Ag Compressa farmaceutica completamente rivestita per il rilascio controllato di principi attivi che presentano problemi di
US6210710B1 (en) * 1997-04-28 2001-04-03 Hercules Incorporated Sustained release polymer blend for pharmaceutical applications
US6103260A (en) 1997-07-17 2000-08-15 Mcneil-Ppc, Inc. Simethicone/anhydrous calcium phosphate compositions
US6110499A (en) * 1997-07-24 2000-08-29 Alza Corporation Phenytoin therapy
AR017512A1 (es) * 1997-08-22 2001-09-12 Smithkline Beecham Corp Tabletas de metilcelulosa rapidamente desintegrables para administracion por via oral y procedimiento para prepararlas
US6337091B1 (en) * 1997-10-27 2002-01-08 Temple University - Of The Commonwealth System Of Higher Education Matrix for controlled delivery of highly soluble pharmaceutical agents
US6365185B1 (en) * 1998-03-26 2002-04-02 University Of Cincinnati Self-destructing, controlled release peroral drug delivery system
DE69920689T2 (de) * 1998-06-03 2005-02-24 Alza Corp., Mountain View Vorrichtungen zum Aufrechterhalten eines gewünschten therapeutischen Medikamenteneffekts über einen verlängerten Therapiezeitraum
US6602521B1 (en) * 1998-09-29 2003-08-05 Impax Pharmaceuticals, Inc. Multiplex drug delivery system suitable for oral administration
US6274162B1 (en) 2000-01-14 2001-08-14 Bpsi Holdings, Inc. Elegant film coating system
US6599532B2 (en) * 2000-01-13 2003-07-29 Osmotica Corp. Osmotic device containing alprazolam and an antipsychotic agent
GB0002305D0 (en) 2000-02-01 2000-03-22 Phoqus Limited Power material for electrostatic application
US6375982B1 (en) * 2000-07-05 2002-04-23 Capricorn Pharma, Inc. Rapid-melt semi-solid compositions, methods of making same and method of using same
US20030086972A1 (en) * 2000-08-09 2003-05-08 Appel Leah E. Hydrogel-driven drug dosage form
GB0027471D0 (en) * 2000-11-08 2000-12-27 Smithkline Beecham Plc Processes
FR2816840B1 (fr) * 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
DE10109763A1 (de) * 2001-02-28 2002-09-05 Gruenenthal Gmbh Pharmazeutische Salze

Also Published As

Publication number Publication date
EP1542662A1 (de) 2005-06-22
EP1542661A1 (de) 2005-06-22
ES2355233T3 (es) 2011-03-24
WO2004028512A1 (en) 2004-04-08
CA2499977A1 (en) 2004-04-08
EP1545472A1 (de) 2005-06-29
KR100995486B1 (ko) 2010-11-22
CA2499955A1 (en) 2004-04-08
RU2005108611A (ru) 2005-09-20
EP1545452A1 (de) 2005-06-29
WO2004028508A1 (en) 2004-04-08
WO2004028510A1 (en) 2004-04-08
KR20050084605A (ko) 2005-08-26
WO2004028504A1 (en) 2004-04-08
EP1545472B1 (de) 2010-12-08
CA2499882A1 (en) 2004-04-08
WO2004028504A8 (en) 2005-10-20
WO2004028514A1 (en) 2004-04-08
KR20050072093A (ko) 2005-07-08
RU2005108576A (ru) 2005-09-20
CA2499882C (en) 2010-11-09
NZ538842A (en) 2008-03-28
WO2004028511A1 (en) 2004-04-08
RU2005108609A (ru) 2006-03-10
EP1551374B1 (de) 2009-10-07
EP2255795A1 (de) 2010-12-01
KR20050071517A (ko) 2005-07-07
EP1551374A1 (de) 2005-07-13
RU2005108608A (ru) 2005-10-27
CA2499979A1 (en) 2004-04-08
RU2005108577A (ru) 2006-06-10
CA2499979C (en) 2012-09-11
WO2004028513A1 (en) 2004-04-08
EP1542661B1 (de) 2013-12-18

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