ATE488271T1 - Führungsschablone zur brachytherapie - Google Patents
Führungsschablone zur brachytherapieInfo
- Publication number
- ATE488271T1 ATE488271T1 AT03076748T AT03076748T ATE488271T1 AT E488271 T1 ATE488271 T1 AT E488271T1 AT 03076748 T AT03076748 T AT 03076748T AT 03076748 T AT03076748 T AT 03076748T AT E488271 T1 ATE488271 T1 AT E488271T1
- Authority
- AT
- Austria
- Prior art keywords
- real time
- processing means
- emitting source
- energy emitting
- dimensional image
- Prior art date
Links
- 238000002725 brachytherapy Methods 0.000 title 1
- 238000003384 imaging method Methods 0.000 abstract 2
- 210000003484 anatomy Anatomy 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 238000003709 image segmentation Methods 0.000 abstract 1
- 238000005457 optimization Methods 0.000 abstract 1
- 210000000056 organ Anatomy 0.000 abstract 1
- 230000005855 radiation Effects 0.000 abstract 1
- 238000001959 radiotherapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1031—Treatment planning systems using a specific method of dose optimization
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1039—Treatment planning systems using functional images, e.g. PET or MRI
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
- G16H20/40—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to mechanical, radiation or invasive therapies, e.g. surgery, laser therapy, dialysis or acupuncture
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H30/00—ICT specially adapted for the handling or processing of medical images
- G16H30/40—ICT specially adapted for the handling or processing of medical images for processing medical images, e.g. editing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
- A61N5/1007—Arrangements or means for the introduction of sources into the body
- A61N2005/1012—Templates or grids for guiding the introduction of sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/103—Treatment planning systems
- A61N5/1031—Treatment planning systems using a specific method of dose optimization
- A61N2005/1032—Genetic optimization methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N2005/1074—Details of the control system, e.g. user interfaces
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Health & Medical Sciences (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- Pathology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Primary Health Care (AREA)
- Medical Informatics (AREA)
- Epidemiology (AREA)
- Surgery (AREA)
- Urology & Nephrology (AREA)
- Radiation-Therapy Devices (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Thermotherapy And Cooling Therapy Devices (AREA)
- Finger-Pressure Massage (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20020077436 EP1374949B1 (de) | 2002-06-17 | 2002-06-17 | System zur Echtzeitplanung von Strahlentherapie |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE488271T1 true ATE488271T1 (de) | 2010-12-15 |
Family
ID=29716888
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02077436T ATE312648T1 (de) | 2002-06-17 | 2002-06-17 | System zur echtzeitplanung von strahlentherapie |
| AT03076748T ATE488271T1 (de) | 2002-06-17 | 2003-06-05 | Führungsschablone zur brachytherapie |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02077436T ATE312648T1 (de) | 2002-06-17 | 2002-06-17 | System zur echtzeitplanung von strahlentherapie |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US7899517B2 (de) |
| EP (1) | EP1374949B1 (de) |
| JP (1) | JP4439843B2 (de) |
| AT (2) | ATE312648T1 (de) |
| AU (1) | AU2003204404B2 (de) |
| CA (1) | CA2432493C (de) |
| DE (2) | DE60208009T2 (de) |
| ES (2) | ES2254599T3 (de) |
| PT (1) | PT1374951E (de) |
Families Citing this family (53)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2254599T3 (es) | 2002-06-17 | 2006-06-16 | Nucletron B.V. | Sistema de planificacion de tratamiento por radiacion en tiempo real. |
| US7742902B1 (en) * | 2003-10-22 | 2010-06-22 | Oracle America, Inc. | Using interval techniques of direct comparison and differential formulation to solve a multi-objective optimization problem |
| DE102004040629B4 (de) * | 2004-08-19 | 2011-05-19 | MedCom Gesellschaft für medizinische Bildverarbeitung mbH | Einstellen einer Relativposition einer Bestrahlungseinrichtung und eines Patienten |
| US20060067467A1 (en) * | 2004-09-28 | 2006-03-30 | Minnesota Medical Physics Llc | Apparatus and method for conformal radiation brachytherapy for breast and other tumors |
| DE602004022964D1 (de) | 2004-12-23 | 2009-10-15 | Nucletron Bv | Verfahren und Vorrichtung zur Berechnung der Strahlendosisverteilung für ein Strahlentherapiesystem |
| US8775207B2 (en) * | 2005-02-02 | 2014-07-08 | Siemens Medical Solutions Usa, Inc. | Integrated treatment planning and scheduling system |
| US8409071B2 (en) * | 2005-05-17 | 2013-04-02 | Wisconsin Alumni Research Foundation | Method and apparatus for treatment planning using implanted radioactive sources |
| EP1994958B1 (de) * | 2005-07-18 | 2012-12-12 | Nucletron Operations B.V. | Vorrichtung und Verfahren zur Durchführung einer Strahlenbehandlung eines vorbestimmten anatomischen Teils eines Tierkörpers |
| EP1745820B1 (de) | 2005-07-18 | 2010-02-17 | Nucletron B.V. | System zur Durchführung einer Strahlenbehandlung auf einen vorgewählten anatomischen Teil eines Körpers |
| EP1921982A2 (de) * | 2005-08-25 | 2008-05-21 | Koninklijke Philips Electronics N.V. | Planungsverfahren auf der basis von 4d-bildern und vorrichtung zur gezielten therapie |
| WO2007133932A2 (en) * | 2006-05-11 | 2007-11-22 | Koninklijke Philips Electronics, N.V. | Deformable registration of images for image guided radiation therapy |
| US7771339B2 (en) * | 2006-05-31 | 2010-08-10 | Ab Mimator | Method and system for radiotherapy treatment |
| US7728868B2 (en) | 2006-08-02 | 2010-06-01 | Inneroptic Technology, Inc. | System and method of providing real-time dynamic imagery of a medical procedure site using multiple modalities |
| EP2355708B1 (de) * | 2008-10-20 | 2015-01-21 | Vanderbilt University | System und verfahren zur beschleunigung von strahlenbehandlungssimulierungen |
| US11464578B2 (en) | 2009-02-17 | 2022-10-11 | Inneroptic Technology, Inc. | Systems, methods, apparatuses, and computer-readable media for image management in image-guided medical procedures |
| US8690776B2 (en) | 2009-02-17 | 2014-04-08 | Inneroptic Technology, Inc. | Systems, methods, apparatuses, and computer-readable media for image guided surgery |
| NL1037031C2 (en) * | 2009-06-11 | 2010-12-16 | Nucletron Bv | Radiation therapy delivery system and radiation therapy treatment planning system. |
| NL1037032C2 (en) * | 2009-06-11 | 2010-12-16 | Nucletron Bv | A system and method for generating a radiation treatment plan for use in effecting radiation therapy in a human or animal body. |
| US8315357B2 (en) * | 2009-10-08 | 2012-11-20 | The Board Of Trustees Of The Leland Stanford Junior University | Radiation therapy inverse treatment planning using a regularization of sparse segments |
| US8819591B2 (en) * | 2009-10-30 | 2014-08-26 | Accuray Incorporated | Treatment planning in a virtual environment |
| JP5916145B2 (ja) | 2010-03-31 | 2016-05-11 | メディ−フィジックス・インコーポレイテッド | ブラキセラピーテンプレートアダプター |
| TW201221117A (en) * | 2010-11-29 | 2012-06-01 | Iner Aec Executive Yuan | Enhancing segmentation for molecular image quantification system and the method thereof |
| CN102136041B (zh) * | 2011-04-18 | 2017-04-26 | 深圳市海博科技有限公司 | 治疗计划系统 |
| US10245447B2 (en) * | 2011-10-18 | 2019-04-02 | Koninklijke Philips N.V. | Magnetic resonance imaging guided brachytherapy with displaying the catheter placement position |
| WO2013116240A1 (en) * | 2012-01-30 | 2013-08-08 | Inneroptic Technology, Inc. | Multiple medical device guidance |
| CN104470584B (zh) | 2012-07-17 | 2018-10-16 | 皇家飞利浦有限公司 | 用于确定引入元件的姿势和形状的确定装置 |
| JP6317749B2 (ja) | 2012-10-29 | 2018-04-25 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 自動的な最適imrt/vmat処置計画の生成 |
| BR112015013047A2 (pt) * | 2012-12-06 | 2017-07-11 | Koninklijke Philips Nv | aparelho de calibração para calibrar um sistema para introduzir um elemento de influência em um objeto, aparelho de determinação de plano de influência, método de calibração para calibrar um sistema para introduzir um elemento de influência em um objeto, método de determinação de plano de influência e programa de computador de calibração para calibrar um sistema para introduzir um elemento de influência em um objeto |
| US20140206926A1 (en) * | 2013-01-18 | 2014-07-24 | Robert van der LAARSE | Methods for optimizing and evaluating dose distributions in brachytherpay |
| US10092251B2 (en) | 2013-03-15 | 2018-10-09 | Varian Medical Systems, Inc. | Prospective evaluation of tumor visibility for IGRT using templates generated from planning CT and contours |
| US20150202464A1 (en) * | 2014-01-23 | 2015-07-23 | Mitsubis | Multi-Criteria Optimization in Particle Beam Dose Optimization |
| US10786310B2 (en) * | 2014-03-24 | 2020-09-29 | Koninklijke Philips N.V. | Quality assurance and data coordination for electromagnetic tracking systems |
| US9844684B2 (en) * | 2014-04-30 | 2017-12-19 | Stc.Unm | Optimization methods for radiation therapy planning |
| US9901406B2 (en) | 2014-10-02 | 2018-02-27 | Inneroptic Technology, Inc. | Affected region display associated with a medical device |
| US10188467B2 (en) | 2014-12-12 | 2019-01-29 | Inneroptic Technology, Inc. | Surgical guidance intersection display |
| EP3076317B1 (de) * | 2015-04-02 | 2018-08-15 | RaySearch Laboratories AB | System und verfahren zur bereitstellung eines behandlungsplanes einer strahlentherapie und ein strahlentherapiegerät |
| US9949700B2 (en) | 2015-07-22 | 2018-04-24 | Inneroptic Technology, Inc. | Medical device approaches |
| WO2017037060A1 (en) * | 2015-09-01 | 2017-03-09 | Koninklijke Philips N.V. | Device and method for assisting in a brachytherapy procedure |
| US11565126B2 (en) * | 2015-09-11 | 2023-01-31 | Varian Medical Systems International Ag | Knowledge based multi-criteria optimization for radiotherapy treatment planning |
| US9675319B1 (en) | 2016-02-17 | 2017-06-13 | Inneroptic Technology, Inc. | Loupe display |
| EP3506835B1 (de) * | 2016-09-01 | 2023-08-02 | Oregon Health & Science University | Vorrichtung zur durch anatomisches erfassungssystem geführten endorektalen prostatabiopsie |
| US10278778B2 (en) | 2016-10-27 | 2019-05-07 | Inneroptic Technology, Inc. | Medical device navigation using a virtual 3D space |
| JP2020501698A (ja) | 2016-12-16 | 2020-01-23 | コーニンクレッカ フィリップス エヌ ヴェKoninklijke Philips N.V. | 焦点放射線治療のための位置決め支援デバイス |
| FI131860B1 (en) * | 2017-03-17 | 2026-01-13 | Planmeca Oy | Self-calibrating medical imaging device |
| US11259879B2 (en) | 2017-08-01 | 2022-03-01 | Inneroptic Technology, Inc. | Selective transparency to assist medical device navigation |
| US11484365B2 (en) | 2018-01-23 | 2022-11-01 | Inneroptic Technology, Inc. | Medical image guidance |
| WO2020113381A1 (zh) * | 2018-12-03 | 2020-06-11 | 深圳先进技术研究院 | 一种超声成像方法及装置 |
| US11744643B2 (en) | 2019-02-04 | 2023-09-05 | Covidien Lp | Systems and methods facilitating pre-operative prediction of post-operative tissue function |
| EP3892224A1 (de) | 2020-04-10 | 2021-10-13 | Koninklijke Philips N.V. | Rasterschablonenpositionierung in der interventionellen medizin |
| CN111986777B (zh) * | 2020-07-31 | 2024-08-02 | 上海联影医疗科技股份有限公司 | 放射治疗计划优化系统、装置和存储介质 |
| CN112516471B (zh) * | 2020-12-01 | 2021-08-27 | 北京航空航天大学 | 基于扩展收缩理论的放疗计划仿真设计方法及系统 |
| EP4015038A1 (de) * | 2020-12-18 | 2022-06-22 | Koninklijke Philips N.V. | Strahlentherapieplanung |
| GB2642070A (en) * | 2024-06-21 | 2025-12-31 | Nucletron Operations Bv | Medical applicator |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5372138A (en) * | 1988-03-21 | 1994-12-13 | Boston Scientific Corporation | Acousting imaging catheters and the like |
| US5391139A (en) | 1992-09-03 | 1995-02-21 | William Beaumont Hospital | Real time radiation treatment planning system |
| DE69326455T2 (de) * | 1993-07-01 | 2000-01-20 | Schneider (Europe) Gmbh, Buelach | Arzneigeräte für die Behandlung von Blutgefässen mittels ionisierungsbestrahlung |
| JP2852178B2 (ja) * | 1993-12-28 | 1999-01-27 | 日本電気株式会社 | フィルムキャリアテープ |
| US5626829A (en) * | 1994-11-16 | 1997-05-06 | Pgk, Enterprises, Inc. | Method and apparatus for interstitial radiation of the prostate gland |
| US6256529B1 (en) * | 1995-07-26 | 2001-07-03 | Burdette Medical Systems, Inc. | Virtual reality 3D visualization for surgical procedures |
| US6234951B1 (en) * | 1996-02-29 | 2001-05-22 | Scimed Life Systems, Inc. | Intravascular radiation delivery system |
| US6095975A (en) * | 1997-05-27 | 2000-08-01 | Silvern; David A. | Apparatus and method for determining optimal locations to place radioactive seeds at a cancerous site |
| US6019718A (en) * | 1997-05-30 | 2000-02-01 | Scimed Life Systems, Inc. | Apparatus for intravascular radioactive treatment |
| US5931786A (en) * | 1997-06-13 | 1999-08-03 | Barzell Whitmore Maroon Bells, Inc. | Ultrasound probe support and stepping device |
| US6083167A (en) * | 1998-02-10 | 2000-07-04 | Emory University | Systems and methods for providing radiation therapy and catheter guides |
| US6360116B1 (en) * | 1998-02-27 | 2002-03-19 | Varian Medical Systems, Inc. | Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-operative planning and post-operative evaluations |
| US6327490B1 (en) * | 1998-02-27 | 2001-12-04 | Varian Medical Systems, Inc. | Brachytherapy system for prostate cancer treatment with computer implemented systems and processes to facilitate pre-implantation planning and post-implantation evaluations with storage of multiple plan variations for a single patient |
| US6387034B1 (en) * | 1998-08-17 | 2002-05-14 | Georia Tech Research Corporation | Brachytherapy treatment planning method and apparatus |
| US6200255B1 (en) * | 1998-10-30 | 2001-03-13 | University Of Rochester | Prostate implant planning engine for radiotherapy |
| US6610013B1 (en) * | 1999-10-01 | 2003-08-26 | Life Imaging Systems, Inc. | 3D ultrasound-guided intraoperative prostate brachytherapy |
| US6438401B1 (en) * | 2000-04-28 | 2002-08-20 | Alpha Intervention Technology, Inc. | Indentification and quantification of needle displacement departures from treatment plan |
| US6561980B1 (en) * | 2000-05-23 | 2003-05-13 | Alpha Intervention Technology, Inc | Automatic segmentation of prostate, rectum and urethra in ultrasound imaging |
| US6500109B2 (en) * | 2000-07-21 | 2002-12-31 | Tayman Medical, Inc. | Prostate treatment template |
| US7022062B1 (en) * | 2000-08-30 | 2006-04-04 | Murphy Brian B | Radioactive seed implantation system and method |
| EP1314452B1 (de) * | 2001-11-23 | 2005-08-10 | Nucletron B.V. | Automatische bildgesteuerte Einrichtung zur Einführung einer Kanüle in einen menschlichen oder tierischen Körper zur Strahlentherapie im diesem Körper |
| ES2254599T3 (es) * | 2002-06-17 | 2006-06-16 | Nucletron B.V. | Sistema de planificacion de tratamiento por radiacion en tiempo real. |
| US7041048B2 (en) * | 2002-10-16 | 2006-05-09 | Sourcetech Medical, Llc | Apparatus and method for dose administration in brachytherapy |
-
2002
- 2002-06-17 ES ES02077436T patent/ES2254599T3/es not_active Expired - Lifetime
- 2002-06-17 DE DE2002608009 patent/DE60208009T2/de not_active Expired - Lifetime
- 2002-06-17 EP EP20020077436 patent/EP1374949B1/de not_active Expired - Lifetime
- 2002-06-17 AT AT02077436T patent/ATE312648T1/de not_active IP Right Cessation
-
2003
- 2003-05-28 AU AU2003204404A patent/AU2003204404B2/en not_active Ceased
- 2003-05-30 US US10/448,311 patent/US7899517B2/en not_active Expired - Lifetime
- 2003-06-05 DE DE60334956T patent/DE60334956D1/de not_active Expired - Lifetime
- 2003-06-05 PT PT03076748T patent/PT1374951E/pt unknown
- 2003-06-05 AT AT03076748T patent/ATE488271T1/de not_active IP Right Cessation
- 2003-06-05 ES ES03076748T patent/ES2355700T3/es not_active Expired - Lifetime
- 2003-06-16 CA CA2432493A patent/CA2432493C/en not_active Expired - Lifetime
- 2003-06-17 JP JP2003172377A patent/JP4439843B2/ja not_active Expired - Fee Related
-
2011
- 2011-01-25 US US13/013,051 patent/US8301228B2/en not_active Expired - Fee Related
-
2012
- 2012-09-24 US US13/625,662 patent/US8744553B2/en not_active Expired - Lifetime
-
2014
- 2014-04-23 US US14/260,009 patent/US9381377B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP4439843B2 (ja) | 2010-03-24 |
| US20130102831A1 (en) | 2013-04-25 |
| US20150105606A1 (en) | 2015-04-16 |
| CA2432493C (en) | 2016-08-30 |
| ES2355700T3 (es) | 2011-03-30 |
| AU2003204404A1 (en) | 2004-01-15 |
| DE60208009D1 (de) | 2006-01-19 |
| US7899517B2 (en) | 2011-03-01 |
| US8744553B2 (en) | 2014-06-03 |
| DE60334956D1 (de) | 2010-12-30 |
| PT1374951E (pt) | 2011-02-07 |
| EP1374949B1 (de) | 2005-12-14 |
| US9381377B2 (en) | 2016-07-05 |
| JP2004041725A (ja) | 2004-02-12 |
| DE60208009T2 (de) | 2006-08-24 |
| US20030233123A1 (en) | 2003-12-18 |
| US8301228B2 (en) | 2012-10-30 |
| EP1374949A1 (de) | 2004-01-02 |
| ES2254599T3 (es) | 2006-06-16 |
| CA2432493A1 (en) | 2003-12-17 |
| AU2003204404B2 (en) | 2007-05-10 |
| US20110288361A1 (en) | 2011-11-24 |
| ATE312648T1 (de) | 2005-12-15 |
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