ATE484752T1 - Verfahren zur unterscheidung zwischen ischämischem und hämorrhagischem schlaganfall - Google Patents
Verfahren zur unterscheidung zwischen ischämischem und hämorrhagischem schlaganfallInfo
- Publication number
- ATE484752T1 ATE484752T1 AT04768075T AT04768075T ATE484752T1 AT E484752 T1 ATE484752 T1 AT E484752T1 AT 04768075 T AT04768075 T AT 04768075T AT 04768075 T AT04768075 T AT 04768075T AT E484752 T1 ATE484752 T1 AT E484752T1
- Authority
- AT
- Austria
- Prior art keywords
- ischemic
- differentiation
- hemorrhagic stroke
- apo
- subject
- Prior art date
Links
- 208000016988 Hemorrhagic Stroke Diseases 0.000 title 1
- 208000032382 Ischaemic stroke Diseases 0.000 title 1
- 230000004069 differentiation Effects 0.000 title 1
- 208000020658 intracerebral hemorrhage Diseases 0.000 title 1
- 230000000302 ischemic effect Effects 0.000 title 1
- 102000004411 Antithrombin III Human genes 0.000 abstract 1
- 108090000935 Antithrombin III Proteins 0.000 abstract 1
- 102000005666 Apolipoprotein A-I Human genes 0.000 abstract 1
- 108010059886 Apolipoprotein A-I Proteins 0.000 abstract 1
- 102000011772 Apolipoprotein C-I Human genes 0.000 abstract 1
- 108010076807 Apolipoprotein C-I Proteins 0.000 abstract 1
- 102000030169 Apolipoprotein C-III Human genes 0.000 abstract 1
- 108010056301 Apolipoprotein C-III Proteins 0.000 abstract 1
- 102000054727 Serum Amyloid A Human genes 0.000 abstract 1
- 108700028909 Serum Amyloid A Proteins 0.000 abstract 1
- 208000006011 Stroke Diseases 0.000 abstract 1
- 229960005348 antithrombin iii Drugs 0.000 abstract 1
- 210000001124 body fluid Anatomy 0.000 abstract 1
- 239000010839 body fluid Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
- G01N2333/4701—Details
- G01N2333/4709—Amyloid plaque core protein
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/775—Apolipopeptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
- G01N2333/8121—Serpins
- G01N2333/8128—Antithrombin III
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB0319167A GB2404981A (en) | 2003-08-15 | 2003-08-15 | Diagnostic method for stroke |
| PCT/GB2004/003512 WO2005017523A2 (en) | 2003-08-15 | 2004-08-16 | Method for discriminating between ischemic and haemorrhagic stroke |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE484752T1 true ATE484752T1 (de) | 2010-10-15 |
Family
ID=28052545
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04768075T ATE484752T1 (de) | 2003-08-15 | 2004-08-16 | Verfahren zur unterscheidung zwischen ischämischem und hämorrhagischem schlaganfall |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7767401B2 (de) |
| EP (1) | EP1671130B1 (de) |
| JP (2) | JP4949026B2 (de) |
| AT (1) | ATE484752T1 (de) |
| AU (1) | AU2004264560B2 (de) |
| CA (1) | CA2535890C (de) |
| DE (1) | DE602004029594D1 (de) |
| ES (1) | ES2350164T3 (de) |
| GB (1) | GB2404981A (de) |
| WO (1) | WO2005017523A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007002069A2 (en) | 2005-06-21 | 2007-01-04 | Anthony Goncalves | Serum biomarkers for breast cancer |
| EP1969363B1 (de) * | 2005-12-22 | 2016-11-30 | Abbott Molecular Inc. | Verfahren und markerkombinationen zum screening auf eine veranlagung zu lungenkrebs |
| US9347945B2 (en) | 2005-12-22 | 2016-05-24 | Abbott Molecular Inc. | Methods and marker combinations for screening for predisposition to lung cancer |
| AP2008004634A0 (en) * | 2006-03-23 | 2008-10-31 | Emelta De Guzman Breyer | Apolipoprotein fingerprinting technique |
| WO2008008846A2 (en) * | 2006-07-11 | 2008-01-17 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Differential expression of molecules associated with intra-cerebral hemorrhage |
| CA2735525A1 (en) * | 2008-08-04 | 2010-02-11 | The Board Of Regents Of The University Of Texas System | Multiplexed diagnostic test for preterm labor |
| JP5747370B2 (ja) * | 2009-03-31 | 2015-07-15 | 国立大学法人浜松医科大学 | 高病原性口腔細菌の高感度検出法 |
| US20100331673A1 (en) * | 2009-06-26 | 2010-12-30 | Michael Maschke | System and method for reducing patient risk of allergic reaction to contrast agents or medical material |
| US20100332254A1 (en) * | 2009-06-26 | 2010-12-30 | Michael Maschke | In-vitro device support for x-ray based kidney function test |
| KR20120101064A (ko) * | 2009-11-13 | 2012-09-12 | 비쥐 메디신, 인코포레이티드 | 심근 경색의 위험 인자 및 예측 |
| US20120064558A1 (en) * | 2010-09-13 | 2012-03-15 | Lopez Mary Frances | Assays for Differentiating between Ischemic and Hemorrhagic Stroke in a Human Patient |
| WO2013088429A1 (en) * | 2011-12-13 | 2013-06-20 | Kieran Gerard Walshe | A homogeneous competitive lateral flow assay |
| SG11201506886TA (en) | 2013-03-14 | 2015-09-29 | Bayer Healthcare Llc | Monoclonal antibodies against antithrombin beta complexed with heparin |
| AU2017292184A1 (en) | 2016-07-08 | 2019-02-07 | Staten Biotechnology B.V. | Anti-Apoc3 antibodies and methods of use thereof |
| JP2020517242A (ja) | 2017-04-21 | 2020-06-18 | スターテン・バイオテクノロジー・ベー・フェー | 抗ＡｐｏＣ３抗体およびその使用方法 |
| KR20200074975A (ko) | 2017-10-31 | 2020-06-25 | 스태튼 바이오테크놀로지 비.브이. | 항-ApoC3 항체 및 이의 사용 방법 |
| US10538583B2 (en) | 2017-10-31 | 2020-01-21 | Staten Biotechnology B.V. | Anti-APOC3 antibodies and compositions thereof |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4801531A (en) | 1985-04-17 | 1989-01-31 | Biotechnology Research Partners, Ltd. | Apo AI/CIII genomic polymorphisms predictive of atherosclerosis |
| US5320945A (en) * | 1989-07-14 | 1994-06-14 | Boehringer Mannheim Gmbh | Method and reagent for the determination of antithrombin III |
| US6017693A (en) * | 1994-03-14 | 2000-01-25 | University Of Washington | Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry |
| US6107045A (en) * | 1994-06-30 | 2000-08-22 | Oklahoma Medical Research Foundation | Antibodies to lipoproteins and apolipoproteins and methods of use thereof |
| JPH08178923A (ja) * | 1994-12-21 | 1996-07-12 | Cosmo Sogo Kenkyusho:Kk | リポタンパク質又はアポリポタンパク質の免疫学的測定方法 |
| US6429017B1 (en) * | 1999-02-04 | 2002-08-06 | Biomerieux | Method for predicting the presence of haemostatic dysfunction in a patient sample |
| US5985582A (en) * | 1997-12-09 | 1999-11-16 | Sigma-Aldrich Co. | Thrombin-based assay for antithrombin III |
| CA2263063C (en) * | 1999-02-26 | 2004-08-10 | Skye Pharmatech Incorporated | Method for diagnosing and distinguishing stroke and diagnostic devices for use therein |
| WO2001064008A2 (en) * | 2000-03-03 | 2001-09-07 | Smithkline Beecham Biologicals S.A. | Vaccine for the treatment of artherosclerosis |
| AU2001249275B2 (en) * | 2000-03-20 | 2005-12-08 | Eastern Virginia Medical School | Prostate cancer markers |
| JP3561218B2 (ja) * | 2000-08-10 | 2004-09-02 | 株式会社いかがく | 動脈硬化性病変の診断用キット |
| JP2005522669A (ja) * | 2001-08-20 | 2005-07-28 | バイオサイト インコーポレイテッド | 卒中および脳損傷の診断マーカーおよびその使用方法 |
| GB0203768D0 (en) * | 2002-02-18 | 2002-04-03 | Univ Geneve | Diagnostic method for stroke |
-
2003
- 2003-08-15 GB GB0319167A patent/GB2404981A/en not_active Withdrawn
-
2004
- 2004-08-16 JP JP2006523059A patent/JP4949026B2/ja not_active Expired - Lifetime
- 2004-08-16 US US10/568,093 patent/US7767401B2/en active Active
- 2004-08-16 ES ES04768075T patent/ES2350164T3/es not_active Expired - Lifetime
- 2004-08-16 EP EP04768075A patent/EP1671130B1/de not_active Expired - Lifetime
- 2004-08-16 CA CA2535890A patent/CA2535890C/en not_active Expired - Lifetime
- 2004-08-16 WO PCT/GB2004/003512 patent/WO2005017523A2/en not_active Ceased
- 2004-08-16 AU AU2004264560A patent/AU2004264560B2/en not_active Expired
- 2004-08-16 AT AT04768075T patent/ATE484752T1/de not_active IP Right Cessation
- 2004-08-16 DE DE602004029594T patent/DE602004029594D1/de not_active Expired - Lifetime
-
2011
- 2011-07-01 JP JP2011147291A patent/JP2011221037A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP1671130B1 (de) | 2010-10-13 |
| GB0319167D0 (en) | 2003-09-17 |
| JP4949026B2 (ja) | 2012-06-06 |
| GB2404981A (en) | 2005-02-16 |
| CA2535890C (en) | 2015-05-05 |
| US7767401B2 (en) | 2010-08-03 |
| WO2005017523A2 (en) | 2005-02-24 |
| DE602004029594D1 (de) | 2010-11-25 |
| CA2535890A1 (en) | 2005-02-24 |
| JP2011221037A (ja) | 2011-11-04 |
| US20070166758A1 (en) | 2007-07-19 |
| JP2007502401A (ja) | 2007-02-08 |
| AU2004264560A1 (en) | 2005-02-24 |
| ES2350164T3 (es) | 2011-01-19 |
| AU2004264560B2 (en) | 2009-07-30 |
| WO2005017523A3 (en) | 2005-05-12 |
| EP1671130A2 (de) | 2006-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |