ATE48426T1 - Hydrochlorid von 2-aminoalkyl-9hydroxyellipticinium-chloridderivaten und diese enthaltende pharmazeutische zubereitungen. - Google Patents
Hydrochlorid von 2-aminoalkyl-9hydroxyellipticinium-chloridderivaten und diese enthaltende pharmazeutische zubereitungen.Info
- Publication number
- ATE48426T1 ATE48426T1 AT86870099T AT86870099T ATE48426T1 AT E48426 T1 ATE48426 T1 AT E48426T1 AT 86870099 T AT86870099 T AT 86870099T AT 86870099 T AT86870099 T AT 86870099T AT E48426 T1 ATE48426 T1 AT E48426T1
- Authority
- AT
- Austria
- Prior art keywords
- group selected
- alk
- groups
- propylene
- lower alkyl
- Prior art date
Links
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 title abstract 6
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- -1 1,2-ethylene, 1,2-propylene, 1,3-propylene Chemical group 0.000 abstract 6
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- QZTWUDDGLIDXSE-UHFFFAOYSA-N 9-hydroxyellipticine Chemical compound N1=CC=C2C(C)=C(NC=3C4=CC(O)=CC=3)C4=C(C)C2=C1 QZTWUDDGLIDXSE-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000001805 chlorine compounds Chemical class 0.000 abstract 2
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000004108 n-butyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 2
- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 2
- 125000001436 propyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000003960 organic solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8510257A FR2584409B1 (fr) | 1985-07-04 | 1985-07-04 | Chlorhydrates de chlorures de derives d'aminoalkyl-2 hydroxy-9 ellipticinium et compositions pharmaceutiques en contenant |
| EP86870099A EP0209511B1 (de) | 1985-07-04 | 1986-07-02 | Hydrochlorid von 2-Aminoalkyl-9-hydroxyellipticinium-Chloridderivaten und diese enthaltende pharmazeutische Zubereitungen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE48426T1 true ATE48426T1 (de) | 1989-12-15 |
Family
ID=9320978
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT86870099T ATE48426T1 (de) | 1985-07-04 | 1986-07-02 | Hydrochlorid von 2-aminoalkyl-9hydroxyellipticinium-chloridderivaten und diese enthaltende pharmazeutische zubereitungen. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4897398A (de) |
| EP (1) | EP0209511B1 (de) |
| JP (1) | JPH0742287B2 (de) |
| AT (1) | ATE48426T1 (de) |
| DE (1) | DE3667285D1 (de) |
| FR (1) | FR2584409B1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5424315A (en) * | 1993-08-02 | 1995-06-13 | Sri International | Benzothiophen analogs as antiviral agents |
| US6231894B1 (en) | 1999-10-21 | 2001-05-15 | Duke University | Treatments based on discovery that nitric oxide synthase is a paraquat diaphorase |
| EP2026809A2 (de) * | 2006-05-22 | 2009-02-25 | BioAlliance Pharma | Umwandlung von malignen phenotypen durch 9-hydroxy ellipticine derivates |
| FR2942476B1 (fr) | 2009-02-20 | 2013-03-15 | Commissariat Energie Atomique | Composes de type pyridocarbazole et leurs applications |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4310667A (en) * | 1976-04-22 | 1982-01-12 | Agence Nationale De Valorisation De La Recherche (Anvar) | 2-N Quaternary ammonium salt derivatives of 9-hydroxy ellipticine |
| FR2485015A1 (fr) * | 1980-06-18 | 1981-12-24 | Anvar | Derives de l'olivacine et leur application therapeutique |
| US4816462A (en) * | 1982-05-18 | 1989-03-28 | Nowicky Wassili | Method for diagnosing and for the therapeutic treatment of tumors and/or infectious diseases of different types with alkaloid-compounds |
-
1985
- 1985-07-04 FR FR8510257A patent/FR2584409B1/fr not_active Expired
-
1986
- 1986-06-24 US US06/877,801 patent/US4897398A/en not_active Expired - Fee Related
- 1986-07-02 EP EP86870099A patent/EP0209511B1/de not_active Expired
- 1986-07-02 AT AT86870099T patent/ATE48426T1/de not_active IP Right Cessation
- 1986-07-02 DE DE8686870099T patent/DE3667285D1/de not_active Expired - Lifetime
- 1986-07-04 JP JP61158624A patent/JPH0742287B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0742287B2 (ja) | 1995-05-10 |
| JPS6210084A (ja) | 1987-01-19 |
| EP0209511B1 (de) | 1989-12-06 |
| US4897398A (en) | 1990-01-30 |
| EP0209511A1 (de) | 1987-01-21 |
| FR2584409B1 (fr) | 1987-11-20 |
| DE3667285D1 (de) | 1990-01-11 |
| FR2584409A1 (fr) | 1987-01-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |