ATE480230T1 - Vorrichtung und verfahren mit einem mikroverkapselten protonenspender zur freisetzung von stickoxid aus einem polymer - Google Patents

Vorrichtung und verfahren mit einem mikroverkapselten protonenspender zur freisetzung von stickoxid aus einem polymer

Info

Publication number
ATE480230T1
ATE480230T1 AT06708239T AT06708239T ATE480230T1 AT E480230 T1 ATE480230 T1 AT E480230T1 AT 06708239 T AT06708239 T AT 06708239T AT 06708239 T AT06708239 T AT 06708239T AT E480230 T1 ATE480230 T1 AT E480230T1
Authority
AT
Austria
Prior art keywords
micro
polymer
nitrogen oxide
proton donor
releasing nitrogen
Prior art date
Application number
AT06708239T
Other languages
English (en)
Inventor
Tor Peters
Original Assignee
Nolabs Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nolabs Ab filed Critical Nolabs Ab
Application granted granted Critical
Publication of ATE480230T1 publication Critical patent/ATE480230T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007Drug-containing films, membranes or sheets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5052Proteins, e.g. albumin
    • A61K9/5057Gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Treatment Of Fiber Materials (AREA)
  • Polyesters Or Polycarbonates (AREA)
AT06708239T 2005-08-23 2006-02-13 Vorrichtung und verfahren mit einem mikroverkapselten protonenspender zur freisetzung von stickoxid aus einem polymer ATE480230T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05018269A EP1757278A1 (de) 2005-08-23 2005-08-23 Vorrichtung, System und Methode enthaltend eine verkapselte Flüssigkeit zur Stickstoffmonoxyd-Freisetzung von einem Polymer
US71100605P 2005-08-24 2005-08-24
PCT/EP2006/050902 WO2007023005A1 (en) 2005-08-23 2006-02-13 Device, system, and method comprising microencapsulated proton donor for release of nitric oxide from a polymer

Publications (1)

Publication Number Publication Date
ATE480230T1 true ATE480230T1 (de) 2010-09-15

Family

ID=35466085

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06708239T ATE480230T1 (de) 2005-08-23 2006-02-13 Vorrichtung und verfahren mit einem mikroverkapselten protonenspender zur freisetzung von stickoxid aus einem polymer

Country Status (13)

Country Link
US (1) US20090148482A1 (de)
EP (2) EP1757278A1 (de)
JP (1) JP2009514792A (de)
KR (1) KR20080037677A (de)
CN (1) CN101242815B (de)
AT (1) ATE480230T1 (de)
BR (1) BRPI0617097A2 (de)
CA (1) CA2617507A1 (de)
DE (1) DE602006016818D1 (de)
ES (1) ES2352075T3 (de)
MX (1) MX2008002550A (de)
RU (1) RU2008104412A (de)
WO (1) WO2007023005A1 (de)

Families Citing this family (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006100154A1 (en) 2005-03-24 2006-09-28 Nolabs Ab Cosmetic treatment with nitric oxide, device for performing said treatment and manufacturing method therefor
CA2606565C (en) 2005-05-27 2016-05-10 The University Of North Carolina At Chapel Hill Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications
RU2009139781A (ru) * 2007-03-27 2011-05-10 Нолабс Аб (Se) Устройство для доставки оксида азота для местного воздействия на кожу
GB0715556D0 (en) * 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
WO2009131931A1 (en) * 2008-04-21 2009-10-29 3M Innovative Properties Company Nitric oxide-releasing compositions, devices and methods
WO2010048724A1 (en) * 2008-10-30 2010-05-06 Chris Miller Nitric oxide-releasing dressings
GB0821345D0 (en) 2008-11-21 2008-12-31 P Q Silicas Uk Ltd Composition and dressing with nitric oxide
ES2958410T3 (es) 2009-08-21 2024-02-08 Novan Inc Geles tópicos
BR112012003804B1 (pt) * 2009-08-21 2019-02-19 Novan, Inc. Curativo para ferimentos, método para formar um curativo para ferimentos, e, kit de curativo para ferimento
EP2555762B1 (de) 2010-04-06 2018-01-31 Syracuse University System und verfahren zur freisetzung von stickoxid mithilfe nanoskaliger medien
KR101255337B1 (ko) 2010-10-04 2013-04-16 한국과학기술연구원 온도 감응성 합성 고분자를 이용한 일산화질소 전달체
US8591876B2 (en) 2010-12-15 2013-11-26 Novan, Inc. Methods of decreasing sebum production in the skin
US11951139B2 (en) 2015-11-30 2024-04-09 Seed Health, Inc. Method and system for reducing the likelihood of osteoporosis
US11951140B2 (en) 2011-02-04 2024-04-09 Seed Health, Inc. Modulation of an individual's gut microbiome to address osteoporosis and bone disease
US11844720B2 (en) 2011-02-04 2023-12-19 Seed Health, Inc. Method and system to reduce the likelihood of dental caries and halitosis
US20170100328A1 (en) * 2011-02-04 2017-04-13 Joseph E. Kovarik Bioadhesive Strip and Method of Using Same
WO2012118829A2 (en) 2011-02-28 2012-09-07 Novan, Inc. Tertiary s-nitrosothiol-modified nitricoxide-releasing xerogels and methods of using the same
JP2014508166A (ja) * 2011-03-17 2014-04-03 トランスダーマル バイオテクノロジ インコーポレーテッド 局所的一酸化窒素システム及びその使用方法
EP2691087A2 (de) 2011-03-31 2014-02-05 László Gábor Szabó Pharmazeutische zusammensetzung mit no, verfahren zu ihrer herstellung und verwendung
WO2012153331A2 (en) 2011-05-09 2012-11-15 Topical Therapeutic Agent (Tta) Ltd. Nitric oxide-sequestering topical formulations
EP2729131B1 (de) 2011-07-05 2020-04-15 Novan, Inc. Topische zusammensetzungen
WO2013006613A1 (en) 2011-07-05 2013-01-10 Novan, Inc. Methods of manufacturing topical compositions and apparatus for same
US11077194B2 (en) 2012-03-14 2021-08-03 Novan, Inc. Nitric oxide releasing pharmaceutical compositions
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US9855211B2 (en) 2013-02-28 2018-01-02 Novan, Inc. Topical compositions and methods of using the same
BR112016002387B1 (pt) 2013-08-08 2019-05-21 Novan, Inc. Composições farmacêuticas tópicas, e método para seu armazenamento
US10206947B2 (en) 2013-08-08 2019-02-19 Novan, Inc. Topical compositions and methods of using the same
US11980643B2 (en) 2013-12-20 2024-05-14 Seed Health, Inc. Method and system to modify an individual's gut-brain axis to provide neurocognitive protection
US11969445B2 (en) 2013-12-20 2024-04-30 Seed Health, Inc. Probiotic composition and method for controlling excess weight, obesity, NAFLD and NASH
US11826388B2 (en) 2013-12-20 2023-11-28 Seed Health, Inc. Topical application of Lactobacillus crispatus to ameliorate barrier damage and inflammation
US11833177B2 (en) 2013-12-20 2023-12-05 Seed Health, Inc. Probiotic to enhance an individual's skin microbiome
US11839632B2 (en) 2013-12-20 2023-12-12 Seed Health, Inc. Topical application of CRISPR-modified bacteria to treat acne vulgaris
KR101555523B1 (ko) * 2014-02-28 2015-09-25 부산대학교 산학협력단 산화질소 방출성 상처치료 필름 및 이의 제조방법
WO2015130096A1 (ko) * 2014-02-28 2015-09-03 부산대학교 산학협력단 산화질소 방출성 상처치료 필름 및 이의 제조방법
BR112017000456B1 (pt) 2014-07-11 2022-12-13 Novan, Inc Uso de um ingrediente farmacêutico ativo de liberação de óxido nítrico e composição tópica para tratamento e/ou prevenção de uma infecção viral
US10322082B2 (en) 2014-07-11 2019-06-18 Novan, Inc. Topical antiviral compositions and methods of using the same
WO2016010988A1 (en) 2014-07-14 2016-01-21 Novan, Inc. Nitric oxide releasing nail coating compositions, nitric oxide releasing nail coatings, and methods of using the same
JP6488130B2 (ja) * 2015-01-08 2019-03-20 花王株式会社 積層シート及びその使用方法
WO2017019614A1 (en) 2015-07-28 2017-02-02 Novan, Inc. Combinations and methods for the treatment and/or prevention of fungal infections
KR101577951B1 (ko) 2015-09-23 2015-12-16 기초과학연구원 다공성 코어-쉘 나노입자와 인산칼슘을 이용한 선택적 일산화질소 방출 방법
KR102319497B1 (ko) 2016-03-02 2021-11-01 노반, 인크. 염증 치료용 조성물 및 염증 치료 방법
CN116585257A (zh) 2016-04-13 2023-08-15 诺万公司 用于治疗感染的组合物、系统、试剂盒和方法
CN105832656B (zh) * 2016-05-25 2018-10-09 暨南大学 一种载一氧化氮的羧化壳聚糖-聚乙烯亚胺水凝胶及其制备方法和应用
JP2021515807A (ja) 2018-03-01 2021-06-24 ノーバン,インク. 一酸化窒素放出性坐剤及びその使用の方法
CN112618158A (zh) * 2019-10-09 2021-04-09 咏达生医材料股份有限公司 一种供给一氧化氮的多层装置

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649075A (en) * 1984-08-09 1987-03-10 Leonora Jost Transdermal and transmucosal vortexed foam devices and the method of making
DK0807396T3 (da) 1991-12-20 2004-07-12 Fisher & Paykel Appliances Ltd Opvaskemaskine
US5910316A (en) * 1992-08-24 1999-06-08 The United States Of America, As Represented By The Department Of Health And Human Services Use of nitric oxide-releasing agents to treat impotency
US5519020A (en) * 1994-10-28 1996-05-21 The University Of Akron Polymeric wound healing accelerators
US5770645A (en) 1996-08-02 1998-06-23 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US5888528A (en) * 1997-05-19 1999-03-30 Bernard Technologies, Inc. Sustained release biocidal powders
US5994444A (en) * 1997-10-16 1999-11-30 Medtronic, Inc. Polymeric material that releases nitric oxide
WO2000022207A2 (en) 1998-10-01 2000-04-20 The University Of Akron Process and apparatus for the production of nanofibers
ATE339982T1 (de) * 1999-07-12 2006-10-15 Capnia Inc Anordnung zur behandlung von kopfschmerzen, rhinitis und anderen leiden
US6737447B1 (en) 1999-10-08 2004-05-18 The University Of Akron Nitric oxide-modified linear poly(ethylenimine) fibers and uses thereof
NZ500167A (en) 1999-10-08 2002-07-26 Fisher & Paykel Appliances Ltd Dishwasher adapted to be mounted in a cavity
US6706274B2 (en) * 2001-01-18 2004-03-16 Scimed Life Systems, Inc. Differential delivery of nitric oxide
US6520425B1 (en) 2001-08-21 2003-02-18 The University Of Akron Process and apparatus for the production of nanofibers
US6695992B2 (en) 2002-01-22 2004-02-24 The University Of Akron Process and apparatus for the production of nanofibers
WO2006058318A2 (en) * 2004-11-29 2006-06-01 The University Of Akron Topical nitric oxide donor devices
EP1681068A1 (de) 2004-12-16 2006-07-19 NOLabs AB Stickstoffmonoxyd eluierende Filtriervorrichtung
EP1700611A1 (de) 2005-02-11 2006-09-13 NOLabs AB Vorrichtung zur Behandlung von Krankheiten der Mundhöhle und deren Herstellungsprozess
EP1690532A1 (de) 2005-02-11 2006-08-16 NOLabs AB Vorrichtung zur Behandlung vom Magen und ihr Verfahren zur Herstellung
EP1704877A1 (de) 2005-03-24 2006-09-27 NOLabs AB Artikel zur Wundbehandlung mit einem Stickstoffoxide abgebenden Polymerüberzug
EP1704876A1 (de) 2005-03-24 2006-09-27 NOLabs AB Kosmetische Behandlung, Vorrichtung zur Durchführung dieser Behandlung und deren Herstellungsmethode
EP1704879A1 (de) 2005-03-24 2006-09-27 NOLabs AB Medizinische Vorrichtung für intravasculäre, interstitiel oder intra-Organ-Applikation mit einem Stickstoffoxide abgebenden Polymerüberzug
EP1728438A1 (de) 2005-06-01 2006-12-06 NOLabs AB Futtermittel
EP1731176A1 (de) 2005-06-01 2006-12-13 NOLabs AB Vorrichtung zur Vorbehandlung beinhaltend Stickstoffmonoxid

Also Published As

Publication number Publication date
EP1757278A1 (de) 2007-02-28
CN101242815B (zh) 2012-11-28
EP1917005B1 (de) 2010-09-08
RU2008104412A (ru) 2009-09-27
US20090148482A1 (en) 2009-06-11
KR20080037677A (ko) 2008-04-30
JP2009514792A (ja) 2009-04-09
DE602006016818D1 (de) 2010-10-21
WO2007023005A1 (en) 2007-03-01
EP1917005A1 (de) 2008-05-07
CN101242815A (zh) 2008-08-13
MX2008002550A (es) 2008-03-14
EP1917005B8 (de) 2011-05-25
ES2352075T3 (es) 2011-02-15
CA2617507A1 (en) 2007-03-01
BRPI0617097A2 (pt) 2011-07-12

Similar Documents

Publication Publication Date Title
ATE480230T1 (de) Vorrichtung und verfahren mit einem mikroverkapselten protonenspender zur freisetzung von stickoxid aus einem polymer
DE50112115D1 (de) Verfahren und Vorrichtung zur Zustandserfassung von technischen Systemen wie Energiespeicher
DE502006008737D1 (de) Vorrichtung und verfahren zur automatisierten isolierung und aufreinigung von nukleinsäuren aus beliebigen komplexen ausgangsmaterialien
WO2015002677A8 (en) Alkaline activation for immobilization of dna taggants
DE112007001829A5 (de) Bauteil mit Haltefunktion, Aufhaltesystem und Verfahren zu deren Betrieb
WO2008097559A3 (en) Manipulation of fluids and reactions in microfluidic systems
DE602005000943D1 (de) Verfahren und Vorrichtung zur sicheren Übertragung von Inhalten mit Urheberschutz
DE602005026500D1 (de) Vorrichtung zur Handhaben von mikrofluidischen Vorrichtungen mit einer Klemmeinrichtung
DE602007008781D1 (de) Elektronische Vorrichtung und diese verwendendes Steuerungsverfahren für eine externe Vorrichtung
ATE308700T1 (de) Verbindungsvorrichtung und verfahren zur kupplung von biologischen geräten zu einer quelle
CA2553892A1 (en) Contained micro-particles for use in well bore operations
DE602006017081D1 (de) Verfahren zum zusammenhalten von verpackungen und zum halten von komponenten daran
ATE357283T1 (de) Mehrstufige vorrichtung und verfahren zur trennung von fluiden
WO2011053845A3 (en) Microvessels, microparticles, and methods of manufacturing and using the same
DK1750700T3 (da) Veterinærmedicinsk væskepræparat, fremgangsmåde til fremstilling af dette samt anvendelse deraf
DE60308050D1 (de) Verfahren und vorrichtung zur vorbehandlung von proben durch zentrifugieren
DE502005010645D1 (de) Vorrichtung und Verfahren zur Erkennung von Behältern und Gebinden
DE112007000683A5 (de) Vorrichtung zur Durchführung und Untersuchung biologischer Proben mit temperaturgesteuerten biologischen Reaktionen
EP2060916A4 (de) Fluoreszenz-halbleitermikropartikelanordnung, fluoreszenzmarkierungsmittelanordnung für eine biologische substanz und biologisches bildgebungsverfahren sowie analyseverfahren für biologische substanzen mit verwendung der anordnungen
ATE430812T1 (de) Materialien und verfahren zum einfangen von krankheitserregern und zur abtrennung von aurintricarbonsäure aus einer probe
WO2005044367A3 (en) Method and apparatus for cell permeabilization
DE602004022776D1 (de) Vorrichtung mit verlängerter freisetzung und verfahren zur okularen verabreichung von adrenergen wirkstoffen
DE602004016422D1 (de) Verfahren und Vorrichtung zur Prüfung von Halbleiterelementen
DE502006003941D1 (de) Verfahren und vorrichtung zum vollautomatischen abkuppeln und ankuppeln von sattelaufliegern
DE10314203A8 (de) Verfahren zur Trennung/Aufarbeitung von(meth)acrylsäurehaltigen Gemischen durch Einsatz von ionischen Flüssigkeiten und hyperverzweigten Polymeren

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties