ATE475639T1 - Biphenylderivate als selektive agonisten von gamma-rar-rezeptoren - Google Patents
Biphenylderivate als selektive agonisten von gamma-rar-rezeptorenInfo
- Publication number
- ATE475639T1 ATE475639T1 AT06819799T AT06819799T ATE475639T1 AT E475639 T1 ATE475639 T1 AT E475639T1 AT 06819799 T AT06819799 T AT 06819799T AT 06819799 T AT06819799 T AT 06819799T AT E475639 T1 ATE475639 T1 AT E475639T1
- Authority
- AT
- Austria
- Prior art keywords
- gamma
- selective agonists
- treating
- biphenyl derivatives
- rar receptors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- C07C65/17—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups containing rings other than six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Cosmetics (AREA)
- Lasers (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0512762A FR2894960B1 (fr) | 2005-12-15 | 2005-12-15 | Derives biphenyliques agonistes selectifs du recepteurs rar-gamma |
| PCT/EP2006/068975 WO2007068579A1 (fr) | 2005-12-15 | 2006-11-28 | Derives biphenyliques agonistes selectifs du recepteur rar-gamma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE475639T1 true ATE475639T1 (de) | 2010-08-15 |
Family
ID=36956106
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06819799T ATE475639T1 (de) | 2005-12-15 | 2006-11-28 | Biphenylderivate als selektive agonisten von gamma-rar-rezeptoren |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8106235B2 (de) |
| EP (1) | EP1963249B1 (de) |
| AT (1) | ATE475639T1 (de) |
| BR (1) | BRPI0620667A2 (de) |
| CA (1) | CA2632899C (de) |
| CY (1) | CY1110795T1 (de) |
| DE (1) | DE602006015850D1 (de) |
| DK (1) | DK1963249T3 (de) |
| ES (1) | ES2349478T3 (de) |
| FR (1) | FR2894960B1 (de) |
| PL (1) | PL1963249T3 (de) |
| PT (1) | PT1963249E (de) |
| SI (1) | SI1963249T1 (de) |
| WO (1) | WO2007068579A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103200937B (zh) | 2010-09-01 | 2020-07-03 | 托马斯杰弗逊大学 | 用于肌肉修复和再生的组合物和方法 |
| JP2019509262A (ja) | 2016-02-03 | 2019-04-04 | ガルデルマ・リサーチ・アンド・デヴェロップメント | 新規二芳香族プロピニル化合物、それらを含む薬学的および化粧用組成物ならびにそれらの使用 |
| BR112019026945A2 (pt) | 2017-07-06 | 2020-06-30 | Jiangsu Hengrui Medicine Co., Ltd. | derivado de indol-formamida, método de preparação para ele e seu uso em medicina |
| WO2019052440A1 (zh) | 2017-09-12 | 2019-03-21 | 江苏恒瑞医药股份有限公司 | 氘原子取代的吲哚甲酰胺类衍生物、其制备方法及其在医药上的应用 |
| US11135236B2 (en) | 2018-04-10 | 2021-10-05 | Northwestern University | Retinoic acid receptor gamma agonists to attenuate anthracycline-induced cardiotoxicity |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2767525B1 (fr) * | 1997-08-21 | 1999-11-12 | Cird Galderma | Derives biphenyliques substitues par un radical aromatique ou heteroaromatique et compositions pharmaceutiques et cosmetiques les contenant |
| ES2317076T3 (es) * | 2003-12-08 | 2009-04-16 | GALDERMA RESEARCH & DEVELOPMENT | Derivados bifenilicos utiles como ligandos que activan receptores rar, procedimiento para prepararlos y su utilizacion en medicina humana y en cosmeticos. |
-
2005
- 2005-12-15 FR FR0512762A patent/FR2894960B1/fr not_active Expired - Fee Related
-
2006
- 2006-11-28 PT PT06819799T patent/PT1963249E/pt unknown
- 2006-11-28 PL PL06819799T patent/PL1963249T3/pl unknown
- 2006-11-28 DE DE602006015850T patent/DE602006015850D1/de active Active
- 2006-11-28 AT AT06819799T patent/ATE475639T1/de active
- 2006-11-28 SI SI200630737T patent/SI1963249T1/sl unknown
- 2006-11-28 ES ES06819799T patent/ES2349478T3/es active Active
- 2006-11-28 BR BRPI0620667-0A patent/BRPI0620667A2/pt not_active IP Right Cessation
- 2006-11-28 DK DK06819799.5T patent/DK1963249T3/da active
- 2006-11-28 EP EP06819799A patent/EP1963249B1/de not_active Not-in-force
- 2006-11-28 CA CA2632899A patent/CA2632899C/fr not_active Expired - Fee Related
- 2006-11-28 WO PCT/EP2006/068975 patent/WO2007068579A1/fr active Application Filing
-
2008
- 2008-06-16 US US12/213,178 patent/US8106235B2/en not_active Expired - Fee Related
-
2010
- 2010-09-23 CY CY20101100857T patent/CY1110795T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US8106235B2 (en) | 2012-01-31 |
| DK1963249T3 (da) | 2010-11-01 |
| PT1963249E (pt) | 2010-09-17 |
| WO2007068579A1 (fr) | 2007-06-21 |
| PL1963249T3 (pl) | 2011-02-28 |
| SI1963249T1 (sl) | 2010-10-29 |
| EP1963249A1 (de) | 2008-09-03 |
| EP1963249B1 (de) | 2010-07-28 |
| FR2894960A1 (fr) | 2007-06-22 |
| ES2349478T3 (es) | 2011-01-03 |
| FR2894960B1 (fr) | 2008-02-29 |
| CA2632899A1 (fr) | 2007-06-21 |
| BRPI0620667A2 (pt) | 2011-11-22 |
| CY1110795T1 (el) | 2015-06-10 |
| US20090036536A1 (en) | 2009-02-05 |
| DE602006015850D1 (de) | 2010-09-09 |
| CA2632899C (fr) | 2013-11-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
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