ATE473275T1 - Menschliche aminoacyl-trna synthetase polypeptide zur regulation der angiogenese - Google Patents
Menschliche aminoacyl-trna synthetase polypeptide zur regulation der angiogeneseInfo
- Publication number
- ATE473275T1 ATE473275T1 AT01918876T AT01918876T ATE473275T1 AT E473275 T1 ATE473275 T1 AT E473275T1 AT 01918876 T AT01918876 T AT 01918876T AT 01918876 T AT01918876 T AT 01918876T AT E473275 T1 ATE473275 T1 AT E473275T1
- Authority
- AT
- Austria
- Prior art keywords
- trna synthetase
- angiogenesis
- regulation
- synthetase polypeptides
- human aminoacyl
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000052866 Amino Acyl-tRNA Synthetases Human genes 0.000 title abstract 2
- 108700028939 Amino Acyl-tRNA Synthetases Proteins 0.000 title abstract 2
- 230000006884 regulation of angiogenesis Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 2
- 101000640990 Arabidopsis thaliana Tryptophan-tRNA ligase, chloroplastic/mitochondrial Proteins 0.000 abstract 1
- 102000002501 Tryptophan-tRNA Ligase Human genes 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 102000039446 nucleic acids Human genes 0.000 abstract 1
- 108020004707 nucleic acids Proteins 0.000 abstract 1
- 150000007523 nucleic acids Chemical class 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Toxicology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Microbiology (AREA)
- Cardiology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Physical Education & Sports Medicine (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19347100P | 2000-03-31 | 2000-03-31 | |
| PCT/US2001/008975 WO2001075078A1 (en) | 2000-03-31 | 2001-03-21 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPEPTIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE473275T1 true ATE473275T1 (de) | 2010-07-15 |
Family
ID=22713774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01918876T ATE473275T1 (de) | 2000-03-31 | 2001-03-21 | Menschliche aminoacyl-trna synthetase polypeptide zur regulation der angiogenese |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US7067126B2 (de) |
| EP (3) | EP1272506B1 (de) |
| JP (2) | JP4868681B2 (de) |
| AT (1) | ATE473275T1 (de) |
| AU (6) | AU2001250904B2 (de) |
| CA (2) | CA2404488C (de) |
| DE (1) | DE60142508D1 (de) |
| IL (5) | IL151943A0 (de) |
| NZ (2) | NZ522182A (de) |
| WO (2) | WO2001075078A1 (de) |
Families Citing this family (62)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE473275T1 (de) * | 2000-03-31 | 2010-07-15 | Scripps Research Inst | Menschliche aminoacyl-trna synthetase polypeptide zur regulation der angiogenese |
| US7273844B2 (en) * | 2000-03-31 | 2007-09-25 | The Scripps Research Institute | Tryptophanyl-tRNA synthetase-derived polypeptides useful for the regulation of angiogenesis |
| US7144984B2 (en) * | 2000-03-31 | 2006-12-05 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
| RU2297425C2 (ru) * | 2001-02-23 | 2007-04-20 | Дзе Скриппс Рисерч Инститьют | Полипептиды, происходящие из триптофанил-трнк-синтетазы, и их применение для регуляции развития кровеносных сосудов |
| US6903189B2 (en) * | 2001-03-21 | 2005-06-07 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
| EP1547609A1 (de) * | 2002-09-04 | 2005-06-29 | Proteinexpress Co., Ltd. | Embryo-implantationsinhibitor |
| AU2005249586B2 (en) * | 2004-06-04 | 2010-12-23 | The Scripps Research Institute | Compositions and methods for treatment of neovascular diseases |
| US8282921B2 (en) | 2004-08-02 | 2012-10-09 | Paul Glidden | tRNA synthetase fragments |
| US20060079673A1 (en) * | 2004-08-02 | 2006-04-13 | Paul Glidden | Polynucleotides encoding tRNA synthetase fragments and uses thereof |
| CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
| WO2006055871A2 (en) * | 2004-11-19 | 2006-05-26 | Biogen Idec Ma Inc. | Treatment for multiple sclerosis |
| KR101244202B1 (ko) * | 2005-02-24 | 2013-03-18 | 더 스크립스 리서치 인스티튜트 | 허혈성 망막 조직의 혈관재형성 및 이의 스크리닝 방법 |
| EP1977004B1 (de) * | 2005-12-02 | 2014-10-29 | The Scripps Research Institute | Angiogene tyrosyl-trna-synthetase-zusammensetzungen und verfahren |
| US20110104139A1 (en) * | 2008-03-11 | 2011-05-05 | The University Of North Carolina At Chapel Hill | ANGIOSTATIC COMPOSITIONS COMPRISING TRUNCATED TYROSYL-tRNA SYNTHETASE POLYPEPTIDES AND METHODS OF USING SAME |
| ES2622444T3 (es) * | 2008-06-11 | 2017-07-06 | Atyr Pharma, Inc. | Actividad trombopoyética de polipéptidos tirosil-ARNt sintetasa |
| JP5756751B2 (ja) | 2008-06-26 | 2015-07-29 | エータイアー ファーマ， インコーポレイテッド | 非正準的な生物学的活性を有するグリシル−ｔＲＮＡ合成酵素を含む組成物および方法 |
| EP2403864B1 (de) | 2009-02-27 | 2015-08-12 | Atyr Pharma, Inc. | Polypeptidstrukturmotive im zusammenhang mit zellsignalisierungsaktivität |
| US9846533B2 (en) * | 2009-03-16 | 2017-12-19 | Apple Inc. | Methods and graphical user interfaces for editing on a multifunction device with a touch screen display |
| DK3255146T3 (da) | 2009-03-16 | 2019-08-19 | Pangu Biopharma Ltd | Præparater og fremgangsmåder omfattende histidyl-tRNA-synthetasesplejsningsvarianter med ikke-kanoniske biologiske aktiviteter |
| CN102449143B (zh) * | 2009-03-31 | 2017-11-14 | Atyr医药公司 | 包含具有非常规生物活性的天冬氨酰‑tRNA合成酶的组合物和方法 |
| MX2011010971A (es) * | 2009-04-17 | 2012-01-19 | Biogen Idec Inc | Composiciones y metodos para tratar leucemia mielogena aguda. |
| US8828395B2 (en) | 2009-12-11 | 2014-09-09 | Atyr Pharma, Inc. | Antibodies that bind tyrosyl-tRNA synthetases |
| WO2011072266A2 (en) * | 2009-12-11 | 2011-06-16 | Atyr Pharma, Inc. | Aminoacyl trna synthetases for modulating hematopoiesis |
| DK2509625T3 (en) | 2009-12-11 | 2015-04-27 | Atyr Pharma Inc | Histidyl tRNA synthetases to reduce inflammation |
| WO2011097031A2 (en) * | 2010-02-04 | 2011-08-11 | The Scripps Research Institute | Monomeric forms of human aminoacyl-trna synthetases having non-canonical biological activities |
| EP3466977B1 (de) | 2010-04-16 | 2022-01-05 | Biogen MA Inc. | Anti-vla-4-antikörper |
| AU2011248625B2 (en) | 2010-04-26 | 2017-01-05 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-tRNA synthetase |
| CN103096911B (zh) | 2010-04-27 | 2018-05-29 | Atyr 医药公司 | 与异亮氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| EP2563382B1 (de) | 2010-04-27 | 2017-06-07 | aTyr Pharma, Inc. | Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von threonyl-trna-synthetasen |
| CN103097524B (zh) * | 2010-04-28 | 2016-08-03 | Atyr医药公司 | 与丙氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| CN103118693B (zh) | 2010-04-29 | 2017-05-03 | Atyr 医药公司 | 与缬氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| CA2797374C (en) | 2010-04-29 | 2021-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases |
| US9068177B2 (en) | 2010-04-29 | 2015-06-30 | Atyr Pharma, Inc | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-tRNA synthetases |
| WO2011140135A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
| ES2623805T3 (es) | 2010-05-03 | 2017-07-12 | Atyr Pharma, Inc. | Descubrimiento innovador de composiciones terapéuticas, de diagnóstico y de anticuerpos relacionadas con fragmentos de proteínas de fenilalanil-alfa-ARNt sintetasas |
| CN103096925A (zh) | 2010-05-03 | 2013-05-08 | Atyr医药公司 | 与精氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| CN103108655B (zh) | 2010-05-03 | 2017-04-05 | Atyr 医药公司 | 与丝氨酰‑tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的创新发现 |
| CA2798301C (en) | 2010-05-04 | 2020-09-15 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutamyl-prolyl-trna synthetases |
| AU2011248101B2 (en) | 2010-05-04 | 2016-10-20 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex |
| US8945541B2 (en) | 2010-05-14 | 2015-02-03 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases |
| AU2011256366C1 (en) | 2010-05-17 | 2017-06-15 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
| EP2575857B1 (de) | 2010-06-01 | 2018-01-24 | aTyr Pharma, Inc. | Innovative erkennung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen in zusammenhang mit proteinfragmenten von lysyl-trna-synthetasen |
| CN103118695B (zh) | 2010-07-12 | 2016-08-03 | Atyr医药公司 | 与甘氨酰-tRNA合成酶的蛋白片段相关的治疗、诊断和抗体组合物的发现 |
| NZ603813A (en) | 2010-07-12 | 2015-03-27 | Atyr Pharma Inc | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
| WO2012009289A2 (en) | 2010-07-12 | 2012-01-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases |
| US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
| US9029506B2 (en) | 2010-08-25 | 2015-05-12 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-tRNA synthetases |
| EP2624857B1 (de) | 2010-10-06 | 2017-08-02 | aTyr Pharma, Inc. | Innovative entdeckung therapeutischer, diagnostischer und antikörperhaltiger zusammensetzungen im zusammenhang mit proteinfragmenten von tryptophanyl-trna-synthetasen |
| WO2012150286A1 (en) * | 2011-05-04 | 2012-11-08 | Borealis Ag | Polymer composition for electrical devices |
| RU2457837C1 (ru) * | 2011-07-15 | 2012-08-10 | Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук | КОМПЛЕКС ТРИС-(2-ГИДРОКСИЭТИЛ)АМИНА С БИС-(2-МЕТИЛФЕНОКСИАЦЕТАТОМ) ЦИНКА, ПОВЫШАЮЩИЙ ЦИТОКИННУЮ АКТИВНОСТЬ СУММАРНОЙ ТРИПТОФАНИЛ-тРНК-СИНТЕТАЗЫ |
| WO2013022982A2 (en) | 2011-08-09 | 2013-02-14 | Atyr Pharma, Inc. | Pegylated tyrosyl-trna synthetase polypeptides |
| WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
| WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
| AU2012368189B2 (en) | 2011-12-29 | 2017-08-31 | Atyr Pharma, Inc. | Aspartyl-tRNA synthetase-Fc conjugates |
| JP6170077B2 (ja) | 2012-02-16 | 2017-07-26 | エータイアー ファーマ， インコーポレイテッド | 自己免疫および炎症疾患を処置するためのヒスチジルｔＲＮＡ合成酵素 |
| JP6397479B2 (ja) | 2013-03-15 | 2018-09-26 | エータイアー ファーマ， インコーポレイテッド | ヒスチジル−ｔＲＮＡシンテターゼＦｃコンジュゲート |
| EP3116532A4 (de) * | 2014-03-13 | 2018-01-17 | National University of Singapore | Verfahren zur modulation von wars2 |
| DE102015110437B4 (de) * | 2015-06-29 | 2020-10-08 | Infineon Technologies Ag | Halbleitervorrichtung mit einer Metallstruktur, die mit einer leitfähigen Struktur elektrisch verbunden ist und Verfahren zur Herstellung |
| KR101771068B1 (ko) | 2015-07-14 | 2017-08-24 | 재단법인 의약바이오컨버젼스연구단 | 케모카인 활성을 가지는 신규한 폴리펩타이드 |
| AU2018256435B2 (en) | 2017-04-20 | 2025-03-13 | Atyr Pharma, Inc. | Compositions and methods for treating lung inflammation |
| WO2019236417A1 (en) | 2018-06-04 | 2019-12-12 | Biogen Ma Inc. | Anti-vla-4 antibodies having reduced effector function |
| WO2021010800A1 (ko) * | 2019-07-18 | 2021-01-21 | 제이더블유바이오사이언스 주식회사 | Wrs 단백질에 특이적으로 결합하는 항체 및 이의 용도 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3654090A (en) | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
| NL154598B (nl) | 1970-11-10 | 1977-09-15 | Organon Nv | Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking. |
| US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
| US4493795A (en) | 1983-10-17 | 1985-01-15 | Syntex (U.S.A.) Inc. | Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture |
| US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5885798A (en) * | 1996-08-28 | 1999-03-23 | Incyte Pharmaceuticals, Inc. | DNA encoding a monocyte activating cytokine |
| US7144984B2 (en) * | 2000-03-31 | 2006-12-05 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
| ATE473275T1 (de) | 2000-03-31 | 2010-07-15 | Scripps Research Inst | Menschliche aminoacyl-trna synthetase polypeptide zur regulation der angiogenese |
| US7273844B2 (en) | 2000-03-31 | 2007-09-25 | The Scripps Research Institute | Tryptophanyl-tRNA synthetase-derived polypeptides useful for the regulation of angiogenesis |
| US6903189B2 (en) * | 2001-03-21 | 2005-06-07 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
-
2001
- 2001-03-21 AT AT01918876T patent/ATE473275T1/de not_active IP Right Cessation
- 2001-03-21 AU AU2001250904A patent/AU2001250904B2/en not_active Ceased
- 2001-03-21 CA CA2404488A patent/CA2404488C/en not_active Expired - Lifetime
- 2001-03-21 JP JP2001572530A patent/JP4868681B2/ja not_active Expired - Lifetime
- 2001-03-21 AU AU5090401A patent/AU5090401A/xx active Pending
- 2001-03-21 AU AU2001245899A patent/AU2001245899B2/en not_active Ceased
- 2001-03-21 WO PCT/US2001/008975 patent/WO2001075078A1/en not_active Ceased
- 2001-03-21 WO PCT/US2001/008966 patent/WO2001074841A1/en not_active Ceased
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