IL151940A0 - HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS - Google Patents
HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESISInfo
- Publication number
- IL151940A0 IL151940A0 IL15194001A IL15194001A IL151940A0 IL 151940 A0 IL151940 A0 IL 151940A0 IL 15194001 A IL15194001 A IL 15194001A IL 15194001 A IL15194001 A IL 15194001A IL 151940 A0 IL151940 A0 IL 151940A0
- Authority
- IL
- Israel
- Prior art keywords
- trna synthetase
- useful
- angiogenesis
- regulation
- human aminoacyl
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
- C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/515—Angiogenesic factors; Angiogenin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- General Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Pain & Pain Management (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
Abstract
Compositions comprising truncated tryptophanyl-tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19347100P | 2000-03-31 | 2000-03-31 | |
PCT/US2001/008975 WO2001075078A1 (en) | 2000-03-31 | 2001-03-21 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPEPTIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
Publications (1)
Publication Number | Publication Date |
---|---|
IL151940A0 true IL151940A0 (en) | 2003-04-10 |
Family
ID=22713774
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15194001A IL151940A0 (en) | 2000-03-31 | 2001-03-21 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
IL15194301A IL151943A0 (en) | 2000-03-31 | 2001-03-21 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
IL151943A IL151943A (en) | 2000-03-31 | 2002-09-26 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
IL195677A IL195677A (en) | 2000-03-31 | 2008-12-02 | Nucleic acid encoding truncated tryptophanyl trna synthetase |
IL195854A IL195854A (en) | 2000-03-31 | 2008-12-10 | Human aminoacyl-trna synthetase polypetides useful for the regulation of angiogenesis |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL15194301A IL151943A0 (en) | 2000-03-31 | 2001-03-21 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
IL151943A IL151943A (en) | 2000-03-31 | 2002-09-26 | HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS |
IL195677A IL195677A (en) | 2000-03-31 | 2008-12-02 | Nucleic acid encoding truncated tryptophanyl trna synthetase |
IL195854A IL195854A (en) | 2000-03-31 | 2008-12-10 | Human aminoacyl-trna synthetase polypetides useful for the regulation of angiogenesis |
Country Status (10)
Country | Link |
---|---|
US (5) | US7067126B2 (en) |
EP (3) | EP1272506B1 (en) |
JP (2) | JP4868681B2 (en) |
AT (1) | ATE473275T1 (en) |
AU (6) | AU5090401A (en) |
CA (2) | CA2404484C (en) |
DE (1) | DE60142508D1 (en) |
IL (5) | IL151940A0 (en) |
NZ (2) | NZ522183A (en) |
WO (2) | WO2001074841A1 (en) |
Families Citing this family (62)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7273844B2 (en) * | 2000-03-31 | 2007-09-25 | The Scripps Research Institute | Tryptophanyl-tRNA synthetase-derived polypeptides useful for the regulation of angiogenesis |
US7144984B2 (en) * | 2000-03-31 | 2006-12-05 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
EP1272506B1 (en) * | 2000-03-31 | 2015-07-29 | The Scripps Research Institute | Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis |
CN100486992C (en) * | 2001-02-23 | 2009-05-13 | 斯克里普斯研究学院 | Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiongenesis |
US6903189B2 (en) * | 2001-03-21 | 2005-06-07 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
CA2497497A1 (en) * | 2002-09-04 | 2004-03-18 | Proteinexpress Co., Ltd. | Regulators for implantation |
ATE551060T1 (en) * | 2004-06-04 | 2012-04-15 | Scripps Research Inst | COMPOSITIONS AND METHODS FOR TREATING NEOVASCULAR DISEASES |
US20060079673A1 (en) * | 2004-08-02 | 2006-04-13 | Paul Glidden | Polynucleotides encoding tRNA synthetase fragments and uses thereof |
US8282921B2 (en) | 2004-08-02 | 2012-10-09 | Paul Glidden | tRNA synthetase fragments |
CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
JP2008520717A (en) * | 2004-11-19 | 2008-06-19 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | Treatment for multiple sclerosis |
JP5165389B2 (en) * | 2005-02-24 | 2013-03-21 | ザ スクリプス リサーチ インスティチュート | Revascularization of ischemic retinal tissue and screening method therefor |
WO2007064941A2 (en) | 2005-12-02 | 2007-06-07 | The Scripps Research Institute | Angiogenic tyrosyl trna synthetase compositions and methods |
MX2010010068A (en) * | 2008-03-11 | 2010-10-04 | Univ North Carolina | Angiostatic compositions comprising truncated tyrosyl-trna synthetase polypeptides and methods of using same. |
WO2009152247A2 (en) * | 2008-06-11 | 2009-12-17 | Atyr Pharma, Inc | Thrombopoietic activity of tyrosyl-trna synthetase polypeptides |
CN106434576A (en) | 2008-06-26 | 2017-02-22 | Atyr 医药公司 | Compositions and methods comprising glycyl-trna synthetases having non-canonical biological activities |
EP2403864B1 (en) | 2009-02-27 | 2015-08-12 | Atyr Pharma, Inc. | Polypeptide structural motifs associated with cell signaling activity |
US8510665B2 (en) * | 2009-03-16 | 2013-08-13 | Apple Inc. | Methods and graphical user interfaces for editing on a multifunction device with a touch screen display |
ES2742251T3 (en) | 2009-03-16 | 2020-02-13 | Pangu Biopharma Ltd | Compositions and methods comprising variants of histidyl tarn synthetase splicing that have non-canonical biological activities |
AU2010236913B2 (en) | 2009-03-31 | 2016-03-24 | Atyr Pharma, Inc. | Compositions and methods comprising aspartyl-tRNA synthetases having non-canonical biological activities |
WO2010121141A1 (en) * | 2009-04-17 | 2010-10-21 | Biogen Idec Ma Inc. | Compositions and methods to treat acute myelogenous leukemia |
US8828395B2 (en) | 2009-12-11 | 2014-09-09 | Atyr Pharma, Inc. | Antibodies that bind tyrosyl-tRNA synthetases |
US9127268B2 (en) | 2009-12-11 | 2015-09-08 | Atyr Pharma, Inc. | Aminoacyl tRNA synthetases for modulating inflammation |
WO2011072266A2 (en) * | 2009-12-11 | 2011-06-16 | Atyr Pharma, Inc. | Aminoacyl trna synthetases for modulating hematopoiesis |
US8828685B2 (en) | 2010-02-04 | 2014-09-09 | The Scripps Research Institute | Monomeric forms of human aminoacyl-t-RNA synthetases having non-canonical biological activities |
SI2558499T1 (en) | 2010-04-16 | 2017-08-31 | Biogen MA Inc., | Anti-vla-4 antibodies |
CA2797093C (en) | 2010-04-26 | 2019-10-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase |
CN103096910A (en) | 2010-04-27 | 2013-05-08 | Atyr医药公司 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl tRNA synthetases |
US8961960B2 (en) | 2010-04-27 | 2015-02-24 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
US8993723B2 (en) | 2010-04-28 | 2015-03-31 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl-tRNA synthetases |
WO2011139907A2 (en) | 2010-04-29 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases |
AU2011248490B2 (en) | 2010-04-29 | 2016-11-10 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Asparaginyl tRNA synthetases |
JP6039546B2 (en) | 2010-05-03 | 2016-12-07 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of seryl tRNA synthetase |
WO2011140135A2 (en) | 2010-05-03 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-trna synthetases |
EP2566495B1 (en) | 2010-05-03 | 2017-03-01 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-trna synthetases |
AU2011248355B2 (en) | 2010-05-03 | 2017-01-19 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of Arginyl-tRNA synthetases |
JP6008843B2 (en) | 2010-05-04 | 2016-10-19 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutamyl-prolyl tRNA synthetase |
EP2566499B1 (en) | 2010-05-04 | 2017-01-25 | aTyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex |
AU2011252990B2 (en) | 2010-05-14 | 2017-04-20 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-tRNA synthetases |
US9034598B2 (en) | 2010-05-17 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
JP6046607B2 (en) | 2010-05-27 | 2016-12-21 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutaminyl tRNA synthetase |
CN103118694B (en) | 2010-06-01 | 2016-08-03 | Atyr医药公司 | The discovery for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of lysyl-tRNA synzyme |
CA2804416C (en) | 2010-07-12 | 2020-04-28 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-trna synthetases |
KR102099730B1 (en) | 2010-07-12 | 2020-04-16 | 에이티와이알 파마, 인코포레이티드 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases |
CA2804424C (en) | 2010-07-12 | 2021-03-30 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases |
US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
CA2808539C (en) * | 2010-08-25 | 2021-05-25 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-trna synthetases |
WO2012048125A2 (en) * | 2010-10-06 | 2012-04-12 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases |
JP6425539B2 (en) * | 2011-05-04 | 2018-11-21 | ボレアリス エージー | Polymer composition for electrical devices |
RU2457837C1 (en) * | 2011-07-15 | 2012-08-10 | Федеральное государственное бюджетное учреждение науки Иркутский институт химии им. А.Е. Фаворского Сибирского отделения Российской академии наук | COMPLEX OF TRIS-(2-HYDROXYETHYL)AMINE WITH ZINK BIS-(2-METHYLPHENOXYACETATE), INCREASING CYTOKIN ACTIVITY OF TOTAL TRIPTOPHANYL-tRNA-SYNTHETASE |
WO2013022982A2 (en) | 2011-08-09 | 2013-02-14 | Atyr Pharma, Inc. | Pegylated tyrosyl-trna synthetase polypeptides |
WO2013086228A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Pegylated aspartyl-trna synthetase polypeptides |
WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
CN104220461A (en) | 2011-12-29 | 2014-12-17 | Atyr医药公司 | Aspartyl-trna synthetase-fc conjugates |
EP2814514B1 (en) | 2012-02-16 | 2017-09-13 | Atyr Pharma, Inc. | Histidyl-trna synthetases for treating autoimmune and inflammatory diseases |
AU2014233436B2 (en) | 2013-03-15 | 2019-12-05 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
US10160971B2 (en) | 2014-03-13 | 2018-12-25 | National University Of Singapore | Methods of modulating WARS2 |
DE102015110437B4 (en) * | 2015-06-29 | 2020-10-08 | Infineon Technologies Ag | Semiconductor device having a metal structure which is electrically connected to a conductive structure, and method of manufacturing |
KR101771068B1 (en) * | 2015-07-14 | 2017-08-24 | 재단법인 의약바이오컨버젼스연구단 | Novel polypeptide with chemokine activity |
EP3612215B1 (en) | 2017-04-20 | 2024-08-28 | aTyr Pharma, Inc. | Compositions for treating lung inflammation |
WO2019236417A1 (en) | 2018-06-04 | 2019-12-12 | Biogen Ma Inc. | Anti-vla-4 antibodies having reduced effector function |
EP4029882A4 (en) * | 2019-07-18 | 2023-08-16 | JW Bioscience | Antibody specifically binding to wrs protein, and use thereof |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3654090A (en) | 1968-09-24 | 1972-04-04 | Organon | Method for the determination of antigens and antibodies |
NL154598B (en) | 1970-11-10 | 1977-09-15 | Organon Nv | PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING. |
US4016043A (en) | 1975-09-04 | 1977-04-05 | Akzona Incorporated | Enzymatic immunological method for the determination of antigens and antibodies |
US4493795A (en) | 1983-10-17 | 1985-01-15 | Syntex (U.S.A.) Inc. | Synthetic peptide sequences useful in biological and pharmaceutical applications and methods of manufacture |
US4946778A (en) | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
US5885798A (en) * | 1996-08-28 | 1999-03-23 | Incyte Pharmaceuticals, Inc. | DNA encoding a monocyte activating cytokine |
US7144984B2 (en) | 2000-03-31 | 2006-12-05 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
EP1272506B1 (en) | 2000-03-31 | 2015-07-29 | The Scripps Research Institute | Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis |
US7273844B2 (en) | 2000-03-31 | 2007-09-25 | The Scripps Research Institute | Tryptophanyl-tRNA synthetase-derived polypeptides useful for the regulation of angiogenesis |
US6903189B2 (en) * | 2001-03-21 | 2005-06-07 | The Scripps Research Institute | Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis |
-
2001
- 2001-03-21 EP EP01924232.0A patent/EP1272506B1/en not_active Expired - Lifetime
- 2001-03-21 CA CA2404484A patent/CA2404484C/en not_active Expired - Lifetime
- 2001-03-21 AU AU5090401A patent/AU5090401A/en active Pending
- 2001-03-21 WO PCT/US2001/008966 patent/WO2001074841A1/en active Application Filing
- 2001-03-21 NZ NZ522183A patent/NZ522183A/en not_active IP Right Cessation
- 2001-03-21 AT AT01918876T patent/ATE473275T1/en not_active IP Right Cessation
- 2001-03-21 AU AU4589901A patent/AU4589901A/en active Pending
- 2001-03-21 JP JP2001572530A patent/JP4868681B2/en not_active Expired - Lifetime
- 2001-03-21 NZ NZ522182A patent/NZ522182A/en not_active IP Right Cessation
- 2001-03-21 CA CA2404488A patent/CA2404488C/en not_active Expired - Lifetime
- 2001-03-21 AU AU2001245899A patent/AU2001245899B2/en not_active Ceased
- 2001-03-21 IL IL15194001A patent/IL151940A0/en active IP Right Grant
- 2001-03-21 IL IL15194301A patent/IL151943A0/en unknown
- 2001-03-21 EP EP01918876A patent/EP1274834B1/en not_active Expired - Lifetime
- 2001-03-21 WO PCT/US2001/008975 patent/WO2001075078A1/en active Application Filing
- 2001-03-21 AU AU2001250904A patent/AU2001250904B2/en not_active Ceased
- 2001-03-21 US US10/240,532 patent/US7067126B2/en not_active Expired - Lifetime
- 2001-03-21 JP JP2001572952A patent/JP5036115B2/en not_active Expired - Fee Related
- 2001-03-21 EP EP10006915.2A patent/EP2258834B1/en not_active Expired - Lifetime
- 2001-03-21 DE DE60142508T patent/DE60142508D1/en not_active Expired - Lifetime
-
2002
- 2002-09-26 IL IL151943A patent/IL151943A/en unknown
-
2006
- 2006-06-01 US US11/444,924 patent/US7521215B2/en not_active Expired - Fee Related
- 2006-09-15 AU AU2006220352A patent/AU2006220352B2/en not_active Ceased
-
2008
- 2008-12-02 IL IL195677A patent/IL195677A/en active IP Right Grant
- 2008-12-10 IL IL195854A patent/IL195854A/en active IP Right Grant
-
2009
- 2009-04-17 US US12/386,428 patent/US7901917B2/en not_active Expired - Fee Related
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2010
- 2010-02-11 AU AU2010200514A patent/AU2010200514B2/en not_active Ceased
-
2011
- 2011-01-17 US US13/007,714 patent/US8148125B2/en not_active Expired - Fee Related
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2012
- 2012-03-30 US US13/434,933 patent/US8562977B2/en not_active Expired - Fee Related
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