IL151940A0 - HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS - Google Patents

HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS

Info

Publication number
IL151940A0
IL151940A0 IL15194001A IL15194001A IL151940A0 IL 151940 A0 IL151940 A0 IL 151940A0 IL 15194001 A IL15194001 A IL 15194001A IL 15194001 A IL15194001 A IL 15194001A IL 151940 A0 IL151940 A0 IL 151940A0
Authority
IL
Israel
Prior art keywords
trna synthetase
useful
angiogenesis
regulation
human aminoacyl
Prior art date
Application number
IL15194001A
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of IL151940A0 publication Critical patent/IL151940A0/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C07H21/04—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids with deoxyribosyl as saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/515—Angiogenesic factors; Angiogenin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Oncology (AREA)

Abstract

Compositions comprising truncated tryptophanyl-tRNA synthetase polypeptides useful for regulating angiogenesis, as well as nucleic acids encoding such tRNA synthetase polypeptides are described. Methods of making and using such compositions are also disclosed.
IL15194001A 2000-03-31 2001-03-21 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS IL151940A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19347100P 2000-03-31 2000-03-31
PCT/US2001/008975 WO2001075078A1 (en) 2000-03-31 2001-03-21 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPEPTIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS

Publications (1)

Publication Number Publication Date
IL151940A0 true IL151940A0 (en) 2003-04-10

Family

ID=22713774

Family Applications (5)

Application Number Title Priority Date Filing Date
IL15194001A IL151940A0 (en) 2000-03-31 2001-03-21 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS
IL15194301A IL151943A0 (en) 2000-03-31 2001-03-21 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS
IL151943A IL151943A (en) 2000-03-31 2002-09-26 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS
IL195677A IL195677A (en) 2000-03-31 2008-12-02 Nucleic acid encoding truncated tryptophanyl trna synthetase
IL195854A IL195854A (en) 2000-03-31 2008-12-10 Human aminoacyl-trna synthetase polypetides useful for the regulation of angiogenesis

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL15194301A IL151943A0 (en) 2000-03-31 2001-03-21 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS
IL151943A IL151943A (en) 2000-03-31 2002-09-26 HUMAN AMINOACYL-tRNA SYNTHETASE POLYPETIDES USEFUL FOR THE REGULATION OF ANGIOGENESIS
IL195677A IL195677A (en) 2000-03-31 2008-12-02 Nucleic acid encoding truncated tryptophanyl trna synthetase
IL195854A IL195854A (en) 2000-03-31 2008-12-10 Human aminoacyl-trna synthetase polypetides useful for the regulation of angiogenesis

Country Status (10)

Country Link
US (5) US7067126B2 (en)
EP (3) EP1272506B1 (en)
JP (2) JP4868681B2 (en)
AT (1) ATE473275T1 (en)
AU (6) AU5090401A (en)
CA (2) CA2404484C (en)
DE (1) DE60142508D1 (en)
IL (5) IL151940A0 (en)
NZ (2) NZ522183A (en)
WO (2) WO2001074841A1 (en)

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US7144984B2 (en) * 2000-03-31 2006-12-05 The Scripps Research Institute Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis
EP1272506B1 (en) * 2000-03-31 2015-07-29 The Scripps Research Institute Human aminoacyl-trna synthetase polypeptides useful for the regulation of angiogenesis
CN100486992C (en) * 2001-02-23 2009-05-13 斯克里普斯研究学院 Tryptophanyl-tRNA synthetase derived polypeptides useful for the regulation of angiongenesis
US6903189B2 (en) * 2001-03-21 2005-06-07 The Scripps Research Institute Human aminoacyl-tRNA synthetase polypeptides useful for the regulation of angiogenesis
CA2497497A1 (en) * 2002-09-04 2004-03-18 Proteinexpress Co., Ltd. Regulators for implantation
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US20060079673A1 (en) * 2004-08-02 2006-04-13 Paul Glidden Polynucleotides encoding tRNA synthetase fragments and uses thereof
US8282921B2 (en) 2004-08-02 2012-10-09 Paul Glidden tRNA synthetase fragments
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MX2010010068A (en) * 2008-03-11 2010-10-04 Univ North Carolina Angiostatic compositions comprising truncated tyrosyl-trna synthetase polypeptides and methods of using same.
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CN106434576A (en) 2008-06-26 2017-02-22 Atyr 医药公司 Compositions and methods comprising glycyl-trna synthetases having non-canonical biological activities
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Also Published As

Publication number Publication date
EP1274834A1 (en) 2003-01-15
IL195854A (en) 2015-01-29
AU2006220352B2 (en) 2009-11-12
JP2004500121A (en) 2004-01-08
AU4589901A (en) 2001-10-15
EP1272506A1 (en) 2003-01-08
AU5090401A (en) 2001-10-15
AU2001250904B2 (en) 2006-04-13
CA2404488A1 (en) 2001-10-11
NZ522183A (en) 2006-02-24
US20060216745A1 (en) 2006-09-28
IL151943A0 (en) 2003-04-10
CA2404488C (en) 2012-01-10
US20040009163A1 (en) 2004-01-15
JP2003529354A (en) 2003-10-07
IL151943A (en) 2009-08-03
EP1274834A4 (en) 2004-06-09
WO2001075078A1 (en) 2001-10-11
US8562977B2 (en) 2013-10-22
EP2258834B1 (en) 2015-09-23
EP1272506B1 (en) 2015-07-29
US7901917B2 (en) 2011-03-08
US20110110917A1 (en) 2011-05-12
JP4868681B2 (en) 2012-02-01
US20120263702A1 (en) 2012-10-18
JP5036115B2 (en) 2012-09-26
AU2001245899B2 (en) 2006-06-15
AU2010200514B2 (en) 2012-03-15
US8148125B2 (en) 2012-04-03
AU2010200514A1 (en) 2010-03-04
CA2404484A1 (en) 2001-10-11
EP1274834B1 (en) 2010-07-07
IL195677A (en) 2011-05-31
DE60142508D1 (en) 2010-08-19
NZ522182A (en) 2005-07-29
EP2258834A1 (en) 2010-12-08
US7067126B2 (en) 2006-06-27
ATE473275T1 (en) 2010-07-15
AU2006220352A1 (en) 2006-10-12
CA2404484C (en) 2017-04-18
US20090227662A1 (en) 2009-09-10
US7521215B2 (en) 2009-04-21
EP1272506A4 (en) 2004-06-02
WO2001074841A1 (en) 2001-10-11

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