ATE473014T1 - Immunmodulator mit ganzzell-tsukamurella bakterien - Google Patents

Immunmodulator mit ganzzell-tsukamurella bakterien

Info

Publication number
ATE473014T1
ATE473014T1 AT04798504T AT04798504T ATE473014T1 AT E473014 T1 ATE473014 T1 AT E473014T1 AT 04798504 T AT04798504 T AT 04798504T AT 04798504 T AT04798504 T AT 04798504T AT E473014 T1 ATE473014 T1 AT E473014T1
Authority
AT
Austria
Prior art keywords
tsukamurella
bacteria
whole cell
immune modulator
modulator
Prior art date
Application number
AT04798504T
Other languages
English (en)
Inventor
Graham Mcintyre
John Lawson Stanford
Cynthia Ann Stanford
Oscar Adelmo Bottasso
Original Assignee
Ucl Business Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0326620A external-priority patent/GB0326620D0/en
Priority claimed from GB0404102A external-priority patent/GB0404102D0/en
Application filed by Ucl Business Plc filed Critical Ucl Business Plc
Application granted granted Critical
Publication of ATE473014T1 publication Critical patent/ATE473014T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/0008—Antigens related to auto-immune diseases; Preparations to induce self-tolerance
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/05—Actinobacteria, e.g. Actinomyces, Streptomyces, Nocardia, Bifidobacterium, Gardnerella, Corynebacterium; Propionibacterium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521—Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55588—Adjuvants of undefined constitution
    • A61K2039/55594—Adjuvants of undefined constitution from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Vascular Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT04798504T 2003-11-14 2004-11-12 Immunmodulator mit ganzzell-tsukamurella bakterien ATE473014T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0326620A GB0326620D0 (en) 2003-11-14 2003-11-14 Immune modulator
GB0404102A GB0404102D0 (en) 2004-02-24 2004-02-24 Immune modulator
PCT/GB2004/004783 WO2005049056A2 (en) 2003-11-14 2004-11-12 Immune modulator comprising whole cell rhodococcus, gordonia, nocardia, dietzia, tsukamurella or nocardioides bacteria

Publications (1)

Publication Number Publication Date
ATE473014T1 true ATE473014T1 (de) 2010-07-15

Family

ID=34621659

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04798504T ATE473014T1 (de) 2003-11-14 2004-11-12 Immunmodulator mit ganzzell-tsukamurella bakterien

Country Status (9)

Country Link
US (1) US7413728B2 (de)
EP (1) EP1684803B1 (de)
JP (1) JP4875494B2 (de)
AR (1) AR046583A1 (de)
AT (1) ATE473014T1 (de)
DE (1) DE602004028038D1 (de)
ES (1) ES2347566T3 (de)
GB (1) GB2422544B (de)
WO (1) WO2005049056A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9107864B2 (en) 2004-06-07 2015-08-18 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US8501198B2 (en) 2004-06-07 2013-08-06 Qu Biologics Inc. Tissue targeted antigenic activation of the immune response to treat cancers
US7442374B2 (en) 2004-07-19 2008-10-28 Ucl Biomedica Plc Composition for increasing the survival to slaughter rate of piglets
GB0526033D0 (en) 2005-12-21 2006-02-01 Bioeos Ltd Method
GB0526032D0 (en) * 2005-12-21 2006-02-01 Bioeos Ltd Use
US8278063B2 (en) * 2007-06-29 2012-10-02 Commonwealth Scientific And Industrial Research Organisation Methods for degrading toxic compounds
GB0716778D0 (en) 2007-08-29 2007-10-10 Bioeos Ltd Use
US20110092589A1 (en) * 2008-03-10 2011-04-21 The Charlotte-Mecklenburg Hospotal Authority Treatment of Inflammatory Conditions and Diseases with Metal-Thiols
US8980279B2 (en) 2010-07-26 2015-03-17 Qu Biologics Personalized site-specific immunomodulation
KR102157718B1 (ko) * 2010-07-26 2020-09-18 큐 바이올로직스 인코포레이티드 면역원성 소염 조성물
AU2015252726B2 (en) 2014-05-02 2020-12-24 Qu Biologics Inc. Anti-microbial immunomodulation
CN109414463A (zh) * 2016-02-25 2019-03-01 托马斯·朱利叶斯·波洛迪 治疗慢性传染性疾病的组合物和方法
EP3913045A4 (de) * 2019-01-15 2022-12-28 Liaoning Greatest Bio-Pharmaceutical Co., Ltd. Aus rhodococcus ruber stammendes produkt und seine pharmazeutische verwendung

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71683A0 (en) * 1984-04-27 1984-09-30 Yeda Res & Dev Pharmaceutical compositions for treating arthritis type diseases comprising fractions obtained from mycobacteria
US4599310A (en) * 1984-06-18 1986-07-08 Bristol-Myers Company Process for producing antitumor antibiotic compound
GB9203814D0 (en) * 1992-02-21 1992-04-08 Univ London Treatment of long term auto-immune conditions
WO1996012035A1 (en) * 1994-10-12 1996-04-25 E.I. Du Pont De Nemours And Company Enzymatic process for the preparation of chiral-alpha-tertiary carboxylic acid esters
JPH10117633A (ja) * 1996-10-21 1998-05-12 Mitsui Pharmaceut Inc 遺伝子欠損動物
KR100250830B1 (ko) * 1997-12-09 2000-04-01 성재갑 자가분해에 의해 폴리하이드록시알킨산으로부터 광학활성을 가진 단량체 하이드록시카르복실산의 제조방법
AU3344299A (en) * 1998-04-20 1999-11-08 Shionogi & Co., Ltd. Th2-migration promoters containing w/o emulsions
ES2216516T3 (es) * 1998-05-20 2004-10-16 Erasmus Universiteit Rotterdam Inmunorregulador.
JPWO2002056911A1 (ja) * 2000-12-26 2004-05-20 味の素株式会社 移植拒絶反応抑制剤
EP1450837A4 (de) * 2001-08-07 2006-01-04 Immunex Corp Interleukin-1-rezeptoren bei der behandlung von krankheiten
KR101048798B1 (ko) * 2001-12-11 2011-07-15 앵스티띠 나셔날 드 라 쌍뜨 에 드 라 르셰르슈 메디깔 면역조절곤란증을 포함하는 질병을 치료하기 위한그람양성균 제제
AU2003263319B2 (en) * 2002-09-06 2009-07-02 University College London Whole bacterial cells as immune modulator

Also Published As

Publication number Publication date
JP4875494B2 (ja) 2012-02-15
WO2005049056A3 (en) 2005-11-03
GB2422544B (en) 2008-05-14
EP1684803A2 (de) 2006-08-02
US20070104735A1 (en) 2007-05-10
WO2005049056A2 (en) 2005-06-02
GB2422544A (en) 2006-08-02
EP1684803B1 (de) 2010-07-07
JP2007511493A (ja) 2007-05-10
ES2347566T3 (es) 2010-11-02
AR046583A1 (es) 2005-12-14
US7413728B2 (en) 2008-08-19
GB0607956D0 (en) 2006-05-31
DE602004028038D1 (de) 2010-08-19

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Legal Events

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