ATE471203T1 - Verfahren und vorrichtung zur grösssenabhängigen trennung von mikro- und nanopartikeln - Google Patents
Verfahren und vorrichtung zur grösssenabhängigen trennung von mikro- und nanopartikelnInfo
- Publication number
- ATE471203T1 ATE471203T1 AT99945612T AT99945612T ATE471203T1 AT E471203 T1 ATE471203 T1 AT E471203T1 AT 99945612 T AT99945612 T AT 99945612T AT 99945612 T AT99945612 T AT 99945612T AT E471203 T1 ATE471203 T1 AT E471203T1
- Authority
- AT
- Austria
- Prior art keywords
- particles
- solvent
- filter
- antisolvent
- processes
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
- B01D11/0407—Solvent extraction of solutions which are liquid with a supercritical fluid the supercritical fluid acting as solvent for the solute
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0403—Solvent extraction of solutions which are liquid with a supercritical fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/04—Solvent extraction of solutions which are liquid
- B01D11/0415—Solvent extraction of solutions which are liquid in combination with membranes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B29/00—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape
- C30B29/60—Single crystals or homogeneous polycrystalline material with defined structure characterised by the material or by their shape characterised by shape
- C30B29/605—Products containing multiple oriented crystallites, e.g. columnar crystallites
-
- C—CHEMISTRY; METALLURGY
- C30—CRYSTAL GROWTH
- C30B—SINGLE-CRYSTAL GROWTH; UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL OR UNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL; REFINING BY ZONE-MELTING OF MATERIAL; PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE; APPARATUS THEREFOR
- C30B7/00—Single-crystal growth from solutions using solvents which are liquid at normal temperature, e.g. aqueous solutions
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Water Supply & Treatment (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Metallurgy (AREA)
- Organic Chemistry (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Inorganic Compounds Of Heavy Metals (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/193,660 US6113795A (en) | 1998-11-17 | 1998-11-17 | Process and apparatus for size selective separation of micro- and nano-particles |
PCT/US1999/020651 WO2000029096A1 (en) | 1998-11-17 | 1999-09-09 | Process and apparatus for size selective separation of micro- and nano-particles |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE471203T1 true ATE471203T1 (de) | 2010-07-15 |
Family
ID=22714508
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99945612T ATE471203T1 (de) | 1998-11-17 | 1999-09-09 | Verfahren und vorrichtung zur grösssenabhängigen trennung von mikro- und nanopartikeln |
Country Status (7)
Country | Link |
---|---|
US (1) | US6113795A (de) |
EP (1) | EP1133345B1 (de) |
AT (1) | ATE471203T1 (de) |
AU (1) | AU753461B2 (de) |
CA (1) | CA2351523C (de) |
DE (1) | DE69942508D1 (de) |
WO (1) | WO2000029096A1 (de) |
Families Citing this family (78)
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---|---|---|---|---|
US6143211A (en) * | 1995-07-21 | 2000-11-07 | Brown University Foundation | Process for preparing microparticles through phase inversion phenomena |
FR2761899B1 (fr) * | 1997-04-15 | 1999-05-28 | Commissariat Energie Atomique | Procede et installation de filtration tangentielle d'un liquide visqueux |
US6402689B1 (en) | 1998-09-30 | 2002-06-11 | Sicel Technologies, Inc. | Methods, systems, and associated implantable devices for dynamic monitoring of physiological and biological properties of tumors |
FR2794379B1 (fr) * | 1999-06-04 | 2002-06-07 | Separex Sa | Dispositif de fractionnement de melanges a membrane operant a pression supercritique |
US6914105B1 (en) | 1999-11-12 | 2005-07-05 | North Carolina State University | Continuous process for making polymers in carbon dioxide |
FR2803539B1 (fr) * | 2000-01-07 | 2002-07-12 | Separex Sa | Procede de captage et d'encapsulation de fines particules |
ES2170008B1 (es) * | 2000-08-25 | 2003-05-01 | Soc Es Carburos Metalicos Sa | Procedimiento para la precipitacion de particulas solidas finamente divididas. |
US6562952B1 (en) * | 2000-10-31 | 2003-05-13 | The University Of Kansas | Precipitation of proteins from organic solutions |
US6685841B2 (en) | 2001-02-14 | 2004-02-03 | Gabriel P. Lopez | Nanostructured devices for separation and analysis |
US6913697B2 (en) | 2001-02-14 | 2005-07-05 | Science & Technology Corporation @ Unm | Nanostructured separation and analysis devices for biological membranes |
US20030051728A1 (en) | 2001-06-05 | 2003-03-20 | Lloyd Peter M. | Method and device for delivering a physiologically active compound |
US7645442B2 (en) | 2001-05-24 | 2010-01-12 | Alexza Pharmaceuticals, Inc. | Rapid-heating drug delivery article and method of use |
US20070122353A1 (en) | 2001-05-24 | 2007-05-31 | Hale Ron L | Drug condensation aerosols and kits |
US7458374B2 (en) | 2002-05-13 | 2008-12-02 | Alexza Pharmaceuticals, Inc. | Method and apparatus for vaporizing a compound |
WO2003013683A1 (en) * | 2001-08-08 | 2003-02-20 | Brown University Research Foundation | Methods for micronization of hydrophobic drugs |
IL160927A0 (en) * | 2001-10-15 | 2004-08-31 | Crititech Inc | Compositions and methods for delivery of poorly water soluble drugs and method of treatment |
US20030150085A1 (en) * | 2002-02-08 | 2003-08-14 | Lalit Chordia | Manipulation of solvent properties for particle formation |
US7128840B2 (en) * | 2002-03-26 | 2006-10-31 | Idaho Research Foundation, Inc. | Ultrasound enhanced process for extracting metal species in supercritical fluids |
US20040115345A1 (en) * | 2002-07-23 | 2004-06-17 | Xueying Huang | Nanoparticle fractionation and size determination |
US6916389B2 (en) | 2002-08-13 | 2005-07-12 | Nanotechnologies, Inc. | Process for mixing particulates |
US7507530B2 (en) * | 2002-08-27 | 2009-03-24 | E. I. Du Pont De Nemours And Company | Nanoparticle complexes having a defined number of ligands |
US20040105818A1 (en) | 2002-11-26 | 2004-06-03 | Alexza Molecular Delivery Corporation | Diuretic aerosols and methods of making and using them |
US7913688B2 (en) | 2002-11-27 | 2011-03-29 | Alexza Pharmaceuticals, Inc. | Inhalation device for producing a drug aerosol |
JP5129926B2 (ja) * | 2002-12-12 | 2013-01-30 | インテグリス・インコーポレーテッド | 多孔質焼結コンポジット材料 |
GB0229714D0 (en) * | 2002-12-20 | 2003-01-29 | Glaxo Group Ltd | Novel apparatus and method |
US20040154528A1 (en) * | 2003-02-11 | 2004-08-12 | Page Robert E. | Method for making synthetic gems comprising elements recovered from humans or animals and the product thereof |
US7455797B2 (en) * | 2003-02-28 | 2008-11-25 | Ferro Corporation | Method and apparatus for producing particles using supercritical fluid |
AU2004234057A1 (en) * | 2003-04-29 | 2004-11-11 | Akzo Nobel N.V. | Antisolvent solidification process |
WO2004104490A1 (en) | 2003-05-21 | 2004-12-02 | Alexza Pharmaceuticals, Inc. | Self-contained heating unit and drug-supply unit employing same |
US7171922B2 (en) * | 2003-05-30 | 2007-02-06 | G.H.L. International, Inc. | Cat scratching post |
US7465381B2 (en) * | 2004-01-22 | 2008-12-16 | Stc.Unm | Electrokinetic molecular separation in nanoscale fluidic channels |
US7582275B1 (en) | 2004-01-26 | 2009-09-01 | The United States Of America As Represented By The Secretary Of The Air Force | Method of processing filamentary nanocarbon |
US20060065528A1 (en) * | 2004-02-03 | 2006-03-30 | Gabriel Lopez | Nanostructured devices for separation and analysis |
EP1742615A2 (de) * | 2004-05-05 | 2007-01-17 | Akzo Nobel N.V. | Antilösungsmittel-emulsions-solidifikationsverfahren |
US20090004277A1 (en) * | 2004-05-18 | 2009-01-01 | Franchini Miriam K | Nanoparticle dispersion containing lactam compound |
US7540286B2 (en) | 2004-06-03 | 2009-06-02 | Alexza Pharmaceuticals, Inc. | Multiple dose condensation aerosol devices and methods of forming condensation aerosols |
US8105471B1 (en) | 2004-07-19 | 2012-01-31 | Han Sang M | Nanofluidics for bioseparation and analysis |
EP1809793A2 (de) * | 2004-09-27 | 2007-07-25 | Auburn University | Auswahl und abscheidung von nanopartikeln mittels co2-expandierter flüssigkeiten |
US20060201342A1 (en) * | 2005-03-01 | 2006-09-14 | Paganessi Joseph E | Use of porous metal membrane for treating liquid foods |
US8240190B2 (en) * | 2005-08-23 | 2012-08-14 | Uwm Research Foundation, Inc. | Ambient-temperature gas sensor |
US8268405B2 (en) * | 2005-08-23 | 2012-09-18 | Uwm Research Foundation, Inc. | Controlled decoration of carbon nanotubes with aerosol nanoparticles |
US20080066624A1 (en) * | 2006-04-06 | 2008-03-20 | Alex Taylor | Sous vide cooker with integrated immersion circulator |
ES2472699T3 (es) * | 2006-10-11 | 2014-07-02 | Crititech, Inc. | Aparato para precipitación de partículas pequeñas de medicamento en recipientes de uso |
ES2594867T3 (es) | 2007-03-09 | 2016-12-23 | Alexza Pharmaceuticals, Inc. | Unidad de calentamiento para usar en un dispositivo de administración de fármaco |
JP2010534563A (ja) * | 2007-07-24 | 2010-11-11 | ネクスバイオ,インク. | マイクロ粒子の作製のための技術 |
US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
US8367427B2 (en) | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US8323615B2 (en) | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8215489B1 (en) * | 2008-10-31 | 2012-07-10 | Auburn University | Method and apparatus for physical separation of different sized nanostructures |
IN2012DN02978A (de) * | 2009-09-08 | 2015-07-31 | Michael R Eades | |
US8702844B2 (en) * | 2011-04-18 | 2014-04-22 | Phillips 66 Company | Particle doped hollow-fiber contactor |
JP2015527310A (ja) | 2012-06-28 | 2015-09-17 | アンサン バイオファーマ, インコーポレイテッドAnsun Biopharma, Inc. | 下気道および中枢気道への送達用微粒子製剤ならびに製造方法 |
US8778181B1 (en) | 2013-03-14 | 2014-07-15 | Crititech, Inc. | Equipment assembly for and method of processing particles |
AU2015261576B2 (en) * | 2013-03-14 | 2016-07-28 | Crititech, Inc | Equipment assembly and method of processing particles |
US9925512B2 (en) | 2013-03-14 | 2018-03-27 | Crititech, Inc. | Equipment assembly for and method of processing particles |
SG10201913945QA (en) | 2015-06-04 | 2020-03-30 | Crititech Inc | Taxane particles and their use |
RU2018113280A (ru) | 2015-09-16 | 2019-10-16 | ДиЭфБи СОРИА, ЭлЭлСи | Доставка наночастиц лекарственного средства и способы их использования |
USD821134S1 (en) | 2016-02-02 | 2018-06-26 | Eades Appliance Technology, Llc | Cooker |
USD817068S1 (en) | 2016-02-02 | 2018-05-08 | Eades Appliance Technology, Llc | Cooker |
USD816396S1 (en) | 2016-02-02 | 2018-05-01 | Eades Appliance Technology, Llc | Cooker lid |
JP6970683B2 (ja) | 2016-04-04 | 2021-11-24 | クリティテック・インコーポレイテッド | 固形腫瘍治療のための方法 |
US20180244535A1 (en) * | 2017-02-24 | 2018-08-30 | BWXT Isotope Technology Group, Inc. | Titanium-molybdate and method for making the same |
US11363709B2 (en) | 2017-02-24 | 2022-06-14 | BWXT Isotope Technology Group, Inc. | Irradiation targets for the production of radioisotopes |
WO2018162271A1 (en) | 2017-03-05 | 2018-09-13 | Rita Dobmeyer | Nanoparticles for the treatment of macular degeneration |
WO2018170210A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of vulvar intraepithelial neoplasia (vin) and genital warts using nanoparticles of taxanes |
WO2018170207A1 (en) | 2017-03-15 | 2018-09-20 | Dfb Soria, Llc | Topical therapy for the treatment of skin keratoses using nanoparticles of taxanes |
EP3595633B1 (de) | 2017-03-15 | 2023-07-05 | DFB Soria, LLC | Topische therapie zur behandlung von hautmalignitäten mit taxan nanopartikeln |
WO2018227037A1 (en) | 2017-06-09 | 2018-12-13 | Crititech, Inc. | Treatment of epithelial cysts by intracystic injection of antineoplastic particles |
US10398646B2 (en) | 2017-06-14 | 2019-09-03 | Crititech, Inc. | Methods for treating lung disorders |
BR112020005814A2 (pt) | 2017-10-03 | 2020-09-24 | Crititech, Inc. | administração local de partículas antineoplásicas em combinação com administração sistêmica de agentes imunoterapêuticos para o tratamento de câncer |
SG11202005672PA (en) | 2018-01-05 | 2020-07-29 | Crititech Inc | Treatment of bladder cancer by local administration of taxane particles |
CA3092500A1 (en) | 2018-03-16 | 2019-09-19 | Dfb Soria, Llc | Topical therapy for the treatment of cervical intraepithelial neoplasia (cin) and cervical cancer using nanoparticles of taxanes |
DE102018110804B4 (de) * | 2018-05-04 | 2024-06-27 | Umicore Ag & Co. Kg | Beschichteter Wandflussfilter |
US20190365699A1 (en) | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Treatment of Kidney Tumors by Intratumoral Injection of Taxane Particles |
AU2019276718A1 (en) | 2018-05-31 | 2020-10-01 | Crititech, Inc. | Methods for isolating tumor-specific immune cells from a subject for adoptive cell therapy and cancer vaccines |
WO2019231499A1 (en) | 2018-05-31 | 2019-12-05 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for treatment of cancer |
WO2020072090A1 (en) | 2018-10-03 | 2020-04-09 | Crititech, Inc. | Use of antineoplastic agents to stimulate the immune system for production of tertiary lymphoid structures (tls) |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL236452A (de) * | 1958-02-24 | 1900-01-01 | ||
US4186100A (en) * | 1976-12-13 | 1980-01-29 | Mott Lambert H | Inertial filter of the porous metal type |
FR2598717B1 (fr) * | 1986-05-14 | 1988-08-26 | Inst Francais Du Petrole | Procede de desasphaltage d'une huile d'hydrocarbure renfermant de l'asphalte |
US5707634A (en) * | 1988-10-05 | 1998-01-13 | Pharmacia & Upjohn Company | Finely divided solid crystalline powders via precipitation into an anti-solvent |
US4958529A (en) * | 1989-11-22 | 1990-09-25 | Vestec Corporation | Interface for coupling liquid chromatography to solid or gas phase detectors |
WO1993002969A1 (en) * | 1991-08-09 | 1993-02-18 | Board Of Regents, The University Of Texas System | High temperature wet oxidation using sintered separators |
US5160044A (en) * | 1992-02-20 | 1992-11-03 | National Tsing Hua University | Process for separating ethanol from aqueous solution |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
FR2693921B1 (fr) * | 1992-07-24 | 1994-09-30 | Tech Sep | Support monolithe céramique pour membrane de filtration tangentielle. |
AU5171293A (en) * | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
GB9313642D0 (en) * | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
WO1995013132A1 (en) * | 1993-11-08 | 1995-05-18 | The Gillette Company | Method of forming particles using a supercritical fluid, aerogel particles formed thereby, and antiperspirants containing aerogel particles |
US5430224A (en) * | 1994-04-15 | 1995-07-04 | Exxon Research & Engineering Company | Supercritical perstraction process |
FR2727873B1 (fr) * | 1994-12-12 | 1997-01-10 | Commissariat Energie Atomique | Procede et installation de separation de composes lourds et legers par extraction par un fluide supercritique et nanofiltration |
US5803966A (en) * | 1995-11-01 | 1998-09-08 | Alcon Laboratories, Inc. | Process for sizing prednisolone acetate using a supercritical fluid anti-solvent |
US5833891A (en) * | 1996-10-09 | 1998-11-10 | The University Of Kansas | Methods for a particle precipitation and coating using near-critical and supercritical antisolvents |
-
1998
- 1998-11-17 US US09/193,660 patent/US6113795A/en not_active Expired - Lifetime
-
1999
- 1999-09-09 WO PCT/US1999/020651 patent/WO2000029096A1/en active IP Right Grant
- 1999-09-09 DE DE69942508T patent/DE69942508D1/de not_active Expired - Lifetime
- 1999-09-09 CA CA002351523A patent/CA2351523C/en not_active Expired - Lifetime
- 1999-09-09 AU AU58183/99A patent/AU753461B2/en not_active Expired
- 1999-09-09 AT AT99945612T patent/ATE471203T1/de not_active IP Right Cessation
- 1999-09-09 EP EP99945612A patent/EP1133345B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU5818399A (en) | 2000-06-05 |
EP1133345B1 (de) | 2010-06-16 |
CA2351523A1 (en) | 2000-05-25 |
CA2351523C (en) | 2007-10-30 |
DE69942508D1 (de) | 2010-07-29 |
EP1133345A4 (de) | 2005-09-07 |
US6113795A (en) | 2000-09-05 |
WO2000029096A1 (en) | 2000-05-25 |
AU753461B2 (en) | 2002-10-17 |
EP1133345A1 (de) | 2001-09-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |