ATE462800T1 - Vorhersage von entzündlichen krankeiten assoziert mit il-1 genlocus polymorphismen - Google Patents
Vorhersage von entzündlichen krankeiten assoziert mit il-1 genlocus polymorphismenInfo
- Publication number
- ATE462800T1 ATE462800T1 AT98922938T AT98922938T ATE462800T1 AT E462800 T1 ATE462800 T1 AT E462800T1 AT 98922938 T AT98922938 T AT 98922938T AT 98922938 T AT98922938 T AT 98922938T AT E462800 T1 ATE462800 T1 AT E462800T1
- Authority
- AT
- Austria
- Prior art keywords
- genlocus
- polymorphisms
- prediction
- inflammatory diseases
- diseases associated
- Prior art date
Links
- 108010002352 Interleukin-1 Proteins 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 102000054765 polymorphisms of proteins Human genes 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
- Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
- Y10T436/143333—Saccharide [e.g., DNA, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Physiology (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9711040.7A GB9711040D0 (en) | 1997-05-29 | 1997-05-29 | Prediction of inflammatory disease |
| PCT/GB1998/001481 WO1998054359A1 (en) | 1997-05-29 | 1998-05-21 | Prediction of inflammatory disease associated with il-1 geneloci polymorphisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE462800T1 true ATE462800T1 (de) | 2010-04-15 |
Family
ID=10813199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98922938T ATE462800T1 (de) | 1997-05-29 | 1998-05-21 | Vorhersage von entzündlichen krankeiten assoziert mit il-1 genlocus polymorphismen |
Country Status (19)
| Country | Link |
|---|---|
| US (4) | US6268142B1 (https=) |
| EP (1) | EP0983385B1 (https=) |
| JP (1) | JP2002500513A (https=) |
| CN (1) | CN1177059C (https=) |
| AR (1) | AR016754A1 (https=) |
| AT (1) | ATE462800T1 (https=) |
| AU (1) | AU755107B2 (https=) |
| BR (1) | BR9809183A (https=) |
| CA (1) | CA2291731A1 (https=) |
| DE (1) | DE69841588D1 (https=) |
| EA (1) | EA199901097A1 (https=) |
| ES (1) | ES2342992T3 (https=) |
| GB (1) | GB9711040D0 (https=) |
| IL (1) | IL133128A0 (https=) |
| NO (1) | NO995803L (https=) |
| PL (1) | PL337080A1 (https=) |
| TW (1) | TWI236502B (https=) |
| WO (1) | WO1998054359A1 (https=) |
| ZA (1) | ZA984490B (https=) |
Families Citing this family (97)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6524795B1 (en) * | 1997-03-10 | 2003-02-25 | Interleukin Genetics, Inc. | Diagnostics for cardiovascular disorders |
| US6720141B1 (en) * | 1999-11-01 | 2004-04-13 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for restenosis |
| US7820383B2 (en) | 1997-03-10 | 2010-10-26 | Interleukin Genetics, Inc. | Method for diagnosing myocardial infarction |
| US20050282198A1 (en) * | 1997-05-29 | 2005-12-22 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for diseases associated with an IL-1 inflammatory haplotype |
| GB9711040D0 (en) | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| IL135957A0 (en) * | 1997-11-07 | 2001-05-20 | Interleukin Genetics Inc | Diagnostics and therapeutics for chronic obstructive airway disease |
| US6746839B1 (en) | 1998-01-12 | 2004-06-08 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for an obstructive airway disease |
| US20050032077A1 (en) * | 1998-03-10 | 2005-02-10 | Duff Gordon W. | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| GB2336431B (en) * | 1998-04-17 | 2003-06-25 | Johnson & Johnson Medical Ltd | Method of analysis of chronic wounds |
| US6733967B1 (en) | 1998-04-21 | 2004-05-11 | Interleukin Genetics, Inc. | Fetal testing for prediction of low birth weight |
| EP1071822A2 (en) * | 1998-04-21 | 2001-01-31 | Interleukin Genetics, Inc. | Fetal testing for prediction of low birth weight |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| IL144492A0 (en) * | 1999-02-10 | 2002-05-23 | Interleukin Genetics Inc | Therapeutics and diagnostics based on an il-1b mutation |
| AU779701B2 (en) * | 1999-04-02 | 2005-02-10 | Interleukin Genetics, Inc. | Prediction of risk of interstitial lung disease |
| IL147182A0 (en) * | 1999-06-30 | 2002-08-14 | Interleukin Genetics Inc | Diagnostics and therapeutics for diseases associated with an il-1 inflammatory haplorype |
| EP1212464B1 (en) * | 1999-08-30 | 2006-02-22 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for osteoporosis |
| US20090023147A1 (en) * | 1999-08-30 | 2009-01-22 | Kenneth Kornman | Diagnostics and therapeutics for osteoporosis |
| US20030054002A1 (en) * | 2000-05-17 | 2003-03-20 | Board Of Regents, The University Of Texas System | Isolation of genes within SLE-1B that mediate a break in immune tolerance |
| WO2002000933A2 (en) * | 2000-06-23 | 2002-01-03 | Interleukin Genetics, Inc. | Screening assays for identifying modulators of the inflammatory or immune responses |
| US20020168639A1 (en) * | 2000-09-22 | 2002-11-14 | Muraca Patrick J. | Profile array substrates |
| JP2002345500A (ja) * | 2000-12-22 | 2002-12-03 | Pfizer Prod Inc | 炎症性障害を発展させる増加したリスクを検出するための方法および試薬 |
| EP1801240A1 (en) * | 2001-06-05 | 2007-06-27 | Auckland Uniservices Limited | Methods and compositions for assessment of pulmonary function and disorders |
| AU2002320100A1 (en) * | 2001-06-15 | 2003-01-02 | Interleukin Genetics, Inc. | Methods for detecting and treating the early onset of aging-related conditions |
| WO2003072827A1 (en) * | 2001-10-31 | 2003-09-04 | Children's Hospital Medical Center | Method for diagnosis and treatment of rheumatoid arthritis |
| US20080311581A1 (en) * | 2001-11-19 | 2008-12-18 | David Wyllie | Functional polymorphisms of the interleukin-1 locus affecting transcription and susceptibility to inflammatory and infectious diseases |
| CN1753903B (zh) | 2001-11-19 | 2010-05-12 | 白介素遗传公司 | 影响转录和对炎性和传染性疾病的敏感性的白细胞介素-1基因座的功能多态性 |
| CA2473641A1 (en) * | 2002-01-25 | 2003-08-07 | Interleukin Genetics, Inc. | The il-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| US20070264645A1 (en) * | 2002-01-25 | 2007-11-15 | Kenneth Kornman | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| US20040048287A1 (en) * | 2002-05-20 | 2004-03-11 | Smith Lloyd M. | Label-free detection of single nucleotide polymorphisms using surface plasmon resonance imaging |
| US9388459B2 (en) * | 2002-06-17 | 2016-07-12 | Affymetrix, Inc. | Methods for genotyping |
| KR20040001552A (ko) * | 2002-06-28 | 2004-01-07 | 주식회사 인투젠 | 디엔에이 결합 단백질 비에 대한 자가항체에 결합할 수있는 단백질을 유효 성분으로 함유하는 전신성 경화증진단용 조성물, 이를 이용한 상기 자가항체의 검출 방법및 전신성 경화증 진단 방법 |
| US20040229228A1 (en) * | 2002-07-25 | 2004-11-18 | Northwestern University | Il-1 genotype in early kidney allograft rejection |
| ES2302959T3 (es) * | 2002-09-30 | 2008-08-01 | Novartis Ag | Metodos para predecir elevacion del colesterol durante una terapia inmunodepresora. |
| CN1711361A (zh) * | 2002-10-15 | 2005-12-21 | 诺瓦提斯公司 | 预测药物治疗副效应水肿的方法 |
| US10229244B2 (en) | 2002-11-11 | 2019-03-12 | Affymetrix, Inc. | Methods for identifying DNA copy number changes using hidden markov model based estimations |
| US7822555B2 (en) | 2002-11-11 | 2010-10-26 | Affymetrix, Inc. | Methods for identifying DNA copy number changes |
| CA2505472A1 (en) * | 2002-11-11 | 2004-05-27 | Affymetrix, Inc. | Methods for identifying dna copy number changes |
| DE602004030367D1 (de) | 2003-08-08 | 2011-01-13 | Interleukin Genetics Inc | Diagnostikum für osteoporose |
| AU2005216298B2 (en) | 2004-02-26 | 2010-09-02 | Baylor Research Institute | Compositions and methods for the systemic treatment of arthritis |
| US7309589B2 (en) | 2004-08-20 | 2007-12-18 | Vironix Llc | Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing |
| RU2271827C1 (ru) * | 2004-09-28 | 2006-03-20 | Федеральное государственное учреждение"Санкт-Петербургский научно-исследовательский институт уха, горла, носа и речи Федерального агенства по здравоохранению и социальному развитию"(ФГУ "СПбНИИ ЛОР Росздрава") | Способ определения тактики лечения рекомбинантным цитокином, регулирующим воспаление |
| WO2006097388A2 (en) * | 2005-02-08 | 2006-09-21 | Innogenetics N.V. | Nucleic acid variants in the c1qr1 gene associated with altered innate immunity. |
| US20060269946A1 (en) * | 2005-05-10 | 2006-11-30 | Young Robert P | Methods and compositions for assessment of pulmonary function and disorders |
| KR20080011292A (ko) * | 2005-05-19 | 2008-02-01 | 시너젠즈 바이오사이언스 리미티드 | 유전자 다형 분석을 사용하여 폐암 발생 위험을 평가하는방법 |
| JP2008545389A (ja) * | 2005-05-19 | 2008-12-18 | シナージェンズ バイオサイエンス リミティド | 肺機能及び肺障害の評価のための方法及び組成物 |
| EP1888779A4 (en) * | 2005-05-20 | 2009-06-10 | Synergenz Bioscience Ltd | METHOD FOR THE ANALYSIS OF POLYMORPHISMS AND USES THEREOF |
| US8263137B2 (en) * | 2005-08-04 | 2012-09-11 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US8202546B2 (en) * | 2005-08-04 | 2012-06-19 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| US7998500B2 (en) * | 2005-08-04 | 2011-08-16 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for women |
| US7901710B2 (en) * | 2005-08-04 | 2011-03-08 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| WO2007023148A2 (en) * | 2005-08-22 | 2007-03-01 | Innogenetics N.V. | Nucleic acid variants in the lbp gene associated with altered innate immunity |
| US20090220953A1 (en) * | 2005-08-24 | 2009-09-03 | C.Y.O'connor Erade Village Foundation | Identification of ancestral haplotypes and uses thereof |
| US8105775B2 (en) | 2005-10-25 | 2012-01-31 | Interleukin Genetics, Inc. | IL-1 gene cluster and associated inflammatory polymorphisms and haplotypes |
| US11306351B2 (en) | 2005-12-21 | 2022-04-19 | Affymetrix, Inc. | Methods for genotyping |
| US8338109B2 (en) | 2006-11-02 | 2012-12-25 | Mayo Foundation For Medical Education And Research | Predicting cancer outcome |
| US8101360B2 (en) * | 2006-11-15 | 2012-01-24 | Interleukin Genetics, Inc. | IL-1 gene cluster, insulin resistance and coronary artery disease associated polymorphisms and haplotypes and methods of using same |
| CN101230386B (zh) * | 2007-04-28 | 2011-09-14 | 廖凌虹 | 检测CYP2E1基因的单核苷酸多态性位点rs2480256的引物在制造用于评估系统性红斑狼疮易感性的试剂盒的用途 |
| US8200440B2 (en) | 2007-05-18 | 2012-06-12 | Affymetrix, Inc. | System, method, and computer software product for genotype determination using probe array data |
| US20080293589A1 (en) * | 2007-05-24 | 2008-11-27 | Affymetrix, Inc. | Multiplex locus specific amplification |
| JP5762282B2 (ja) * | 2008-05-02 | 2015-08-12 | インタールーキン ジェネティクス, インコーポレイテッド | 変形性関節症に関連する状態に対する遺伝的素因の検出 |
| EP2806054A1 (en) | 2008-05-28 | 2014-11-26 | Genomedx Biosciences Inc. | Systems and methods for expression-based discrimination of distinct clinical disease states in prostate cancer |
| US10407731B2 (en) | 2008-05-30 | 2019-09-10 | Mayo Foundation For Medical Education And Research | Biomarker panels for predicting prostate cancer outcomes |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9074258B2 (en) | 2009-03-04 | 2015-07-07 | Genomedx Biosciences Inc. | Compositions and methods for classifying thyroid nodule disease |
| CN102459596B (zh) * | 2009-05-06 | 2016-09-07 | 库尔纳公司 | 通过针对脂质转运和代谢基因的天然反义转录物的抑制治疗脂质转运和代谢基因相关疾病 |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| US10446272B2 (en) | 2009-12-09 | 2019-10-15 | Veracyte, Inc. | Methods and compositions for classification of samples |
| WO2011104027A1 (en) * | 2010-02-26 | 2011-09-01 | Qiagen Gmbh | Process for parallel isolation and/or purification of rna and dna |
| US20130267443A1 (en) | 2010-11-19 | 2013-10-10 | The Regents Of The University Of Michigan | ncRNA AND USES THEREOF |
| CN103547680B (zh) | 2010-12-09 | 2017-05-24 | 白细胞介素遗传学公司 | 用于确定牙周病的严重性和进展的改进方法和试剂盒 |
| EP2791359B1 (en) | 2011-12-13 | 2020-01-15 | Decipher Biosciences, Inc. | Cancer diagnostics using non-coding transcripts |
| DK3435084T3 (da) | 2012-08-16 | 2023-05-30 | Mayo Found Medical Education & Res | Prostatakræftprognose under anvendelse af biomarkører |
| EP3626308A1 (en) | 2013-03-14 | 2020-03-25 | Veracyte, Inc. | Methods for evaluating copd status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| CN103397022A (zh) * | 2013-07-17 | 2013-11-20 | 上海交通大学医学院附属瑞金医院 | 与Graves病或Graves眼病相关的核苷酸多态性标记及其应用 |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3215170A4 (en) | 2014-11-05 | 2018-04-25 | Veracyte, Inc. | Systems and methods of diagnosing idiopathic pulmonary fibrosis on transbronchial biopsies using machine learning and high dimensional transcriptional data |
| CA3011363A1 (en) | 2016-01-12 | 2017-07-20 | Interleukin Genetics, Inc. | Methods for predicting response to treatment |
| EP3504348B1 (en) | 2016-08-24 | 2022-12-14 | Decipher Biosciences, Inc. | Use of genomic signatures to predict responsiveness of patients with prostate cancer to post-operative radiation therapy |
| US10329620B2 (en) | 2017-01-12 | 2019-06-25 | Cardioforecast Ltd. | Methods and kits for treating cardiovascular disease |
| EP3571322B9 (en) | 2017-01-20 | 2023-10-04 | VERACYTE SD, Inc. | Molecular subtyping, prognosis, and treatment of bladder cancer |
| EP3593140A4 (en) | 2017-03-09 | 2021-01-06 | Decipher Biosciences, Inc. | SUBTYPING PROSTATE CANCER TO PREDICT RESPONSE TO HORMONE THERAPY |
| CA3062716A1 (en) | 2017-05-12 | 2018-11-15 | Decipher Biosciences, Inc. | Genetic signatures to predict prostate cancer metastasis and identify tumor agressiveness |
| US11217329B1 (en) | 2017-06-23 | 2022-01-04 | Veracyte, Inc. | Methods and systems for determining biological sample integrity |
| WO2019028285A2 (en) | 2017-08-04 | 2019-02-07 | Genomedx, Inc. | USE OF SPECIFIC GENE EXPRESSION OF IMMUNE CELLS FOR THE PROGNOSIS OF PROSTATE CANCER AND THE PREDICTION OF SENSITIVITY TO RADIOTHERAPY |
| DE102018104133B4 (de) * | 2018-02-23 | 2025-02-20 | Klinikum der Universität München, Anstalt des öffentlichen Rechts | Biomarker zur Feststellung einer möglichen Unverträglichkeit gegenüber Metallimplantaten |
| WO2019200213A1 (en) * | 2018-04-12 | 2019-10-17 | Mayo Foundation For Medical Education And Research | Methods for guiding therapy decisions in seizure disorders |
| CN109295211A (zh) * | 2018-10-30 | 2019-02-01 | 深圳市万众基因转化医学研究院 | 一种人类斑秃相关基因突变筛查的组合引物及其应用 |
| EP3911369A4 (en) | 2019-01-18 | 2022-11-16 | Orthobio Therapeutics, Inc. | EDITING GENES TO IMPROVE JOINT FUNCTION |
| WO2020215051A1 (en) * | 2019-04-19 | 2020-10-22 | Rpi Consulting Llc | Treatments for pregnancy-related conditions |
| US20220249660A1 (en) | 2019-06-06 | 2022-08-11 | Sitokine Limited | Compositions and methods for treating lung, colorectal and breast cancer |
| WO2021028469A1 (en) | 2019-08-12 | 2021-02-18 | Sitokine Limited | Compositions and methods for treating cytokine release syndrome and neurotoxicity |
| WO2021205013A1 (en) | 2020-04-09 | 2021-10-14 | Sitokine Limited | Compositions and methods for treating covid-19 |
| IL299846A (en) * | 2020-07-16 | 2023-03-01 | Orthobio Therapeutics Inc | Gene editing to improve joint function |
| US20240327914A1 (en) * | 2021-07-08 | 2024-10-03 | Martin Levine | Devices, kits, and methods for determining increased susceptibility to and treatment and prevention of periodontitis, alzheimer’s disease, and other conditions |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3587605T2 (de) * | 1984-12-25 | 1994-03-17 | Dainippon Pharmaceutical Co | Interleukin-1 und dessen Derivat. |
| US5582979A (en) * | 1989-04-21 | 1996-12-10 | Marshfield Clinic | Length polymorphisms in (dC-dA)n.(dG-dT)n sequences and method of using the same |
| US5780587A (en) * | 1990-08-24 | 1998-07-14 | President And Fellows Of Harvard College | Compounds and methods for inhibiting β-protein filament formation and neurotoxicity |
| US5681940A (en) * | 1994-11-02 | 1997-10-28 | Icn Pharmaceuticals | Sugar modified nucleosides and oligonucleotides |
| US5993817A (en) * | 1995-01-23 | 1999-11-30 | Xenotech | Method to ameliorate osteolysis and metastasis |
| US5686246A (en) | 1995-08-03 | 1997-11-11 | Kornman; Kenneth S. | Detecting genetic predisposition to periodontal disease |
| US5942390A (en) | 1996-01-12 | 1999-08-24 | Cedars-Sinai Medical Center | Method of diagnosing predisposition for ulcerative colitis in Jewish population by detection of interleukin-1 receptor antagonist polymorphism |
| US5698399A (en) * | 1996-04-05 | 1997-12-16 | Duff; Gordon W. | Detecting genetic predisposition for osteoporosis |
| GB9610281D0 (en) * | 1996-05-16 | 1996-07-24 | Ralston Stuart H | Diagnostic method and apparatus |
| GB9621129D0 (en) | 1996-10-10 | 1996-11-27 | Duff Gordon W | Detecting genetic predisposition to sight-threatening diabetic retinopathy |
| US6210877B1 (en) * | 1997-03-10 | 2001-04-03 | Interleukin Genetics, Inc. | Prediction of coronary artery disease |
| GB9706359D0 (en) | 1997-03-27 | 1997-05-14 | Gemini International Holdings | Polymorphisms of an il-1 receptor antagonist gene |
| GB9711040D0 (en) * | 1997-05-29 | 1997-07-23 | Duff Gordon W | Prediction of inflammatory disease |
| GB9723553D0 (en) * | 1997-11-07 | 1998-01-07 | Duff Gordon W | Prediction of the risk of chronic obstructive airway disease |
| US6746839B1 (en) * | 1998-01-12 | 2004-06-08 | Interleukin Genetics, Inc. | Diagnostics and therapeutics for an obstructive airway disease |
| US6733967B1 (en) * | 1998-04-21 | 2004-05-11 | Interleukin Genetics, Inc. | Fetal testing for prediction of low birth weight |
| US6251598B1 (en) * | 1998-10-30 | 2001-06-26 | Interleukin Genetics, Inc. | Methods for diagnosing sepsis |
| AU2002320100A1 (en) * | 2001-06-15 | 2003-01-02 | Interleukin Genetics, Inc. | Methods for detecting and treating the early onset of aging-related conditions |
| CN1753903B (zh) * | 2001-11-19 | 2010-05-12 | 白介素遗传公司 | 影响转录和对炎性和传染性疾病的敏感性的白细胞介素-1基因座的功能多态性 |
-
1997
- 1997-05-29 GB GBGB9711040.7A patent/GB9711040D0/en active Pending
-
1998
- 1998-05-21 EA EA199901097A patent/EA199901097A1/ru unknown
- 1998-05-21 EP EP98922938A patent/EP0983385B1/en not_active Expired - Lifetime
- 1998-05-21 AU AU75398/98A patent/AU755107B2/en not_active Ceased
- 1998-05-21 CN CNB98807656XA patent/CN1177059C/zh not_active Expired - Lifetime
- 1998-05-21 ES ES98922938T patent/ES2342992T3/es not_active Expired - Lifetime
- 1998-05-21 PL PL98337080A patent/PL337080A1/xx unknown
- 1998-05-21 DE DE69841588T patent/DE69841588D1/de not_active Expired - Lifetime
- 1998-05-21 CA CA002291731A patent/CA2291731A1/en not_active Abandoned
- 1998-05-21 JP JP50035899A patent/JP2002500513A/ja active Pending
- 1998-05-21 AT AT98922938T patent/ATE462800T1/de not_active IP Right Cessation
- 1998-05-21 IL IL13312898A patent/IL133128A0/xx unknown
- 1998-05-21 BR BR9809183-2A patent/BR9809183A/pt not_active Application Discontinuation
- 1998-05-21 WO PCT/GB1998/001481 patent/WO1998054359A1/en not_active Ceased
- 1998-05-26 ZA ZA984490A patent/ZA984490B/xx unknown
- 1998-05-28 AR ARP980102477A patent/AR016754A1/es unknown
- 1998-05-29 TW TW087108415A patent/TWI236502B/zh not_active IP Right Cessation
-
1999
- 1999-06-30 US US09/345,217 patent/US6268142B1/en not_active Expired - Lifetime
- 1999-11-26 NO NO995803A patent/NO995803L/no not_active Application Discontinuation
-
2001
- 2001-04-27 US US09/845,129 patent/US6706478B2/en not_active Expired - Lifetime
-
2004
- 2004-03-15 US US10/802,061 patent/US20040152124A1/en not_active Abandoned
-
2007
- 2007-10-02 US US11/866,073 patent/US20080187920A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69841588D1 (de) | 2010-05-12 |
| ES2342992T3 (es) | 2010-07-20 |
| ZA984490B (en) | 1998-12-02 |
| CN1177059C (zh) | 2004-11-24 |
| AU7539898A (en) | 1998-12-30 |
| CA2291731A1 (en) | 1998-12-03 |
| GB9711040D0 (en) | 1997-07-23 |
| AU755107B2 (en) | 2002-12-05 |
| US6706478B2 (en) | 2004-03-16 |
| IL133128A0 (en) | 2001-03-19 |
| EP0983385B1 (en) | 2010-03-31 |
| JP2002500513A (ja) | 2002-01-08 |
| NO995803D0 (no) | 1999-11-26 |
| US6268142B1 (en) | 2001-07-31 |
| US20080187920A1 (en) | 2008-08-07 |
| EA199901097A1 (ru) | 2000-06-26 |
| PL337080A1 (en) | 2000-07-31 |
| US20040152124A1 (en) | 2004-08-05 |
| EP0983385A1 (en) | 2000-03-08 |
| BR9809183A (pt) | 2000-08-01 |
| US20020146700A1 (en) | 2002-10-10 |
| WO1998054359A1 (en) | 1998-12-03 |
| TWI236502B (en) | 2005-07-21 |
| CN1278868A (zh) | 2001-01-03 |
| AR016754A1 (es) | 2001-08-01 |
| NO995803L (no) | 2000-01-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE462800T1 (de) | Vorhersage von entzündlichen krankeiten assoziert mit il-1 genlocus polymorphismen | |
| PT966447E (pt) | Moleculas pequenas uteis no tratamento de doencas inflamatorias | |
| DE59809758D1 (de) | Lichtschutzmittel | |
| EP0783203A4 (en) | BRIDGE POWER CONVERTER | |
| DE59813010D1 (de) | Homopolymere mit hoher photoinduzierbarer doppelbrechung | |
| NO983112L (no) | Lysbeskyttelsesmidler | |
| FI980679L (fi) | Kannatinpalkki | |
| IT1303761B1 (it) | Filatoio con gruppi di sezioni | |
| AU2003200791A1 (en) | Prediction of inflammatory disease associated with IL-1 geneloci polymorphisms | |
| KR970013847U (ko) | 조립식 중앙분리대의 구조 | |
| KR960001863U (ko) | 조립식 중앙분리대 | |
| KR950027646U (ko) | 분해 조립식 부잔교 | |
| KR970026584U (ko) | 냉면기 | |
| NO20002881L (no) | Flytende produksjonsinstallasjon | |
| KR970038942U (ko) | 리프트의 구조 | |
| KR960037400U (ko) | 건축시공용 리프트 | |
| ATA56095A (de) | Bauaufzug | |
| KR970044256U (ko) | 전자렌지 다리설치구조 | |
| SE9703610D0 (sv) | Production of microcuvettes | |
| KR950028092U (ko) | 온돌판의 조립구조 | |
| KR960019853U (ko) | 조립식 설합장의 구조 | |
| BR7402226U (pt) | Escada pré-fabricada | |
| IT1294703B1 (it) | Struttura di acquario o acquaterrario | |
| IT1294121B1 (it) | Lavastoviglie con mezzi di circolazione dell'acqua | |
| KR960021589U (ko) | 자동차 전조등의 구조 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |