ATE461935T1 - Verfahren zur reinigung von stark anionischen proteinen - Google Patents

Verfahren zur reinigung von stark anionischen proteinen

Info

Publication number
ATE461935T1
ATE461935T1 AT06006739T AT06006739T ATE461935T1 AT E461935 T1 ATE461935 T1 AT E461935T1 AT 06006739 T AT06006739 T AT 06006739T AT 06006739 T AT06006739 T AT 06006739T AT E461935 T1 ATE461935 T1 AT E461935T1
Authority
AT
Austria
Prior art keywords
purifying
proteins
sulfations
sulfated
anionic proteins
Prior art date
Application number
AT06006739T
Other languages
English (en)
Inventor
Jonathan L Coffman
William Barry Foster
Bonnie J Germain
Shujun Sun
Jeffrey J Robinson
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Application granted granted Critical
Publication of ATE461935T1 publication Critical patent/ATE461935T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
AT06006739T 2000-03-27 2001-03-27 Verfahren zur reinigung von stark anionischen proteinen ATE461935T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19335100P 2000-03-27 2000-03-27

Publications (1)

Publication Number Publication Date
ATE461935T1 true ATE461935T1 (de) 2010-04-15

Family

ID=22713294

Family Applications (3)

Application Number Title Priority Date Filing Date
AT01922750T ATE328895T1 (de) 2000-03-27 2001-03-27 Methoden zur reinigung von stark anionischen proteinen
AT06006740T ATE448241T1 (de) 2000-03-27 2001-03-27 Verfahren zur reinigung stark anionischer proteine
AT06006739T ATE461935T1 (de) 2000-03-27 2001-03-27 Verfahren zur reinigung von stark anionischen proteinen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT01922750T ATE328895T1 (de) 2000-03-27 2001-03-27 Methoden zur reinigung von stark anionischen proteinen
AT06006740T ATE448241T1 (de) 2000-03-27 2001-03-27 Verfahren zur reinigung stark anionischer proteine

Country Status (11)

Country Link
US (1) US6933370B2 (de)
EP (3) EP1681299B1 (de)
JP (2) JP5025874B2 (de)
AT (3) ATE328895T1 (de)
AU (2) AU4951501A (de)
CA (1) CA2404155C (de)
DE (3) DE60120374T2 (de)
DK (3) DK1681299T3 (de)
ES (3) ES2338687T3 (de)
NZ (1) NZ521578A (de)
WO (1) WO2001072769A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7223848B2 (en) 2001-06-05 2007-05-29 Genetics Institute, Llc Methods for purifying Fc-containing proteins
CA2483476A1 (en) * 2002-04-22 2003-10-30 Absorber, Ab Fusion polypeptides and methods for inhibiting microbial adhesion
US7427659B2 (en) 2003-10-24 2008-09-23 Amgen Inc. Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
BRPI0612672B8 (pt) * 2005-06-24 2021-05-25 Cerule Llc composição de extrato aquoso de alga verde-azulada
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
PT1969007E (pt) * 2005-12-20 2013-12-10 Bristol Myers Squibb Co Composições e métodos para a produção de uma composição
US8853371B2 (en) 2006-10-19 2014-10-07 Janssen Biotech, Inc. Process for preparing unaggregated antibody Fc domains
WO2011090720A2 (en) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd Purification of proteins
WO2011098526A1 (en) * 2010-02-12 2011-08-18 Dsm Ip Assets B.V. Single unit antibody purification
EP2619217B1 (de) * 2010-09-20 2016-11-09 Bio-Rad Laboratories, Inc. Dissoziation von produktkomplex-kontaminantien in der chromatographie
BR112019007856A8 (pt) * 2016-10-28 2023-04-11 Merck Sharp & Dohme Composição, e, método para remover anticorpos de tirosina sulfatada ou fragmentos de ligação a antígeno dos mesmos
JP7065105B2 (ja) * 2017-02-09 2022-05-11 ブラッコ・スイス・ソシエテ・アノニム 可溶性ｐｓｇｌ－１タンパク質変異体の精製のための方法
US11447547B1 (en) 2017-12-13 2022-09-20 Amgen Inc. Method of antigen-binding protein production

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
US5115101A (en) 1988-06-08 1992-05-19 Miles Inc. Removal of protein A from antibody preparations
US5378464A (en) * 1989-03-08 1995-01-03 Board Of Regents Of The University Of Oklahoma Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5464778A (en) 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
DE69333346T2 (de) * 1992-10-23 2004-10-07 Inst Genetics Llc Neuartiges p- selectin ligandenprotein
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
US5843707A (en) * 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
DE69522492T2 (de) 1994-04-09 2002-05-23 Hoffmann La Roche Verfahren zur Herstellung von Alpha-Interferon
US6008328A (en) 1994-10-13 1999-12-28 Amgen Inc. Method for purifying keratinocyte growth factors
SE503424C2 (sv) 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
FR2738009B1 (fr) 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
HU222666B1 (hu) 1996-11-15 2003-09-29 Genentech, Inc. Eljárás neuorotrofinok tisztítására
AU9695698A (en) * 1997-10-14 1999-05-03 Avant Immunotherapeutics, Inc. Method for purifying retroviral particles and soluble viral antigens

Also Published As

Publication number Publication date
ES2266188T3 (es) 2007-03-01
EP1681299B1 (de) 2009-11-11
ES2343023T3 (es) 2010-07-21
DE60120374D1 (de) 2006-07-20
US6933370B2 (en) 2005-08-23
AU2001249515B2 (en) 2006-10-05
EP1681299A2 (de) 2006-07-19
CA2404155A1 (en) 2001-10-04
DE60141657D1 (de) 2010-05-06
JP2003528884A (ja) 2003-09-30
ES2338687T3 (es) 2010-05-11
EP1681298B1 (de) 2010-03-24
EP1681299A3 (de) 2006-12-27
WO2001072769A2 (en) 2001-10-04
DE60140493D1 (de) 2009-12-24
CA2404155C (en) 2011-08-09
EP1681298A3 (de) 2006-12-20
JP2012184245A (ja) 2012-09-27
ATE448241T1 (de) 2009-11-15
DE60120374T2 (de) 2007-06-06
AU4951501A (en) 2001-10-08
WO2001072769A3 (en) 2002-02-07
US20020132991A1 (en) 2002-09-19
DK1681299T3 (da) 2010-02-01
DK1268514T3 (da) 2006-10-09
ATE328895T1 (de) 2006-06-15
EP1268514B1 (de) 2006-06-07
NZ521578A (en) 2004-08-27
EP1681298A2 (de) 2006-07-19
WO2001072769A9 (en) 2003-04-03
EP1268514A2 (de) 2003-01-02
JP5596078B2 (ja) 2014-09-24
DK1681298T3 (da) 2010-06-14
JP5025874B2 (ja) 2012-09-12

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Legal Events

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