ATE445839T1 - Latentes tuberkulose-diagnostisches antigen und verwendungsmethode - Google Patents
Latentes tuberkulose-diagnostisches antigen und verwendungsmethodeInfo
- Publication number
- ATE445839T1 ATE445839T1 AT02704064T AT02704064T ATE445839T1 AT E445839 T1 ATE445839 T1 AT E445839T1 AT 02704064 T AT02704064 T AT 02704064T AT 02704064 T AT02704064 T AT 02704064T AT E445839 T1 ATE445839 T1 AT E445839T1
- Authority
- AT
- Austria
- Prior art keywords
- latent tuberculosis
- methods
- diagnostic antigen
- tuberculosis diagnostic
- subject
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 5
- 206010065048 Latent tuberculosis Diseases 0.000 title abstract 3
- 239000000427 antigen Substances 0.000 title abstract 2
- 102000036639 antigens Human genes 0.000 title abstract 2
- 108091007433 antigens Proteins 0.000 title abstract 2
- 230000028993 immune response Effects 0.000 abstract 2
- 206010018691 Granuloma Diseases 0.000 abstract 1
- 102000007362 alpha-Crystallins Human genes 0.000 abstract 1
- 108010007908 alpha-Crystallins Proteins 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 208000033353 latent tuberculosis infection Diseases 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/5695—Mycobacteria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A61P31/06—Antibacterial agents for tuberculosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/025—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
- G01N33/56955—Bacteria involved in periodontal diseases
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US26034801P | 2001-01-08 | 2001-01-08 | |
| US31123501P | 2001-08-09 | 2001-08-09 | |
| PCT/US2002/000309 WO2002054073A2 (en) | 2001-01-08 | 2002-01-07 | Latent human tuberculosis model, diagnostic antigens, and methods of use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE445839T1 true ATE445839T1 (de) | 2009-10-15 |
Family
ID=26947939
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02704064T ATE445839T1 (de) | 2001-01-08 | 2002-01-07 | Latentes tuberkulose-diagnostisches antigen und verwendungsmethode |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7105170B2 (de) |
| EP (1) | EP1360498B1 (de) |
| JP (1) | JP3944452B2 (de) |
| AT (1) | ATE445839T1 (de) |
| AU (1) | AU2002237764B2 (de) |
| CA (2) | CA2689741C (de) |
| DE (1) | DE60234015D1 (de) |
| WO (1) | WO2002054073A2 (de) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1523331B1 (de) * | 2002-07-13 | 2013-02-27 | Statens Serum Institut | Therapeutisches vakzin gegen tuberkulosis |
| ES2231037B1 (es) * | 2003-10-31 | 2005-12-16 | Archivel Technologies, Sl | Agente inmunoterapico util para el tratamiento combinado de la tuberculosis en asociacion con otros farmacos. |
| FR2872579B1 (fr) * | 2004-06-30 | 2006-11-24 | Pasteur Institut | Detection de la tuberculose et de l'infection par mycobacterium tuberculosis a l'aide de hbha |
| NZ562142A (en) * | 2005-03-31 | 2009-12-24 | Univ Leiden Medical Ct | Methods and means for diagnostics, prevention and treatment of Mycobacterium infections and tuberculosis disease |
| JP2009528545A (ja) * | 2006-03-02 | 2009-08-06 | ザ ユーエービー リサーチ ファウンデーション | マイコバクテリウム属の疾患検出、処置、および薬物開発 |
| EP2152853A4 (de) * | 2007-04-30 | 2010-06-16 | Univ Central Florida Res Found | In-vitro-modell einer latenten mykobakterieninfektion |
| US8058022B2 (en) | 2009-07-27 | 2011-11-15 | Indian Institute Of Science | Diagnosis and monitoring of mycobacterium tuberculosis infection |
| EP2807487B1 (de) * | 2012-01-27 | 2017-11-29 | PEAS Institut AB | Verfahren zum nachweis von tuberkulose |
| US10564150B2 (en) * | 2012-12-28 | 2020-02-18 | Cellestis Limited | Cell mediated immune response assay |
| KR101552610B1 (ko) | 2013-09-24 | 2015-09-18 | 연세대학교 산학협력단 | 육아종 동물모델 및 그 제조방법 |
| EP3169793B1 (de) | 2014-07-16 | 2022-07-06 | Tangen Biosciences Inc. | Isothermische verfahren zur amplifizierung von nukleinsäureproben |
| WO2016073353A1 (en) | 2014-11-03 | 2016-05-12 | Tangen Biosciences, Inc. | Apparatus and method for cell, spore, or virus capture and disruption |
| CN109030825A (zh) * | 2017-06-12 | 2018-12-18 | 广东体必康生物科技有限公司 | 用于特异性检测结核分枝杆菌感染的蛋白Rv2031c |
| RU2702609C1 (ru) * | 2018-08-06 | 2019-10-08 | Федеральное государственное бюджетное учреждение "Новосибирский научно-исследовательский институт туберкулеза" Министерства здравоохранения Российской Федерации (ФГБУ "ННИИТ" Минздрава России) | Способ моделирования туберкулезной инфекции in vitro |
| US20220361461A1 (en) * | 2019-06-28 | 2022-11-17 | United States Government As Represented By The Department Of Veterans Affairs | Methods of producing granulomas and animal models of sarcoidosis |
| CN115598041B (zh) * | 2021-07-07 | 2025-08-19 | 中国科学院微生物研究所 | 结核鉴别诊断细胞因子及其在结核感染风险评估中的应用 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1750197A (en) * | 1996-01-17 | 1997-08-11 | Trustees Of Boston University | Mycobacterium antigens and methods for their detection |
| US5824546A (en) | 1996-03-27 | 1998-10-20 | The Johns Hopkins University | Regulation of a sigma factor from Mycobacterium tuberculosis |
| US5700925A (en) | 1996-03-27 | 1997-12-23 | The Johns Hopkins University | DNA encoding stationary phase, stress response sigma factor from Mycobacterium tuberculosis |
| AU732858B2 (en) * | 1996-03-27 | 2001-05-03 | Johns Hopkins University, The | Stationary phase, stress response sigma factor from mycobacterium tuberculosis, and regulation thereof |
| CA2276491C (en) | 1996-12-31 | 2008-01-22 | New York University | Early detection of mycobacterial disease |
| EP0994944A1 (de) * | 1997-07-10 | 2000-04-26 | THE GOVERNMENT OF THE UNITED STATES OF AMERICA as represented by the SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | Haarschneideverfahren un - vorrichtung |
| NZ504951A (en) * | 1997-11-10 | 2001-06-29 | Statens Seruminstitut | Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis |
-
2002
- 2002-01-07 WO PCT/US2002/000309 patent/WO2002054073A2/en not_active Ceased
- 2002-01-07 AT AT02704064T patent/ATE445839T1/de not_active IP Right Cessation
- 2002-01-07 CA CA2689741A patent/CA2689741C/en not_active Expired - Lifetime
- 2002-01-07 DE DE60234015T patent/DE60234015D1/de not_active Expired - Lifetime
- 2002-01-07 EP EP02704064A patent/EP1360498B1/de not_active Expired - Lifetime
- 2002-01-07 CA CA2433069A patent/CA2433069C/en not_active Expired - Lifetime
- 2002-01-07 JP JP2002554720A patent/JP3944452B2/ja not_active Expired - Lifetime
- 2002-01-07 AU AU2002237764A patent/AU2002237764B2/en not_active Expired
- 2002-01-07 US US10/250,930 patent/US7105170B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE60234015D1 (de) | 2009-11-26 |
| CA2433069C (en) | 2010-03-30 |
| JP2005506512A (ja) | 2005-03-03 |
| US20040146933A1 (en) | 2004-07-29 |
| AU2002237764B2 (en) | 2007-08-23 |
| CA2689741C (en) | 2013-10-01 |
| EP1360498B1 (de) | 2009-10-14 |
| JP3944452B2 (ja) | 2007-07-11 |
| CA2689741A1 (en) | 2002-07-11 |
| WO2002054073A2 (en) | 2002-07-11 |
| CA2433069A1 (en) | 2002-07-11 |
| US7105170B2 (en) | 2006-09-12 |
| WO2002054073A3 (en) | 2003-08-28 |
| EP1360498A2 (de) | 2003-11-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |