ATE445015T1 - Verfahren zur herstellung rekombinanter, lipid- modifizierter psaa proteine und deren verwendung - Google Patents

Verfahren zur herstellung rekombinanter, lipid- modifizierter psaa proteine und deren verwendung

Info

Publication number
ATE445015T1
ATE445015T1 AT99903011T AT99903011T ATE445015T1 AT E445015 T1 ATE445015 T1 AT E445015T1 AT 99903011 T AT99903011 T AT 99903011T AT 99903011 T AT99903011 T AT 99903011T AT E445015 T1 ATE445015 T1 AT E445015T1
Authority
AT
Austria
Prior art keywords
proteins
psaa
psaa proteins
lipidated psaa
lipid
Prior art date
Application number
AT99903011T
Other languages
English (en)
Inventor
Edwin Ades
George Carlone
Barun De
Jacquelyn Sampson
Robert Huebner
Original Assignee
Ct Disease Contr & Prevention
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ct Disease Contr & Prevention filed Critical Ct Disease Contr & Prevention
Application granted granted Critical
Publication of ATE445015T1 publication Critical patent/ATE445015T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT99903011T 1998-02-03 1999-01-14 Verfahren zur herstellung rekombinanter, lipid- modifizierter psaa proteine und deren verwendung ATE445015T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1778298A 1998-02-03 1998-02-03
PCT/US1999/000379 WO1999040200A1 (en) 1998-02-03 1999-01-14 RECOMBINANT LIPIDATED PsaA PROTEIN, METHODS OF PREPARATION AND USE

Publications (1)

Publication Number Publication Date
ATE445015T1 true ATE445015T1 (de) 2009-10-15

Family

ID=21784518

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99903011T ATE445015T1 (de) 1998-02-03 1999-01-14 Verfahren zur herstellung rekombinanter, lipid- modifizierter psaa proteine und deren verwendung

Country Status (13)

Country Link
US (2) US7635486B1 (de)
EP (1) EP1053329B1 (de)
JP (1) JP4290875B2 (de)
AT (1) ATE445015T1 (de)
AU (1) AU2313199A (de)
BR (1) BR9909097A (de)
CA (1) CA2319404C (de)
DE (1) DE69941505D1 (de)
DK (1) DK1053329T3 (de)
ES (1) ES2334185T3 (de)
NZ (1) NZ525674A (de)
PT (1) PT1053329E (de)
WO (1) WO1999040200A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6903184B1 (en) 1998-03-02 2005-06-07 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Multiple antigenic peptides immunogenic against Streptococcus pneumonia
PT1790660E (pt) * 2000-02-28 2012-09-17 Novartis Vaccines & Diagnostic Expressão heteróloga de proteínas de neisseria
AU7193501A (en) * 2000-07-10 2002-01-21 Us Health Multiple antigenic peptides immunogenic against streptococcus pneumoniae
MX339524B (es) 2001-10-11 2016-05-30 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica.
MXPA05011110A (es) * 2003-04-16 2006-01-24 Wyeth Corp Composiciones inmunogenicas novedosas para la prevencion y tratamiento de un padecimiento originado por meningococos.
AR064642A1 (es) 2006-12-22 2009-04-15 Wyeth Corp Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi
PL3246044T5 (pl) 2010-08-23 2024-06-17 Wyeth Llc Stabilne preparaty antygenów rLP2086 Neisseria meningitidis
PE20140173A1 (es) 2010-09-10 2014-02-20 Wyeth Llc Variantes no lipidadas de antigenos orf2086 de neisseria meningitidis
SA115360586B1 (ar) 2012-03-09 2017-04-12 فايزر انك تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها
EP4043029A1 (de) 2012-03-09 2022-08-17 Pfizer Inc. Neisseria meningitidis-zusammensetzungen und verfahren dafür
US9802987B2 (en) 2013-03-08 2017-10-31 Pfizer Inc. Immunogenic fusion polypeptides
EP3041502A2 (de) 2013-09-08 2016-07-13 Pfizer Inc. Neisseria meningitidis-zusammensetzungen und verfahren dafür
CN103773779B (zh) * 2013-12-31 2017-02-15 李越希 化学合成肺炎链球菌表面粘附素a的基因片段及表达、应用
US10888611B2 (en) 2015-02-19 2021-01-12 Pfizer Inc. Neisseria meningitidis compositions and methods thereof
CN108884134A (zh) * 2015-12-10 2018-11-23 加拿大全国研究委员会 脂化肺炎链球菌抗原组合物、制备方法和用途
JP7010961B2 (ja) 2017-01-31 2022-02-10 ファイザー・インク 髄膜炎菌組成物およびその方法
KR102871663B1 (ko) 2019-09-27 2025-10-16 화이자 인코포레이티드 네이세리아 메닌기티디스 조성물 및 그의 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993010238A1 (en) 1991-11-14 1993-05-27 The Government Of The United States Of America As Represented By The Department Of Health And Human Services Pneumococcal fimbrial protein a vaccines
ES2271954T3 (es) 1995-06-07 2007-04-16 Sanofi Pasteur Inc. Expresion de lipoproteinas.
US6924112B1 (en) * 1997-12-04 2005-08-02 Biomethodes S.A.R.L. Cloning method by multiple-digestion, vectors for implementing same and applications
NO983911D0 (no) * 1998-08-26 1998-08-26 Norsk Hydro As Alginatkapsler til bruk ved behandling av hjernesvulst

Also Published As

Publication number Publication date
US7635486B1 (en) 2009-12-22
JP4290875B2 (ja) 2009-07-08
DE69941505D1 (de) 2009-11-19
EP1053329A1 (de) 2000-11-22
US20100260802A1 (en) 2010-10-14
NZ525674A (en) 2005-01-28
EP1053329B1 (de) 2009-10-07
PT1053329E (pt) 2010-01-04
DK1053329T3 (da) 2010-01-25
CA2319404A1 (en) 1999-08-12
ES2334185T3 (es) 2010-03-05
WO1999040200A1 (en) 1999-08-12
JP2002505083A (ja) 2002-02-19
CA2319404C (en) 2014-01-07
US7960535B2 (en) 2011-06-14
BR9909097A (pt) 2000-12-05
AU2313199A (en) 1999-08-23

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