ATE444737T1 - Pharmakologisch aktive ionisierbare substanzen enthaltende neue pharmazeutische formulierungen sowie verfahren zu deren herstellung - Google Patents

Pharmakologisch aktive ionisierbare substanzen enthaltende neue pharmazeutische formulierungen sowie verfahren zu deren herstellung

Info

Publication number
ATE444737T1
ATE444737T1 AT91920634T AT91920634T ATE444737T1 AT E444737 T1 ATE444737 T1 AT E444737T1 AT 91920634 T AT91920634 T AT 91920634T AT 91920634 T AT91920634 T AT 91920634T AT E444737 T1 ATE444737 T1 AT E444737T1
Authority
AT
Austria
Prior art keywords
pharmacologically active
production
pharmaceutical formulations
substances containing
new pharmaceutical
Prior art date
Application number
AT91920634T
Other languages
English (en)
Inventor
Bengt Lindstedt
Per Johan Lundberg
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE444737T1 publication Critical patent/ATE444737T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585Ion exchange resins, e.g. polystyrene sulfonic acid resin
AT91920634T 1990-12-07 1991-12-03 Pharmakologisch aktive ionisierbare substanzen enthaltende neue pharmazeutische formulierungen sowie verfahren zu deren herstellung ATE444737T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9003903A SE9003903D0 (sv) 1990-12-07 1990-12-07 New pharmaceutical formulations
PCT/SE1991/000814 WO1992010171A1 (en) 1990-12-07 1991-12-03 New pharmaceutical formulations containing a pharmacologically active ionizable substance as well as process for the preparation thereof

Publications (1)

Publication Number Publication Date
ATE444737T1 true ATE444737T1 (de) 2009-10-15

Family

ID=20381122

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91920634T ATE444737T1 (de) 1990-12-07 1991-12-03 Pharmakologisch aktive ionisierbare substanzen enthaltende neue pharmazeutische formulierungen sowie verfahren zu deren herstellung

Country Status (17)

Country Link
US (2) US5707656A (de)
EP (1) EP0560816B1 (de)
JP (1) JP3276956B2 (de)
AT (1) ATE444737T1 (de)
AU (1) AU656346B2 (de)
CA (1) CA2097176C (de)
DE (1) DE69133623D1 (de)
EE (1) EE03105B1 (de)
FI (1) FI932553A (de)
HU (1) HU218661B (de)
IE (1) IE914136A1 (de)
IS (1) IS1749B (de)
NO (1) NO305536B1 (de)
PT (1) PT99720B (de)
SE (1) SE9003903D0 (de)
WO (1) WO1992010171A1 (de)
YU (1) YU186791A (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69738966D1 (de) * 1996-12-20 2008-10-16 Mcneil Ppc Inc Durch ionenaustauscherharze verabreichte hustenmittel
EP1204406A2 (de) * 1999-07-29 2002-05-15 Roxane Laboratories, Inc. Opioidhaltige formulierung mit verzögerter freisetzung
US20030118641A1 (en) * 2000-07-27 2003-06-26 Roxane Laboratories, Inc. Abuse-resistant sustained-release opioid formulation
CN1610551A (zh) * 2001-07-06 2005-04-27 恩德制药公司 用作止痛剂的6-羟基羟吗啡酮的肠胃外给药
WO2003020242A1 (en) * 2001-08-29 2003-03-13 Srl Technologies, Inc. Sustained release preparations
AU2003230805A1 (en) * 2002-04-05 2003-10-27 Penwest Pharmaceuticals Co. Sustained release metoprolol formulations
US7314640B2 (en) * 2003-07-11 2008-01-01 Mongkol Sriwongjanya Formulation and process for drug loaded cores
US20050265955A1 (en) * 2004-05-28 2005-12-01 Mallinckrodt Inc. Sustained release preparations
JP2006296511A (ja) * 2005-04-15 2006-11-02 Transcutaneous Technologies Inc 外用剤、外用剤の塗布方法、イオントフォレーシス装置及び経皮パッチ
JP2006346368A (ja) * 2005-06-20 2006-12-28 Transcutaneous Technologies Inc イオントフォレーシス装置及びその製造方法
JPWO2007010900A1 (ja) * 2005-07-15 2009-01-29 Tti・エルビュー株式会社 貼付位置表示機能付き経皮吸収用パッチ及びイオントフォレーシス装置
JP2007037868A (ja) * 2005-08-05 2007-02-15 Transcutaneous Technologies Inc 経皮投与装置及びその制御方法
US8386030B2 (en) * 2005-08-08 2013-02-26 Tti Ellebeau, Inc. Iontophoresis device
US20070060860A1 (en) * 2005-08-18 2007-03-15 Transcutaneous Technologies Inc. Iontophoresis device
WO2007026671A1 (ja) * 2005-08-29 2007-03-08 Transcu Ltd. センサからの情報により投与すべき薬剤の選定を行うイオントフォレーシス装置
CA2619661A1 (en) * 2005-09-16 2007-03-22 Tti Ellebeau, Inc. Catheter-type iontophoresis device
US20070071807A1 (en) * 2005-09-28 2007-03-29 Hidero Akiyama Capsule-type drug-releasing device and capsule-type drug-releasing device system
WO2007038028A1 (en) * 2005-09-28 2007-04-05 Tti Ellebeau, Inc. Iontophoresis apparatus and method to deliver active agents to biological interfaces
US20090299265A1 (en) * 2005-09-30 2009-12-03 Tti Ellebeau, Inc. Electrode Assembly for Iontophoresis Having Shape-Memory Separator and Iontophoresis Device Using the Same
BRPI0616771A2 (pt) * 2005-09-30 2011-06-28 Tti Ellebeau Inc dispositivo de iontoforese para liberar múltiplos agentes ativos para interfaces biológicas
US20090187134A1 (en) * 2005-09-30 2009-07-23 Hidero Akiyama Iontophoresis Device Controlling Amounts of a Sleep-Inducing Agent and a Stimulant to be Administered and Time at Which the Drugs are Administered
US20070197955A1 (en) * 2005-10-12 2007-08-23 Transcutaneous Technologies Inc. Mucous membrane adhesion-type iontophoresis device
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
JPWO2008087803A1 (ja) * 2007-01-16 2010-05-06 国立大学法人北海道大学 抗酸化成分を封入したイオントフォレーシス用リポソーム製剤
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
TW201026347A (en) * 2008-09-10 2010-07-16 Transcu Ltd Apparatus and method to dispense HPC-based viscous liquids into porous substrates, e. g., continuous web-based process
US9238078B2 (en) 2009-04-03 2016-01-19 Coating Place, Inc. Modified-release pharmaceutical drug composition

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4983392A (en) * 1983-11-14 1991-01-08 Bio-Mimetics, Inc. Bioadhesive compositions and methods of treatment therewith
US4692462A (en) * 1985-03-18 1987-09-08 Menley & James Laboratories, Ltd. Compositions and method of controlling transdermal penetration of topical and systemic agents
EP0199855A1 (de) * 1985-05-02 1986-11-05 Gist-Brocades N.V. Trimethoprim und ein Sulfonamid enthaltende Tabletten
JPS62223112A (ja) * 1986-03-25 1987-10-01 Rooto Seiyaku Kk 歯周病治療剤
IE62100B1 (en) * 1986-07-30 1994-12-14 Fisons Corp Coated ion exchange resins
DE3740684A1 (de) * 1987-12-01 1989-06-15 Woehr Otto Gmbh Parksystem
MC2025A1 (fr) * 1988-04-20 1990-04-25 Asta Pharma Ag Medicament contenant de l'azelastine et capable de liberer celle-ci de facon controlee
IL90245A (en) * 1988-05-11 1994-04-12 Glaxo Group Ltd Resin adsorption containing ranitidine together with synthetic resin replaces cations, its preparation and pharmaceutical preparations containing it
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition
US5149523A (en) * 1989-06-20 1992-09-22 Aktiebolaget Hassle Polystyrenesulfonate-drug complex and solid dosage forms thereof

Also Published As

Publication number Publication date
EP0560816B1 (de) 2009-10-07
JP3276956B2 (ja) 2002-04-22
FI932553A0 (fi) 1993-06-04
JPH06503311A (ja) 1994-04-14
NO305536B1 (no) 1999-06-21
IS3787A7 (is) 1992-06-08
FI932553A (fi) 1993-06-04
HUT64213A (en) 1993-12-28
SE9003903D0 (sv) 1990-12-07
CA2097176A1 (en) 1992-06-08
EE03105B1 (et) 1998-08-17
IE914136A1 (en) 1992-06-17
AU656346B2 (en) 1995-02-02
IS1749B (is) 2000-07-11
US5707656A (en) 1998-01-13
PT99720A (pt) 1992-10-30
US5709882A (en) 1998-01-20
WO1992010171A1 (en) 1992-06-25
DE69133623D1 (de) 2009-11-19
CA2097176C (en) 2002-03-26
PT99720B (pt) 2002-04-29
HU218661B (hu) 2000-10-28
EP0560816A1 (de) 1993-09-22
AU8930591A (en) 1992-07-08
YU186791A (sh) 1994-04-05
NO932053D0 (no) 1993-06-04
NO932053L (no) 1993-07-20
HU9301671D0 (en) 1993-09-28

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