ATE441725T1 - Multienzym-nachweisverfahren - Google Patents
Multienzym-nachweisverfahrenInfo
- Publication number
- ATE441725T1 ATE441725T1 AT99965243T AT99965243T ATE441725T1 AT E441725 T1 ATE441725 T1 AT E441725T1 AT 99965243 T AT99965243 T AT 99965243T AT 99965243 T AT99965243 T AT 99965243T AT E441725 T1 ATE441725 T1 AT E441725T1
- Authority
- AT
- Austria
- Prior art keywords
- enzyme
- activity
- present
- measuring
- endogenous
- Prior art date
Links
- 238000001514 detection method Methods 0.000 title abstract 3
- 102000004190 Enzymes Human genes 0.000 abstract 12
- 108090000790 Enzymes Proteins 0.000 abstract 12
- 230000015556 catabolic process Effects 0.000 abstract 2
- 238000006731 degradation reaction Methods 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000758 substrate Substances 0.000 abstract 2
- 238000001952 enzyme assay Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/66—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/916—Hydrolases (3) acting on ester bonds (3.1), e.g. phosphatases (3.1.3), phospholipases C or phospholipases D (3.1.4)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US11235998P | 1998-12-15 | 1998-12-15 | |
| PCT/US1999/029550 WO2000036098A1 (en) | 1998-12-15 | 1999-12-14 | Multiple enzyme assays |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE441725T1 true ATE441725T1 (de) | 2009-09-15 |
Family
ID=22343485
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99965243T ATE441725T1 (de) | 1998-12-15 | 1999-12-14 | Multienzym-nachweisverfahren |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6586196B1 (https=) |
| EP (1) | EP1151090B1 (https=) |
| JP (1) | JP4668418B2 (https=) |
| AT (1) | ATE441725T1 (https=) |
| AU (1) | AU781255B2 (https=) |
| CA (1) | CA2353872C (https=) |
| DE (1) | DE69941367D1 (https=) |
| WO (1) | WO2000036098A1 (https=) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1472238B1 (en) | 2002-02-01 | 2012-07-04 | Promega Corporation | Bioluminescent protease assay |
| AU2004210982B2 (en) * | 2003-02-12 | 2008-12-18 | Promega Corporation | Methods and kits for dual enzymatic assays whereby light is quenched from luminescent reactions |
| US20050026151A1 (en) * | 2003-07-17 | 2005-02-03 | Voyta John C. | Simultaneous generation of multiple chemiluminescent signals on solid supports |
| US20070254320A1 (en) * | 2003-10-20 | 2007-11-01 | Alan Olstein | Method and Kit for Detecting Listeria Spp. |
| US7553632B2 (en) | 2004-01-22 | 2009-06-30 | Promega Corporation | Luminogenic and nonluminogenic multiplex assay |
| US7416854B2 (en) * | 2004-01-22 | 2008-08-26 | Promega Corporation | Luminogenic and nonluminogenic multiplex assay |
| EP1935986B1 (en) | 2005-05-31 | 2014-04-16 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| EP2778234B1 (en) | 2005-05-31 | 2017-09-27 | Promega Corporation | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions |
| KR20080050584A (ko) * | 2005-08-19 | 2008-06-09 | 커먼웰쓰 사이언티픽 앤 인더스트리알 리서치 오거니제이션 | 아라크노캄파 루시페라아제 |
| JP2009506772A (ja) * | 2005-09-01 | 2009-02-19 | プロメガ コーポレイション | 細胞ベースの発光及び非発光プロテアソームアッセイ |
| JP2007225547A (ja) * | 2006-02-27 | 2007-09-06 | Fujifilm Corp | 標的物質の疎水部位の検出方法 |
| AU2008239654A1 (en) | 2007-04-13 | 2008-10-23 | Promega Corporation | Luminescent live and dead cell assay |
| US20110124965A1 (en) * | 2008-05-08 | 2011-05-26 | Park Jason Y | Chemiluminescence enhanced detection |
| WO2010045599A1 (en) | 2008-10-17 | 2010-04-22 | Pharmacofore, Inc. | Pharmaceutical compositions with attenuated release of phenolic opioids |
| CN102695545B (zh) | 2009-09-08 | 2016-08-17 | 特色疗法股份有限公司 | 包括酶可剪切的酮改性的阿片样物质药物前体以及其可任选的抑制剂的组合物 |
| US20110097723A1 (en) * | 2009-09-19 | 2011-04-28 | Qun Liu | Methods and reagents for analyte detection |
| US8592172B2 (en) | 2010-03-11 | 2013-11-26 | Promega Corporation | Bioluminescent assays using cyanobenzothiazole compounds |
| US20110262355A1 (en) | 2010-04-21 | 2011-10-27 | Jenkins Thomas E | Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof |
| US20130059914A1 (en) | 2010-04-21 | 2013-03-07 | Signature Therapeutics, Inc. | Compositions Comprising Enzyme-Cleavable Amphetamine Prodrugs and Inhibitors Thereof |
| CA2795222A1 (en) * | 2010-04-21 | 2011-10-27 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable opioid prodrugs and inhibitors thereof |
| WO2011133178A1 (en) | 2010-04-21 | 2011-10-27 | Pharmacofore, Inc | Compositions comprising enzyme-cleavable phenol-modified tapentadol prodrug |
| EP2560490A1 (en) * | 2010-04-21 | 2013-02-27 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable prodrugs of active agents and inhibitors thereof |
| AU2012205733B2 (en) | 2011-01-11 | 2015-10-08 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable oxycodone prodrug |
| US8497237B2 (en) | 2011-01-11 | 2013-07-30 | Signature Therapeutics, Inc. | Compositions comprising enzyme-cleavable oxycodone prodrug |
| JP6148182B2 (ja) | 2011-03-09 | 2017-06-14 | シグネーチャー セラピューティクス, インク.Signature Therapeutics, Inc. | 複素環式リンカーを有する活性薬剤プロドラッグ |
| WO2012122420A2 (en) | 2011-03-09 | 2012-09-13 | Pharmacofore, Inc. | Opioid prodrugs with heterocyclic linkers |
| US20140087362A1 (en) | 2012-03-16 | 2014-03-27 | Aladar A. Szalay | Methods for assessing effectiveness and monitoring oncolytic virus treatment |
| WO2013158265A1 (en) | 2012-04-20 | 2013-10-24 | Genelux Corporation | Imaging methods for oncolytic virus therapy |
| EP2719703A1 (en) | 2012-10-12 | 2014-04-16 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Precursor molecule for the synthesis of D-luciferin |
| JP7007862B2 (ja) * | 2017-10-31 | 2022-01-25 | アークレイ株式会社 | 化学発光試薬組成物及び化学発光試薬キット |
| IL305493A (en) | 2021-03-09 | 2023-10-01 | Ensysce Biosciences Inc | Compositions comprising enzyme-cleavable prodrugs and controlled release nafamostat and methods of use thereof |
| CA3230025A1 (en) | 2021-09-29 | 2023-04-06 | Lynn Kirkpatrick | Enzyme-cleavable methadone prodrugs and methods of use thereof |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4124388A (en) | 1977-05-02 | 1978-11-07 | Polaroid Corporation | Ammonium mordants for photographic dyes |
| US4424326A (en) | 1980-04-22 | 1984-01-03 | Polaroid Corporation | Copolymeric mordants |
| US4340522A (en) | 1980-04-22 | 1982-07-20 | Polaroid Corporation | Process for preparing cationic polymers |
| US4322489A (en) | 1980-04-22 | 1982-03-30 | Polaroid Corporation | Copolymeric mordants and photographic products and processes utilizing same |
| US4503138A (en) | 1983-09-01 | 1985-03-05 | Polaroid Corporation | Image-receiving element with unitary image-receiving and decolorizing layer |
| US4563411A (en) | 1984-08-17 | 1986-01-07 | Polaroid Corporation | Copolymeric mordants and photographic products and processes containing same |
| US4931223A (en) * | 1986-07-24 | 1990-06-05 | Tropix, Inc. | Methods of using chemiluminescent 1,2-dioxetanes |
| CA1340590C (en) | 1986-07-24 | 1999-06-08 | John C. Voyta | Chemiluminescence enhancement |
| US4978614A (en) | 1988-10-26 | 1990-12-18 | Tropix, Inc. | Method of detecting a substance using enzymatically-induced decomposition of dioxetanes |
| US5112960A (en) * | 1989-07-17 | 1992-05-12 | Bronstein Irena Y | Chemiluminescent 3-(substituted adamant-2'-ylidene) 1,2-dioxetanes |
| US5089630A (en) | 1987-12-31 | 1992-02-18 | Bronstein Irena Y | Dioxetanes for use in assays |
| US5538847A (en) | 1989-07-17 | 1996-07-23 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US5582980A (en) * | 1989-07-17 | 1996-12-10 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| JP2552413B2 (ja) * | 1990-08-30 | 1996-11-13 | トロピックス・インコーポレーテッド | 化学発光性３ー（置換アダマントー２′ーイリデン）１，２ージオキセタン |
| US5744320A (en) | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| US6602657B1 (en) * | 1995-12-28 | 2003-08-05 | Tropix, Inc. | Multiple reporter gene assay |
-
1999
- 1999-12-14 AT AT99965243T patent/ATE441725T1/de not_active IP Right Cessation
- 1999-12-14 CA CA2353872A patent/CA2353872C/en not_active Expired - Fee Related
- 1999-12-14 JP JP2000588347A patent/JP4668418B2/ja not_active Expired - Fee Related
- 1999-12-14 WO PCT/US1999/029550 patent/WO2000036098A1/en not_active Ceased
- 1999-12-14 US US09/459,982 patent/US6586196B1/en not_active Expired - Lifetime
- 1999-12-14 DE DE69941367T patent/DE69941367D1/de not_active Expired - Lifetime
- 1999-12-14 AU AU31201/00A patent/AU781255B2/en not_active Ceased
- 1999-12-14 EP EP99965243A patent/EP1151090B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2353872A1 (en) | 2000-06-22 |
| AU781255B2 (en) | 2005-05-12 |
| EP1151090A4 (en) | 2007-05-02 |
| JP4668418B2 (ja) | 2011-04-13 |
| EP1151090B1 (en) | 2009-09-02 |
| EP1151090A1 (en) | 2001-11-07 |
| WO2000036098B1 (en) | 2000-07-27 |
| CA2353872C (en) | 2011-05-03 |
| WO2000036098A1 (en) | 2000-06-22 |
| JP2003520017A (ja) | 2003-07-02 |
| US6586196B1 (en) | 2003-07-01 |
| AU3120100A (en) | 2000-07-03 |
| DE69941367D1 (de) | 2009-10-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |