ATE432472T1 - Endogene, konstitutiv aktivierte g-protein gekoppelte waisenrezeptoren - Google Patents
Endogene, konstitutiv aktivierte g-protein gekoppelte waisenrezeptorenInfo
- Publication number
- ATE432472T1 ATE432472T1 AT99941990T AT99941990T ATE432472T1 AT E432472 T1 ATE432472 T1 AT E432472T1 AT 99941990 T AT99941990 T AT 99941990T AT 99941990 T AT99941990 T AT 99941990T AT E432472 T1 ATE432472 T1 AT E432472T1
- Authority
- AT
- Austria
- Prior art keywords
- endogenous
- constitutively activated
- protein coupled
- orphan receptors
- coupled orphan
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/30—Oxygen or sulfur atoms
- C07D233/42—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9487998P | 1998-07-31 | 1998-07-31 | |
| US10630098P | 1998-10-30 | 1998-10-30 | |
| US11090698P | 1998-12-04 | 1998-12-04 | |
| US12185199P | 1999-02-26 | 1999-02-26 | |
| PCT/US1999/017425 WO2000006597A2 (en) | 1998-07-31 | 1999-07-30 | Endogenous constitutively activated g protein-coupled orphan receptors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE432472T1 true ATE432472T1 (de) | 2009-06-15 |
Family
ID=27492754
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99941990T ATE432472T1 (de) | 1998-07-31 | 1999-07-30 | Endogene, konstitutiv aktivierte g-protein gekoppelte waisenrezeptoren |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1095275B1 (de) |
| JP (1) | JP2002521681A (de) |
| CN (1) | CN1231762C (de) |
| AT (1) | ATE432472T1 (de) |
| AU (1) | AU751080B2 (de) |
| CA (1) | CA2338543C (de) |
| DE (1) | DE69940923D1 (de) |
| DK (1) | DK1095275T3 (de) |
| IL (1) | IL140858A0 (de) |
| MX (1) | MXPA01001176A (de) |
| NO (1) | NO20010509L (de) |
| NZ (1) | NZ509429A (de) |
| WO (1) | WO2000006597A2 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6555339B1 (en) * | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
| CA2402392A1 (en) * | 2000-04-07 | 2001-10-18 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated known g protein-coupled receptors |
| AU2003218234A1 (en) * | 2002-03-15 | 2003-09-29 | Arena Pharmaceuticals, Inc. | Methods of expressing non-endogenous g protein coupled receptors in cells |
| WO2003081256A2 (en) * | 2002-03-22 | 2003-10-02 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human g protein-coupled orphan receptor 21 (gpr21) |
| WO2004015422A2 (en) * | 2002-08-05 | 2004-02-19 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with ovarian cancer g-protein coupled receptor 1 (ogr-1) |
| EP1578798A1 (de) * | 2002-12-20 | 2005-09-28 | 7TM Pharma A/S | Ghrelinrezeptor-inverseagonisten zur regulierung des verhaltens der ernährung |
| WO2005095990A1 (en) * | 2004-03-25 | 2005-10-13 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g-protein coupled receptor 52 (gpr52) |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0830600B1 (de) * | 1995-06-07 | 2003-08-27 | Praecis Pharmaceuticals Incorporated | Funktioneller bioassay für an g-protein gekoppelte rezeptoragonisten und antagonisten |
| CA2232733A1 (en) * | 1995-09-20 | 1997-03-27 | Orikkalapat Prem Das | Yeast receptor and g-protein fusion protein |
| AU743259B2 (en) * | 1997-04-14 | 2002-01-24 | Arena Pharmaceuticals, Inc. | A method of identifying modulators of cell surface membrane receptors useful in the treatment of disease |
-
1999
- 1999-07-30 EP EP99941990A patent/EP1095275B1/de not_active Expired - Lifetime
- 1999-07-30 MX MXPA01001176A patent/MXPA01001176A/es unknown
- 1999-07-30 CA CA002338543A patent/CA2338543C/en not_active Expired - Fee Related
- 1999-07-30 IL IL14085899A patent/IL140858A0/xx unknown
- 1999-07-30 AU AU55459/99A patent/AU751080B2/en not_active Ceased
- 1999-07-30 JP JP2000562393A patent/JP2002521681A/ja not_active Ceased
- 1999-07-30 WO PCT/US1999/017425 patent/WO2000006597A2/en active Application Filing
- 1999-07-30 DK DK99941990T patent/DK1095275T3/da active
- 1999-07-30 NZ NZ509429A patent/NZ509429A/en not_active IP Right Cessation
- 1999-07-30 CN CNB998122653A patent/CN1231762C/zh not_active Expired - Fee Related
- 1999-07-30 DE DE69940923T patent/DE69940923D1/de not_active Expired - Lifetime
- 1999-07-30 AT AT99941990T patent/ATE432472T1/de not_active IP Right Cessation
-
2001
- 2001-01-30 NO NO20010509A patent/NO20010509L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1095275A2 (de) | 2001-05-02 |
| DE69940923D1 (de) | 2009-07-09 |
| IL140858A0 (en) | 2002-02-10 |
| CN1231762C (zh) | 2005-12-14 |
| NZ509429A (en) | 2002-06-28 |
| EP1095275B1 (de) | 2009-05-27 |
| CA2338543A1 (en) | 2000-02-10 |
| AU751080B2 (en) | 2002-08-08 |
| CN1323396A (zh) | 2001-11-21 |
| NO20010509L (no) | 2001-03-19 |
| WO2000006597A9 (en) | 2000-07-13 |
| WO2000006597A2 (en) | 2000-02-10 |
| MXPA01001176A (es) | 2005-07-25 |
| NO20010509D0 (no) | 2001-01-30 |
| WO2000006597A3 (en) | 2000-05-18 |
| DK1095275T3 (da) | 2009-09-28 |
| AU5545999A (en) | 2000-02-21 |
| JP2002521681A (ja) | 2002-07-16 |
| CA2338543C (en) | 2009-12-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE325132T1 (de) | G-protein gekoppelter rezeptor | |
| DK1199069T3 (da) | Anvendelse af en estrogenagonist/-antagonist til forbedring eller bibeholdelse af urogenital sundhed | |
| ATE344241T1 (de) | Benzyliden-1,3-dihydro-indol-2-on-derivate als inhibitoren von rezeptor tyrosine kinasesn, insbesondere von raf kinasen | |
| LTPA2014028I1 (lt) | Pakeistieji 3-cianochinolinai kaip proteintirozinkinazės inhibitoriai | |
| CY1107821T1 (el) | Πολυπεπτιδιο παραγοντα viii με ενεργοτητα παραγοντα viii:c | |
| EA200400816A1 (ru) | Замещенные аналоги хиназолин-4-иламина в качестве модуляторов капсаицина | |
| DE69728893T2 (de) | N-aryl substituierte tetrahydrochinoline ligande für retinoidrezeptoren mit agonist, antagonist oder inverser agonist wirkung | |
| DK1885746T3 (da) | Sammensætninger relateret til opløselige G-protein-koblede receptorer (sGPCRs) | |
| BR0111298A (pt) | Moduladores seletivos dos receptores de andrógenos e métodos para identificação, projeto e uso dos mesmos | |
| EA200501724A1 (ru) | Соединения, специфичные к меланокортиновым рецепторам | |
| DE69711519T2 (de) | Carbazolanaloge als selektive beta3-adrenergische Agonisten | |
| TR199801679T2 (xx) | Osteoporoz i�in birle�tirme terapisi. | |
| BR0110079A (pt) | Combinação de compostos orgânicos | |
| BRPI0410884A (pt) | composição de ração para uso em um animal de estimação, e, método para o controle de peso em um animal de estimação | |
| BR0007864A (pt) | Composto, e, uso de um composto | |
| PT1086082E (pt) | Aminas olefinicas substituidas com arilo e seu uso como agonistas de receptores colinergicos | |
| EE04141B1 (et) | 5-HT tagasihaarde inhibiitori kombinatsioon h5-HT1B antagonisti või osalise agonistiga | |
| ATE432472T1 (de) | Endogene, konstitutiv aktivierte g-protein gekoppelte waisenrezeptoren | |
| ATE322503T1 (de) | Gefrierschutzprotein | |
| BR0108454A (pt) | Métodos para identificação e uso de antagonistas de receptor de adenosina a(2b) papa mediar a proliferação celular em mamìferos | |
| BR0317708A (pt) | Composto, composição farmacêutica, e, uso de um composto | |
| BR0318631A (pt) | os agonistas receptores peptìdeo-1 similares ao glucagon, a preparação e o uso do mesmo | |
| DK0862627T3 (da) | Neuropeptid Y-Y5 receptor | |
| BR0010882A (pt) | Agonistas receptores de adenosina a1 oralmente ativos e processo para uso de tal composição | |
| ZA200210012B (en) | Structure of G-protein (RGS4) and methods of identifying agonists and antagonists using same. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |