ATE429444T1 - Neues carbamyliertes epo und verfahren zu dessen herstellung - Google Patents

Neues carbamyliertes epo und verfahren zu dessen herstellung

Info

Publication number
ATE429444T1
ATE429444T1 AT05755533T AT05755533T ATE429444T1 AT E429444 T1 ATE429444 T1 AT E429444T1 AT 05755533 T AT05755533 T AT 05755533T AT 05755533 T AT05755533 T AT 05755533T AT E429444 T1 ATE429444 T1 AT E429444T1
Authority
AT
Austria
Prior art keywords
production
new
carbamylated epo
carbamylated
epo
Prior art date
Application number
AT05755533T
Other languages
English (en)
Inventor
Soren Christensen
Lars Foldager
Jesper Valbjyrn
Marianne Thuesen
Anders Pedersen
Morten Munk
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE429444T1 publication Critical patent/ATE429444T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/505Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1816Erythropoietin [EPO]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05755533T 2004-07-07 2005-07-07 Neues carbamyliertes epo und verfahren zu dessen herstellung ATE429444T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US58637004P 2004-07-07 2004-07-07
DKPA200401075 2004-07-07
US69387005P 2005-06-23 2005-06-23
PCT/DK2005/000477 WO2006002646A2 (en) 2004-07-07 2005-07-07 Novel carbamylated epo and method for its production

Publications (1)

Publication Number Publication Date
ATE429444T1 true ATE429444T1 (de) 2009-05-15

Family

ID=34979159

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05755533T ATE429444T1 (de) 2004-07-07 2005-07-07 Neues carbamyliertes epo und verfahren zu dessen herstellung

Country Status (19)

Country Link
EP (1) EP1781697B1 (de)
JP (1) JP5025470B2 (de)
AT (1) ATE429444T1 (de)
AU (1) AU2005259689B2 (de)
BR (1) BRPI0513029A (de)
CA (1) CA2572643A1 (de)
CY (1) CY1109232T1 (de)
DE (1) DE602005014117D1 (de)
DK (1) DK1781697T3 (de)
EA (1) EA011586B1 (de)
ES (1) ES2325034T3 (de)
HR (1) HRP20090343T1 (de)
IL (1) IL180518A0 (de)
MX (1) MXPA06014742A (de)
NO (1) NO20070687L (de)
PL (1) PL1781697T3 (de)
PT (1) PT1781697E (de)
SI (1) SI1781697T1 (de)
WO (1) WO2006002646A2 (de)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7718363B2 (en) 2003-04-25 2010-05-18 The Kenneth S. Warren Institute, Inc. Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds
JP2008505184A (ja) * 2004-07-02 2008-02-21 ザ ケネス エス.ウォーレン インスティテュート,インコーポレーテッド 完全にカルバミル化されたエリトロポイエチンを生成する方法
DE102006004008A1 (de) 2006-01-27 2007-08-02 Hannelore Prof. Dr. Dr. Ehrenreich Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose
US7811560B2 (en) * 2006-01-30 2010-10-12 Auxilium Us Holdings, Llc Compositions and methods for treating collagen-mediated diseases
DK1961821T3 (da) 2007-02-22 2009-10-12 Polymun Scient Immunbio Forsch Erythropoietin-fusionsprotein
AR065613A1 (es) * 2007-03-09 2009-06-17 Chugai Pharmaceutical Co Ltd Agentes de proteccion para organos transplantados
CA2701032C (en) 2007-09-27 2021-01-26 Amgen Inc. Pharmaceutical formulations
ES2962777T3 (es) 2007-11-15 2024-03-21 Amgen Inc Formulación acuosa de anticuerpos estabilizada por antioxidantes para la administración parenteral
MX2010008096A (es) 2008-01-25 2010-09-22 Amgen Inc Anticuerpos de ferroportina y metodos de uso.
EP2620448A1 (de) 2008-05-01 2013-07-31 Amgen Inc. Anti-hepcidin-antikörper und Verfahren zu ihrer Verwendung
HUE035168T2 (en) 2008-09-26 2018-05-02 Ambrx Inc Modified animal erythropoietin polypeptides and their applications
WO2010056981A2 (en) 2008-11-13 2010-05-20 Massachusetts General Hospital Methods and compositions for regulating iron homeostasis by modulation bmp-6
AU2010310457B2 (en) 2009-10-23 2015-07-02 Amgen Inc. Vial adapter and system
TW201129374A (en) 2009-10-26 2011-09-01 Lundbeck & Co As H Use of carbamylated erythropoietin for the treatment of Friedreich's ataxia
TW201129375A (en) 2009-11-18 2011-09-01 Lundbeck & Co As H Treatment of acute ischemic stroke or intracranial bleeding with tPa and carbamylated erythropoietin
CN103025369B (zh) 2010-06-07 2016-07-06 安姆根有限公司 药物递送装置
TW201213807A (en) 2010-07-19 2012-04-01 Lundbeck & Co As H Bioassay for the measurement of CEPO concentration and activity
WO2012069474A2 (en) 2010-11-24 2012-05-31 H. Lundbeck A/S A method for reducing potential virus burden in a sample by cyanate treatment
US9480624B2 (en) 2011-03-31 2016-11-01 Amgen Inc. Vial adapter and system
CA3145238A1 (en) 2011-04-20 2012-10-26 Amgen Inc. Autoinjector apparatus
IL308846B2 (en) 2011-10-14 2025-03-01 Amgen Inc Injector and assembly method
NZ766918A (en) 2012-01-12 2023-03-31 Auxilium Int Holdings Inc Clostridium histolyticum enzymes and methods for the use thereof
US12115341B2 (en) 2012-11-21 2024-10-15 Amgen Inc. Drug delivery device
TWI580452B (zh) 2013-03-15 2017-05-01 安美基公司 用於注射器之匣盒、注射器及使用包括自動注射器及匣盒之設備之方法
TWI580451B (zh) 2013-03-15 2017-05-01 安美基公司 用於注射器之匣盒及使用具有自動注射器及匣盒之自動注射器設備之方法
ES2695166T3 (es) 2013-03-15 2019-01-02 Intrinsic Lifesciences Llc Anticuerpos antihepcidina y usos de los mismos
CA2903495C (en) 2013-03-15 2021-05-25 Amgen Inc. Body contour adaptable autoinjector device
BR112015024282B1 (pt) 2013-03-22 2022-05-17 Amgen Inc Injetor e método de montagem do injetor
AU2014340174B2 (en) 2013-10-24 2019-09-12 Amgen Inc. Drug delivery system with temperature-sensitive control
CN105873626A (zh) 2013-10-24 2016-08-17 美国安进公司 注射器和组装方法
WO2015119906A1 (en) 2014-02-05 2015-08-13 Amgen Inc. Drug delivery system with electromagnetic field generator
SG11201609219QA (en) 2014-05-07 2016-12-29 Amgen Inc Autoinjector with shock reducing elements
CN106488782B (zh) 2014-06-03 2021-03-09 安姆根有限公司 用于辅助药物递送装置的用户的装置和方法
CA2961917A1 (en) 2014-09-22 2016-03-31 Intrinsic Lifesciences Llc Humanized anti-hepcidin antibodies and uses thereof
US10695506B2 (en) 2014-10-14 2020-06-30 Amgen Inc. Drug injection device with visual and audio indicators
JP2017538512A (ja) 2014-12-19 2017-12-28 アムジエン・インコーポレーテツド ライブボタンまたはユーザインタフェースフィールドを含む薬物送達装置
US10799630B2 (en) 2014-12-19 2020-10-13 Amgen Inc. Drug delivery device with proximity sensor
EP3556411B1 (de) 2015-02-17 2021-06-30 Amgen Inc. Arzneimittelabgabevorrichtung mit vakuumunterstützter sicherung und/oder rückkopplung
ES2905870T3 (es) 2015-02-27 2022-04-12 Amgen Inc Dispositivo de suministro de fármacos que tiene un mecanismo de protección de aguja con un umbral de resistencia ajustable al movimiento de la protección de aguja
WO2017039786A1 (en) 2015-09-02 2017-03-09 Amgen Inc. Syringe assembly adapter for a syringe
WO2017100501A1 (en) 2015-12-09 2017-06-15 Amgen Inc. Auto-injector with signaling cap
WO2017120178A1 (en) 2016-01-06 2017-07-13 Amgen Inc. Auto-injector with signaling electronics
ES2814287T3 (es) 2016-03-15 2021-03-26 Amgen Inc Reducir la probabilidad de rotura de cristal en dispositivos de administración de fármaco
US11541168B2 (en) 2016-04-29 2023-01-03 Amgen Inc. Drug delivery device with messaging label
US11389588B2 (en) 2016-05-02 2022-07-19 Amgen Inc. Syringe adapter and guide for filling an on-body injector
MX2018013616A (es) 2016-05-13 2019-02-21 Amgen Inc Montaje de cubierta protectora de vial.
US11238150B2 (en) 2016-05-16 2022-02-01 Amgen Inc. Data encryption in medical devices with limited computational capability
EP3465124A1 (de) 2016-06-03 2019-04-10 Amgen Inc. Wirkungstestvorrichtungen und verfahren für wirkstofffreisetzungsvorrichtungen
EP3478342B1 (de) 2016-07-01 2025-03-12 Amgen Inc. Arzneimittelabgabevorrichtung mit minimiertem teilebruchrisiko nach aufprallereignissen
US20190328965A1 (en) 2016-08-17 2019-10-31 Amgen Inc. Drug delivery device with placement detection
WO2018081234A1 (en) 2016-10-25 2018-05-03 Amgen Inc. On-body injector
EP3570917A1 (de) 2017-01-17 2019-11-27 Amgen Inc. Injektionsvorrichtungen und zugehörige verfahren zur verwendung sowie anordnung
EP3582825A1 (de) 2017-02-17 2019-12-25 Amgen Inc. Wirkstofffreisetzungsvorrichtung mit steriler fluidströmung und zugehöriges verfahren zur montage
MX2019009755A (es) 2017-02-17 2019-10-07 Amgen Inc Mecanismo de insercion para dispositivo de suministro de farmacos.
DK3589204T3 (da) 2017-03-01 2025-06-30 Endo Operations Ltd Apparat og fremgangsmåde til vurdering og behandling af cellulitis
WO2018165143A1 (en) 2017-03-06 2018-09-13 Amgen Inc. Drug delivery device with activation prevention feature
EP3592402A1 (de) 2017-03-07 2020-01-15 Amgen Inc. Nadeleinführung durch überdruck
IL268386B2 (en) 2017-03-09 2023-11-01 Amgen Inc Insertion mechanism for a drug delivery device
CN110446499A (zh) 2017-03-20 2019-11-12 豪夫迈·罗氏有限公司 一种体外糖基工程化红细胞生成刺激蛋白的方法
CN118325876A (zh) 2017-03-28 2024-07-12 恩多风投有限公司 生产胶原酶的改进方法
US11957883B2 (en) 2017-03-28 2024-04-16 Amgen Inc. Plunger rod and syringe assembly system and method
CN110709121B (zh) 2017-06-08 2022-06-24 安进公司 扭矩驱动式药物递送装置
EP3634539A1 (de) 2017-06-08 2020-04-15 Amgen Inc. Spritzenanordnung für eine wirkstofffreisetzungsvorrichtung und verfahren zur montage
AU2018288604B2 (en) 2017-06-22 2023-12-21 Amgen Inc. Device activation impact/shock reduction
MX2019015479A (es) 2017-06-23 2020-02-20 Amgen Inc Dispositivo electronico de administracion de farmacos con tapa accionada por un conjunto de conmutador.
WO2019014014A1 (en) 2017-07-14 2019-01-17 Amgen Inc. NEEDLE INSERTION-RETRACTING SYSTEM HAVING DOUBLE TORSION SPRING SYSTEM
EP4292576A3 (de) 2017-07-21 2024-01-17 Amgen Inc. Gasdurchlässiges dichtungselement für arzneimittelbehälter und verfahren zur montage
US11617837B2 (en) 2017-07-25 2023-04-04 Amgen Inc. Drug delivery device with gear module and related method of assembly
US11484648B2 (en) 2017-07-25 2022-11-01 Amgen Inc. Drug delivery device with container access system and related method of assembly
EP3664863A2 (de) 2017-08-09 2020-06-17 Amgen Inc. Hydraulisch-pneumatisches druckkammer-arzneimittelabgabesystem
EP3668567A1 (de) 2017-08-18 2020-06-24 Amgen Inc. Am körper tragbarer injektor mit sterilem klebepflaster
US11103636B2 (en) 2017-08-22 2021-08-31 Amgen Inc. Needle insertion mechanism for drug delivery device
MA50611A (fr) 2017-10-04 2020-08-12 Amgen Inc Adaptateur d'écoulement destiné à un dispositif d'administration de médicament
CN111132711B (zh) 2017-10-06 2022-07-01 安进公司 带有联锁组件的药物递送装置及相关组装方法
WO2019074579A1 (en) 2017-10-09 2019-04-18 Amgen Inc. DRUG DELIVERY DEVICE COMPRISING A DRIVE ASSEMBLY AND ASSEMBLY METHOD THEREOF
US11826480B2 (en) 2017-11-03 2023-11-28 Amgen Inc. Systems and approaches for sterilizing a drug delivery device
WO2019089178A1 (en) 2017-11-06 2019-05-09 Amgen Inc. Drug delivery device with placement and flow sensing
WO2019090303A1 (en) 2017-11-06 2019-05-09 Amgen Inc. Fill-finish assemblies and related methods
WO2019094138A1 (en) 2017-11-10 2019-05-16 Amgen Inc. Plungers for drug delivery devices
EP3710090A1 (de) 2017-11-16 2020-09-23 Amgen Inc. Türverriegelungsmechanismus für wirkstofffreisetzungsvorrichtung
EP3710089A1 (de) 2017-11-16 2020-09-23 Amgen Inc. Autoinjektor mit stillstands- und endpunktdetektion
US10835685B2 (en) 2018-05-30 2020-11-17 Amgen Inc. Thermal spring release mechanism for a drug delivery device
US11083840B2 (en) 2018-06-01 2021-08-10 Amgen Inc. Modular fluid path assemblies for drug delivery devices
WO2020023336A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Hybrid drug delivery devices with grip portion
MX2021000748A (es) 2018-07-24 2021-03-26 Amgen Inc Dispositivos de suministro para administrar farmacos.
US12303677B2 (en) 2018-07-24 2025-05-20 Amgen Inc. Hybrid drug delivery devices with optional grip portion and related method of preparation
CA3103682A1 (en) 2018-07-24 2020-01-30 Amgen Inc. Delivery devices for administering drugs
EP3829692A1 (de) 2018-07-31 2021-06-09 Amgen Inc. Flüssigkeitsweganordnungen für wirkstofffreisetzungsvorrichtung
MA53724A (fr) 2018-09-24 2021-12-29 Amgen Inc Systèmes et procédés de dosage interventionnel
WO2020068476A1 (en) 2018-09-28 2020-04-02 Amgen Inc. Muscle wire escapement activation assembly for a drug delivery device
CN117159846A (zh) 2018-10-02 2023-12-05 安进公司 具有内部力传递的用于药物递送的注射系统
MA53818A (fr) 2018-10-05 2022-01-12 Amgen Inc Dispositif d'administration de médicament ayant un indicateur de dose
EP3866889A1 (de) 2018-10-15 2021-08-25 Amgen Inc. Plattformmontageverfahren für medikamentenabgabevorrichtung
SG11202103800RA (en) 2018-10-15 2021-05-28 Amgen Inc Drug delivery device having damping mechanism
MA54057A (fr) 2018-11-01 2022-02-09 Amgen Inc Dispositifs d'administration de médicament à rétraction partielle d'élément d'administration de médicament
TWI831847B (zh) 2018-11-01 2024-02-11 美商安進公司 部分針頭縮回之藥物遞送裝置及其操作方法
EP3873566B1 (de) 2018-11-01 2024-11-27 Amgen Inc. Vorrichtung zur verabreichung von medikamenten mit teilweisem rückzug des medikamentenabgabeelements
MX2021012557A (es) 2019-04-24 2021-11-12 Amgen Inc Conjuntos y metodos de verificacion de esterilizacion de jeringuillas.
AU2020337250A1 (en) 2019-08-23 2022-03-03 Amgen Inc. Drug delivery device with configurable needle shield engagement components and related methods
RU2720103C1 (ru) * 2019-10-16 2020-04-24 Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") Способ коррекции нарушений микроциркуляции в плаценте карбамилированным дарбэпоэтином при ADMA-подобной модели преэклампсии
AU2022279223A1 (en) 2021-05-21 2023-10-19 Amgen Inc. Method of optimizing a filling recipe for a drug container
AU2023374183A1 (en) 2022-11-02 2025-03-20 F. Hoffmann-La Roche Ag Method for producing glycoprotein compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2215748C2 (ru) * 1999-04-09 2003-11-10 Сентро Де Инмунология Молекулар Способ получения рекомбинантного эритропоэтина человека и полученный эритропоэтин, фармацевтическая композиция
PA8536201A1 (es) * 2000-12-29 2002-08-29 Kenneth S Warren Inst Inc Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina
US20030072737A1 (en) * 2000-12-29 2003-04-17 Michael Brines Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs
KR20060013547A (ko) * 2003-05-19 2006-02-10 더 케네쓰 에스. 워렌 인스티튜트 인코포레이티드 확장된 치료 윈도우를 갖는, 반응성 세포, 조직 및 기관의보호, 회복 및 개선을 위한 조직 보호성 사이토카인

Also Published As

Publication number Publication date
NO20070687L (no) 2007-03-27
WO2006002646A2 (en) 2006-01-12
IL180518A0 (en) 2007-06-03
JP2008505133A (ja) 2008-02-21
EP1781697B1 (de) 2009-04-22
CA2572643A1 (en) 2006-01-12
AU2005259689B2 (en) 2011-10-06
EA200700255A1 (ru) 2007-06-29
EP1781697A2 (de) 2007-05-09
AU2005259689A1 (en) 2006-01-12
EA011586B1 (ru) 2009-04-28
DK1781697T3 (da) 2009-07-06
SI1781697T1 (sl) 2009-08-31
PL1781697T3 (pl) 2009-10-30
BRPI0513029A (pt) 2008-04-22
CY1109232T1 (el) 2014-07-02
DE602005014117D1 (de) 2009-06-04
ES2325034T3 (es) 2009-08-24
PT1781697E (pt) 2009-06-25
JP5025470B2 (ja) 2012-09-12
HRP20090343T1 (hr) 2009-07-31
WO2006002646A3 (en) 2006-04-13
MXPA06014742A (es) 2007-02-16
HK1109631A1 (en) 2008-06-13

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