ATE429444T1 - Neues carbamyliertes epo und verfahren zu dessen herstellung - Google Patents
Neues carbamyliertes epo und verfahren zu dessen herstellungInfo
- Publication number
- ATE429444T1 ATE429444T1 AT05755533T AT05755533T ATE429444T1 AT E429444 T1 ATE429444 T1 AT E429444T1 AT 05755533 T AT05755533 T AT 05755533T AT 05755533 T AT05755533 T AT 05755533T AT E429444 T1 ATE429444 T1 AT E429444T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- new
- carbamylated epo
- carbamylated
- epo
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/505—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1816—Erythropoietin [EPO]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Psychiatry (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US58637004P | 2004-07-07 | 2004-07-07 | |
DKPA200401075 | 2004-07-07 | ||
US69387005P | 2005-06-23 | 2005-06-23 | |
PCT/DK2005/000477 WO2006002646A2 (en) | 2004-07-07 | 2005-07-07 | Novel carbamylated epo and method for its production |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE429444T1 true ATE429444T1 (de) | 2009-05-15 |
Family
ID=34979159
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT05755533T ATE429444T1 (de) | 2004-07-07 | 2005-07-07 | Neues carbamyliertes epo und verfahren zu dessen herstellung |
Country Status (20)
Country | Link |
---|---|
EP (1) | EP1781697B1 (de) |
JP (1) | JP5025470B2 (de) |
AT (1) | ATE429444T1 (de) |
AU (1) | AU2005259689B2 (de) |
BR (1) | BRPI0513029A (de) |
CA (1) | CA2572643A1 (de) |
CY (1) | CY1109232T1 (de) |
DE (1) | DE602005014117D1 (de) |
DK (1) | DK1781697T3 (de) |
EA (1) | EA011586B1 (de) |
ES (1) | ES2325034T3 (de) |
HK (1) | HK1109631A1 (de) |
HR (1) | HRP20090343T1 (de) |
IL (1) | IL180518A0 (de) |
MX (1) | MXPA06014742A (de) |
NO (1) | NO20070687L (de) |
PL (1) | PL1781697T3 (de) |
PT (1) | PT1781697E (de) |
SI (1) | SI1781697T1 (de) |
WO (1) | WO2006002646A2 (de) |
Families Citing this family (102)
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US7718363B2 (en) | 2003-04-25 | 2010-05-18 | The Kenneth S. Warren Institute, Inc. | Tissue protective cytokine receptor complex and assays for identifying tissue protective compounds |
US20080305990A1 (en) * | 2004-07-02 | 2008-12-11 | The Kenneth S Warren Institute, Inc. | Method of Producing Fully Carbamylated Erythropoietin |
DE102006004008A1 (de) * | 2006-01-27 | 2007-08-02 | Hannelore Prof. Dr. Dr. Ehrenreich | Verfahren zur Behandlung und/oder Prophylaxe von Multipler Sklerose, sowie Verwendung von Erythropoietin zur Herstellung eines Arzneimittels zur intermittierenden Behandlung und/oder intermittierenden Prophylaxe von Multipler Sklerose |
US7811560B2 (en) * | 2006-01-30 | 2010-10-12 | Auxilium Us Holdings, Llc | Compositions and methods for treating collagen-mediated diseases |
DK1961821T3 (da) * | 2007-02-22 | 2009-10-12 | Polymun Scient Immunbio Forsch | Erythropoietin-fusionsprotein |
AR065613A1 (es) * | 2007-03-09 | 2009-06-17 | Chugai Pharmaceutical Co Ltd | Agentes de proteccion para organos transplantados |
EP2205280B1 (de) | 2007-09-27 | 2019-09-04 | Amgen Inc. | Pharmazeutische formulierungen |
EP2219602A1 (de) | 2007-11-15 | 2010-08-25 | Amgen, Inc | Wässrige formulierung von mit antioxidantien stabilisiertem erythropoese-stimulierendem protein zur parenteralen verabreichung |
EP2574628B1 (de) | 2008-01-25 | 2015-05-20 | Amgen Inc. | Ferroportin-Antikörper und Verwendungsverfahren |
WO2009139822A1 (en) | 2008-05-01 | 2009-11-19 | Amgen Inc. | Anti-hepcidin antibodies and methods of use |
CN102232085A (zh) | 2008-09-26 | 2011-11-02 | Ambrx公司 | 修饰的动物促红细胞生成素多肽和其用途 |
EP2349332B1 (de) | 2008-11-13 | 2019-10-23 | The General Hospital Corporation | Verfahren und zusammensetzungen zur regulierung der eisenhomöostase durch modulierung der bmp6-aktivität |
AU2010310457B2 (en) | 2009-10-23 | 2015-07-02 | Amgen Inc. | Vial adapter and system |
TW201129374A (en) | 2009-10-26 | 2011-09-01 | Lundbeck & Co As H | Use of carbamylated erythropoietin for the treatment of Friedreich's ataxia |
TW201129375A (en) | 2009-11-18 | 2011-09-01 | Lundbeck & Co As H | Treatment of acute ischemic stroke or intracranial bleeding with tPa and carbamylated erythropoietin |
HUE026173T2 (en) | 2010-06-07 | 2016-05-30 | Amgen Inc | pharmaceutical Pump |
TW201213807A (en) | 2010-07-19 | 2012-04-01 | Lundbeck & Co As H | Bioassay for the measurement of CEPO concentration and activity |
WO2012069474A2 (en) | 2010-11-24 | 2012-05-31 | H. Lundbeck A/S | A method for reducing potential virus burden in a sample by cyanate treatment |
EP2691065B1 (de) | 2011-03-31 | 2017-03-01 | Amgen Inc. | Fläschchenadapter und system damit |
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EP3584317B1 (de) | 2012-01-12 | 2021-11-24 | Endo Global Ventures | Clostridium histolyticum enzym |
EP4234694A3 (de) | 2012-11-21 | 2023-09-06 | Amgen Inc. | Arzneimittelabgabevorrichtung |
BR112015022042B1 (pt) | 2013-03-15 | 2023-01-10 | Amgen Inc | Injetor para injetar um produto terapêutico |
EP2968503B1 (de) | 2013-03-15 | 2018-08-15 | Intrinsic LifeSciences LLC | Anti-hepcidin-antikörper und verwendungen davon |
US10092703B2 (en) | 2013-03-15 | 2018-10-09 | Amgen Inc. | Drug cassette, autoinjector, and autoinjector system |
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CN105377327B (zh) | 2013-03-22 | 2021-06-22 | 安姆根有限公司 | 注射器及装配方法 |
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JP2017538512A (ja) | 2014-12-19 | 2017-12-28 | アムジエン・インコーポレーテツド | ライブボタンまたはユーザインタフェースフィールドを含む薬物送達装置 |
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WO2017039786A1 (en) | 2015-09-02 | 2017-03-09 | Amgen Inc. | Syringe assembly adapter for a syringe |
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US11541168B2 (en) | 2016-04-29 | 2023-01-03 | Amgen Inc. | Drug delivery device with messaging label |
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EP3478342A1 (de) | 2016-07-01 | 2019-05-08 | Amgen Inc. | Arzneimittelabgabevorrichtung mit minimiertem teilebruchrisiko nach aufprallereignissen |
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US20200261643A1 (en) | 2016-10-25 | 2020-08-20 | Amgen Inc. | On-body injector |
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JP2020511499A (ja) | 2017-03-20 | 2020-04-16 | エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft | 赤血球生成刺激タンパク質のインビトロでの糖鎖改変のための方法 |
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CN110709121B (zh) | 2017-06-08 | 2022-06-24 | 安进公司 | 扭矩驱动式药物递送装置 |
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CN112351804A (zh) | 2018-07-24 | 2021-02-09 | 安进公司 | 用于施用药物的输送装置 |
EP3826701A1 (de) | 2018-07-24 | 2021-06-02 | Amgen Inc. | Ausgabevorrichtung zur verabreichung von arzneimitteln |
WO2020023336A1 (en) | 2018-07-24 | 2020-01-30 | Amgen Inc. | Hybrid drug delivery devices with grip portion |
US20210260279A1 (en) | 2018-07-24 | 2021-08-26 | Amgen Inc. | Hybrid drug delivery devices with optional grip portion and related method of preparation |
US20210228797A1 (en) | 2018-07-31 | 2021-07-29 | Amgen Inc. | Fluid path assembly for a drug delivery device |
JP2022500095A (ja) | 2018-09-24 | 2022-01-04 | アムジエン・インコーポレーテツド | インターベンション投薬システム及び方法 |
WO2020068476A1 (en) | 2018-09-28 | 2020-04-02 | Amgen Inc. | Muscle wire escapement activation assembly for a drug delivery device |
AU2019352616A1 (en) | 2018-10-02 | 2021-03-18 | Amgen Inc. | Injection systems for drug delivery with internal force transmission |
CA3112214A1 (en) | 2018-10-05 | 2020-04-09 | Amgen Inc. | Drug delivery device having dose indicator |
CN112689523A (zh) | 2018-10-15 | 2021-04-20 | 安进公司 | 用于药物递送装置的平台组装方法 |
MA53912A (fr) | 2018-10-15 | 2022-01-19 | Amgen Inc | Dispositif d'administration de médicament comprenant un mécanisme d'amortissement |
TWI831847B (zh) | 2018-11-01 | 2024-02-11 | 美商安進公司 | 部分針頭縮回之藥物遞送裝置及其操作方法 |
MA54048A (fr) | 2018-11-01 | 2022-02-09 | Amgen Inc | Dispositifs d'administration de médicament avec rétraction partielle de l'organe d'administration de médicament |
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JP7510952B2 (ja) | 2019-04-24 | 2024-07-04 | アムジエン・インコーポレーテツド | シリンジ滅菌確認アセンブリ及び方法 |
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RU2720103C1 (ru) * | 2019-10-16 | 2020-04-24 | Федеральное государственное автономное образовательное учреждение высшего образования "Белгородский государственный национальный исследовательский университет" (НИУ "БелГУ") | Способ коррекции нарушений микроциркуляции в плаценте карбамилированным дарбэпоэтином при ADMA-подобной модели преэклампсии |
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Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2215748C2 (ru) * | 1999-04-09 | 2003-11-10 | Сентро Де Инмунология Молекулар | Способ получения рекомбинантного эритропоэтина человека и полученный эритропоэтин, фармацевтическая композиция |
PA8536201A1 (es) * | 2000-12-29 | 2002-08-29 | Kenneth S Warren Inst Inc | Protección y mejoramiento de células, tejidos y órganos que responden a la eritropoyetina |
US20030072737A1 (en) * | 2000-12-29 | 2003-04-17 | Michael Brines | Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs |
MXPA05012515A (es) * | 2003-05-19 | 2006-05-25 | Kenneth S Warren Inst Inc | Citocinas protectoras de tejido para la proteccion, restablecimiento y potenciacion de celulas, tejidos y organos sensibles, con una ventana terapeutica ampliada. |
-
2005
- 2005-07-07 EA EA200700255A patent/EA011586B1/ru not_active IP Right Cessation
- 2005-07-07 PL PL05755533T patent/PL1781697T3/pl unknown
- 2005-07-07 AT AT05755533T patent/ATE429444T1/de active
- 2005-07-07 JP JP2007519619A patent/JP5025470B2/ja not_active Expired - Fee Related
- 2005-07-07 BR BRPI0513029-8A patent/BRPI0513029A/pt not_active IP Right Cessation
- 2005-07-07 WO PCT/DK2005/000477 patent/WO2006002646A2/en active Application Filing
- 2005-07-07 PT PT05755533T patent/PT1781697E/pt unknown
- 2005-07-07 CA CA002572643A patent/CA2572643A1/en not_active Abandoned
- 2005-07-07 MX MXPA06014742A patent/MXPA06014742A/es active IP Right Grant
- 2005-07-07 EP EP05755533A patent/EP1781697B1/de active Active
- 2005-07-07 DE DE602005014117T patent/DE602005014117D1/de active Active
- 2005-07-07 DK DK05755533T patent/DK1781697T3/da active
- 2005-07-07 ES ES05755533T patent/ES2325034T3/es active Active
- 2005-07-07 AU AU2005259689A patent/AU2005259689B2/en not_active Ceased
- 2005-07-07 SI SI200530707T patent/SI1781697T1/sl unknown
-
2007
- 2007-01-02 IL IL180518A patent/IL180518A0/en unknown
- 2007-02-06 NO NO20070687A patent/NO20070687L/no not_active Application Discontinuation
-
2008
- 2008-01-10 HK HK08100325.8A patent/HK1109631A1/xx not_active IP Right Cessation
-
2009
- 2009-06-15 HR HR20090343T patent/HRP20090343T1/xx unknown
- 2009-07-14 CY CY20091100734T patent/CY1109232T1/el unknown
Also Published As
Publication number | Publication date |
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AU2005259689B2 (en) | 2011-10-06 |
PT1781697E (pt) | 2009-06-25 |
EA011586B1 (ru) | 2009-04-28 |
CY1109232T1 (el) | 2014-07-02 |
DE602005014117D1 (de) | 2009-06-04 |
JP5025470B2 (ja) | 2012-09-12 |
HK1109631A1 (en) | 2008-06-13 |
EA200700255A1 (ru) | 2007-06-29 |
EP1781697A2 (de) | 2007-05-09 |
SI1781697T1 (sl) | 2009-08-31 |
PL1781697T3 (pl) | 2009-10-30 |
EP1781697B1 (de) | 2009-04-22 |
WO2006002646A3 (en) | 2006-04-13 |
JP2008505133A (ja) | 2008-02-21 |
MXPA06014742A (es) | 2007-02-16 |
WO2006002646A2 (en) | 2006-01-12 |
DK1781697T3 (da) | 2009-07-06 |
ES2325034T3 (es) | 2009-08-24 |
IL180518A0 (en) | 2007-06-03 |
NO20070687L (no) | 2007-03-27 |
HRP20090343T1 (en) | 2009-07-31 |
BRPI0513029A (pt) | 2008-04-22 |
CA2572643A1 (en) | 2006-01-12 |
AU2005259689A1 (en) | 2006-01-12 |
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