ATE428797T1 - Enzymatische umsetzung von oligopeptidamiden zu oligopeptidalkylestern - Google Patents
Enzymatische umsetzung von oligopeptidamiden zu oligopeptidalkylesternInfo
- Publication number
- ATE428797T1 ATE428797T1 AT06806395T AT06806395T ATE428797T1 AT E428797 T1 ATE428797 T1 AT E428797T1 AT 06806395 T AT06806395 T AT 06806395T AT 06806395 T AT06806395 T AT 06806395T AT E428797 T1 ATE428797 T1 AT E428797T1
- Authority
- AT
- Austria
- Prior art keywords
- oligopeptide
- alkylesters
- amides
- terminal
- enzymatic conversion
- Prior art date
Links
- 108010038807 Oligopeptides Proteins 0.000 title abstract 7
- 102000015636 Oligopeptides Human genes 0.000 title abstract 7
- 230000002255 enzymatic effect Effects 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title 1
- 238000006243 chemical reaction Methods 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 210000004899 c-terminal region Anatomy 0.000 abstract 3
- 125000005907 alkyl ester group Chemical group 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- 108700023418 Amidases Proteins 0.000 abstract 1
- KXDHJXZQYSOELW-UHFFFAOYSA-M Carbamate Chemical group NC([O-])=O KXDHJXZQYSOELW-UHFFFAOYSA-M 0.000 abstract 1
- SOWBFZRMHSNYGE-UHFFFAOYSA-N Monoamide-Oxalic acid Natural products NC(=O)C(O)=O SOWBFZRMHSNYGE-UHFFFAOYSA-N 0.000 abstract 1
- 125000005233 alkylalcohol group Chemical group 0.000 abstract 1
- 102000005922 amidase Human genes 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000008878 coupling Effects 0.000 abstract 1
- 238000010168 coupling process Methods 0.000 abstract 1
- 238000005859 coupling reaction Methods 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP05077419 | 2005-10-20 | ||
| PCT/EP2006/010089 WO2007045470A1 (en) | 2005-10-20 | 2006-10-19 | Enzymatic conversion of oligopeptide amides to oligopeptide alkylesters |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE428797T1 true ATE428797T1 (de) | 2009-05-15 |
Family
ID=36113820
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06806395T ATE428797T1 (de) | 2005-10-20 | 2006-10-19 | Enzymatische umsetzung von oligopeptidamiden zu oligopeptidalkylestern |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20090298118A1 (de) |
| EP (1) | EP1937826B1 (de) |
| JP (1) | JP4856184B2 (de) |
| CN (1) | CN101292040B (de) |
| AT (1) | ATE428797T1 (de) |
| DE (1) | DE602006006326D1 (de) |
| DK (1) | DK1937826T3 (de) |
| WO (1) | WO2007045470A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2198037B1 (de) * | 2007-10-12 | 2012-02-08 | DSM IP Assets B.V. | Chemisch-enzymatische Peptidsynthese mittels C-terminaler Ester-Umwandlung |
| BRPI0921081A2 (pt) * | 2008-11-19 | 2015-12-15 | Dsm Ip Assets Bv | síntese de peptídeos usando a ativação e o acoplamento enzimático. |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3793216A (en) * | 1971-12-06 | 1974-02-19 | Pennwalt Corp | Calcium hypochlorite composition |
| DE4014564C1 (de) * | 1990-05-07 | 1991-07-18 | Forschungszentrum Juelich Gmbh, 5170 Juelich, De | |
| JP3112090B2 (ja) * | 1994-05-09 | 2000-11-27 | デグサーヒュルス アクチェンゲゼルシャフト | ペプチドアミダーゼを含有する微生物の獲得方法、それにより得られた微生物、その中に含有されるペプチドアミダーゼ及びその使用 |
| NL1005901C2 (nl) * | 1997-04-25 | 1998-10-27 | Dsm Nv | Werkwijze voor de verestering van aminozuren en peptiden. |
-
2006
- 2006-10-19 AT AT06806395T patent/ATE428797T1/de active
- 2006-10-19 US US12/083,285 patent/US20090298118A1/en not_active Abandoned
- 2006-10-19 JP JP2008535968A patent/JP4856184B2/ja not_active Expired - Fee Related
- 2006-10-19 CN CN2006800390909A patent/CN101292040B/zh not_active Expired - Fee Related
- 2006-10-19 WO PCT/EP2006/010089 patent/WO2007045470A1/en not_active Ceased
- 2006-10-19 EP EP06806395A patent/EP1937826B1/de not_active Not-in-force
- 2006-10-19 DE DE602006006326T patent/DE602006006326D1/de active Active
- 2006-10-19 DK DK06806395T patent/DK1937826T3/da active
Also Published As
| Publication number | Publication date |
|---|---|
| EP1937826A1 (de) | 2008-07-02 |
| CN101292040A (zh) | 2008-10-22 |
| US20090298118A1 (en) | 2009-12-03 |
| JP4856184B2 (ja) | 2012-01-18 |
| CN101292040B (zh) | 2013-11-13 |
| DK1937826T3 (da) | 2009-07-06 |
| DE602006006326D1 (de) | 2009-05-28 |
| WO2007045470A1 (en) | 2007-04-26 |
| EP1937826B1 (de) | 2009-04-15 |
| JP2009512427A (ja) | 2009-03-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MX2007007030A (es) | Enzimas para procesamiento de almidon. | |
| Rohde et al. | Invited reviewligation—Desulfurization: A powerful combination in the synthesis of peptides and glycopeptides | |
| IN2014CN02050A (de) | ||
| Yamamura et al. | Enhancement of sortase A-mediated protein ligation by inducing a β-hairpin structure around the ligation site | |
| NZ595888A (en) | Method for the manufacture of degarelix | |
| WO2008133164A1 (ja) | アミノ末端1箇所で配向制御固定化された固定化タンパク質 | |
| MX2009005377A (es) | Sintesis de peptidos en fase solida con boc y fmoc. | |
| JPH0698788A (ja) | 水性溶液の形で保護された及び保護されていないジ− 及びオリゴペプチドの酵素による製造方法 | |
| JP2011139667A (ja) | プロリンおよびβ−アラニンをＮ末端に有するジペプチド、及びその環化ジペプチドの酵素合成法 | |
| WO2006009902A3 (en) | Non-natural amino acids | |
| ATE453664T1 (de) | Hausstaubmilbenallergen | |
| CN104284901A (zh) | 使用有机溶剂中的枯草杆菌蛋白酶的侧链被保护的寡肽片段缩合 | |
| Nakamura et al. | Synthesis of peptide thioesters via an N–S acyl shift reaction under mild acidic conditions on an N‐4, 5‐dimethoxy‐2‐mercaptobenzyl auxiliary group | |
| AU2003227907A8 (en) | Process for the synthesis of peptides amides by side-chain attachement to a solid phase | |
| ATE428797T1 (de) | Enzymatische umsetzung von oligopeptidamiden zu oligopeptidalkylestern | |
| BR0213779A (pt) | Molécula de ácido nucleico isolada, vetor, célula hospedeira, e, método para a preparação de um composto de quìmica fina | |
| de Beer et al. | Papain‐specific activating esters in aqueous dipeptide synthesis | |
| CA2509765A1 (en) | Novel peptide-producing enzyme, microbe producing the enzyme and method for dipeptide synthesis using them | |
| DE602007012436D1 (de) | Pseudoprolindipeptide | |
| ATE466874T1 (de) | Mit scytovirin der domäne 1 verwandte polypeptide | |
| ATE544864T1 (de) | Chemisch-enzymatische peptidsynthese mittels c- terminaler ester-umwandlung | |
| DK1979370T3 (da) | Selektiv enzymatisk hydrolyse af C-terminale tert-butyl-ester peptider | |
| de Beer et al. | Improving the carboxyamidomethyl ester for subtilisin A-catalysed peptide synthesis | |
| ZA200810024B (en) | Process for the synthesis of ibandronate sodium | |
| MY150639A (en) | T cell adhesion molecule and antibody thereto |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1937826 Country of ref document: EP |