ATE420082T1 - Benzothiophene als adenosinrezeptormodulatoren - Google Patents
Benzothiophene als adenosinrezeptormodulatorenInfo
- Publication number
- ATE420082T1 ATE420082T1 AT02792882T AT02792882T ATE420082T1 AT E420082 T1 ATE420082 T1 AT E420082T1 AT 02792882 T AT02792882 T AT 02792882T AT 02792882 T AT02792882 T AT 02792882T AT E420082 T1 ATE420082 T1 AT E420082T1
- Authority
- AT
- Austria
- Prior art keywords
- benzothiophenes
- receptor modulators
- adenosine receptor
- adenosine
- modulators
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pulmonology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01129269 | 2001-12-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE420082T1 true ATE420082T1 (de) | 2009-01-15 |
Family
ID=8179484
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02792882T ATE420082T1 (de) | 2001-12-12 | 2002-12-04 | Benzothiophene als adenosinrezeptormodulatoren |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US6730670B2 (de) |
| EP (1) | EP1456196B1 (de) |
| JP (1) | JP4197649B2 (de) |
| KR (1) | KR100581703B1 (de) |
| CN (1) | CN1296368C (de) |
| AR (1) | AR037791A1 (de) |
| AT (1) | ATE420082T1 (de) |
| AU (1) | AU2002358597C1 (de) |
| BR (1) | BR0214936A (de) |
| CA (1) | CA2469872A1 (de) |
| DE (1) | DE60230808D1 (de) |
| MX (1) | MXPA04005632A (de) |
| PL (1) | PL370980A1 (de) |
| RU (1) | RU2299882C2 (de) |
| WO (1) | WO2003053954A1 (de) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007505851A (ja) * | 2003-09-19 | 2007-03-15 | エフ．ホフマン−ラ ロシュ アーゲー | アデノシン受容体リガンドとしてのチアゾピリジン誘導体 |
| EP1874755A4 (de) * | 2005-04-20 | 2010-04-28 | Merck Sharp & Dohme | Benzothiophen-hydroxamsäure-derivate |
| BRPI0817897A2 (pt) * | 2007-11-02 | 2019-09-24 | Methylgene Inc | composto, composição, e, métodos de inibição da atividade hdac, e de tratamento de uma doença responsiva a um inibidor de atividade hdac |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5340833A (en) | 1992-05-01 | 1994-08-23 | Eisai Co., Ltd. | Urokinase inhibitors |
| US5350748A (en) * | 1993-08-18 | 1994-09-27 | Warner-Lambert Company | 3-thio or amino substituted-benzo[b]thiophene-2-carboxamides and 3-oxygen, thio, or amino substituted-benzofuran-2-carboxamides as inhibitors of cell adhesion |
| US5939432A (en) * | 1997-10-29 | 1999-08-17 | Medco Research, Inc. | Thiophenes useful for modulating the adenosine receptor |
| DE19749453A1 (de) * | 1997-11-10 | 1999-05-12 | Hoechst Marion Roussel De Gmbh | Sulfonamid-substituierte anellierte 5-Ring-Verbindungen, ihre Verwendung als Medikament sowie sie enthaltende pharmazeutische Zubereitungen |
| EA200100265A1 (ru) * | 1998-09-22 | 2001-10-22 | Киова Хакко Когио Ко., Лтд. | Производные [1,2,4]триазоло[1,5-c]пиримидина |
| CZ2003182A3 (cs) * | 2000-06-21 | 2003-06-18 | F. Hoffmann-La Roche Ag | Deriváty benzothiazolu |
| US6514989B1 (en) * | 2001-07-20 | 2003-02-04 | Hoffmann-La Roche Inc. | Aromatic and heteroaromatic substituted 1,2,4-triazolo pyridine derivatives |
-
2002
- 2002-12-04 WO PCT/EP2002/013704 patent/WO2003053954A1/en active Application Filing
- 2002-12-04 AT AT02792882T patent/ATE420082T1/de not_active IP Right Cessation
- 2002-12-04 MX MXPA04005632A patent/MXPA04005632A/es active IP Right Grant
- 2002-12-04 AU AU2002358597A patent/AU2002358597C1/en not_active Ceased
- 2002-12-04 CA CA002469872A patent/CA2469872A1/en not_active Abandoned
- 2002-12-04 KR KR1020047009058A patent/KR100581703B1/ko not_active IP Right Cessation
- 2002-12-04 EP EP02792882A patent/EP1456196B1/de not_active Expired - Lifetime
- 2002-12-04 DE DE60230808T patent/DE60230808D1/de not_active Expired - Fee Related
- 2002-12-04 CN CNB028248465A patent/CN1296368C/zh not_active Expired - Fee Related
- 2002-12-04 BR BR0214936-2A patent/BR0214936A/pt not_active IP Right Cessation
- 2002-12-04 PL PL02370980A patent/PL370980A1/xx unknown
- 2002-12-04 RU RU2004121682/04A patent/RU2299882C2/ru not_active IP Right Cessation
- 2002-12-04 JP JP2003554670A patent/JP4197649B2/ja not_active Expired - Fee Related
- 2002-12-10 US US10/315,821 patent/US6730670B2/en not_active Expired - Fee Related
- 2002-12-11 AR ARP020104799A patent/AR037791A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04005632A (es) | 2004-12-06 |
| WO2003053954A1 (en) | 2003-07-03 |
| AU2002358597A1 (en) | 2003-07-09 |
| AU2002358597C1 (en) | 2008-09-18 |
| CN1602309A (zh) | 2005-03-30 |
| EP1456196B1 (de) | 2009-01-07 |
| EP1456196A1 (de) | 2004-09-15 |
| BR0214936A (pt) | 2004-12-14 |
| RU2004121682A (ru) | 2005-05-27 |
| RU2299882C2 (ru) | 2007-05-27 |
| DE60230808D1 (de) | 2009-02-26 |
| US20030149030A1 (en) | 2003-08-07 |
| AR037791A1 (es) | 2004-12-01 |
| US6730670B2 (en) | 2004-05-04 |
| JP2006500313A (ja) | 2006-01-05 |
| KR100581703B1 (ko) | 2006-05-22 |
| CN1296368C (zh) | 2007-01-24 |
| AU2002358597B2 (en) | 2007-12-06 |
| JP4197649B2 (ja) | 2008-12-17 |
| CA2469872A1 (en) | 2003-07-03 |
| PL370980A1 (en) | 2005-06-13 |
| KR20040073477A (ko) | 2004-08-19 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE293962T1 (de) | Adenosin-rezeptor modulatoren | |
| ATE333449T1 (de) | 1,2,4-thiadiazoliumverbindungen als melanocortinrezeptor-modulatoren | |
| ZA200604645B (en) | Azabicyclic heterocycles as cannabinoid receptor modulators | |
| IL172577A0 (en) | Cannabinoid receptor modulator | |
| FR2824373B1 (fr) | Appareil amortisseur de choc | |
| IS7657A (is) | thíófen efnasambönd | |
| ATE268776T1 (de) | Benzodiazepinderivate als gaba-a- rezeptormodulatoren | |
| ATE277933T1 (de) | Thiophenverbindungen zur verwendung als antikrebsmittel | |
| DK1446379T3 (da) | Arylanilin-beta2-adrenergiske receptoragonister | |
| DE60327767D1 (de) | Tricyclische steroidhormonkernrezeptor-modulatoren | |
| EP1490043A4 (de) | Spirocyclische amide als cannabinoid-rezeptor-modulatoren | |
| DE60305903D1 (de) | Tropanderivative als ccr5-modulatoren | |
| PT1404667E (pt) | Derivados de piperidina uteis como moduladores da actividade do receptor de quimiocina | |
| ATE544762T1 (de) | Calcium rezeptor modulatoren | |
| ATE456558T1 (de) | Gabanerge modulatoren | |
| IL158038A0 (en) | Allosteric adenosine receptor modulators | |
| DE60330847D1 (de) | Benzofuranderivat | |
| DE60320167D1 (de) | Hydraulische dämpfende Hülse | |
| DE60201256D1 (de) | Elektrooptischer wanderwellenmodulator | |
| DE60210333D1 (de) | Tetracyclische heteroverbindungen als modulatoren des östrogenrezeptors | |
| ATE420082T1 (de) | Benzothiophene als adenosinrezeptormodulatoren | |
| DE60211116D1 (de) | Ausgleichsmechanismus | |
| DE602004014966D1 (de) | Benzofurane und benzothiophene | |
| SI1697370T1 (sl) | Azabiciklični heterocikli kot modulatorji kanabinoidnega receptorja | |
| SI1697371T1 (sl) | Azabiciklični heterocikli kot modulatorji kanabinoidnega receptorja |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |