ATE417129T1 - Nukleinsäureamplifikation mit nichtstandardbasen - Google Patents
Nukleinsäureamplifikation mit nichtstandardbasenInfo
- Publication number
- ATE417129T1 ATE417129T1 AT04703107T AT04703107T ATE417129T1 AT E417129 T1 ATE417129 T1 AT E417129T1 AT 04703107 T AT04703107 T AT 04703107T AT 04703107 T AT04703107 T AT 04703107T AT E417129 T1 ATE417129 T1 AT E417129T1
- Authority
- AT
- Austria
- Prior art keywords
- amplification
- standard
- nucleic acid
- standard bases
- acid amplification
- Prior art date
Links
- 230000003321 amplification Effects 0.000 title abstract 7
- 238000003199 nucleic acid amplification method Methods 0.000 title abstract 7
- 150000007523 nucleic acids Chemical class 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- 239000002777 nucleoside Substances 0.000 abstract 2
- -1 nucleoside triphosphates Chemical class 0.000 abstract 2
- 239000001226 triphosphate Substances 0.000 abstract 2
- 235000011178 triphosphate Nutrition 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000011541 reaction mixture Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US44092103P | 2003-01-17 | 2003-01-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE417129T1 true ATE417129T1 (de) | 2008-12-15 |
Family
ID=32771878
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04703107T ATE417129T1 (de) | 2003-01-17 | 2004-01-17 | Nukleinsäureamplifikation mit nichtstandardbasen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US7514212B2 (enExample) |
| EP (1) | EP1590482B1 (enExample) |
| JP (1) | JP4621197B2 (enExample) |
| AT (1) | ATE417129T1 (enExample) |
| AU (1) | AU2004206246B2 (enExample) |
| CA (1) | CA2513626C (enExample) |
| DE (1) | DE602004018270D1 (enExample) |
| WO (1) | WO2004065550A2 (enExample) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7498136B2 (en) | 2005-03-18 | 2009-03-03 | Eragen Biosciences, Inc. | Methods for detecting multiple species and subspecies of Neisseria |
| CA2610863C (en) * | 2005-06-07 | 2017-01-17 | Eragen Biosciences, Inc. | Methods for detection and typing of nucleic acids |
| US7759062B2 (en) | 2006-06-09 | 2010-07-20 | Third Wave Technologies, Inc. | T-structure invasive cleavage assays, consistent nucleic acid dispensing, and low level target nucleic acid detection |
| WO2009123216A1 (ja) | 2008-03-31 | 2009-10-08 | 独立行政法人理化学研究所 | 高選択・高効率でｐｃｒ増幅が可能な新規ｄｎａ |
| US10865431B1 (en) * | 2008-06-17 | 2020-12-15 | Steven A Benner | Polymerase incorporation of non-standard nucleotides |
| JP5715068B2 (ja) | 2009-01-30 | 2015-05-07 | マイクロニクス， インコーポレイテッド | 携帯型高利得蛍光検出システム |
| CN102639712A (zh) * | 2009-10-23 | 2012-08-15 | 卢米耐克斯公司 | 用于提高反应特异性的具有非标准碱基的扩增引物 |
| CN102740976B (zh) | 2010-01-29 | 2016-04-20 | 精密公司 | 取样-应答微流体盒 |
| US10752944B2 (en) | 2011-09-06 | 2020-08-25 | Gen-Probe Incorporated | Circularized templates for sequencing |
| EP3620533B1 (en) | 2011-09-06 | 2023-01-18 | Gen-Probe Incorporated | Closed nucleic acid structures |
| US20150259571A1 (en) * | 2012-08-31 | 2015-09-17 | Empire Technology Development Llc | Lignin membranes and coatings |
| EP2934751B1 (en) | 2012-12-21 | 2019-05-29 | Micronics, Inc. | Low elasticity films for microfluidic use |
| KR102102123B1 (ko) | 2012-12-21 | 2020-04-20 | 퍼킨엘머 헬스 사이언시즈, 아이엔씨. | 유체 공학 회로 및 관련 제조 방법 |
| EP2935559B1 (en) | 2012-12-21 | 2020-09-16 | PerkinElmer Health Sciences, Inc. | Fluorescence detection system |
| JP6484222B2 (ja) | 2013-05-07 | 2019-03-13 | マイクロニクス， インコーポレイテッド | 核酸の調製および分析のためのデバイス |
| EP2994750B1 (en) | 2013-05-07 | 2020-08-12 | PerkinElmer Health Sciences, Inc. | Microfluidic devices and methods for performing serum separation and blood cross-matching |
| CN105189750B (zh) | 2013-05-07 | 2020-07-28 | 珀金埃尔默健康科学有限公司 | 使用粘土矿物和碱性溶液制备含核酸样品的方法 |
| AU2016257426B2 (en) | 2015-05-01 | 2020-01-16 | Gen-Probe Incorporated | Multiplex invasive cleavage assays |
| WO2023043280A1 (ko) * | 2021-09-17 | 2023-03-23 | 주식회사 씨젠 | 합성 비자연 염기를 포함하는 태그 올리고뉴클레오타이드를 이용한 타겟 핵산 서열의 검출 |
Family Cites Families (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4458066A (en) * | 1980-02-29 | 1984-07-03 | University Patents, Inc. | Process for preparing polynucleotides |
| US5470974A (en) * | 1985-03-15 | 1995-11-28 | Neu-Gene Development Group | Uncharged polynucleotide-binding polymers |
| US4683202A (en) * | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| US4683195A (en) * | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
| US4996143A (en) * | 1985-12-23 | 1991-02-26 | Syngene, Inc. | Fluorescent stokes shift probes for polynucleotide hybridization |
| US4800159A (en) * | 1986-02-07 | 1989-01-24 | Cetus Corporation | Process for amplifying, detecting, and/or cloning nucleic acid sequences |
| US6054270A (en) * | 1988-05-03 | 2000-04-25 | Oxford Gene Technology Limited | Analying polynucleotide sequences |
| US6444798B1 (en) * | 1988-06-06 | 2002-09-03 | Steven Albert Benner | Chimeras of sulfur-linked oligonucleotide analogs and DNA and RNA |
| GB8827160D0 (en) | 1988-11-21 | 1988-12-29 | Apothekernes Lab | Detection & quantitative determination of rna & dna |
| GB8902689D0 (en) | 1989-02-07 | 1989-03-30 | Ici Plc | Assay method |
| US5856092A (en) * | 1989-02-13 | 1999-01-05 | Geneco Pty Ltd | Detection of a nucleic acid sequence or a change therein |
| GB8920097D0 (en) | 1989-09-06 | 1989-10-18 | Ici Plc | Amplification processes |
| US6007984A (en) * | 1989-11-01 | 1999-12-28 | Zeneca Limited | Detection of DNA/RNA by fluorescence polarization |
| US5412088A (en) * | 1989-11-20 | 1995-05-02 | Rutgers, The State University | 6-O-substituted guanosine derivatives |
| US5177064A (en) * | 1990-07-13 | 1993-01-05 | University Of Florida | Targeted drug delivery via phosphonate derivatives |
| US5210015A (en) * | 1990-08-06 | 1993-05-11 | Hoffman-La Roche Inc. | Homogeneous assay system using the nuclease activity of a nucleic acid polymerase |
| US6140496A (en) * | 1990-10-09 | 2000-10-31 | Benner; Steven Albert | Precursors for deoxyribonucleotides containing non-standard nucleosides |
| US5432272A (en) * | 1990-10-09 | 1995-07-11 | Benner; Steven A. | Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases |
| US5965364A (en) * | 1990-10-09 | 1999-10-12 | Benner; Steven Albert | Method for selecting functional deoxyribonucleotide derivatives |
| US6037120A (en) * | 1995-10-12 | 2000-03-14 | Benner; Steven Albert | Recognition of oligonucleotides containing non-standard base pairs |
| ES2101083T3 (es) * | 1990-12-21 | 1997-07-01 | Hoffmann La Roche | Tipado del dna hla dqbeta. |
| DE4129653A1 (de) * | 1991-09-06 | 1993-03-11 | Boehringer Mannheim Gmbh | Verfahren zum nachweis aehnlicher nukleinsaeuren |
| US5846717A (en) * | 1996-01-24 | 1998-12-08 | Third Wave Technologies, Inc. | Detection of nucleic acid sequences by invader-directed cleavage |
| US5958784A (en) * | 1992-03-25 | 1999-09-28 | Benner; Steven Albert | Predicting folded structures of proteins |
| AU3933393A (en) | 1993-03-17 | 1994-10-11 | City Of Hope | Nucleic acid sequences having single stranded ends |
| US5593836A (en) * | 1993-05-14 | 1997-01-14 | Niemiec; John T. | Primers and probes for detecting Pneumocystis carinii |
| US6156501A (en) | 1993-10-26 | 2000-12-05 | Affymetrix, Inc. | Arrays of modified nucleic acid probes and methods of use |
| WO1995021271A1 (en) * | 1994-02-07 | 1995-08-10 | Molecular Tool, Inc. | Ligase/polymerase-mediated genetic bit analysistm of single nucleotide polymorphisms and its use in genetic analysis |
| US5681702A (en) * | 1994-08-30 | 1997-10-28 | Chiron Corporation | Reduction of nonspecific hybridization by using novel base-pairing schemes |
| US5604097A (en) * | 1994-10-13 | 1997-02-18 | Spectragen, Inc. | Methods for sorting polynucleotides using oligonucleotide tags |
| US5763169A (en) * | 1995-01-13 | 1998-06-09 | Chiron Diagnostics Corporation | Nucleic acid probes for the detection and identification of fungi |
| GB9507238D0 (en) | 1995-04-07 | 1995-05-31 | Isis Innovation | Detecting dna sequence variations |
| US5736330A (en) * | 1995-10-11 | 1998-04-07 | Luminex Corporation | Method and compositions for flow cytometric determination of DNA sequences |
| US5705621A (en) * | 1995-11-17 | 1998-01-06 | Isis Pharmaceuticals, Inc. | Oligomeric phosphite, phosphodiester, Phosphorothioate and phosphorodithioate compounds and intermediates for preparing same |
| AU2320597A (en) * | 1996-03-19 | 1997-10-10 | Molecular Tool, Inc. | Method for determining the nucleotide sequence of a polynucleotide |
| US5780233A (en) | 1996-06-06 | 1998-07-14 | Wisconsin Alumni Research Foundation | Artificial mismatch hybridization |
| US6124092A (en) | 1996-10-04 | 2000-09-26 | The Perkin-Elmer Corporation | Multiplex polynucleotide capture methods and compositions |
| JP4185185B2 (ja) | 1997-05-08 | 2008-11-26 | 征夫 軽部 | 部分二重鎖ｄｎａを利用したｄｎａの検出方法 |
| US5928869A (en) * | 1997-05-30 | 1999-07-27 | Becton, Dickinson And Company | Detection of nucleic acids by fluorescence quenching |
| GB9725197D0 (en) * | 1997-11-29 | 1998-01-28 | Secr Defence | Detection system |
| JP4471494B2 (ja) * | 1998-05-14 | 2010-06-02 | ルミネックス コーポレイション | ダイオードレーザをベースとした測定装置 |
| WO1999067641A2 (en) | 1998-06-24 | 1999-12-29 | Illumina, Inc. | Decoding of array sensors with microspheres |
| US6528254B1 (en) * | 1999-10-29 | 2003-03-04 | Stratagene | Methods for detection of a target nucleic acid sequence |
| WO2001051669A2 (en) * | 2000-01-15 | 2001-07-19 | Genelabs Technologies, Inc. | Nucleic acid binding assay and selection method |
| AU7125401A (en) * | 2000-05-19 | 2001-12-03 | David J Marshall | Materials and methods for detection of nucleic acids |
| DE60137649D1 (de) * | 2000-10-14 | 2009-03-26 | Eragen Biosciences Inc | Nachweissysteme auf festen trägern und methoden zur verwendung von nicht-standardbasen |
| US7374882B2 (en) * | 2000-11-28 | 2008-05-20 | Riken | Method for base sequencing and biologically active nucleic acids |
| US20030194705A1 (en) * | 2002-03-01 | 2003-10-16 | Schroth Gary P. | Methods of using unnatural nucleobases for decoding |
-
2004
- 2004-01-17 EP EP04703107A patent/EP1590482B1/en not_active Expired - Lifetime
- 2004-01-17 WO PCT/US2004/001397 patent/WO2004065550A2/en not_active Ceased
- 2004-01-17 AT AT04703107T patent/ATE417129T1/de not_active IP Right Cessation
- 2004-01-17 AU AU2004206246A patent/AU2004206246B2/en not_active Expired
- 2004-01-17 JP JP2006501040A patent/JP4621197B2/ja not_active Expired - Fee Related
- 2004-01-17 DE DE602004018270T patent/DE602004018270D1/de not_active Expired - Lifetime
- 2004-01-17 US US10/542,464 patent/US7514212B2/en not_active Expired - Lifetime
- 2004-01-17 CA CA2513626A patent/CA2513626C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1590482A2 (en) | 2005-11-02 |
| US20070105099A1 (en) | 2007-05-10 |
| WO2004065550A2 (en) | 2004-08-05 |
| WO2004065550A3 (en) | 2004-12-23 |
| US7514212B2 (en) | 2009-04-07 |
| AU2004206246A1 (en) | 2004-08-05 |
| JP2006515760A (ja) | 2006-06-08 |
| JP4621197B2 (ja) | 2011-01-26 |
| AU2004206246B2 (en) | 2009-10-01 |
| CA2513626C (en) | 2013-03-19 |
| EP1590482A4 (en) | 2006-07-26 |
| EP1590482B1 (en) | 2008-12-10 |
| DE602004018270D1 (de) | 2009-01-22 |
| CA2513626A1 (en) | 2004-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE417129T1 (de) | Nukleinsäureamplifikation mit nichtstandardbasen | |
| WO2006076017A3 (en) | Methods and kits for identifying target nucleotides in mixed populations | |
| DE60034396D1 (de) | Reaktionsgemisch und Verfahren für RT-PCR mittels einer homopolymeren Nukleinsäure | |
| WO2008076842A3 (en) | Sequencing methods | |
| IS8314A (is) | Ákvörðun fjölkirnisraðar | |
| DE602006004435D1 (de) | Polymorphismusnachweisverfahren | |
| AU2003268397A1 (en) | Improved compositions and methods for cdna synthesis | |
| ATE370248T1 (de) | Methode zur quantifizierung von nukleinsäuren in echtzeit mittels effizienzkorrektur | |
| DE60022541D1 (de) | Polynukleotid amplifizierungsverfahren | |
| EP2272952B8 (en) | Thermostable or thermoactive DNA polymerase with attenuated 3'-5' exonuclease activity | |
| DE60230672D1 (de) | Nukleinsäureanreicherung | |
| ATE527380T1 (de) | Neue hot-start-nukleinsäureamplifikation | |
| WO2005061734A3 (en) | Double stranded linear nucleic acid probe and uses thereof | |
| EP1275715A4 (en) | METHOD OF AMPLIFYING NUCLEIC ACID USING DOUBLE-STRANDED NUCLEIC ACID AS A MODEL | |
| DK0726324T3 (da) | Anvendelse af exonuklease og/eller glycosylase som supplementer til antipolymeraseantistof til forøgelse af specification i polymerasekædereaktion | |
| SE0301951D0 (sv) | New method | |
| ATE538216T1 (de) | Nukleinsäureverstärkung mithilfe eines reversibel modifizierten oligonukleotids | |
| JP2006516891A5 (enExample) | ||
| Dunn et al. | DNA-dependent RNA polymerase from E. coli: Studies on the role of σ in chain initiation | |
| TW200506067A (en) | Method of detecting target nucleotide sequence, detection target structure to be used in embodying the method, process for producing the same and assay kit for detecting target nucleotide sequence | |
| ATE330031T1 (de) | Reversibel inhibierende sonden | |
| EP4403648A3 (en) | Methods and compositions for manipulating nucleic acids | |
| US11879152B2 (en) | Stoichiometric tuning of nucleic acid hybridization probes by auxiliary oligonucleotide species | |
| ATE455866T1 (de) | Verfahren zur unspezifischen amplifizierung nukleinsäuren mit niedriger komplexität | |
| Lahser et al. | A continuous nonradioactive assay for RNA-dependent RNA polymerase activity |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |