ATE41661T1 - 3-amino-2-oxo-azetidin-derivate enthaltend in 1- stellung einen stickstoffhaltigen heterocyclischen ring, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und die zwischenprodukte zu ihrer herstellung. - Google Patents

3-amino-2-oxo-azetidin-derivate enthaltend in 1- stellung einen stickstoffhaltigen heterocyclischen ring, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und die zwischenprodukte zu ihrer herstellung.

Info

Publication number
ATE41661T1
ATE41661T1 AT84400023T AT84400023T ATE41661T1 AT E41661 T1 ATE41661 T1 AT E41661T1 AT 84400023 T AT84400023 T AT 84400023T AT 84400023 T AT84400023 T AT 84400023T AT E41661 T1 ATE41661 T1 AT E41661T1
Authority
AT
Austria
Prior art keywords
radical
radicals
amino
alkyl
optionally substituted
Prior art date
Application number
AT84400023T
Other languages
English (en)
Inventor
Jean Georges Teutsch
Michel Klich
Jean-Francois Chantot
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Application granted granted Critical
Publication of ATE41661T1 publication Critical patent/ATE41661T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/16—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT84400023T 1983-01-10 1984-01-06 3-amino-2-oxo-azetidin-derivate enthaltend in 1- stellung einen stickstoffhaltigen heterocyclischen ring, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und die zwischenprodukte zu ihrer herstellung. ATE41661T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8300273A FR2539128A1 (fr) 1983-01-10 1983-01-10 Nouveaux derives de la 3-amino 2-oxoazetidine comportant en position 1 un radical heterocyclique azote, leur procede de preparation, leur application comme medicaments et les produits intermediaires necessaires a leur preparation
EP84400023A EP0114128B1 (de) 1983-01-10 1984-01-06 3-Amino-2-oxo-azetidin-Derivate enthaltend in 1-Stellung einen stickstoffhaltigen heterocyclischen Ring, Verfahren zu ihrer Herstellung, ihre Anwendung als Arzneimittel und die Zwischenprodukte zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
ATE41661T1 true ATE41661T1 (de) 1989-04-15

Family

ID=9284799

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84400023T ATE41661T1 (de) 1983-01-10 1984-01-06 3-amino-2-oxo-azetidin-derivate enthaltend in 1- stellung einen stickstoffhaltigen heterocyclischen ring, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und die zwischenprodukte zu ihrer herstellung.

Country Status (11)

Country Link
EP (1) EP0114128B1 (de)
JP (2) JPS59130862A (de)
AT (1) ATE41661T1 (de)
CA (1) CA1244034A (de)
DE (1) DE3477382D1 (de)
DK (1) DK164404C (de)
ES (1) ES528742A0 (de)
FR (1) FR2539128A1 (de)
GR (1) GR79459B (de)
IE (1) IE56521B1 (de)
PT (1) PT77939B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0649696B2 (ja) * 1983-07-04 1994-06-29 富山化学工業株式会社 新規なアゼチジノン誘導体およびその塩類
AU581180B2 (en) * 1983-08-26 1989-02-16 E.R. Squibb & Sons, Inc. 1-(1h-tetrazol-5-ylalkoxy)-2-azetidinones
JPH07108907B2 (ja) * 1984-06-25 1995-11-22 富山化学工業株式会社 新規なアゼチジノン誘導体またはその塩
JPH075592B2 (ja) * 1984-06-25 1995-01-25 富山化学工業株式会社 新規なアゼチジノン誘導体およびその塩
FR2582308B1 (fr) * 1985-05-22 1987-10-09 Roussel Uclaf Nouveaux derives de la 3-amino 2-oxoazetidine comportant en position 1 un radical tetrazolyle substitue par un radical organique clivable, leur procede de preparation et leur application comme medicaments
FR2585021B2 (fr) * 1985-07-18 1989-05-19 Roussel Uclaf Nouveaux derives de la 3-amino 2-oxoazetidinone comportant, en position 1, un radical heterocyclique azote, leur procede de preparation et leur application comme medicaments
US5006650A (en) * 1987-02-11 1991-04-09 The Upjohn Company Novel N-1 substituted beta-lactams as antibiotics
EP0344197B1 (de) * 1987-02-11 1991-08-14 The Upjohn Company Neue n-1 substituierte beta-lactame als antibiotika
AU600094B2 (en) * 1987-02-27 1990-08-02 Upjohn Company, The Antibiotic 2- azetidinones have pyrid -4- one 2-yl- carbonylamino-1-imidazolid-2-one-3-yl sulfonylaminocarbonyl groups at N-1
WO1989000569A1 (en) * 1987-07-22 1989-01-26 The Upjohn Company THERAPEUTICALLY USEFUL beta-LACTAMS
US5015737A (en) * 1987-07-22 1991-05-14 The Upjohn Company Therapeutically useful beta-lactams
CN103012316B (zh) * 2012-11-29 2015-03-25 浙江工业大学 N-4-甲基-1，2，3-噻二唑-4-酰基-n-取代1，3，4-噻二唑基硫脲衍生物及其制备和应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468874A (en) * 1967-04-10 1969-09-23 R & L Molecular Research Ltd 6 - tetrazolylacetamido penicillanic and 7-tetrazolylacetamido cephalosporanic acids
US4186131A (en) * 1977-04-21 1980-01-29 Mead Johnson & Company Phenyltetrazolyloxy propanolamines
DE2946432A1 (de) * 1979-11-17 1981-06-11 Bayer Ag, 5090 Leverkusen Tetrazolyloxycarbonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung als herbizide
WO1982001873A1 (en) * 1980-12-05 1982-06-10 Takeda Chemical Industries Ltd 1-sulfo-2-oxoazetidine derivatives and process for their preparation
JPS588060A (ja) * 1981-06-29 1983-01-18 イ−・ア−ル・スクイブ・アンド・サンズ・インコ−ポレイテツド アリ−ルチオアゼチジノンスルホン酸塩類

Also Published As

Publication number Publication date
JPS59130862A (ja) 1984-07-27
PT77939A (fr) 1984-02-01
CA1244034A (fr) 1988-11-01
DK164404C (da) 1992-11-09
JPH0678336B2 (ja) 1994-10-05
JPH03163076A (ja) 1991-07-15
PT77939B (fr) 1986-06-18
GR79459B (de) 1984-10-30
DK164404B (da) 1992-06-22
EP0114128B1 (de) 1989-03-22
DK7584D0 (da) 1984-01-09
FR2539128B1 (de) 1985-05-03
EP0114128A1 (de) 1984-07-25
ES8407046A1 (es) 1984-08-16
IE56521B1 (en) 1991-08-28
FR2539128A1 (fr) 1984-07-13
JPH0480912B2 (de) 1992-12-21
ES528742A0 (es) 1984-08-16
DK7584A (da) 1984-07-11
DE3477382D1 (en) 1989-04-27
IE840036L (en) 1984-07-10

Similar Documents

Publication Publication Date Title
ATE41661T1 (de) 3-amino-2-oxo-azetidin-derivate enthaltend in 1- stellung einen stickstoffhaltigen heterocyclischen ring, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und die zwischenprodukte zu ihrer herstellung.
ATE133683T1 (de) Erythromycinderivate, ihre verfahren zur herstellung, zwischenprodukte und ihre anwendung als medikamente
DE69325262D1 (de) Vinylen-azaindolderivate und verfahren zu ihrer herstellung
DE69515390D1 (de) Ureido-derivate von naphtalenphosphonsäure und verfahren zu ihrer herstellung
ATE128458T1 (de) Naphtylalkylamine, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
CA2143636A1 (en) Derivatives of valproic and 2-valproenoic acid amides and use as anticonvulsants
ATE167496T1 (de) Polyurethanharze, verfahren zu ihrer herstellung sowie ihre verwendung in wasserverdünnbaren überzugsmitteln
ATE210134T1 (de) Heterocyclisch substituierte imidazolidine, verfahren und zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zubereitungen
ATE170509T1 (de) Cyclische iminoderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE96431T1 (de) Sulfonamide, verfahren zu ihrer herstellung sowie diese verbindungen enthaltende arzneimittel.
DE69204662D1 (de) Poly-4-aminopyrrole-2-carboxamide derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel.
DE58904143D1 (de) Arylalkoxycumarine, verfahren zu ihrer herstellung und diese enthaltende therapeutische mittel.
ATE192143T1 (de) Substituierte 2,2-dimethyl-omega-phenoxysäure und ester, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE152707T1 (de) Neue naphthalin-amide und sulfonamide, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
ATE167187T1 (de) Chinuclidinestern, verfahren und zwischenprodukte zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
ATE160338T1 (de) Alpha aminosäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
ATE172976T1 (de) 3-aminochroman-spiroderivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen
DE59610410D1 (de) Triazolyloxybenzyl-alkoxyacrylsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung
ATE123776T1 (de) Aminoalkylchromone, verfahren zu ihrer herstellung und diese enthaltende zusammensetzungen.
ATA39088A (de) Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung
ATE87609T1 (de) (+)1-((3,4,5-trimethoxy)benzyloxymethyl>-1-phen l-n,n-dimethyl-n-propylamine, verfahren zu ihrer herstellung und ihre therapeutische verwendung.
DE3772936D1 (de) Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
DE69407042D1 (de) Psoralen-derivate, deren herstellung und verwendung als arzneimittel
ATE74600T1 (de) Derivate von 5-(2-(1-pyrrolidinyl)-aethoxy>-pcymen, verfahren zu ihrer herstellung und diese derivate enthaltende arzneimittel.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee