ATE414100T1 - Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen - Google Patents

Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen

Info

Publication number
ATE414100T1
ATE414100T1 AT02760458T AT02760458T ATE414100T1 AT E414100 T1 ATE414100 T1 AT E414100T1 AT 02760458 T AT02760458 T AT 02760458T AT 02760458 T AT02760458 T AT 02760458T AT E414100 T1 ATE414100 T1 AT E414100T1
Authority
AT
Austria
Prior art keywords
peyer
spot
cells
ligand against
targeted ligand
Prior art date
Application number
AT02760458T
Other languages
English (en)
Inventor
Daniel O'mahony
Imelda Lanbkin
Lisa Higgins
Original Assignee
Merrion Res Iii Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrion Res Iii Ltd filed Critical Merrion Res Iii Ltd
Application granted granted Critical
Publication of ATE414100T1 publication Critical patent/ATE414100T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02760458T 2001-07-02 2002-06-28 Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen ATE414100T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30259101P 2001-07-02 2001-07-02

Publications (1)

Publication Number Publication Date
ATE414100T1 true ATE414100T1 (de) 2008-11-15

Family

ID=23168408

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02760458T ATE414100T1 (de) 2001-07-02 2002-06-28 Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen

Country Status (8)

Country Link
US (3) US6916789B2 (de)
EP (1) EP1432729B1 (de)
JP (1) JP4383855B2 (de)
AT (1) ATE414100T1 (de)
AU (1) AU2002326070A1 (de)
CA (1) CA2451741C (de)
DE (1) DE60229867D1 (de)
WO (1) WO2003004517A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6521737B1 (en) * 1995-11-10 2003-02-18 Elan Corporation, Plc Peptides which enhance transport across tissues and methods of identifying and using the same
EP1432729B1 (de) * 2001-07-02 2008-11-12 Merrion Research III Limited Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen
JP5698426B2 (ja) * 2003-06-10 2015-04-08 ユニバーシティ オブ サスカチュワン キメラアデノウイルスキャプシドタンパク質
AU2012201102B2 (en) * 2004-06-23 2014-05-08 Ferguson, Ian Andrew Agents and methods for early diagnosis and monitoring of Alzheimer's disease and other neurological disorders
DE102005031755B9 (de) * 2005-07-01 2010-04-08 Technische Universität Dresden Salmonella spp. bindende Peptide, dafür kodierende Nukleinsäuren, deren Verwendungen und Verfahren und Kits zur Anreicherung, Immobilisierung und zum Nachweis von Salmonella spp.
WO2007137174A2 (en) * 2006-05-18 2007-11-29 The Ohio State University Research Foundation Compositions and methods for the detection of vulnerable plaque
RU2657749C2 (ru) 2012-09-21 2018-06-15 Интенсити Терапьютикс, Инк Способы лечения рака
JP6618892B2 (ja) 2013-04-23 2019-12-11 プレジデント アンド フェローズ オブ ハーバード カレッジ 細菌バイオフィルムの遺伝的リプログラミング
EP3280397A4 (de) * 2015-04-06 2018-08-22 President and Fellows of Harvard College Biosynthetische amyloid-basierte materialien mit funktionellen proteinsequenzen
WO2017201428A1 (en) 2016-05-19 2017-11-23 President And Fellows Of Harvard College Methods of making gels and film using curli nanofibers
WO2018081355A1 (en) 2016-10-26 2018-05-03 Chen, Chung-Chin Fusion polypeptide for immuno-enhancement and method for enhancing stimulation of immune response using the same

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR940010862B1 (ko) * 1985-02-05 1994-11-18 씨네겐 바이오로지칼즈, 인코포레이티드 유용한 메탈로프로테이나제 억제제 씨퀀스 재조합 벡터계의 제조를 위한 dna 재조합 방법
IL84167A (en) * 1986-10-24 1991-04-15 Southern Res Inst Oral delivery of bioactive agents to and through the peyer's patch by use of microencapsulation
US5254342A (en) 1991-09-30 1993-10-19 University Of Southern California Compositions and methods for enhanced transepithelial and transendothelial transport or active agents
GB9201139D0 (en) * 1992-01-20 1992-03-11 Connaught Lab Synthetic peptides for a rubella vaccine
AU3937693A (en) 1992-04-10 1993-11-18 Brigham And Women's Hospital Methods and compositions for oral delivery of therapeutic agents
US5534496A (en) 1992-07-07 1996-07-09 University Of Southern California Methods and compositions to enhance epithelial drug transport
EP0750630A4 (de) * 1994-03-11 1998-01-07 Ariad Pharma Inc Methode und materialien zur identifizierung von inhibitoren der molekularen interaktionen, welche durch die sh3 domänen vermittelt werden
US5831008A (en) * 1994-08-18 1998-11-03 La Jolla Cancer Research Foundation Retinoblastoma protein-interacting zinc finger proteins
US6030613A (en) 1995-01-17 2000-02-29 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of therapeutics
US6086875A (en) 1995-01-17 2000-07-11 The Brigham And Women's Hospital, Inc. Receptor specific transepithelial transport of immunogens
DE69629385T2 (de) * 1995-11-10 2004-06-09 Elan Corp. Plc Peptide, die den transport über gewebe erhöhen und verfahren zu ihrer identifizierung und verwendung
IE80466B1 (en) 1995-11-10 1998-07-29 Elan Corp Plc Peptides which enhance transport across tissues and methods of identifying and using the same
US6261787B1 (en) 1996-06-03 2001-07-17 Case Western Reserve University Bifunctional molecules for delivery of therapeutics
US6060082A (en) 1997-04-18 2000-05-09 Massachusetts Institute Of Technology Polymerized liposomes targeted to M cells and useful for oral or mucosal drug delivery
JP4129298B2 (ja) * 1997-05-15 2008-08-06 サイトジェン コーポレーション 胃腸管（ｇｉｔ）輸送受容体に結合するランダムペプチド、及び関連した方法
EP1230267B1 (de) * 1999-09-27 2006-03-29 Elan Corporation Membrantranslokierendes peptid als wirkstofftransportsystem
JP2001245675A (ja) * 1999-12-28 2001-09-11 Kyogo Ito 腫瘍抗原
CN1323825A (zh) * 2000-05-16 2001-11-28 上海博德基因开发有限公司 一种新的多肽——人网格蛋白轻链9和编码这种多肽的多核苷酸
AU2002254161A1 (en) * 2001-03-12 2002-09-24 Montana State University-Bozeman M cell directed vaccines
EP1419252A2 (de) * 2001-04-04 2004-05-19 Merrion Research I Limited Genetische analyse der peyer'schen plaques und m zellen und verfahren und zusammensetzungen zur targeting der peyer'schen plaques und m zellen
EP1432729B1 (de) * 2001-07-02 2008-11-12 Merrion Research III Limited Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen

Also Published As

Publication number Publication date
JP4383855B2 (ja) 2009-12-16
EP1432729A2 (de) 2004-06-30
WO2003004517A2 (en) 2003-01-16
US20100016549A1 (en) 2010-01-21
EP1432729B1 (de) 2008-11-12
WO2003004517A3 (en) 2004-04-29
US20030096354A1 (en) 2003-05-22
US7485321B2 (en) 2009-02-03
JP2005503782A (ja) 2005-02-10
CA2451741A1 (en) 2003-01-16
US6916789B2 (en) 2005-07-12
US20050227924A1 (en) 2005-10-13
CA2451741C (en) 2014-02-18
AU2002326070A1 (en) 2003-01-21
DE60229867D1 (de) 2008-12-24

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