ATE404524T1 - Neuartiges verfahren zur herstellung bicyclischer amino-alkohole - Google Patents

Neuartiges verfahren zur herstellung bicyclischer amino-alkohole

Info

Publication number
ATE404524T1
ATE404524T1 AT00939160T AT00939160T ATE404524T1 AT E404524 T1 ATE404524 T1 AT E404524T1 AT 00939160 T AT00939160 T AT 00939160T AT 00939160 T AT00939160 T AT 00939160T AT E404524 T1 ATE404524 T1 AT E404524T1
Authority
AT
Austria
Prior art keywords
novel process
amino alcohols
bicyclic amino
producing bicyclic
producing
Prior art date
Application number
AT00939160T
Other languages
English (en)
Inventor
Tsunetoshi Honma
Yoshiharu Hiramatsu
Susumu Mitsumori
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi & Co filed Critical Shionogi & Co
Application granted granted Critical
Publication of ATE404524T1 publication Critical patent/ATE404524T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/188—Preparation; Treatments not provided for in C07F7/20 by reactions involving the formation of Si-O linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/02—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions involving the formation of amino groups from compounds containing hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/42—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having amino groups or hydroxy groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00—Preparation of carboxylic acid esters
    • C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D333/70—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/42—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing seven carbon atoms
AT00939160T 1999-07-02 2000-06-26 Neuartiges verfahren zur herstellung bicyclischer amino-alkohole ATE404524T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18867499 1999-07-02

Publications (1)

Publication Number Publication Date
ATE404524T1 true ATE404524T1 (de) 2008-08-15

Family

ID=16227874

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00939160T ATE404524T1 (de) 1999-07-02 2000-06-26 Neuartiges verfahren zur herstellung bicyclischer amino-alkohole

Country Status (7)

Country Link
US (2) US6723857B1 (de)
EP (2) EP1808427A3 (de)
JP (1) JP3730170B2 (de)
AT (1) ATE404524T1 (de)
AU (1) AU5430100A (de)
DE (1) DE60039876D1 (de)
WO (1) WO2001002334A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2898893A1 (fr) * 2006-03-27 2007-09-28 Ppg Sipsy Soc Par Actions Simp Procede d'alkylation diastereoselective d'ether d'oxime du compose nopinone et nouveaux intermediaires pour la synthese de derives 2-amino-nopinone diastereospecifiques substitues sur le carbone 3

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06239917A (ja) 1993-02-19 1994-08-30 Mitsubishi Petrochem Co Ltd α‐オレフィン重合用触媒成分およびそれを用いたα‐オレフィン重合体の製造法
BR9714016A (pt) 1996-12-13 2000-02-29 Shionogi & Co Derivados de benzotiofenocarboxamida e antagonistas a pgd2, que compreendem os mesmos
PL197331B1 (pl) 1998-03-31 2008-03-31 Shionogi & Co Sposób wytwarzania pochodnych kwasów 5-hydroksybenzo [b] -tiofeno-3-karboksylowych
EP1069123B1 (de) * 1998-03-31 2004-11-10 Shionogi & Co., Ltd. Verfahren zur herstellung von benzothiophencarbonsäureamid-derivaten
CA2333868A1 (en) * 1998-06-03 1999-12-09 Shionogi & Co., Ltd. Pharmaceutical compositions for the treatment of itching comprising pgd2 receptors antagonists

Also Published As

Publication number Publication date
EP1808427A2 (de) 2007-07-18
DE60039876D1 (de) 2008-09-25
US20040171882A1 (en) 2004-09-02
EP1193243A4 (de) 2004-08-11
EP1193243B1 (de) 2008-08-13
EP1808427A3 (de) 2008-06-25
AU5430100A (en) 2001-01-22
WO2001002334A1 (fr) 2001-01-11
JP3730170B2 (ja) 2005-12-21
US6723857B1 (en) 2004-04-20
US7214832B2 (en) 2007-05-08
EP1193243A1 (de) 2002-04-03

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