ATE398136T1 - Therapeutika und diagnostika, die die zelluläre ansprechbarkeit auf cytokine regulieren - Google Patents

Therapeutika und diagnostika, die die zelluläre ansprechbarkeit auf cytokine regulieren

Info

Publication number
ATE398136T1
ATE398136T1 AT97909070T AT97909070T ATE398136T1 AT E398136 T1 ATE398136 T1 AT E398136T1 AT 97909070 T AT97909070 T AT 97909070T AT 97909070 T AT97909070 T AT 97909070T AT E398136 T1 ATE398136 T1 AT E398136T1
Authority
AT
Austria
Prior art keywords
therapeutic
cytokine
diagnostics
signal transduction
present
Prior art date
Application number
AT97909070T
Other languages
English (en)
Inventor
Douglas Hilton
Warren Alexander
Elizabeth Viney
Tracy Willson
Rachael Richardson
Robyn Starr
Sandra Nicholson
Donald Metcalf
Nicos Nicola
Original Assignee
Inst Medical W & E Hall
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPO3384A external-priority patent/AUPO338496A0/en
Priority claimed from AUPO5117A external-priority patent/AUPO511797A0/en
Application filed by Inst Medical W & E Hall filed Critical Inst Medical W & E Hall
Application granted granted Critical
Publication of ATE398136T1 publication Critical patent/ATE398136T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2/00—Peptides of undefined number of amino acids; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT97909070T 1996-11-01 1997-10-31 Therapeutika und diagnostika, die die zelluläre ansprechbarkeit auf cytokine regulieren ATE398136T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AUPO3384A AUPO338496A0 (en) 1996-11-01 1996-11-01 Therapeutic and diagnostic agents
AUPO5117A AUPO511797A0 (en) 1997-02-14 1997-02-14 Therapeutic and diagnostic agents-II

Publications (1)

Publication Number Publication Date
ATE398136T1 true ATE398136T1 (de) 2008-07-15

Family

ID=25645307

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97909070T ATE398136T1 (de) 1996-11-01 1997-10-31 Therapeutika und diagnostika, die die zelluläre ansprechbarkeit auf cytokine regulieren

Country Status (13)

Country Link
US (1) US20080166730A1 (de)
EP (2) EP1975234A2 (de)
JP (2) JP2001502183A (de)
KR (2) KR100719080B1 (de)
CN (2) CN1253565A (de)
AT (1) ATE398136T1 (de)
CA (1) CA2270171A1 (de)
DE (1) DE69738767D1 (de)
DK (1) DK0948522T3 (de)
ES (1) ES2308785T3 (de)
GB (1) GB2331753A (de)
NO (1) NO992116L (de)
WO (1) WO1998020023A1 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6495518B1 (en) 1994-06-13 2002-12-17 Vanderbilt University Method for importing biologically active molecules into cells
CA2230986A1 (en) * 1997-05-07 1998-11-07 Smithkline Beecham Corporation Epo primary response gene 1, eprg1
AU8484698A (en) * 1997-07-18 1999-02-10 Schering Corporation Suppressors of cytokine signaling socs16; related reagents
JP2001508312A (ja) * 1997-11-03 2001-06-26 インサイト・ファーマスーティカルズ・インコーポレイテッド サイトカインシグナリングのサプレッサ
AU2668699A (en) * 1998-02-11 1999-08-30 Beth Israel Deaconess Medical Center Methods and compositions for modulating leptin activity
EP0953636A3 (de) * 1998-03-23 2000-03-29 Smithkline Beecham Plc Cytokin-Signal Regulator
EP1064368A1 (de) * 1998-03-23 2001-01-03 Smithkline Beecham Plc Suppressoren des cytokinsignals
US6620382B1 (en) * 1998-05-22 2003-09-16 Biopheresis Technologies, Llc. Method and compositions for treatment of cancers
WO1999061614A2 (en) * 1998-05-28 1999-12-02 Incyte Pharmaceuticals, Inc. Human socs proteins
SE9803398D0 (sv) * 1998-10-06 1998-10-06 Sahltech Ab "New use"
WO2000037636A1 (en) * 1998-12-21 2000-06-29 The Walter And Eliza Hall Institute Of Medical Research Socs-box containing peptides
WO2000063357A2 (en) * 1999-04-20 2000-10-26 Beth Israel Deaconess Medical Center Methods and compositions for modulating ciliary neurotrophic factor activity
US6541244B1 (en) 1999-06-07 2003-04-01 Cedars-Sinai Medical Center Suppressor of cytokine signaling (SOCS)-3 promoter and methods for its use in genetic therapy in humans
WO2001035732A1 (en) * 1999-11-16 2001-05-25 The Walter And Eliza Hall Institute Of Medical Research An animal model for studying hormone signalling and method of modulating the signalling
AU784277B2 (en) * 1999-11-16 2006-03-02 Walter And Eliza Hall Institute Of Medical Research, The An animal model for studying hormone signalling and method of modulating the signalling
WO2001079555A2 (en) * 2000-04-14 2001-10-25 Millennium Pharmaceuticals, Inc. Roles of jak/stat family members in tolerance induction
EP1330156A4 (de) * 2000-10-09 2006-09-13 Amrad Operations Pty Ltd Modulation der cytokin- oder hormonsignalleitung bei einem tier, wobei die expression der socs-sequenz bei diesem tier hinaufreguliert wird
GB2373502A (en) * 2000-11-08 2002-09-25 Smithkline Beecham Corp Suppressor of cytokine signalling 4 (SOCS4)
EP1341913A2 (de) * 2000-12-14 2003-09-10 PHARMACIA & UPJOHN COMPANY Socs (suppressor der cytokin signalierung)
AUPR556601A0 (en) * 2001-06-08 2001-07-12 Ludwig Institute For Cancer Research Therapeutic and diagnostic molecules - II
JPWO2003072778A1 (ja) * 2002-02-27 2005-06-23 株式会社ジェノックス創薬研究所 アレルギー性疾患の検査方法
US8420096B2 (en) 2004-03-04 2013-04-16 Vanderbilt University Cell-penetrating SOCS polypeptides that inhibit cytokine-induced signaling
JP2005312364A (ja) * 2004-04-28 2005-11-10 Mitsuo Itakura 糖尿病治療剤スクリーニング方法
WO2006088010A1 (ja) * 2005-02-15 2006-08-24 Toagosei Co., Ltd. 抗菌ペプチド及びその利用
EP2427210A4 (de) * 2009-05-08 2012-10-24 Inst Medical W & E Hall Modulation der bindung von induzierbarer stickoxidsynthase (inos) an spry-domain-haltige socs-box-peptide (ssb)
KR101124622B1 (ko) * 2009-10-26 2012-03-19 한국생명공학연구원 Ｓｏｃｓ２ 유전자의 발현을 조절하여 자연 살해 세포를 활성화시키는 방법
JP2019505498A (ja) * 2015-12-16 2019-02-28 ザ・ウォルター・アンド・エリザ・ホール・インスティテュート・オブ・メディカル・リサーチ Ｎｋ細胞におけるサイトカイン誘導性ｓｈ２タンパク質の阻害

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4420782C1 (de) * 1994-06-15 1995-08-17 Fluegge Ulf Ingo Prof Dr DNA-Sequenz, kodierend einen 2-Oxoglutarat/Malat-Translokator, Plasmide, Bakterien, Hefen und Pflanzen enthaltend diesen Transporter
US4018653A (en) 1971-10-29 1977-04-19 U.S. Packaging Corporation Instrument for the detection of Neisseria gonorrhoeae without culture
US4016043A (en) 1975-09-04 1977-04-05 Akzona Incorporated Enzymatic immunological method for the determination of antigens and antibodies
US4424279A (en) 1982-08-12 1984-01-03 Quidel Rapid plunger immunoassay method and apparatus
JPH07291996A (ja) * 1994-03-01 1995-11-07 Yuu Honshiyo ヒトにおけるプログラムされた細胞死に関連したポリペプチド、それをコードするｄｎａ、そのｄｎａからなるベクター、そのベクターで形質転換された宿主細胞、そのポリペプチドの抗体、およびそのポリペプチドまたはその抗体を含有する薬学的組成物
EP0832117A1 (de) * 1995-06-05 1998-04-01 The Trustees Of Dartmouth College Genexpression, stimuliert durch liganden
AU4723797A (en) * 1997-01-10 1998-08-03 Tadamitsu Kishimoto Novel stat function-regulatory protein
AU8484698A (en) * 1997-07-18 1999-02-10 Schering Corporation Suppressors of cytokine signaling socs16; related reagents

Also Published As

Publication number Publication date
NO992116L (no) 1999-06-29
CN1253565A (zh) 2000-05-17
ES2308785T3 (es) 2008-12-01
EP1975234A2 (de) 2008-10-01
EP0948522B1 (de) 2008-06-11
EP0948522A4 (de) 2001-09-19
KR100719080B1 (ko) 2007-05-16
CA2270171A1 (en) 1998-05-14
US20080166730A1 (en) 2008-07-10
WO1998020023A1 (en) 1998-05-14
CN101280305A (zh) 2008-10-08
GB2331753A (en) 1999-06-02
GB9905020D0 (en) 1999-04-28
KR20000053017A (ko) 2000-08-25
DK0948522T3 (da) 2008-09-22
JP2001502183A (ja) 2001-02-20
EP0948522A1 (de) 1999-10-13
JP2009060903A (ja) 2009-03-26
NO992116D0 (no) 1999-04-30
KR20060053007A (ko) 2006-05-19
DE69738767D1 (de) 2008-07-24

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Legal Events

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