ATE397095T1 - Verfahren zur manipulation von nukleinsäuren - Google Patents

Verfahren zur manipulation von nukleinsäuren

Info

Publication number
ATE397095T1
ATE397095T1 AT02764202T AT02764202T ATE397095T1 AT E397095 T1 ATE397095 T1 AT E397095T1 AT 02764202 T AT02764202 T AT 02764202T AT 02764202 T AT02764202 T AT 02764202T AT E397095 T1 ATE397095 T1 AT E397095T1
Authority
AT
Austria
Prior art keywords
polymerase
nucleic acid
recombination
protein
bacteriophage
Prior art date
Application number
AT02764202T
Other languages
English (en)
Inventor
Stephen Benkovic
Frank Salinas
Original Assignee
Penn State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Penn State Res Found filed Critical Penn State Res Found
Application granted granted Critical
Publication of ATE397095T1 publication Critical patent/ATE397095T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT02764202T 2001-04-20 2002-04-19 Verfahren zur manipulation von nukleinsäuren ATE397095T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28512701P 2001-04-20 2001-04-20

Publications (1)

Publication Number Publication Date
ATE397095T1 true ATE397095T1 (de) 2008-06-15

Family

ID=23092836

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02764202T ATE397095T1 (de) 2001-04-20 2002-04-19 Verfahren zur manipulation von nukleinsäuren

Country Status (8)

Country Link
US (21) US6929915B2 (de)
EP (1) EP1386006B1 (de)
AT (1) ATE397095T1 (de)
AU (1) AU2002307371B2 (de)
CA (1) CA2444649C (de)
DE (1) DE60226856D1 (de)
ES (1) ES2305289T3 (de)
WO (1) WO2002086167A1 (de)

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US6929915B2 (en) 2001-04-20 2005-08-16 The Penn State Research Foundation Methods for nucleic acid manipulation
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
EP1992706B1 (de) * 2002-02-21 2014-11-19 Alere San Diego, Inc. Rekombinase-Polymerase-Verstärkung
DE60324810D1 (de) * 2002-09-20 2009-01-02 New England Biolabs Inc HELICASE-ABHuNGIGE AMPLIFIKATION VON NUKLEINSUREN
EP3540073B1 (de) * 2004-06-01 2021-08-25 Abbott Diagnostics Scarborough, Inc. Rekombinase-polymerase-amplifikation
DK2088193T3 (da) * 2004-11-24 2011-02-28 Anaeropharma Science Inc Ny shuttle-vektor
WO2007096702A2 (en) 2005-07-25 2007-08-30 Asm Scientific, Inc. Methods for multiplexing recombinase polymerase amplification
US20090061413A1 (en) * 2006-02-27 2009-03-05 Salinas Frank G Isothermal screening of hiv-1 related nucleic acids
US20090170064A1 (en) * 2006-02-27 2009-07-02 Frank G Salinas Isothermal screening of human papillomavirus related nucleic acids
US20070202522A1 (en) * 2006-02-27 2007-08-30 Salinas Frank G Isothermal screening of tumor cell related nucleic acids
US20080003600A1 (en) * 2006-02-27 2008-01-03 Salinas Frank G Isothermal screening of breast cancer related nucleic acid
US20080220421A1 (en) * 2006-02-27 2008-09-11 Salinas Frank G Isothermal screening for nucleic acids associated with diseases and conditions of the gi tract
EP2426221B1 (de) 2006-05-04 2016-06-22 Alere San Diego, Inc. Rekombinase-Polymerase-Amplifikation
US9689031B2 (en) 2007-07-14 2017-06-27 Ionian Technologies, Inc. Nicking and extension amplification reaction for the exponential amplification of nucleic acids
US20090215050A1 (en) * 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
US9334531B2 (en) 2010-12-17 2016-05-10 Life Technologies Corporation Nucleic acid amplification
US9309557B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Nucleic acid amplification
US9309566B2 (en) 2010-12-17 2016-04-12 Life Technologies Corporation Methods, compositions, systems, apparatuses and kits for nucleic acid amplification
US9469867B2 (en) * 2009-05-20 2016-10-18 Alere San Diego, Inc. DNA glycosylase/lyase and AP endonuclease substrates
EP3360974A1 (de) 2009-06-05 2018-08-15 Alere San Diego, Inc. Reagentien zur rekombinase polymerase amplifikation
CN103370425B (zh) 2010-12-17 2019-03-19 生命技术公司 用于核酸扩增的方法、组合物、系统、仪器和试剂盒
EP3202918B1 (de) 2011-04-07 2021-10-20 Abbott Diagnostics Scarborough, Inc. Überwachung von rekombinase-polymerase-verstärkungsmischungen
US9012022B2 (en) 2012-06-08 2015-04-21 Illumina, Inc. Polymer coatings
US8895249B2 (en) 2012-06-15 2014-11-25 Illumina, Inc. Kinetic exclusion amplification of nucleic acid libraries
CN102816756B (zh) * 2012-09-07 2014-04-16 江苏奇天基因生物科技有限公司 等温核酸扩增反应试剂及等温核酸扩增方法
US9512422B2 (en) 2013-02-26 2016-12-06 Illumina, Inc. Gel patterned surfaces
AU2014248813B2 (en) 2013-03-11 2016-05-19 Cue Health Inc. Systems and methods for detection and quantification of analytes
US9623409B2 (en) 2013-03-11 2017-04-18 Cue Inc. Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes
US10545161B2 (en) 2013-03-11 2020-01-28 Cue Health Inc. Systems and methods for detection and quantification of analytes
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
EP3325153B1 (de) 2015-07-17 2020-03-18 Cue Health Inc. Kartusche zur probenanalyse
WO2018140540A1 (en) 2017-01-25 2018-08-02 Cue Health Inc. Systems and methods for enhanced detection and quantification of analytes

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JPS63109800A (ja) * 1986-10-27 1988-05-14 Rikagaku Kenkyusho Ｄｎａ塩基配列決定法
DE69220084T2 (de) * 1990-05-07 1997-09-11 Daikin Ind Ltd Diagnostische Anwendungen der Bildung von doppelten D-Loops.
US5223414A (en) * 1990-05-07 1993-06-29 Sri International Process for nucleic acid hybridization and amplification
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WO1994003624A1 (en) 1992-08-04 1994-02-17 Auerbach Jeffrey I Methods for the isothermal amplification of nucleic acid molecules
RU2048522C1 (ru) 1992-10-14 1995-11-20 Институт белка РАН Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления
US6001568A (en) 1992-10-26 1999-12-14 Institut Belka Solid medium for amplification and expression of nucleic acids as colonies
US5780296A (en) * 1995-01-17 1998-07-14 Thomas Jefferson University Compositions and methods to promote homologous recombination in eukaryotic cells and organisms
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CA2305449A1 (en) 1997-10-10 1999-04-22 President & Fellows Of Harvard College Replica amplification of nucleic acid arrays
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US6531302B1 (en) 1999-04-12 2003-03-11 Nanogen/Becton Dickinson Partnership Anchored strand displacement amplification on an electronically addressable microchip
US7332308B1 (en) 1999-05-21 2008-02-19 The Penn State Research Foundation Incrementally truncated nucleic acids and methods of making same
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IL153504A0 (en) 2001-03-09 2003-07-06 Nugen Technologies Inc Methods and compositions for amplification of rna sequences
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JP4091304B2 (ja) * 2002-01-07 2008-05-28 セイコーインスツル株式会社 半導体集積回路の製造方法及び半導体集積回路
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US7399590B2 (en) * 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification

Also Published As

Publication number Publication date
US20130137145A1 (en) 2013-05-30
US8765374B2 (en) 2014-07-01
US20100279358A1 (en) 2010-11-04
US20130330775A2 (en) 2013-12-12
US20100279357A1 (en) 2010-11-04
US20160237475A1 (en) 2016-08-18
ES2305289T3 (es) 2008-11-01
US20130143274A1 (en) 2013-06-06
US9322057B2 (en) 2016-04-26
US10017803B2 (en) 2018-07-10
US9322059B2 (en) 2016-04-26
US7723031B2 (en) 2010-05-25
US8361718B2 (en) 2013-01-29
US8759000B2 (en) 2014-06-24
US6929915B2 (en) 2005-08-16
US20130137146A1 (en) 2013-05-30
US20100279379A1 (en) 2010-11-04
US7906279B2 (en) 2011-03-15
US20060292582A1 (en) 2006-12-28
US20030143525A1 (en) 2003-07-31
US20140308673A1 (en) 2014-10-16
US20180265906A1 (en) 2018-09-20
US20140234910A1 (en) 2014-08-21
WO2002086167A1 (en) 2002-10-31
US9322058B2 (en) 2016-04-26
US20140178941A1 (en) 2014-06-26
US20100285482A1 (en) 2010-11-11
CA2444649A1 (en) 2002-10-31
US8637243B2 (en) 2014-01-28
US20100285538A1 (en) 2010-11-11
US20100285481A1 (en) 2010-11-11
US20060024709A1 (en) 2006-02-02
US8673561B2 (en) 2014-03-18
US9562250B2 (en) 2017-02-07
US20160265015A1 (en) 2016-09-15
DE60226856D1 (de) 2008-07-10
US20130323792A2 (en) 2013-12-05
US20040171060A1 (en) 2004-09-02
US8241851B2 (en) 2012-08-14
EP1386006A1 (de) 2004-02-04
US20130330776A2 (en) 2013-12-12
EP1386006B1 (de) 2008-05-28
US20130143273A1 (en) 2013-06-06
US8389216B2 (en) 2013-03-05
EP1386006A4 (de) 2004-09-15
US8129116B2 (en) 2012-03-06
CA2444649C (en) 2012-10-02
AU2002307371B2 (en) 2008-04-03
US20140356936A1 (en) 2014-12-04
US8124342B2 (en) 2012-02-28
US8137913B2 (en) 2012-03-20
US10000781B2 (en) 2018-06-19

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