ATE397095T1 - Verfahren zur manipulation von nukleinsäuren - Google Patents
Verfahren zur manipulation von nukleinsäurenInfo
- Publication number
- ATE397095T1 ATE397095T1 AT02764202T AT02764202T ATE397095T1 AT E397095 T1 ATE397095 T1 AT E397095T1 AT 02764202 T AT02764202 T AT 02764202T AT 02764202 T AT02764202 T AT 02764202T AT E397095 T1 ATE397095 T1 AT E397095T1
- Authority
- AT
- Austria
- Prior art keywords
- polymerase
- nucleic acid
- recombination
- protein
- bacteriophage
- Prior art date
Links
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 230000006798 recombination Effects 0.000 abstract 4
- 238000005215 recombination Methods 0.000 abstract 4
- 108010025076 Holoenzymes Proteins 0.000 abstract 2
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 101000749445 Enterobacteria phage T4 Recombination and repair protein Proteins 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 230000003321 amplification Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000003199 nucleic acid amplification method Methods 0.000 abstract 1
- 230000010076 replication Effects 0.000 abstract 1
- 230000003362 replicative effect Effects 0.000 abstract 1
- 241000894007 species Species 0.000 abstract 1
- 241001515965 unidentified phage Species 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/102—Mutagenizing nucleic acids
- C12N15/1027—Mutagenizing nucleic acids by DNA shuffling, e.g. RSR, STEP, RPR
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6844—Nucleic acid amplification reactions
- C12Q1/686—Polymerase chain reaction [PCR]
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Plant Pathology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28512701P | 2001-04-20 | 2001-04-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE397095T1 true ATE397095T1 (de) | 2008-06-15 |
Family
ID=23092836
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02764202T ATE397095T1 (de) | 2001-04-20 | 2002-04-19 | Verfahren zur manipulation von nukleinsäuren |
Country Status (8)
| Country | Link |
|---|---|
| US (21) | US6929915B2 (de) |
| EP (1) | EP1386006B1 (de) |
| AT (1) | ATE397095T1 (de) |
| AU (1) | AU2002307371B2 (de) |
| CA (1) | CA2444649C (de) |
| DE (1) | DE60226856D1 (de) |
| ES (1) | ES2305289T3 (de) |
| WO (1) | WO2002086167A1 (de) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE397095T1 (de) | 2001-04-20 | 2008-06-15 | Penn State Res Found | Verfahren zur manipulation von nukleinsäuren |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| DE60322044D1 (de) | 2002-02-21 | 2008-08-21 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
| EP1539979B1 (de) * | 2002-09-20 | 2008-11-19 | New England Biolabs, Inc. | HELICASE-ABHûNGIGE AMPLIFIKATION VON NUKLEINSUREN |
| JP5026958B2 (ja) * | 2004-06-01 | 2012-09-19 | アリーア サン ディエゴ， インコーポレイテッド | リコンビナーゼポリメラーゼ増幅 |
| WO2006057289A1 (ja) * | 2004-11-24 | 2006-06-01 | Anaeropharma Science Inc. | 新規シャトルベクター |
| JP5027126B2 (ja) | 2005-07-25 | 2012-09-19 | アリーア サン ディエゴ， インコーポレイテッド | リコンビナーゼポリメラーゼ増幅を多重化するための方法 |
| US20080220421A1 (en) * | 2006-02-27 | 2008-09-11 | Salinas Frank G | Isothermal screening for nucleic acids associated with diseases and conditions of the gi tract |
| US20090061413A1 (en) * | 2006-02-27 | 2009-03-05 | Salinas Frank G | Isothermal screening of hiv-1 related nucleic acids |
| US20080003600A1 (en) * | 2006-02-27 | 2008-01-03 | Salinas Frank G | Isothermal screening of breast cancer related nucleic acid |
| US20070202522A1 (en) * | 2006-02-27 | 2007-08-30 | Salinas Frank G | Isothermal screening of tumor cell related nucleic acids |
| US20090170064A1 (en) * | 2006-02-27 | 2009-07-02 | Frank G Salinas | Isothermal screening of human papillomavirus related nucleic acids |
| JP2009535053A (ja) | 2006-05-04 | 2009-10-01 | エーエスエム サイエンティフィック， インコーポレイテッド | レコンビナーゼポリメラーゼ増幅 |
| US9689031B2 (en) | 2007-07-14 | 2017-06-27 | Ionian Technologies, Inc. | Nicking and extension amplification reaction for the exponential amplification of nucleic acids |
| US20090215050A1 (en) * | 2008-02-22 | 2009-08-27 | Robert Delmar Jenison | Systems and methods for point-of-care amplification and detection of polynucleotides |
| US9334531B2 (en) | 2010-12-17 | 2016-05-10 | Life Technologies Corporation | Nucleic acid amplification |
| US9309566B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Methods, compositions, systems, apparatuses and kits for nucleic acid amplification |
| US20120156728A1 (en) | 2010-12-17 | 2012-06-21 | Life Technologies Corporation | Clonal amplification of nucleic acid on solid surface with template walking |
| US9309557B2 (en) | 2010-12-17 | 2016-04-12 | Life Technologies Corporation | Nucleic acid amplification |
| JP5847076B2 (ja) | 2009-05-20 | 2016-01-20 | バイオサイト インコーポレイテッド | Ｄｎａグリコシラーゼ／リアーゼおよびａｐエンドヌクレアーゼ基質 |
| EP3360974B1 (de) | 2009-06-05 | 2025-04-09 | Abbott Diagnostics Scarborough, Inc. | Reagentien zur rekombinase polymerase amplifikation |
| US8809021B2 (en) | 2011-04-07 | 2014-08-19 | Alere San Diego Inc. | Monitoring recombinase polymerase amplification mixtures |
| US9012022B2 (en) | 2012-06-08 | 2015-04-21 | Illumina, Inc. | Polymer coatings |
| US8895249B2 (en) | 2012-06-15 | 2014-11-25 | Illumina, Inc. | Kinetic exclusion amplification of nucleic acid libraries |
| CN102816756B (zh) * | 2012-09-07 | 2014-04-16 | 江苏奇天基因生物科技有限公司 | 等温核酸扩增反应试剂及等温核酸扩增方法 |
| US9512422B2 (en) | 2013-02-26 | 2016-12-06 | Illumina, Inc. | Gel patterned surfaces |
| US10545161B2 (en) | 2013-03-11 | 2020-01-28 | Cue Health Inc. | Systems and methods for detection and quantification of analytes |
| US9623409B2 (en) | 2013-03-11 | 2017-04-18 | Cue Inc. | Cartridges, kits, and methods for enhanced mixing for detection and quantification of analytes |
| CN112782393B (zh) | 2013-03-11 | 2024-11-19 | 克忧健康公司 | 用于检测和量化分析物的系统和方法 |
| USD745423S1 (en) | 2014-05-12 | 2015-12-15 | Cue Inc. | Automated analyzer test cartridge and sample collection device for analyte detection |
| JP6824953B2 (ja) | 2015-07-17 | 2021-02-03 | キュー ヘルス インコーポレイテッド | 検体の向上された検出および量子化のためのシステムおよび方法 |
| WO2018140540A1 (en) | 2017-01-25 | 2018-08-02 | Cue Health Inc. | Systems and methods for enhanced detection and quantification of analytes |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63109800A (ja) * | 1986-10-27 | 1988-05-14 | Rikagaku Kenkyusho | Ｄｎａ塩基配列決定法 |
| JP2745816B2 (ja) * | 1990-05-07 | 1998-04-28 | ダイキン工業株式会社 | ダブルｄループ形成の診断応用 |
| US5223414A (en) * | 1990-05-07 | 1993-06-29 | Sri International | Process for nucleic acid hybridization and amplification |
| WO1993015115A1 (en) * | 1992-01-24 | 1993-08-05 | Cornell Research Foundation, Inc. | E. coli dna polymerase iii holoenzyme and subunits |
| WO1994003624A1 (en) | 1992-08-04 | 1994-02-17 | Auerbach Jeffrey I | Methods for the isothermal amplification of nucleic acid molecules |
| RU2048522C1 (ru) | 1992-10-14 | 1995-11-20 | Институт белка РАН | Способ размножения нуклеиновых кислот, способ их экспрессии и среда для их осуществления |
| US6001568A (en) | 1992-10-26 | 1999-12-14 | Institut Belka | Solid medium for amplification and expression of nucleic acids as colonies |
| US5780296A (en) * | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
| AT402203B (de) | 1995-06-13 | 1997-03-25 | Himmler Gottfried Dipl Ing Dr | Verfahren zur transkriptionsfreien amplifizierung von nucleinsäuren |
| US5670325A (en) | 1996-08-14 | 1997-09-23 | Exact Laboratories, Inc. | Method for the detection of clonal populations of transformed cells in a genomically heterogeneous cellular sample |
| WO1997039150A1 (en) * | 1996-04-15 | 1997-10-23 | University Of Southern California | Synthesis of fluorophore-labeled dna |
| US5928870A (en) | 1997-06-16 | 1999-07-27 | Exact Laboratories, Inc. | Methods for the detection of loss of heterozygosity |
| WO1998008975A1 (en) | 1996-08-29 | 1998-03-05 | Daikin Industries, Ltd. | Methods for targeting, enriching, detecting and/or isolating target nucleic acid sequence using reca-like recombinase |
| US5948653A (en) | 1997-03-21 | 1999-09-07 | Pati; Sushma | Sequence alterations using homologous recombination |
| EP2327797B1 (de) | 1997-04-01 | 2015-11-25 | Illumina Cambridge Limited | Verfahren zur Vervielfältigung von Nukleinsäuren |
| US6432360B1 (en) | 1997-10-10 | 2002-08-13 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6511803B1 (en) | 1997-10-10 | 2003-01-28 | President And Fellows Of Harvard College | Replica amplification of nucleic acid arrays |
| US6306590B1 (en) | 1998-06-08 | 2001-10-23 | Caliper Technologies Corp. | Microfluidic matrix localization apparatus and methods |
| AR021833A1 (es) | 1998-09-30 | 2002-08-07 | Applied Research Systems | Metodos de amplificacion y secuenciacion de acido nucleico |
| US6699693B1 (en) * | 1999-02-04 | 2004-03-02 | Sloan-Kettering Institute For Cancer Research | Process for DNA replication |
| WO2000046408A1 (en) | 1999-02-04 | 2000-08-10 | Sloan-Kettering Institute For Cancer Research | Process for dna replication |
| GB9902970D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Novel matrix |
| US6531302B1 (en) | 1999-04-12 | 2003-03-11 | Nanogen/Becton Dickinson Partnership | Anchored strand displacement amplification on an electronically addressable microchip |
| US7332308B1 (en) | 1999-05-21 | 2008-02-19 | The Penn State Research Foundation | Incrementally truncated nucleic acids and methods of making same |
| US6440706B1 (en) | 1999-08-02 | 2002-08-27 | Johns Hopkins University | Digital amplification |
| US6413792B1 (en) | 2000-04-24 | 2002-07-02 | Eagle Research Development, Llc | Ultra-fast nucleic acid sequencing device and a method for making and using the same |
| AR031640A1 (es) | 2000-12-08 | 2003-09-24 | Applied Research Systems | Amplificacion isotermica de acidos nucleicos en un soporte solido |
| US6946251B2 (en) | 2001-03-09 | 2005-09-20 | Nugen Technologies, Inc. | Methods and compositions for amplification of RNA sequences using RNA-DNA composite primers |
| ATE397095T1 (de) | 2001-04-20 | 2008-06-15 | Penn State Res Found | Verfahren zur manipulation von nukleinsäuren |
| JP4091304B2 (ja) * | 2002-01-07 | 2008-05-28 | セイコーインスツル株式会社 | 半導体集積回路の製造方法及び半導体集積回路 |
| US7399590B2 (en) * | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| DE60322044D1 (de) * | 2002-02-21 | 2008-08-21 | Asm Scient Inc | Rekombinase-polymerase-amplifikation |
-
2002
- 2002-04-19 AT AT02764202T patent/ATE397095T1/de not_active IP Right Cessation
- 2002-04-19 AU AU2002307371A patent/AU2002307371B2/en not_active Ceased
- 2002-04-19 WO PCT/US2002/012078 patent/WO2002086167A1/en not_active Ceased
- 2002-04-19 US US10/125,973 patent/US6929915B2/en not_active Expired - Lifetime
- 2002-04-19 ES ES02764202T patent/ES2305289T3/es not_active Expired - Lifetime
- 2002-04-19 EP EP02764202A patent/EP1386006B1/de not_active Expired - Lifetime
- 2002-04-19 CA CA2444649A patent/CA2444649C/en not_active Expired - Fee Related
- 2002-04-19 DE DE60226856T patent/DE60226856D1/de not_active Expired - Lifetime
-
2004
- 2004-04-02 US US10/817,560 patent/US20040171060A1/en not_active Abandoned
-
2005
- 2005-06-15 US US11/153,793 patent/US7906279B2/en not_active Expired - Fee Related
- 2005-08-15 US US11/204,125 patent/US7723031B2/en not_active Expired - Fee Related
-
2010
- 2010-05-24 US US12/786,033 patent/US8124342B2/en not_active Expired - Fee Related
- 2010-05-24 US US12/786,053 patent/US8361718B2/en not_active Expired - Fee Related
- 2010-05-24 US US12/785,974 patent/US8129116B2/en not_active Expired - Fee Related
- 2010-05-24 US US12/786,002 patent/US8241851B2/en not_active Expired - Fee Related
- 2010-05-24 US US12/786,021 patent/US8137913B2/en not_active Expired - Fee Related
- 2010-05-24 US US12/786,070 patent/US8389216B2/en not_active Expired - Fee Related
-
2012
- 2012-12-20 US US13/722,738 patent/US8765374B2/en not_active Expired - Fee Related
- 2012-12-20 US US13/722,765 patent/US8759000B2/en not_active Expired - Fee Related
- 2012-12-20 US US13/722,497 patent/US8637243B2/en not_active Expired - Fee Related
- 2012-12-20 US US13/722,617 patent/US8673561B2/en not_active Expired - Fee Related
-
2013
- 2013-12-16 US US14/107,733 patent/US9322057B2/en not_active Expired - Fee Related
-
2014
- 2014-05-02 US US14/268,444 patent/US9322058B2/en not_active Expired - Fee Related
- 2014-06-24 US US14/313,295 patent/US9322059B2/en not_active Expired - Fee Related
- 2014-06-24 US US14/313,193 patent/US9562250B2/en not_active Expired - Fee Related
-
2016
- 2016-03-15 US US15/070,529 patent/US10017803B2/en not_active Expired - Fee Related
- 2016-03-15 US US15/070,401 patent/US10000781B2/en not_active Expired - Fee Related
-
2018
- 2018-05-31 US US15/993,901 patent/US20180265906A1/en not_active Abandoned
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |