ATE393238T1 - Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind - Google Patents

Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind

Info

Publication number
ATE393238T1
ATE393238T1 AT02762370T AT02762370T ATE393238T1 AT E393238 T1 ATE393238 T1 AT E393238T1 AT 02762370 T AT02762370 T AT 02762370T AT 02762370 T AT02762370 T AT 02762370T AT E393238 T1 ATE393238 T1 AT E393238T1
Authority
AT
Austria
Prior art keywords
diabetes
type
sequence variants
receptor sequence
variants associated
Prior art date
Application number
AT02762370T
Other languages
English (en)
Inventor
Daniel Mirel
Henry Erlich
Teodorica Bugawan
Janelle Noble
Ana Valdez
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE393238T1 publication Critical patent/ATE393238T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes
AT02762370T 2001-07-20 2002-07-17 Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind ATE393238T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30691201P 2001-07-20 2001-07-20

Publications (1)

Publication Number Publication Date
ATE393238T1 true ATE393238T1 (de) 2008-05-15

Family

ID=23187422

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02762370T ATE393238T1 (de) 2001-07-20 2002-07-17 Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind

Country Status (7)

Country Link
US (1) US20030152951A1 (de)
EP (1) EP1412531B1 (de)
JP (1) JP2004535822A (de)
AT (1) ATE393238T1 (de)
CA (1) CA2451394C (de)
DE (1) DE60226244T2 (de)
WO (1) WO2003010335A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7205106B1 (en) * 2001-07-20 2007-04-17 Roche Molecular Systems, Inc. Association of polymorphisms in IL4-related genes with autoimmune disease
JPWO2006051886A1 (ja) * 2004-11-12 2008-05-29 国立大学法人大阪大学 組織破壊によって機能障害を来たす自己免疫疾患の重症化の可能性を予測する方法
US20090148843A1 (en) * 2005-10-13 2009-06-11 Hendrik Schulze-Koops Means and Methods for the Prediction of Joint Destruction
GB0523276D0 (en) * 2005-11-15 2005-12-21 London Bridge Fertility Chromosomal analysis by molecular karyotyping
EP2291544B1 (de) * 2008-05-16 2017-10-25 The Children's Hospital of Philadelphia Genetische veränderungen auf chromosomen 21q, 6q und 15q sowie verfahren zur verwendung davon bei der diagnose und behandlung von typ-i-diabetes

Also Published As

Publication number Publication date
CA2451394A1 (en) 2003-02-06
DE60226244D1 (de) 2008-06-05
EP1412531A2 (de) 2004-04-28
WO2003010335A2 (en) 2003-02-06
CA2451394C (en) 2010-02-02
DE60226244T2 (de) 2009-06-25
US20030152951A1 (en) 2003-08-14
JP2004535822A (ja) 2004-12-02
WO2003010335A3 (en) 2003-10-30
EP1412531B1 (de) 2008-04-23

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