WO2003094848A3 - Nucleic acid-associated proteins - Google Patents

Nucleic acid-associated proteins Download PDF

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Publication number
WO2003094848A3
WO2003094848A3 PCT/US2003/014450 US0314450W WO03094848A3 WO 2003094848 A3 WO2003094848 A3 WO 2003094848A3 US 0314450 W US0314450 W US 0314450W WO 03094848 A3 WO03094848 A3 WO 03094848A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
naap
associated proteins
polynucleotides
agonists
Prior art date
Application number
PCT/US2003/014450
Other languages
French (fr)
Other versions
WO2003094848A2 (en
Inventor
Amy E Kable
Vicki S Elliott
Uyen K Tran
Jayalaxmi Ramkumar
Joseph P Marquis
Narinder K Chawla
Original Assignee
Incyte Corp
Amy E Kable
Vicki S Elliott
Uyen K Tran
Jayalaxmi Ramkumar
Joseph P Marquis
Narinder K Chawla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Corp, Amy E Kable, Vicki S Elliott, Uyen K Tran, Jayalaxmi Ramkumar, Joseph P Marquis, Narinder K Chawla filed Critical Incyte Corp
Priority to AU2003232086A priority Critical patent/AU2003232086A1/en
Publication of WO2003094848A2 publication Critical patent/WO2003094848A2/en
Publication of WO2003094848A3 publication Critical patent/WO2003094848A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)

Abstract

Various embodiments of the invention provide human nucleic acid associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
PCT/US2003/014450 2002-05-10 2003-05-09 Nucleic acid-associated proteins WO2003094848A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2003232086A AU2003232086A1 (en) 2002-05-10 2003-05-09 Nucleic acid-associated proteins

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US37984302P 2002-05-10 2002-05-10
US60/379,843 2002-05-10
US38345702P 2002-05-24 2002-05-24
US60/383,457 2002-05-24
US38469902P 2002-05-31 2002-05-31
US60/384,699 2002-05-31
US38726502P 2002-06-06 2002-06-06
US60/387,265 2002-06-06

Publications (2)

Publication Number Publication Date
WO2003094848A2 WO2003094848A2 (en) 2003-11-20
WO2003094848A3 true WO2003094848A3 (en) 2004-07-01

Family

ID=29424760

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/014450 WO2003094848A2 (en) 2002-05-10 2003-05-09 Nucleic acid-associated proteins

Country Status (2)

Country Link
AU (1) AU2003232086A1 (en)
WO (1) WO2003094848A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005077974A1 (en) * 2004-02-17 2005-08-25 National Public Health Institute IDENTIFICATION OF SNPs ASSOCIATED WITH HYPERLIPIDEMIA, DYSLIPIDEMIA AND DEFECTIVE CARBOHYDRATE METABOLISM
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
EP1742060A1 (en) * 2005-01-24 2007-01-10 DIGILAB BioVisioN GmbH TIF1-beta peptides and nucleic acids for diagnosis and therapy of cancer and colorectal cancerous disorders.
CA2755784C (en) 2009-03-16 2020-03-24 Pangu Biopharma Limited Compositions and methods comprising histidyl-trna synthetase splice variants having non-canonical biological activities
NZ607996A (en) 2010-09-22 2014-07-25 Alios Biopharma Inc Substituted nucleotide analogs
EP2794630A4 (en) 2011-12-22 2015-04-01 Alios Biopharma Inc Substituted phosphorothioate nucleotide analogs
WO2013142157A1 (en) 2012-03-22 2013-09-26 Alios Biopharma, Inc. Pharmaceutical combinations comprising a thionucleotide analog
JP2020517638A (en) 2017-04-20 2020-06-18 エータイアー ファーマ， インコーポレイテッド Compositions and methods for treating lung inflammation
WO2018237300A1 (en) * 2017-06-22 2018-12-27 Board Of Regents, The University Of Texas System Methods for producing regulatory immune cells and uses thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BAES M. ET AL.: "A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements", MOLECULAR AND CELLULAR BIOLOGY, vol. 14, no. 3, May 1994 (1994-05-01), pages 1544 - 1552, XP000613954 *
WEI P. ET AL.: "The nuclear receptor CAR mediates specific xenobiotic induction of drug metabolism", NATURE, vol. 407, 19 October 2000 (2000-10-19), pages 920 - 923, XP000999432 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9127268B2 (en) 2009-12-11 2015-09-08 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9328340B2 (en) 2009-12-11 2016-05-03 Atyr Pharma, Inc. Amino acyl tRNA synthetases for modulating inflammation
US9540628B2 (en) 2009-12-11 2017-01-10 Atyr Pharma, Inc. Aminoacyl tRNA synthetases for modulating inflammation
US9422539B2 (en) 2010-07-12 2016-08-23 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-tRNA synthetases
US8835387B2 (en) 2012-02-16 2014-09-16 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9273302B2 (en) 2012-02-16 2016-03-01 Atyr Pharma, Inc. Histidyl-tRNA synthetases for treating autoimmune and inflammatory diseases
US9394330B2 (en) 2012-03-21 2016-07-19 Alios Biopharma, Inc. Solid forms of a thiophosphoramidate nucleotide prodrug
US9587235B2 (en) 2013-03-15 2017-03-07 Atyr Pharma, Inc. Histidyl-tRNA synthetase-Fc conjugates

Also Published As

Publication number Publication date
AU2003232086A1 (en) 2003-11-11
WO2003094848A2 (en) 2003-11-20
AU2003232086A8 (en) 2003-11-11

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