DE60226244D1 - Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind - Google Patents

Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind

Info

Publication number
DE60226244D1
DE60226244D1 DE60226244T DE60226244T DE60226244D1 DE 60226244 D1 DE60226244 D1 DE 60226244D1 DE 60226244 T DE60226244 T DE 60226244T DE 60226244 T DE60226244 T DE 60226244T DE 60226244 D1 DE60226244 D1 DE 60226244D1
Authority
DE
Germany
Prior art keywords
diabetes
type
sequence variants
receptor sequence
variants associated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60226244T
Other languages
English (en)
Other versions
DE60226244T2 (de
Inventor
Daniel B Mirel
Henry A Erlich
Teodorica L Bugawan
Janelle A Noble
Ana Maria Valdez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Roche Diagnostics GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roche Diagnostics GmbH filed Critical Roche Diagnostics GmbH
Publication of DE60226244D1 publication Critical patent/DE60226244D1/de
Application granted granted Critical
Publication of DE60226244T2 publication Critical patent/DE60226244T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/172Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE60226244T 2001-07-20 2002-07-17 Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind Expired - Lifetime DE60226244T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30691201P 2001-07-20 2001-07-20
US306912P 2001-07-20
PCT/EP2002/007956 WO2003010335A2 (en) 2001-07-20 2002-07-17 Il-4 receptor sequence variation associated with type 1 diabetes

Publications (2)

Publication Number Publication Date
DE60226244D1 true DE60226244D1 (de) 2008-06-05
DE60226244T2 DE60226244T2 (de) 2009-06-25

Family

ID=23187422

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60226244T Expired - Lifetime DE60226244T2 (de) 2001-07-20 2002-07-17 Il-4 rezeptor sequenzvarianten, die mit typ i diabetes assoziiert sind

Country Status (7)

Country Link
US (1) US20030152951A1 (de)
EP (1) EP1412531B1 (de)
JP (1) JP2004535822A (de)
AT (1) ATE393238T1 (de)
CA (1) CA2451394C (de)
DE (1) DE60226244T2 (de)
WO (1) WO2003010335A2 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7205106B1 (en) * 2001-07-20 2007-04-17 Roche Molecular Systems, Inc. Association of polymorphisms in IL4-related genes with autoimmune disease
JPWO2006051886A1 (ja) * 2004-11-12 2008-05-29 国立大学法人大阪大学 組織破壊によって機能障害を来たす自己免疫疾患の重症化の可能性を予測する方法
EP2380994A1 (de) * 2005-10-13 2011-10-26 Hendrik Schulze-Koops Mittel und Verfahren zur Vorhersage einer Gelenkzerstörung
GB0523276D0 (en) * 2005-11-15 2005-12-21 London Bridge Fertility Chromosomal analysis by molecular karyotyping
AU2009246134B2 (en) 2008-05-16 2016-03-03 The Children's Hospital Of Philadelphia Genetic alterations on chromosomes 21q, 6q and 15q and methods of use thereof for the diagnosis and treatment of type I diabetes

Also Published As

Publication number Publication date
WO2003010335A2 (en) 2003-02-06
JP2004535822A (ja) 2004-12-02
CA2451394A1 (en) 2003-02-06
EP1412531A2 (de) 2004-04-28
DE60226244T2 (de) 2009-06-25
WO2003010335A3 (en) 2003-10-30
US20030152951A1 (en) 2003-08-14
EP1412531B1 (de) 2008-04-23
ATE393238T1 (de) 2008-05-15
CA2451394C (en) 2010-02-02

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Legal Events

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